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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance White or off-white powder Off-white powder Identification HPLC

High purity Various Specifications Indazole-3-carboxylic acid CAS:4498-67-3

Cas:4498-67-3

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 1H-Indazole-3-Carboxylic Acid supplier in China

Cas:4498-67-3

Min.Order:0 Metric Ton

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Indazole-3-carboxylic acid CAS NO.4498-67-3

Cas:4498-67-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of Indazole-3-carboxylic acid Cas 4498-67-3 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or pale yellow crystalline powder Storage:Cool dry place P

High quality Indazole-3-carboxylic acid Cas 4498-67-3 with best price and good service

Cas:4498-67-3

Min.Order:1 Kilogram

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Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1H-indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Indazole-3-carboxylic acid 4498-67-3 ISO Producer

Cas:4498-67-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:1 Kilogram

FOB Price: $6.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Indazolecarboxylic acid

Cas:4498-67-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Indazole-3-carboxylic acid 4498-67-3 Indazole-3-carboxylic acid Basic information Product Name: Indazole-3-carboxylic acid Synonyms: 1H-INDAZOL-3-CARBONIC ACID;1H-INDAZOLE-3-CARBOXYLIC

TIANFU-CHEM Indazole-3-carboxylic acid 4498-67-3

Cas:4498-67-3

Min.Order:1 Metric Ton

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Type:Lab/Research institutions

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Jinan Finer Chemical Co., Ltd

Product Description Product name Indazole-3-carboxylic acid CAS 4498-67-3 Assay 99% Appearance Yellow c

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

Indazole-3-Carboxylic Acid 4498-67-3 3-CARBOXYINDAZOLE

Cas:4498-67-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 4498-67-3 with best quality

Cas:4498-67-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:1 Kilogram

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:1 Metric Ton

FOB Price: $68.0 / 78.0

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Henan Sinotech Import&Export Corporation

CAS No. 4498-67-3 Other Names 1h-indazole-3-carboxylic Acid MF C8H6N2O2 EINECS No. 224-794-5 Type Dyestuff Intermediates, Pharmaceutical Int

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Powder Storage:Store in sealed containers at cool & dr

Indazole-3-carboxylic acid CAS 4498-67-3

Cas:4498-67-3

Min.Order:100 Gram

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Type:Other

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Hangzhou Think Chemical Co. Ltd

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exp

Manufacturer Indazole-3-carboxylic acid CAS NO.:4498-67-3 best price, fresh stock

Cas:4498-67-3

Min.Order:1 Kilogram

FOB Price: $10.0 / 20.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical inte

Top supplier Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:100 Gram

FOB Price: $10.0

Type:Lab/Research institutions

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

Indazole-3-carboxylic acid/ LIDE PHARMA- Factory supply / Best price

Cas:4498-67-3

Min.Order:1 Kilogram

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Qingdao Beluga Import and Export Co., LTD

7-Hydroxygranisetron CAS: 4498-67-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte

7-Hydroxygranisetron CAS: 4498-67-3

Cas:4498-67-3

Min.Order:1 Gram

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Leader Biochemical Group

PRODUCT DETAILS 7-Hydroxygranisetron Basic information Product Name: 7-Hydroxygranisetron Synonyms: 1H-INDAZOL-3

China Largest Manufacturer factory sales Indazole-3-carboxylic acid CAS 4498-67-3

Cas:4498-67-3

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:0

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HANGZHOU YUNUO CHEMICAL CO.,LTD

Hangzhou Yunuo Chemical Co., Ltd is located in Hangzhou city China. As a global supplier in the chemical industry, Yunuochem is to create added value for customers around the world. Sticking to such business idea of "Good faith wins the business

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:10 Gram

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Type:Trading Company

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Hebei Miheng Trading Co., Ltd.

7-Hydroxygranisetron cas 4498-67-3 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembl

7-Hydroxygranisetron cas 4498-67-3

Cas:4498-67-3

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:Yellow crystalline powder Storage:R.T Package:25kg/drum Application:Intermediate Transportation:Express/Sea/Air Port:Any port in China

99% Indazole-3-carboxylic acid cas 4498-67-3

Cas:4498-67-3

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Indazole-3-Carboxylic Acid

Cas:4498-67-3

Min.Order:0

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Type:Manufacturers

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Triumph International Development Limilted

Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and quality c

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:100 Metric Ton

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Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:0 Metric Ton

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:10 Kilogram

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Type:Trading Company

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Name Indazole-3-carboxylic acid Synonyms 1H-Indazole-3-carboxylic acid Molecular Structure Molecular Formula

Indazole-3-carboxylic acid

Cas:4498-67-3

Min.Order:0 Metric Ton

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Type:Other

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Synthetic route

indole-2,3-dione
91-56-5

indole-2,3-dione

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: indole-2,3-dione With sodium hydroxide In water at 20 - 50℃; for 1.5h;
Stage #2: With sulfuric acid; sodium nitrite In water at 0℃; for 1h;
Stage #3: With hydrogenchloride; tin(ll) chloride In water for 1.16667h;
100%
With sodium hydroxide; sulfuric acid; sulfur dioxide; sodium nitrite Reagens 4: Zinnchloruer;
With sulfuric acid; sodium nitrite danach SnCl2;
methyl 1-acetylindazole-3-carboxylate
186966-06-3

methyl 1-acetylindazole-3-carboxylate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide In hydrogenchloride; water100%
With sodium hydroxide; water for 1.5h; Heating;97%
ethyl 1-acetyl-1H-indazole-3-carboxylate
78155-12-1

ethyl 1-acetyl-1H-indazole-3-carboxylate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide; water for 1.5h; Heating;98%
1-(3-(morpholine-4-carbonyl)-1H-indazol-1-yl)ethanone
186966-03-0

1-(3-(morpholine-4-carbonyl)-1H-indazol-1-yl)ethanone

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide; water for 3h; Heating;96%
4-bromobenzylideneaminoisatine
1630015-70-1

4-bromobenzylideneaminoisatine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: 4-bromobenzylideneaminoisatine With hydrogenchloride In water; acetic acid at 90 - 100℃; for 1h;
Stage #2: With acetic acid at 115℃; for 1h;
85%
1-(benzylideneamino)indoline-2,3-dione
10604-20-3

1-(benzylideneamino)indoline-2,3-dione

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride; acetic acid In dichloromethane; ISOPROPYLAMIDE; water at 15 - 90℃; Product distribution / selectivity; Reflux; Inert atmosphere;76%
Stage #1: 1-(benzylideneamino)indoline-2,3-dione With hydrogenchloride; acetic acid In water at 90℃; for 1h;
Stage #2: With acetic acid at 115℃; for 0.5h;
71%
3-(hydroxymethyl)-1H-indazole
64132-13-4

3-(hydroxymethyl)-1H-indazole

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With chromium(VI) oxide; sulfuric acid In acetone at 20℃; for 24h;64%
With chromium(VI) oxide; sulfuric acid In acetone at 20℃; for 24h;64%
tin(II)chloride dihydrate

tin(II)chloride dihydrate

indole-2,3-dione
91-56-5

indole-2,3-dione

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With sodium hydroxide; sulfuric acid; sodium nitrite In hydrogenchloride; water31%
1-dimethylamino-indolin-2-one
861798-91-6

1-dimethylamino-indolin-2-one

2,3-dimethyl-4-nitroso-aniline
871876-73-2

2,3-dimethyl-4-nitroso-aniline

sodium ethanolate
141-52-6

sodium ethanolate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

1-benzylideneamino-indole-2,3-dione
10604-20-3

1-benzylideneamino-indole-2,3-dione

acetic acid
64-19-7

acetic acid

A

benzaldehyde
100-52-7

benzaldehyde

B

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
mit Wasserdampf;
indazole-3-carbonitrile
50264-88-5

indazole-3-carbonitrile

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride
N-acetylaminoisatin
123704-99-4

N-acetylaminoisatin

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With sulfuric acid for 2.5h; Heating;
sulfuric acid
7664-93-9

sulfuric acid

1-acetylamino-indoline-2,3-dione-3-oxime

1-acetylamino-indoline-2,3-dione-3-oxime

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

N-acetylamino-isatin-β oxime

N-acetylamino-isatin-β oxime

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With sulfuric acid
N-benzylidenamino-isatin

N-benzylidenamino-isatin

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
With hydrogenchloride
hydrogenchloride
7647-01-0

hydrogenchloride

1-benzylideneamino-indole-2,3-dione
10604-20-3

1-benzylideneamino-indole-2,3-dione

A

benzaldehyde
100-52-7

benzaldehyde

B

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
mit Wasserdampf;
oxalic acid-(benzylidene-phenyl-hydrazide)-chloride
109411-83-8

oxalic acid-(benzylidene-phenyl-hydrazide)-chloride

A

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

B

N-benzylidenamino-isatin

N-benzylidenamino-isatin

Conditions
ConditionsYield
With carbon disulfide; aluminium trichloride
2-(2-nitrophenyl)acetic acid
3740-52-1

2-(2-nitrophenyl)acetic acid

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 95 percent / cc. H2SO4 / 4 h / Heating
2: 97 percent / H2 / 5percent Pd/C / toluene / Ambient temperature
3: 87 percent / 90percent t-BuONO / acetic acid / 0.5 h / 90 - 95 °C
4: 97 percent / NaOH, water / 1.5 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 94 percent / cc. H2SO4 / 4 h / Heating
2: 97 percent / H2 / 5percent Pd/C / toluene / Ambient temperature
3: 83 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
4: 98 percent / NaOH, water / 1.5 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 89 percent / SOCl2 / dimethylformamide; 1,2-dichloro-ethane / 35-40 deg C, 2 h then 20 deg C, 2 h
2: 95 percent / H2 / 5percent Pd/C / toluene / Ambient temperature
3: 76 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
4: 96 percent / NaOH, water / 3 h / Heating
View Scheme
Multi-step reaction with 5 steps
1: 89 percent / SOCl2 / dimethylformamide; 1,2-dichloro-ethane / 35-40 deg C, 2 h then 20 deg C, 2 h
2: 92 percent / Fe, aq. NH4Cl / propan-2-ol / 1 h / Heating
3: toluene / rt to 95 deg C
4: 76 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
5: 96 percent / NaOH, water / 3 h / Heating
View Scheme
methyl (2-nitrophenyl)acetate
30095-98-8

methyl (2-nitrophenyl)acetate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 97 percent / H2 / 5percent Pd/C / toluene / Ambient temperature
2: 87 percent / 90percent t-BuONO / acetic acid / 0.5 h / 90 - 95 °C
3: 97 percent / NaOH, water / 1.5 h / Heating
View Scheme
ethyl 2-nitrophenylacetate
31912-02-4

ethyl 2-nitrophenylacetate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 97 percent / H2 / 5percent Pd/C / toluene / Ambient temperature
2: 83 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
3: 98 percent / NaOH, water / 1.5 h / Heating
View Scheme
(2-acetylamino-phenyl)-acetic acid ethyl ester
186966-08-5

(2-acetylamino-phenyl)-acetic acid ethyl ester

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 83 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
2: 98 percent / NaOH, water / 1.5 h / Heating
View Scheme
methyl 3-(2-acetamidophenyl)propanoate
134810-89-2

methyl 3-(2-acetamidophenyl)propanoate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 87 percent / 90percent t-BuONO / acetic acid / 0.5 h / 90 - 95 °C
2: 97 percent / NaOH, water / 1.5 h / Heating
View Scheme
4-[(2-nitro-phenyl)-acetyl]-morpholine
25888-16-8

4-[(2-nitro-phenyl)-acetyl]-morpholine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / H2 / 5percent Pd/C / toluene / Ambient temperature
2: 76 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
3: 96 percent / NaOH, water / 3 h / Heating
View Scheme
Multi-step reaction with 4 steps
1: 92 percent / Fe, aq. NH4Cl / propan-2-ol / 1 h / Heating
2: toluene / rt to 95 deg C
3: 76 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
4: 96 percent / NaOH, water / 3 h / Heating
View Scheme
4-(2-aminophenylacetyl)morpholine
80798-83-0

4-(2-aminophenylacetyl)morpholine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: toluene / rt to 95 deg C
2: 76 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
3: 96 percent / NaOH, water / 3 h / Heating
View Scheme
N-[2-(2-Morpholin-4-yl-2-oxo-ethyl)-phenyl]-acetamide
186966-07-4

N-[2-(2-Morpholin-4-yl-2-oxo-ethyl)-phenyl]-acetamide

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 76 percent / 90percent t-BuONO / toluene / 0.5 h / 90 - 95 °C
2: 96 percent / NaOH, water / 3 h / Heating
View Scheme
N-Acetylaminoisonitrosoacetanilide
123704-98-3

N-Acetylaminoisonitrosoacetanilide

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 96percent H2SO4 / 0.25 h / 85 °C
2: aq. H2SO4 / 2.5 h / Heating
View Scheme
1-acetyl-2-phenylhydrazine
114-83-0

1-acetyl-2-phenylhydrazine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 79 percent / hydroxylamine hydrochloride, sodium sulphate, 1 N HCl / H2O / 0.17 h / 100 °C
2: 96percent H2SO4 / 0.25 h / 85 °C
3: aq. H2SO4 / 2.5 h / Heating
View Scheme
2-nitro-benzeneacetonitrile
610-66-2

2-nitro-benzeneacetonitrile

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: tin; hydrochloric acid
2: acid; sodium nitrite
3: concentrated hydrochloric acid
View Scheme
2-aminophenylacetonitrile
2973-50-4

2-aminophenylacetonitrile

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: acid; sodium nitrite
2: concentrated hydrochloric acid
View Scheme
p-toluidine
106-49-0

p-toluidine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

N-(p-tolyl)-1H-indazole-3-carboxamide

N-(p-tolyl)-1H-indazole-3-carboxamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃;100%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃; for 10h;66%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

4-methoxycarbonyl aniline
619-45-4

4-methoxycarbonyl aniline

methyl 4-(1H-indazole-3-carboxamido)benzoate

methyl 4-(1H-indazole-3-carboxamido)benzoate

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃;100%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃; for 10h;10%
4-chloro-aniline
106-47-8

4-chloro-aniline

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

N-(4-chlorophenyl)-1H-indazole-3-carboxamide
23707-00-8

N-(4-chlorophenyl)-1H-indazole-3-carboxamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃;100%
methanol
67-56-1

methanol

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

methyl 1H-indazole-3-carboxylate
43120-28-1

methyl 1H-indazole-3-carboxylate

Conditions
ConditionsYield
With sulfuric acid for 2h; Heating;98%
With sulfuric acid for 2h; Reflux;95%
With thionyl chloride for 3h; Reflux;95%
5,6-diamino-1-ethyl-3,3-dimethylindol-2-one
881693-01-2

5,6-diamino-1-ethyl-3,3-dimethylindol-2-one

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

5-ethyl-2-(1H-indazol-3-yl)-7,7-dimethyl-5,7-dihydro-3H-imidazo[4,5-f]indol-6-one

5-ethyl-2-(1H-indazol-3-yl)-7,7-dimethyl-5,7-dihydro-3H-imidazo[4,5-f]indol-6-one

Conditions
ConditionsYield
Stage #1: 5,6-diamino-1-ethyl-3,3-dimethylindol-2-one; 1H-Indazole-3-carboxylic acid With PPA; phosphorus pentoxide at 150℃; for 6h;
Stage #2: With ammonia In water pH=7 - 8;
97%
endo-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine
76272-41-8, 141650-55-7, 76272-56-5

endo-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

endo-N-(9-methyl-9-azabicyclo<3.3.1>nonan-3-yl)-1H-indazole-3-carboxamide
107007-95-4

endo-N-(9-methyl-9-azabicyclo<3.3.1>nonan-3-yl)-1H-indazole-3-carboxamide

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: endo-9-methyl-9-azabicyclo[3.3.1]nonan-3-amine In dichloromethane; N,N-dimethyl-formamide at 20℃; Inert atmosphere;
97%
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 20℃;73%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

methyl 1H-indazole-3-carboxylate
43120-28-1

methyl 1H-indazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With potassium carbonate In acetone at 20℃; for 0.166667h;
Stage #2: dimethyl sulfate In acetone for 4h; Reflux;
95%
Phenylpropargyl aldehyde
2579-22-8

Phenylpropargyl aldehyde

Benzyl isocyanide
88333-03-3, 10340-91-7

Benzyl isocyanide

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

4-bromo-aniline
106-40-1

4-bromo-aniline

N,4-dibenzyl-2-(4-bromophenyl)-1-oxo-1,2-dihydropyrazino[1,2-b]indazole-3-carboxamide

N,4-dibenzyl-2-(4-bromophenyl)-1-oxo-1,2-dihydropyrazino[1,2-b]indazole-3-carboxamide

Conditions
ConditionsYield
Stage #1: Phenylpropargyl aldehyde; 4-bromo-aniline In 2,2,2-trifluoroethanol at 20℃; for 0.166667h; Microwave irradiation;
Stage #2: Benzyl isocyanide; 1H-Indazole-3-carboxylic acid In N,N-dimethyl-formamide at 20 - 110℃; Microwave irradiation;
95%
oxetan-3-yl-methylamine
952182-03-5

oxetan-3-yl-methylamine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

N-methyl-N-(oxetan-3-yl)-1H-indazole-3-carboxamide

N-methyl-N-(oxetan-3-yl)-1H-indazole-3-carboxamide

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 24h; Reagent/catalyst; Temperature; Solvent;94%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

methylamine
74-89-5

methylamine

1-methyl-3-indolecarboxylic acid
32387-21-6

1-methyl-3-indolecarboxylic acid

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With tin(ll) chloride In acetonitrile at 55℃; for 6h;
Stage #2: methylamine In acetonitrile at 9℃; for 41h; Temperature; Reflux;
93%
tert-butyl [2-amino-2-(hydroxyimino)ethyl]carbamate
479079-15-7, 479080-20-1

tert-butyl [2-amino-2-(hydroxyimino)ethyl]carbamate

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

tert-butyl 2-(1H-indazole-3-carbonyloxyimino)-2-aminoethylcarbamate
1151512-97-8

tert-butyl 2-(1H-indazole-3-carbonyloxyimino)-2-aminoethylcarbamate

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere;
Stage #2: tert-butyl 2-amino-2-(hydroxyimino)ethylcarbamate In N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere;
92%
Stage #1: 1H-Indazole-3-carboxylic acid With 1,1'-carbonyldiimidazole In N,N-dimethyl-formamide at 20℃; for 0.5h; Inert atmosphere;
Stage #2: tert-butyl 2-amino-2-(hydroxyimino)ethylcarbamate In N,N-dimethyl-formamide at 20℃;
92%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

1H-indazole-3-carbonyl chloride
72083-74-0

1H-indazole-3-carbonyl chloride

Conditions
ConditionsYield
With thionyl chloride at 20℃; for 2h; Inert atmosphere;91%
With thionyl chloride for 1h; Reflux;
With oxalyl dichloride; N,N-dimethyl-formamide In dichloromethane for 2h;
With thionyl chloride for 8h; Reflux;
With thionyl chloride at 80℃; for 4h;
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

1-methylindazole-3-carboxylic acid hydrochloride

1-methylindazole-3-carboxylic acid hydrochloride

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With calcium methylate In methanol for 2h; Heating / reflux;
Stage #2: dimethyl sulfate In methanol for 3h; Heating / reflux;
Stage #3: With hydrogenchloride In water for 2h; pH=1;
87.7%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

5-bromobenzopyrazole-3-carboxylic acid
1077-94-7

5-bromobenzopyrazole-3-carboxylic acid

Conditions
ConditionsYield
With bromine; acetic acid at 90 - 120℃; for 16h;87.5%
Stage #1: 1H-Indazole-3-carboxylic acid With acetic acid at 120℃;
Stage #2: With bromine; acetic acid at 90℃; for 16h;
87.5%
With bromine; acetic acid at 90 - 120℃; for 16h;87.5%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

dimethyl sulfate
77-78-1

dimethyl sulfate

1-methyl-1H-indazole-3-carboxylic acid
50890-83-0

1-methyl-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With calcium oxide In methanol for 2h; Heating / reflux;
Stage #2: dimethyl sulfate In methanol for 4h; Heating / reflux;
85.6%
Stage #1: 1H-Indazole-3-carboxylic acid With magnesium n-propylate In propan-1-ol for 2h; Heating / reflux;
Stage #2: dimethyl sulfate In propan-1-ol at 20℃; for 5h; Heating / reflux;
83.8%
Stage #1: 1H-Indazole-3-carboxylic acid With magnesium ethylate In propan-1-ol for 2h; Heating / reflux;
Stage #2: dimethyl sulfate In propan-1-ol at 20℃; for 2h; Heating / reflux;
79.2%
Stage #1: 1H-Indazole-3-carboxylic acid With barium(II) oxide In propan-1-ol for 2h; Heating / reflux;
Stage #2: dimethyl sulfate In propan-1-ol at 20℃; for 2h; Heating / reflux;
65.4%
4-amino-1-benzylpiperidine
50541-93-0

4-amino-1-benzylpiperidine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

N-(1-benzylpiperidin-4-yl)-1H-indazole-3-carboxamide
207296-87-5

N-(1-benzylpiperidin-4-yl)-1H-indazole-3-carboxamide

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With 1,1'-carbonyldiimidazole In DMF (N,N-dimethyl-formamide) at 60℃; for 2h;
Stage #2: 4-amino-1-benzylpiperidine In DMF (N,N-dimethyl-formamide) at 60℃; for 2h;
85.1%
With 1,1'-carbonyldiimidazole 1.) DMF, 60 deg C, 2 h, 2.) DMF, 60 deg C, 2 h; Yield given. Multistep reaction;
In N-methyl-acetamide; dichloromethane; 1,1'-carbonyldiimidazole76%.
N,O-dimethylhydroxylamine*hydrochloride
6638-79-5

N,O-dimethylhydroxylamine*hydrochloride

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

1H-indazole-3-carboxylic acid methoxy(methyl)amide
351457-12-0

1H-indazole-3-carboxylic acid methoxy(methyl)amide

Conditions
ConditionsYield
Stage #1: N,O-dimethylhydroxylamine*hydrochloride; 1H-Indazole-3-carboxylic acid With pyridine In tetrahydrofuran at 20℃; for 3h; Cooling with ice;
Stage #2: With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 20℃;
85%
With pyridine; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide In tetrahydrofuran at 0 - 20℃; for 13.5h;84%
Stage #1: N,O-dimethylhydroxylamine*hydrochloride; 1H-Indazole-3-carboxylic acid With pyridine In tetrahydrofuran at 0 - 20℃; for 2.5h;
Stage #2: With pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In tetrahydrofuran at 20℃;
84%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

methyl 1H-indazole-3-carboxylate
43120-28-1

methyl 1H-indazole-3-carboxylate

Conditions
ConditionsYield
Stage #1: methanol With acetyl chloride at 0℃; for 0.166667h;
Stage #2: 1H-Indazole-3-carboxylic acid at 0 - 20℃;
85%
With sodium bicarbonate; sulfuric acid In methanol61%
In methanol
oxotribromobis(triphenylphosphine)rhenium(V)
18703-07-6, 74741-94-9, 162117-95-5

oxotribromobis(triphenylphosphine)rhenium(V)

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

[ReO(bromide)2(indazole-3-carboxylate)(triphenylphosphine)]*(triphenylphosphine oxide)

[ReO(bromide)2(indazole-3-carboxylate)(triphenylphosphine)]*(triphenylphosphine oxide)

Conditions
ConditionsYield
With air In tetrahydrofuran byproducts: HBr, P(C6H5)3; addn. of Re complex to N compd. (1:1) in C4H8O, heating under reflux for4 h; concn., cooling to room temp., slow diffusion of diethyl ether, isolation of crystals, elem. anal.;85%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

1H-indazole-3-carboxamide
90004-04-9

1H-indazole-3-carboxamide

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at -20℃; for 2h; Inert atmosphere;
Stage #2: With ammonia In tetrahydrofuran; water at 20℃; for 1h;
85%
Stage #1: 1H-Indazole-3-carboxylic acid With 4-methyl-morpholine; isobutyl chloroformate In tetrahydrofuran at -20℃; for 2h; Inert atmosphere;
Stage #2: With ammonia In tetrahydrofuran; water at 20℃; for 1h; Inert atmosphere;
85%
Stage #1: 1H-Indazole-3-carboxylic acid With thionyl chloride for 3h; Inert atmosphere; Reflux;
Stage #2: With ammonia In tetrahydrofuran; water at 20℃; for 0.5h; Inert atmosphere;
76%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

methyl iodide
74-88-4

methyl iodide

1-methyl-1H-indazole-3-carboxylic acid
50890-83-0

1-methyl-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With calcium oxide In methanol for 2h; Heating / reflux;
Stage #2: methyl iodide In methanol at 20℃; for 26h; Heating / reflux;
83.8%
With hydrogenchloride; sodium chloride; sodium hydrogencarbonate In dimethyl sulfoxide; mineral oil
2-methoxy-phenylamine
90-04-0

2-methoxy-phenylamine

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

N-(2-methoxyphenyl)-1H-indazole-3-carboxamide
23707-04-2

N-(2-methoxyphenyl)-1H-indazole-3-carboxamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃; for 10h;82%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃;70%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

4-amino-5-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol
36209-49-1

4-amino-5-(4-methoxyphenyl)-4H-1,2,4-triazole-3-thiol

3-[3-(4-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1H-indazole

3-[3-(4-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-1H-indazole

Conditions
ConditionsYield
With trichlorophosphate at 90 - 95℃;82%
aniline
62-53-3

aniline

1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

1H-indazole-3-carboxylic acid phenylamide
23706-99-2

1H-indazole-3-carboxylic acid phenylamide

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃;81%
Stage #1: 1H-Indazole-3-carboxylic acid With thionyl chloride for 3h; Inert atmosphere; Reflux;
Stage #2: aniline In tetrahydrofuran at 20℃; for 0.5h; Inert atmosphere;
70%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 48h;64%
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 100℃; for 10h;59%
1H-Indazole-3-carboxylic acid
4498-67-3

1H-Indazole-3-carboxylic acid

(±)-(1R,3r,5S)-9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl acetate
76272-58-7

(±)-(1R,3r,5S)-9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl acetate

N-[(3-endo)-9-(phenylmethyl)-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide
1210745-16-6

N-[(3-endo)-9-(phenylmethyl)-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide

Conditions
ConditionsYield
Stage #1: 1H-Indazole-3-carboxylic acid With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 20℃; for 2h;
Stage #2: (±)-(1R,3r,5S)-9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl acetate In dichloromethane; N,N-dimethyl-formamide at 20℃; Inert atmosphere;
81%

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