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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

2-methylglutaronitrile

Cas:4553-62-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 2-methylglutaronitrile

Cas:4553-62-2

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Methylglutaronitrile

Cas:4553-62-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Best price and High quality of 2-METHYLGLUTARONITRILE from HENAN TIANFU CHEMICAL: Henan Tianfu Chemical Co.,LTD was built in 2009 with an ISO certificate in the past 5 years, we have grown up as a famous fine chemicals supplier in china and we ha

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Chinese Standard CAS 4553-62-2 with fast shipping

Cas:4553-62-2

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: 2-Methylpentanedinitrile Synonyms: Methylglutaronitrile CAS: 4553-62-2 MF: C6H8N2 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Pharmaceutical Intermediate Transportation:By s

2-Methylpentanedinitrile

Cas:4553-62-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pentanedinitrile,2-methyl- 4553-62-2

Cas:4553-62-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2-METHYLGLUTARONITRILE CAS:4553-62-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int

2-METHYLGLUTARONITRILE CAS:4553-62-2

Cas:4553-62-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pentanedinitrile,2-methyl-

Cas:4553-62-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. we offer low price custom synthesis and contract manufacturing Advantage cof, mof ligand manufacturer Product Detail

low price 2-Methylglutaronitrile CAS:4553-62-2, C6H8N2

Cas:4553-62-2

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:1 Kilogram

FOB Price: $40.0 / 60.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pentanedinitrile,2-methyl-

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2-methylglutaronitrile

Cas:4553-62-2

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

best price 98%, 99% 2-Methylglutaronitrile CAS:4553-62-2, C6H8N2 CAS NO.4553-62-2

Cas:4553-62-2

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

GIHI CHEMICALS CO.,LIMITED

Lower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe

2-Methylglutaronitrile

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

2-methylglutaronitrile

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Pentanedinitrile,2-methyl-

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pentanedinitrile,2-methyl-

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

(+/-)-2-METHYLGLUTARONITRILECASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(+/-)-2-METHYLGLUTARONITRILECAS

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

4553-62-2

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:White powder Storage:keep sealed and keep from direct light Package:According client's requirements Application:pharmaceutica

2-Methylglutaronitrile manufacturer

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Amadis Chemical Co., Ltd.

1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G

Pentanedinitrile,2-methyl-

Cas:4553-62-2

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

2-METHYLGLUTARONITRILE Basic information Product Name: 2-METHYLGLUTARONITRILE

4553-62-2 C6H8N2 2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Jilin haofei import and export trade Co.,Ltd

Price, service, company and transport advantage: 1. Best service, place of origin China, high quality, and reasonable price. 2. It's customers' right to choose the package (EMS, DHL, FEDEX, UPS). 3. It's customers' right

2-methylglutaronitrile CAS NO.4553-62-2

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

ShiJiaZhuang Simaiou Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

2-METHYLGLUTARONITRILE

Cas:4553-62-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

4-bromovalero-nitrile
14470-12-3

4-bromovalero-nitrile

tetra-n-butylammonium cyanide
10442-39-4

tetra-n-butylammonium cyanide

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With copper(l) iodide In acetonitrile at 20℃; for 24h; Inert atmosphere; UV-irradiation;82%
hydrogen cyanide
74-90-8

hydrogen cyanide

3-pentenenitrile
4635-87-4

3-pentenenitrile

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With dicobalt octacarbonyl; benzene at 130℃;
1,3-dichlorobutane
1190-22-3

1,3-dichlorobutane

sodium cyanide
143-33-9

sodium cyanide

A

4-chloro-valeronitrile
13249-56-4

4-chloro-valeronitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With 2-methoxy-ethanol at 160℃; unter Druck;
With 2-methoxy-ethanol at 159 - 163℃; under 1765.2 - 2059.4 Torr;
1,3-dibromobutane
107-80-2

1,3-dibromobutane

sodium cyanide
143-33-9

sodium cyanide

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With methanol
1,3-dibromobutane
107-80-2

1,3-dibromobutane

potassium cyanide
151-50-8

potassium cyanide

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With ethanol
4-chloro-valeronitrile
13249-56-4

4-chloro-valeronitrile

sodium cyanide
143-33-9

sodium cyanide

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With N,N-dimethyl-formamide
hydrogen cyanide
74-90-8

hydrogen cyanide

buta-1,3-diene
106-99-0

buta-1,3-diene

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With dicobalt octacarbonyl; benzene at 130℃;
2-Methyl-glutaconsaeuredinitril
91808-25-2

2-Methyl-glutaconsaeuredinitril

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
palladium on activated charcoal (hydrogenation);
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

acrylonitrile
107-13-1

acrylonitrile

A

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

B

4,4-dimethoxybutanenitrile
14618-78-1

4,4-dimethoxybutanenitrile

C

propiononitrile
107-12-0

propiononitrile

Conditions
ConditionsYield
With dicobalt octacarbonyl; hydrogen In methanol at 100℃; under 129287 Torr; for 8h; Product distribution; Mechanism; var. catalysts, time and temp.;
carbon monoxide
201230-82-2

carbon monoxide

acrylonitrile
107-13-1

acrylonitrile

cyclohexanol
108-93-0

cyclohexanol

A

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

B

3-Cyano-propionic acid cyclohexyl ester
125847-90-7

3-Cyano-propionic acid cyclohexyl ester

C

Cyano-methyl-acetic acid cyclohexyl ester
125847-86-1

Cyano-methyl-acetic acid cyclohexyl ester

D

2,4-dicyano-2-methylbutanoic acid cyclohexyl ester
125847-81-6

2,4-dicyano-2-methylbutanoic acid cyclohexyl ester

Conditions
ConditionsYield
With pyridine; dicobalt octacarbonyl In toluene at 110℃; under 75005.9 - 90007.2 Torr; for 6h;A n/a
B 5.3 % Chromat.
C 28.9 % Chromat.
D 61.7 % Chromat.
acrylonitrile
107-13-1

acrylonitrile

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
In N,N-dimethyl-formamide Rate constant; Mechanism; electrochemical hydrodimerization;
sulfuric acid
7664-93-9

sulfuric acid

dihydrogen peroxide
7722-84-1

dihydrogen peroxide

iron(II) sulfate

iron(II) sulfate

propiononitrile
107-12-0

propiononitrile

A

meso-2,3-dimethyl-succinonitrile
55903-51-0

meso-2,3-dimethyl-succinonitrile

B

hexanedinitrile
111-69-3

hexanedinitrile

C

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
at 28℃;
2,4-dicyano-2-methyl-butyric acid

2,4-dicyano-2-methyl-butyric acid

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
With pyridine; copper at 110℃;
1,3-dichlorobutane
1190-22-3

1,3-dichlorobutane

sodium cyanide
143-33-9

sodium cyanide

glycolmethyl ether

glycolmethyl ether

A

4-chloro-valeronitrile
13249-56-4

4-chloro-valeronitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
at 159 - 163℃; unter Druck;
hydrogen cyanide
74-90-8

hydrogen cyanide

4-Pentenenitrile
592-51-8

4-Pentenenitrile

A

hexanedinitrile
111-69-3

hexanedinitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

C

alpha-ethylsuccinonitrile
17611-82-4

alpha-ethylsuccinonitrile

Conditions
ConditionsYield
With {2-[(o-tolyl-O)2-P-O]-5-(1,1,3,3-Me4-butyl)benzene}2-SO2; Lewis acid; bis(1,5-cyclooctadiene)nickel (0) In N,N-dimethyl-formamide at 70℃; for 2h; sonication;
3-Pentenenitrile
16529-66-1

3-Pentenenitrile

2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

A

hexanedinitrile
111-69-3

hexanedinitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

C

alpha-ethylsuccinonitrile
17611-82-4

alpha-ethylsuccinonitrile

Conditions
ConditionsYield
With [BMMI][Tf2N]; tri-m-tolyl phosphite; zinc(II) chloride; bis(1,5-cyclooctadiene)nickel (0) at 70℃; for 3h; Product distribution; Further Variations:; Reagents; S;
hydrogen cyanide
74-90-8

hydrogen cyanide

cis-2-pentenenitrile
25899-50-7

cis-2-pentenenitrile

A

hexanedinitrile
111-69-3

hexanedinitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

C

alpha-ethylsuccinonitrile
17611-82-4

alpha-ethylsuccinonitrile

Conditions
ConditionsYield
With zinc(II) chloride In toluene at 50℃; for 16h; Conversion of starting material;
With iron(II) chloride; C54H64O6P2 In toluene at 50℃; for 6h; Conversion of starting material;
With iron(II) chloride In toluene at 25℃; for 72h; Conversion of starting material;
2-acetoxy-2-methyl-glutaronitrile
100377-27-3

2-acetoxy-2-methyl-glutaronitrile

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 500 °C
2: Pd-C / (hydrogenation)
View Scheme
hydrogen cyanide
74-90-8

hydrogen cyanide

cis-2-pentenenitrile
25899-50-7

cis-2-pentenenitrile

2-pentenenitrile
26294-98-4

2-pentenenitrile

3-Pentenenitrile
16529-66-1

3-Pentenenitrile

tiglonitrile
30574-97-1

tiglonitrile

4-Pentenenitrile
592-51-8

4-Pentenenitrile

(Z)-pent-2-enenitrile
16545-78-1

(Z)-pent-2-enenitrile

A

pentanonitrile
110-59-8

pentanonitrile

B

hexanedinitrile
111-69-3

hexanedinitrile

C

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

D

4-ethenylcyclohexene
100-40-3

4-ethenylcyclohexene

Conditions
ConditionsYield
C48H52O4P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite; zinc(II) chloride Product distribution / selectivity;
C44H44O6P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite; zinc(II) chloride Product distribution / selectivity;
(Z)-2-Butene
590-18-1

(Z)-2-Butene

hydrogen cyanide
74-90-8

hydrogen cyanide

hexanedinitrile
111-69-3

hexanedinitrile

buta-1,3-diene
106-99-0

buta-1,3-diene

A

cis-2-pentenenitrile
25899-50-7

cis-2-pentenenitrile

B

2-pentenenitrile
26294-98-4

2-pentenenitrile

C

3-Pentenenitrile
16529-66-1

3-Pentenenitrile

D

(Z)-2-methyl-2-butenenitrile
20068-02-4

(Z)-2-methyl-2-butenenitrile

E

tiglonitrile
30574-97-1

tiglonitrile

F

4-Pentenenitrile
592-51-8

4-Pentenenitrile

G

2-METHYL-3-BUTENENITRILE
16529-56-9

2-METHYL-3-BUTENENITRILE

H

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

I

4-ethenylcyclohexene
100-40-3

4-ethenylcyclohexene

J

(Z)-pent-2-enenitrile
16545-78-1

(Z)-pent-2-enenitrile

Conditions
ConditionsYield
Stage #1: (Z)-2-Butene; hydrogen cyanide; hexanedinitrile; buta-1,3-diene; C42H40O6P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite at 99.84℃;
Stage #2: nickel at 109.84℃; Product distribution / selectivity;
C48H52O4P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite at 89.84℃; Product distribution / selectivity;
(Z)-2-Butene
590-18-1

(Z)-2-Butene

hydrogen cyanide
74-90-8

hydrogen cyanide

buta-1,3-diene
106-99-0

buta-1,3-diene

A

1-butylene
106-98-9

1-butylene

B

cis-2-pentenenitrile
25899-50-7

cis-2-pentenenitrile

C

2-pentenenitrile
26294-98-4

2-pentenenitrile

D

3-Pentenenitrile
16529-66-1

3-Pentenenitrile

E

(Z)-2-methyl-2-butenenitrile
20068-02-4

(Z)-2-methyl-2-butenenitrile

F

tiglonitrile
30574-97-1

tiglonitrile

G

4-Pentenenitrile
592-51-8

4-Pentenenitrile

H

2-METHYL-3-BUTENENITRILE
16529-56-9

2-METHYL-3-BUTENENITRILE

I

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

J

4-ethenylcyclohexene
100-40-3

4-ethenylcyclohexene

K

(Z)-pent-2-enenitrile
16545-78-1

(Z)-pent-2-enenitrile

Conditions
ConditionsYield
Stage #1: (Z)-2-Butene; hydrogen cyanide; buta-1,3-diene; C48H52O4P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite at 83.84℃;
Stage #2: at 119.84℃; Product distribution / selectivity;
Stage #1: (Z)-2-Butene; hydrogen cyanide; buta-1,3-diene; C42H40O6P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite at 89.84℃;
Stage #2: zinc(II) chloride at 109.84℃; Product distribution / selectivity;
Stage #1: (Z)-2-Butene; hydrogen cyanide; buta-1,3-diene; C42H40O6P2; nickel(0)(cyclooctadienyl)2-complex at 89.84℃;
Stage #2: C42H40O6P2; nickel(0)(cyclooctadienyl)2-complex at 109.84℃; Product distribution / selectivity;
(Z)-2-Butene
590-18-1

(Z)-2-Butene

hydrogen cyanide
74-90-8

hydrogen cyanide

buta-1,3-diene
106-99-0

buta-1,3-diene

A

1-butylene
106-98-9

1-butylene

B

cis-2-pentenenitrile
25899-50-7

cis-2-pentenenitrile

C

2-pentenenitrile
26294-98-4

2-pentenenitrile

D

3-Pentenenitrile
16529-66-1

3-Pentenenitrile

E

(Z)-2-methyl-2-butenenitrile
20068-02-4

(Z)-2-methyl-2-butenenitrile

F

tiglonitrile
30574-97-1

tiglonitrile

G

4-Pentenenitrile
592-51-8

4-Pentenenitrile

H

2-METHYL-3-BUTENENITRILE
16529-56-9

2-METHYL-3-BUTENENITRILE

I

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

J

(Z)-pent-2-enenitrile
16545-78-1

(Z)-pent-2-enenitrile

Conditions
ConditionsYield
C48H52O4P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite at 83.84℃; Product distribution / selectivity;
C44H44O6P2; nickel(0)(cyclooctadienyl)2-complex at 89.84℃; Product distribution / selectivity;
C44H44O6P2; nickel(0)(cyclooctadienyl)2-complex at 89.84℃; Product distribution / selectivity;
C48H52O4P2 at 83.84℃; Product distribution / selectivity;
(Z)-2-Butene
590-18-1

(Z)-2-Butene

hydrogen cyanide
74-90-8

hydrogen cyanide

buta-1,3-diene
106-99-0

buta-1,3-diene

A

cis-2-pentenenitrile
25899-50-7

cis-2-pentenenitrile

B

2-pentenenitrile
26294-98-4

2-pentenenitrile

C

3-Pentenenitrile
16529-66-1

3-Pentenenitrile

D

(Z)-2-methyl-2-butenenitrile
20068-02-4

(Z)-2-methyl-2-butenenitrile

E

tiglonitrile
30574-97-1

tiglonitrile

F

4-Pentenenitrile
592-51-8

4-Pentenenitrile

G

2-METHYL-3-BUTENENITRILE
16529-56-9

2-METHYL-3-BUTENENITRILE

H

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

I

4-ethenylcyclohexene
100-40-3

4-ethenylcyclohexene

J

(Z)-pent-2-enenitrile
16545-78-1

(Z)-pent-2-enenitrile

Conditions
ConditionsYield
Stage #1: (Z)-2-Butene; hydrogen cyanide; buta-1,3-diene; C44H44O6P2; (m-tolyl-O-)(p-tolyl-O-)2P; (m-tolyl-O-)2(p-tolyl-O-)P; tri-m-tolyl phosphite; tri-p-tolylphosphite at 99.84℃;
Stage #2: Lewis acid at 109.84℃; Product distribution / selectivity;
hydrogen cyanide
74-90-8

hydrogen cyanide

A

hexanedinitrile
111-69-3

hexanedinitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

Conditions
ConditionsYield
Stage #1: 3-pentenenitrile With zinc(II) chloride at 25 - 70℃; for 1.08333h;
Stage #2: hydrogen cyanide at 70℃; for 2.5h; Product distribution / selectivity;
Stage #1: 3-pentenenitrile With zinc(II) chloride; C42H40O4P2; Ni(cod)2 at 25 - 40℃; for 1.08333h;
Stage #2: hydrogen cyanide at 40℃; for 1.46667h; Product distribution / selectivity;
Stage #1: 3-pentenenitrile With zinc(II) chloride; C44H44O4P2; Ni(cod)2 at 25 - 40℃; for 1.08333h;
Stage #2: hydrogen cyanide at 40℃; for 1.33333h; Product distribution / selectivity;
Stage #1: 3-pentenenitrile With zinc(II) chloride; C46H48O4P2; Ni(cod)2 at 25 - 40℃; for 1.08333h;
Stage #2: hydrogen cyanide at 40℃; for 1.36667h; Product distribution / selectivity;
Stage #1: 3-pentenenitrile With zinc(II) chloride; C36H26O4P2; Ni(cod)2 at 25 - 70℃; for 1.08333h;
Stage #2: hydrogen cyanide at 70℃; for 1h; Product distribution / selectivity;
3-pentenenitrile
4635-87-4

3-pentenenitrile

2-hydroxy-2-methylpropanenitrile
75-86-5

2-hydroxy-2-methylpropanenitrile

A

hexanedinitrile
111-69-3

hexanedinitrile

B

2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

C

alpha-ethylsuccinonitrile
17611-82-4

alpha-ethylsuccinonitrile

Conditions
ConditionsYield
bis(1,5-cyclooctadiene)nickel (0); C68H92O6P2S; indium(III) trifluoroacetate at 70℃; for 3h; Conversion of starting material;
bis(1,5-cyclooctadiene)nickel (0); C56H68O12P2S; zinc(II) chloride at 70℃; for 3h; Conversion of starting material;
bis(1,5-cyclooctadiene)nickel (0); C68H68O8P2S; zinc(II) chloride at 70℃; for 3h; Conversion of starting material;
2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

2-methylglutaric acid
18069-17-5

2-methylglutaric acid

Conditions
ConditionsYield
With sulfuric acid; nitric acid at 90℃; for 16h; Reagent/catalyst; Temperature; Inert atmosphere;96%
With hydrogenchloride
acid hydrolysis;
With sulfuric acid; water at 105 - 125℃; for 8.42h; Inert atmosphere;
2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

4-cyanopentanoic acid
23886-52-4

4-cyanopentanoic acid

Conditions
ConditionsYield
With potassium phosphate buffer; nitrilase from Alcaligenes faecalis ATCC8750 at 30℃; for 96h; pH=7.3;91%
With glycerol for 72h; culture of Fusarium merismoides TG-1; Yield given;
With hydrogenchloride 1) microbial hydrolysis by Acidovorax facilis 72W, ATCC 55746; pH 7.0 (potassium phosphate buffer), 25 deg C, 21.5 h; 2) pH 2.5; Yield given. Multistep reaction;
2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

3-methylpiperidinehydrochloride
58531-29-6

3-methylpiperidinehydrochloride

Conditions
ConditionsYield
Stage #1: 2-methylglutaronitrile With C46H178O41Si42; titanium(IV)isopropoxide In toluene at 100℃; for 24h; Inert atmosphere;
Stage #2: With hydrogenchloride; water In toluene at 20℃; for 4h; Inert atmosphere; chemoselective reaction;
91%
2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

1,12-dodecanedioic acid
693-23-2

1,12-dodecanedioic acid

A

3-methyl-piperidine-2,6-dione
29553-51-3

3-methyl-piperidine-2,6-dione

B

1,12-dodecanedinitrile
4543-66-2

1,12-dodecanedinitrile

Conditions
ConditionsYield
With aluminum (III) chloride at 200℃; for 5h;A 88%
B 81%
2-methylglutaronitrile
4553-62-2

2-methylglutaronitrile

2-methylglutaronitrile-d3

2-methylglutaronitrile-d3

Conditions
ConditionsYield
With [carbonylchlorohydrido{bis[2-(diphenylphosphinomethyl)ethyl]amino}ethylamino] ruthenium(II); potassium tert-butylate; water-d2 at 70℃; for 24h; Inert atmosphere;86%

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