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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Content Natural Extract Harmane HACCP manufacturer

Cas:486-84-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Harmane

Cas:486-84-0

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 486-84-0 with best quality

Cas:486-84-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

Harmane

Cas:486-84-0

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price & quick delivery Appearance:Off-White Solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:Harman alkaloid l

9H-Pyrido[3,4-b]indole,1-methyl-

Cas:486-84-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

HARMANE

Cas:486-84-0

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Aribine~1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

HARMANE CAS 486-84-0

Cas:486-84-0

Min.Order:1 Metric Ton

FOB Price: $56.0 / 65.0

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

HARMANE

Cas:486-84-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

HARMANE

Cas:486-84-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

HARMANE

Cas:486-84-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

HARMANE

Cas:486-84-0

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

1-Methyl-9H-beta-carboline

Cas:486-84-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

HARMANE

Cas:486-84-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

shanghai Tauto Biotech Co., Ltd

The quality is guaranteed. If you find the product is wrong compared with COA, we promise 100% refund or change product. COA and HPLC will be shipped out with goods. You can also inform your analysis method and we will follow your analysis me

Harman

Cas:486-84-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Harmane 100mg

Cas:486-84-0

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

HarMan

Cas:486-84-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Chemsigma International Co.,Ltd.

bulk productiongoods in stockswe have the best competitive price in the marketmeantime,we are committed to service to our every customer Chemsigma International Co.,Ltd. is a chemical manufacturer, specialize in custom synthesis and organic chemical

HARMANE

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

1-Methyl-9H-pyrido[3,4-b]indole

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for

HARMANE

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

HARMANE Application:HARMANE

HARMANE

Cas:486-84-0

Min.Order:0

Negotiable

Type:Other

inquiry

Changchun Artel lmport and Export trade company

Supply top quality products with a reasonable price Application:api

486-84-0

Cas:486-84-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

HARMANE

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta

HARMANE

Cas:486-84-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds. Storage:

Harmane

Cas:486-84-0

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

tryptamine
61-54-1

tryptamine

acetaldehyde
75-07-0

acetaldehyde

harmane
486-84-0

harmane

Conditions
ConditionsYield
With acid88.7%
Stage #1: tryptamine; acetaldehyde With piperidine; methanesulfonic acid at 100℃; for 4h; Sealed tube;
Stage #2: With triethylamine In water
Stage #3: With palladium on activated charcoal at 180℃; for 5h; Reagent/catalyst; Temperature; Inert atmosphere;
80.2%
Yield given;
eleagnine
2506-10-7

eleagnine

harmane
486-84-0

harmane

Conditions
ConditionsYield
With C21H21ClIrNO2 In tetrahydrofuran; 2,2,2-trifluoroethanol for 20h; Inert atmosphere;93%
With [bis(acetoxy)iodo]benzene In N,N-dimethyl-formamide at 20℃; for 1h;84%
With 1,8-diazabicyclo[5.4.0]undec-7-ene; copper(ll) bromide In dimethyl sulfoxide at 25℃; for 24h; Green chemistry;81%
1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid
5470-37-1, 40678-46-4, 42438-72-2, 96149-76-7, 98718-62-8, 114497-71-1, 143396-05-8

1-methyl-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-3-carboxylic acid

harmane
486-84-0

harmane

Conditions
ConditionsYield
With tetrasodium cobalt(II) 4,4',4'',4'''-tetrasulphophthalocyanine In water; ethyl acetate at 20℃; for 24h; Irradiation; Green chemistry;87%
With ammonium persulfate; silver nitrate In water; acetonitrile at 80℃;56%
Multi-step reaction with 2 steps
1: acetic acid; water / 0.33 h / 100 °C
2: sodium hydroxide; sodium hydrogensulfite
View Scheme
With manganese(IV) oxide; sulfuric acid
(3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid
191279-37-5

(3S)-1-methyl-1,2,3,4-tetrahydro-β-carboline-3-carboxylic acid

harmane
486-84-0

harmane

Conditions
ConditionsYield
With copper dichloride In N,N-dimethyl-formamide at 130℃; for 1h;84%
With N-chloro-succinimide; triethylamine In N,N-dimethyl-formamide at 20℃; for 0.5h;82%
With iron(III) chloride In N,N-dimethyl-formamide at 130℃; for 1h; Catalytic behavior; Green chemistry;82%
1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole trifluoroacetate

1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole trifluoroacetate

harmane
486-84-0

harmane

Conditions
ConditionsYield
With 2 mol-% Pd/C; lithium carbonate In ethanol at 150℃; for 0.166667h; Sealed tube; Microwave irradiation;93%
With lithium carbonate; silver carbonate In N,N-dimethyl-formamide for 1h; Reflux;34%
1-methyl-4,9-dihydro-3H-β-carboline
525-41-7

1-methyl-4,9-dihydro-3H-β-carboline

harmane
486-84-0

harmane

Conditions
ConditionsYield
With potassium permanganate In acetone at 20℃;92%
With C21H21ClIrNO2 In tetrahydrofuran; 2,2,2-trifluoroethanol for 20h; Inert atmosphere;81%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dimethyl sulfoxide at 125℃; for 10h;76%
C14H15NO2

C14H15NO2

harmane
486-84-0

harmane

Conditions
ConditionsYield
With ammonium acetate In acetic acid; N,N-dimethyl-formamide at 120℃; for 7h;90 mg
C13H16N2O2

C13H16N2O2

harmane
486-84-0

harmane

Conditions
ConditionsYield
Stage #1: C13H16N2O2 With manganese(IV) oxide In water at 100℃; for 0.0833333h;
Stage #2: With sulfuric acid In water at 100℃; for 1h;
N-Acetyltryptamine
1016-47-3

N-Acetyltryptamine

harmane
486-84-0

harmane

Conditions
ConditionsYield
Stage #1: N-Acetyltryptamine With trifluoromethylsulfonic anhydride; Triphenylphosphine oxide In chlorobenzene at 20 - 130℃;
Stage #2: With manganese(IV) oxide In chlorobenzene at 130℃; for 4h;
82%
Stage #1: N-Acetyltryptamine With trifluoromethylsulfonic anhydride; Triphenylphosphine oxide In chlorobenzene
Stage #2: With manganese(IV) oxide In chlorobenzene
80%
With trichlorophosphate In toluene; acetonitrile for 3h; Reflux;
1-methyl-2-tosyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole
5159-20-6

1-methyl-2-tosyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole

harmane
486-84-0

harmane

Conditions
ConditionsYield
With oxygen; sodium hydroxide In water; dimethyl sulfoxide at 125℃; for 5h;82%
Stage #1: 1-methyl-2-tosyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole In tetrahydrofuran at -78℃; for 2h;
Stage #2: With oxygen In tetrahydrofuran at 20℃;
74%
1-methyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-b]indole
31965-09-0

1-methyl-6,7,8,9-tetrahydro-5H-pyrido[3,4-b]indole

harmane
486-84-0

harmane

Conditions
ConditionsYield
With palladium on activated carbon In diphenylether at 210℃; for 0.66h; Inert atmosphere;91%
With palladium on activated charcoal; diphenylether; biphenyl
(+/-)-Calligonine hydrochloride
6678-82-6

(+/-)-Calligonine hydrochloride

harmane
486-84-0

harmane

Conditions
ConditionsYield
With 5 mol% Pd/C; lithium carbonate In ethanol at 150℃; for 0.1h; Sealed tube; Microwave irradiation;92%
6-bromo-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

6-bromo-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

harmane
486-84-0

harmane

Conditions
ConditionsYield
With 5 mol% Pd/C; lithium carbonate In ethanol at 150℃; for 0.75h; Sealed tube; Microwave irradiation;75%
3-azido-2-methyl-4-phenylpyridine

3-azido-2-methyl-4-phenylpyridine

harmane
486-84-0

harmane

Conditions
ConditionsYield
In 5,5-dimethyl-1,3-cyclohexadiene for 10h; Reflux;45%
tert.-butylhydroperoxide
75-91-2

tert.-butylhydroperoxide

betacarboline
244-63-3

betacarboline

harmane
486-84-0

harmane

Conditions
ConditionsYield
With iron(II) sulfate In sulfuric acid; water; acetic acid at 0℃; for 2h;75%
6-chloro-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

6-chloro-1-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole hydrochloride

harmane
486-84-0

harmane

Conditions
ConditionsYield
With 5 mol% Pd/C; lithium carbonate In ethanol at 150℃; for 0.1h; Sealed tube; Microwave irradiation;60%
N,N-dimethyl acetamide
127-19-5

N,N-dimethyl acetamide

1-(phenylsulfonyl)-3-vinyl-1H-indole
82980-12-9

1-(phenylsulfonyl)-3-vinyl-1H-indole

harmane
486-84-0

harmane

Conditions
ConditionsYield
Stage #1: 3-ethenyl-1-phenylsulfonyl-1H-indole With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl acetamide In tetrahydrofuran at -78 - -10℃;
Stage #3: With hydroxylamine hydrochloride; sodium acetate In 1,2-dichloro-benzene for 8h; Heating;
46%
N,N-dimethyl acetamide
127-19-5

N,N-dimethyl acetamide

(E)-1-(Phenylsulfonyl)-3-(β-methoxyvinyl)indole
110128-40-0

(E)-1-(Phenylsulfonyl)-3-(β-methoxyvinyl)indole

harmane
486-84-0

harmane

Conditions
ConditionsYield
Stage #1: (E)-1-(Phenylsulfonyl)-3-(β-methoxyvinyl)indole With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl acetamide In tetrahydrofuran at -78 - -10℃;
Stage #3: With hydroxylamine hydrochloride; sodium acetate In 1,2-dichloro-benzene for 8h; Heating;
53%
N,N-dimethyl acetamide
127-19-5

N,N-dimethyl acetamide

(E)-3-(2-nitrovinyl)-1-(phenylsulfonyl)-1H-indole
211738-25-9

(E)-3-(2-nitrovinyl)-1-(phenylsulfonyl)-1H-indole

harmane
486-84-0

harmane

Conditions
ConditionsYield
Stage #1: (E)-3-(2-nitrovinyl)-1-(phenylsulfonyl)-1H-indole With lithium diisopropyl amide In tetrahydrofuran at -78℃; for 1h;
Stage #2: N,N-dimethyl acetamide In tetrahydrofuran at -78 - -10℃;
Stage #3: With hydroxylamine hydrochloride; sodium acetate In 1,2-dichloro-benzene for 8h; Heating;
45%
L-Tryptophan
73-22-3

L-Tryptophan

harmane
486-84-0

harmane

Conditions
ConditionsYield
With sulfuric acid; acetaldehyde Oxydieren der Reaktionsloesung mit Kaliumdichromat;
With acetic anhydride; zinc(II) chloride Oxydieren des entstandenen Oels mit Chromschwefelsaeure;
Multi-step reaction with 2 steps
1: acetic acid / 3 h / Reflux
2: acetic acid; potassium dichromate / water / 0.33 h / 100 °C
View Scheme
2,2-dimethyl-N-(2-(3-fluoro-2-methyl-4-pyridyl)phenyl)propanamide

2,2-dimethyl-N-(2-(3-fluoro-2-methyl-4-pyridyl)phenyl)propanamide

harmane
486-84-0

harmane

Conditions
ConditionsYield
With pyridine hydrochloride at 210℃; for 0.25h;84%
tryptamine
61-54-1

tryptamine

harmane
486-84-0

harmane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sulfuric acid / water / 0.5 h / 20 °C
1.2: 7 h / Reflux
2.1: maleic acid; palladium on activated charcoal / water / 8 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: sulfuric acid / water / 7 h / Reflux
2: maleic acid; palladium on activated charcoal / water / 8 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: 1,2-dichloro-ethane / 0.05 h / 110 °C / Sealed tube; Microwave irradiation
2: lithium carbonate; 2 mol-% Pd/C / ethanol / 0.17 h / 150 °C / Sealed tube; Microwave irradiation
View Scheme
harman-3-carboxylic acid
22329-38-0

harman-3-carboxylic acid

harmane
486-84-0

harmane

Conditions
ConditionsYield
With copper In quinoline at 240℃; for 1h;
With sodium hydrogensulfite; sodium hydroxide
C15H15N3O

C15H15N3O

A

harmane
486-84-0

harmane

B

C14H16N2O

C14H16N2O

Conditions
ConditionsYield
With sodium cyanoborohydride In tetrahydrofuran; methanol at 65℃; Inert atmosphere;A n/a
B 20%
trimethylaluminum
75-24-1

trimethylaluminum

1-Chlor-9H-pyrido<3,4-b>indol
102337-43-9

1-Chlor-9H-pyrido<3,4-b>indol

harmane
486-84-0

harmane

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; hexane for 3h; Heating;66%
methyl 5-acetyl-4-[(β-carbolin-1-yl)methyl]-1,4-dihydropyridine-3-carboxylate
668987-16-4

methyl 5-acetyl-4-[(β-carbolin-1-yl)methyl]-1,4-dihydropyridine-3-carboxylate

A

harmane
486-84-0

harmane

B

5-(1'-hydroxyethyl) nicotinic acid methyl ester
38940-64-6

5-(1'-hydroxyethyl) nicotinic acid methyl ester

C

methyl 4-[(β-carbolin-1-yl)methyl]-5-(1-hydroxyethyl)-1,4-dihydropyridine-3-carboxylate
52811-49-1

methyl 4-[(β-carbolin-1-yl)methyl]-5-(1-hydroxyethyl)-1,4-dihydropyridine-3-carboxylate

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 20℃; for 0.25h;
1-(phenylsulfonyl)indole-3-carbaldehyde
80360-20-9

1-(phenylsulfonyl)indole-3-carbaldehyde

harmane
486-84-0

harmane

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: 63 percent / AcONa; AcOH
2.1: LDA / tetrahydrofuran / 1 h / -78 °C
2.2: tetrahydrofuran / -78 - -10 °C
2.3: 45 percent / NH2OH*HCl; AcONa / 1,2-dichloro-benzene / 8 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: 65 percent / t-BuOK / tetrahydrofuran
2.1: LDA / tetrahydrofuran / 1 h / -78 °C
2.2: tetrahydrofuran / -78 - -10 °C
2.3: 46 percent / NH2OH*HCl; AcONa / 1,2-dichloro-benzene / 8 h / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: 77 percent / t-BuOK / tetrahydrofuran
2.1: LDA / tetrahydrofuran / 1 h / -78 °C
2.2: tetrahydrofuran / -78 - -10 °C
2.3: 53 percent / NH2OH*HCl; AcONa / 1,2-dichloro-benzene / 8 h / Heating
View Scheme
acetaldehyde
75-07-0

acetaldehyde

L-Tryptophan
73-22-3

L-Tryptophan

harmane
486-84-0

harmane

Conditions
ConditionsYield
With hydrogenchloride; iron(III) chloride In N,N-dimethyl-formamide at 130℃; for 1h; Catalytic behavior; Pictet-Spengler Synthesis; Green chemistry;78%
Stage #1: acetaldehyde; L-Tryptophan Acidic conditions;
Stage #2: With potassium dichromate
With potassium dichromate
Harman-2-oxide
2506-09-4

Harman-2-oxide

harmane
486-84-0

harmane

Conditions
ConditionsYield
With acetic acid; zinc for 2h; Reduction;87%

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