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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

4-Chloro-2-methylthiopyrimidine Manufacturer/High quality/Best price/In stock

Cas:49844-90-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Pyrimidine, 4-Chloro-2-(Methylthio)- supplier in China

Cas:49844-90-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Pyrimidine, 4-Chloro-2-(Methylthio)-

Cas:49844-90-8

Min.Order:1

Negotiable

Type:Other

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chloro-2-(methylthio)-pyrimidine

Cas:49844-90-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

high quality 4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

4-Chloro-2-(methylthio)pyrimidine

Cas:49844-90-8

Min.Order:1 Kilogram

FOB Price: $100.0 / 150.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 49844-90-8 with best quality

Cas:49844-90-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name: 2-methylthio-4-chloropyrimine CAS NO. 49844-90-8 Structural formula: Appearance: colorless liquid Assay: 98% Mo

4-Chloro-2-methylthiopyrimidine CAS: 49844-90-8

Cas:49844-90-8

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry plac

4-Chloro-2-methylthiopyrimidine CAS No.49844-90-8

Cas:49844-90-8

Min.Order:100 Gram

Negotiable

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pyrimidine,4-chloro-2-(methylthio)- 49844-90-8

Cas:49844-90-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

4-Chloro-2-methylthiopyrimidine CAS:49844-90-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality

4-Chloro-2-methylthiopyrimidine CAS:49844-90-8

Cas:49844-90-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pyrimidine,4-chloro-2-(methylthio)-

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Pyrimidine, 4-Chloro-2-(Methylthio)-

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Chloro-2-(methylmercapto)pyrimidine

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

4-chloro-2-(methylsulfanyl)pyrimidine

Cas:49844-90-8

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

CAS:49844-90-8

Cas:49844-90-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-Chloro-2-methylthiopyrimidine≥ 99% (GC)

Cas:49844-90-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhu Nuowei Chemistry Technologies Co., Ltd.

Wuhu Nuovo Chemical Technology Co., Ltd. was established in August 2014, mainly engaged in the development, production and sales of ionic liquids, ribose, nucleosides, nucleotides and related chemicals; Products are mainly used in new energy, new ma

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:100 Gram

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Finebiotech Co.,Ltd.

Shanghai Finebiotech Co.,Ltd.was established in 2020, which providing professional chemical services. As a customer-oriented company, we have distinguished ourself from others in providing worldwide customers with cost-effective and efficient service

4-chloro-2-(methylsulfanyl)pyrimidine

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-Chloro-2-methylthiopyrimidine cas no. 49844-90-8 98%

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Suzhou Sibian Chemical Technology Co., Ltd

The process is mature and can be mass produced to 100 kg, with good quality and purity up to 99%.The product has a large stock and can be supplied stably. Package:bottle Application:Drug R&D Transportation:Sealed drying(25℃) Port:ShangHai

4-Chloro-2-methylthiopyrimidine

Cas:49844-90-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Chloro-2-(methylthio)pyrimidine

Cas:49844-90-8

Min.Order:0

Negotiable

Type:Other

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

High Purity Pyrimidine, 4-Chloro-2-(Methylthio)- 49844-90-8

Cas:49844-90-8

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

Synthetic route

2-(methylsulfanyl)pyrimidin-4-ol
5751-20-2

2-(methylsulfanyl)pyrimidin-4-ol

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

Conditions
ConditionsYield
Stage #1: 2-(methylsulfanyl)pyrimidin-4-ol With trichlorophosphate In N,N-dimethyl-formamide; toluene at 20℃; for 0.5h;
Stage #2: With thionyl chloride In N,N-dimethyl-formamide; toluene at 20 - 80℃; for 1h; Time; Solvent; Reagent/catalyst;
88.3%
With trichlorophosphate at 80℃;
With trichlorophosphate In neat (no solvent) at 80℃; for 7h; Inert atmosphere;
2-Methylthiouracil
5751-20-2

2-Methylthiouracil

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

Conditions
ConditionsYield
With thionyl chloride In dichloromethane; N,N-dimethyl-formamide at 40℃; for 3h;87.6%
With thionyl chloride; N,N-dimethyl-formamide In dichloromethane at 40℃; for 3h;87.6%
With trichlorophosphate
With trichlorophosphate
2-methylthio-1H-pyrimidin-4-one
5751-20-2

2-methylthio-1H-pyrimidin-4-one

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

Conditions
ConditionsYield
With trichlorophosphate 1) reflux, 1.75 h, 2) r.t., overnight;
4-oxy-2-methylsulfanyl-pyrimidine hydrochloride

4-oxy-2-methylsulfanyl-pyrimidine hydrochloride

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

Conditions
ConditionsYield
With phosphorus pentachloride; trichlorophosphate
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-chloro-2-methanesulfonylpyrimidine
97229-11-3

4-chloro-2-methanesulfonylpyrimidine

Conditions
ConditionsYield
With hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide In ethanol; water at 0℃; for 24h; Inert atmosphere;99%
With chromium(VI) oxide; periodic acid In ethyl acetate; acetonitrile at 0℃; for 1.75h;94%
With hexaammonium heptamolybdate tetrahydrate; dihydrogen peroxide In ethanol at 0 - 20℃; Inert atmosphere;85.7%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-iodo-2-(methylthio)pyrimidine
1122-74-3

4-iodo-2-(methylthio)pyrimidine

Conditions
ConditionsYield
With hydrogen iodide In water at 20℃; for 8h;99%
With hydrogen iodide In water at 20℃; for 16h;98%
With hydrogen iodide In water at 20℃; for 72h;95%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

2,6-dimethylbenzene boronic acid
100379-00-8

2,6-dimethylbenzene boronic acid

4-(2,6-dimethylphenyl)-2-(methylthio)pyrimidine

4-(2,6-dimethylphenyl)-2-(methylthio)pyrimidine

Conditions
ConditionsYield
With potassium carbonate; bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) In water; toluene for 12h; Suzuki-Miyaura cross-coupling; Heating;99%
With potassium carbonate; PdCl2[P(tBu)2(p-Me2NC6H4)]2 In water; toluene at 100℃; Suzuki-Miyaura cross-coupling;99%
benzoimidazole
51-17-2

benzoimidazole

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

1-(2-(methylthio)pyrimidin-4-yl)-1H-benzo[d]imidazole

1-(2-(methylthio)pyrimidin-4-yl)-1H-benzo[d]imidazole

Conditions
ConditionsYield
With triethylamine In neat (no solvent) at 80℃; for 0.166667h; Microwave irradiation; Green chemistry;99%
With NaH In N,N-dimethyl-formamide
With NaH In N,N-dimethyl-formamide
With triethylamine In N,N-dimethyl-formamide at 60 - 120℃; Microwave irradiation;
1,2,3-Benzotriazole
95-14-7

1,2,3-Benzotriazole

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

C11H9N5S*ClH

C11H9N5S*ClH

Conditions
ConditionsYield
In neat (no solvent) at 80℃; for 0.0833333h; Microwave irradiation; Green chemistry;99%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

2-cyclobutyl-4-(methylsulfonyl)aniline

2-cyclobutyl-4-(methylsulfonyl)aniline

N-(2-cyclobutyl-4-(methylsulfonyl)phenyl)-2-(methylthio)pyrimidin-4-amine

N-(2-cyclobutyl-4-(methylsulfonyl)phenyl)-2-(methylthio)pyrimidin-4-amine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In isopropyl alcohol at 70℃; for 22.6667h; Inert atmosphere;99%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-Phenylimidazole
670-95-1

4-Phenylimidazole

C14H12N4S
1244039-66-4

C14H12N4S

Conditions
ConditionsYield
Stage #1: 4-Phenylimidazole With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 1.16667h;
Stage #2: 4-Chloro-2-methylthiopyrimidine In N,N-dimethyl-formamide; mineral oil at 0℃; for 0.5h;
98.4%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

1-(2-hydroxybenzyl)-3-(3-t-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea
940875-00-3

1-(2-hydroxybenzyl)-3-(3-t-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea

1-(2-(2-(methylthio)pyrimidin-4-yloxy)benzyl)-3-(3-t-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea
940870-62-2

1-(2-(2-(methylthio)pyrimidin-4-yloxy)benzyl)-3-(3-t-butyl-1-p-tolyl-1H-pyrazol-5-yl)urea

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 22h;98%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-azido-2-(methylthio)pyrimidine

4-azido-2-(methylthio)pyrimidine

Conditions
ConditionsYield
With sodium azide In N,N-dimethyl-formamide at 20℃; for 72h;98%
With sodium azide In N,N-dimethyl-formamide
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

5-nitroindole
6146-52-7

5-nitroindole

1-(2-(methylthio)pyrimidin-4-yl)-5-nitro-1H-indole

1-(2-(methylthio)pyrimidin-4-yl)-5-nitro-1H-indole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 80℃;98%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

5-chloro-2-methoxyphenyl boronic acid
89694-48-4

5-chloro-2-methoxyphenyl boronic acid

4-(5-chloro-2-methoxyphenyl)-2-methylsulfanylpyrimidine
1262148-80-0

4-(5-chloro-2-methoxyphenyl)-2-methylsulfanylpyrimidine

Conditions
ConditionsYield
With potassium carbonate; tetrakis(triphenylphosphine) palladium(0) In ethanol; toluene for 1h; Suzuki Coupling; Reflux;97%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-bromo-2-methylsulfanylpyrimidine
959236-97-6

4-bromo-2-methylsulfanylpyrimidine

Conditions
ConditionsYield
With trimethylsilyl bromide In acetonitrile at 40℃; for 30h;96%
With trimethylsilyl bromide In acetonitrile at 40℃; for 24h; Inert atmosphere;96%
With trimethylsilyl bromide In acetonitrile at 40℃; for 24h; Inert atmosphere;95%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

phenylpropyolic acid
637-44-5

phenylpropyolic acid

C13H10N2S

C13H10N2S

Conditions
ConditionsYield
With bis[dicyclohexyl(2,4,6-triisopropyl-[1,1':3',1''-terphenyl]-2-yl)phosphane]palladium(II) dichloride; caesium carbonate In tetrahydrofuran at 80℃; for 7h;96%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-chloro-2-(methylsulfinyl)pyrimidine
97229-10-2

4-chloro-2-(methylsulfinyl)pyrimidine

Conditions
ConditionsYield
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 24h;95%
With manganese(II) triflate; 1-Adamantanecarboxylic acid; C32H38N4O2; dihydrogen peroxide In acetonitrile at -30℃; for 0.5h; enantioselective reaction;85%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 25℃; Cooling with ice;
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-methoxyphenylboronic acid
5720-07-0

4-methoxyphenylboronic acid

4-(4-methoxyphenyl)-2-(methylsulfanyl)pyrimidine
148990-17-4

4-(4-methoxyphenyl)-2-(methylsulfanyl)pyrimidine

Conditions
ConditionsYield
With potassium carbonate; bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) In water; toluene for 12h; Suzuki-Miyaura cross-coupling; Heating;95%
With potassium carbonate; PdCl2[P(tBu)2(p-Me2NC6H4)]2 In water; toluene at 100℃; Suzuki-Miyaura cross-coupling;95%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

3,4-dinitophenol
577-71-9

3,4-dinitophenol

4-(3,4-dinitro-phenoxy)-2-methylsulfanyl-pyrimidine
952490-61-8

4-(3,4-dinitro-phenoxy)-2-methylsulfanyl-pyrimidine

Conditions
ConditionsYield
at 150℃; for 2h;95%
at 150℃; for 2h;
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

2,3,4-trimethoxyphenylboronic acid
118062-05-8

2,3,4-trimethoxyphenylboronic acid

C14H16N2O3S
634611-62-4

C14H16N2O3S

Conditions
ConditionsYield
Stage #1: 4-Chloro-2-methylthiopyrimidine; 2,3,4-trimethoxyphenylboronic acid With sodium carbonate In 1,4-dioxane; water at 20℃; for 0.0833333h;
Stage #2: tetrakis(triphenylphosphine) palladium(0) In 1,4-dioxane; water at 110℃; for 16h;
95%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

phenylacetylene
536-74-3

phenylacetylene

C13H10N2S

C13H10N2S

Conditions
ConditionsYield
With potassium phosphate; bis[dicyclohexyl(2,4,6-triisopropyl-[1,1':3',1''-terphenyl]-2-yl)phosphane]palladium(II) dichloride In acetonitrile at 90℃; for 6h; Sonogashira Cross-Coupling;95%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

3‐cyclopropyl‐2‐propynoic acid
7358-93-2

3‐cyclopropyl‐2‐propynoic acid

C10H10N2S

C10H10N2S

Conditions
ConditionsYield
With bis[dicyclohexyl(2,4,6-triisopropyl-[1,1':3',1''-terphenyl]-2-yl)phosphane]palladium(II) dichloride; caesium carbonate In tetrahydrofuran at 80℃; for 5h;95%
tetrahydropyran-4-carboxylic acid methyl ester
110238-91-0

tetrahydropyran-4-carboxylic acid methyl ester

4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

methyl 4-(2-(methylthio)pyrimidin-4-yl)tetrahydro-2H-pyran-4-carboxylate

methyl 4-(2-(methylthio)pyrimidin-4-yl)tetrahydro-2H-pyran-4-carboxylate

Conditions
ConditionsYield
With lithium hexamethyldisilazane In tetrahydrofuran at 30℃; for 0.0833333h;95%
With lithium hexamethyldisilazane In tetrahydrofuran at 30℃; for 0.0833333h;95%
With lithium hexamethyldisilazane In tetrahydrofuran at 30℃; for 0.0833333h;95%
With lithium hexamethyldisilazane In tetrahydrofuran at 30℃; for 0.0833333h;95%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

trimethylamine
75-50-3

trimethylamine

Trimethyl-4-(2-methylthiopyrimidinyl)ammoniumchlorid
6622-64-6

Trimethyl-4-(2-methylthiopyrimidinyl)ammoniumchlorid

Conditions
ConditionsYield
In benzene 1) 0 deg C; 2) room temperature, 1h;94%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-cyanophenylboronic acid
126747-14-6

4-cyanophenylboronic acid

4-(2-methylsulfanylpyrimidin-4-yl)benzonitrile
874778-91-3

4-(2-methylsulfanylpyrimidin-4-yl)benzonitrile

Conditions
ConditionsYield
With potassium carbonate; bis(di-tert-butyl(4-dimethylaminophenyl)phosphine)dichloropalladium(II) In water; toluene for 12h; Suzuki-Miyaura cross-coupling; Heating;94%
With potassium carbonate; PdCl2[P(tBu)2(p-Me2NC6H4)]2 In water; toluene at 100℃; Suzuki-Miyaura cross-coupling;94%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

phenol
108-95-2

phenol

A

2-methylthio-4-phenoxypyrimidine

2-methylthio-4-phenoxypyrimidine

B

(E)-methyl 2-[2-(4-phenoxypyrimidin-2-yloxy)phenyl]-3-methoxypropenoate
131860-90-7

(E)-methyl 2-[2-(4-phenoxypyrimidin-2-yloxy)phenyl]-3-methoxypropenoate

Conditions
ConditionsYield
In N,N-dimethyl-formamideA 94%
B n/a
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-nitro-phenol
100-02-7

4-nitro-phenol

2-methylsulfanyl-4-(4-nitrophenoxy)-pyrimidine
307309-31-5

2-methylsulfanyl-4-(4-nitrophenoxy)-pyrimidine

Conditions
ConditionsYield
Stage #1: 4-nitro-phenol With sodium hydride at 0℃; for 0.5h;
Stage #2: 4-Chloro-2-methylthiopyrimidine at 70 - 80℃; for 16h;
94%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

4-aminoindazole
41748-71-4

4-aminoindazole

N-(2-methylsulfanylpyrimidin-4-yl)-1H-indazol-4-amine
945396-85-0

N-(2-methylsulfanylpyrimidin-4-yl)-1H-indazol-4-amine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane; butan-1-ol at 80℃; for 4h;93%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

2-ethoxy-4-fluorobenzenamine
178993-28-7

2-ethoxy-4-fluorobenzenamine

N-(2-ethoxy-4-fluorophenyl)-2-(methylthio)pyrimidin-4-amine

N-(2-ethoxy-4-fluorophenyl)-2-(methylthio)pyrimidin-4-amine

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol at 80℃; for 4h;93%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

tri-n-butyl(vinyl)tin
7486-35-3

tri-n-butyl(vinyl)tin

2-methylthio-4-vinylpyrimidine
131467-05-5

2-methylthio-4-vinylpyrimidine

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In 1,2-dichloro-ethane at 70℃; for 48h;92%
With tetrakis(triphenylphosphine) palladium(0) In 1,2-dichloro-ethane at 70℃; for 48h; Stille Cross Coupling;92%
With tetrakis(triphenylphosphine) palladium(0) In 1,2-dichloro-ethane at 70℃; for 48h; Stille Cross Coupling;92%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

(2-fluoro-pyridin-3-yl)boronic acid
174669-73-9

(2-fluoro-pyridin-3-yl)boronic acid

4-(2-fluoropyridin-3-yl)-2-(methylthio)pyrimidine

4-(2-fluoropyridin-3-yl)-2-(methylthio)pyrimidine

Conditions
ConditionsYield
With potassium hydrogencarbonate; PdCl2[P(tBu)2(p-Me2NC6H4)]2 In water; acetonitrile at 100℃; Suzuki-Miyaura cross-coupling;92%
With tetrakis(triphenylphosphine) palladium(0); sodium carbonate In 1,4-dioxane; water at 100℃; Inert atmosphere;73%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

5-methoxy-1H-indazole
94444-96-9

5-methoxy-1H-indazole

5-methoxy-1-(2-(methylthio)pyrimidin-4-yl)-1H-indazole

5-methoxy-1-(2-(methylthio)pyrimidin-4-yl)-1H-indazole

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide at 0℃; for 2h; Inert atmosphere;92%
4-Chloro-2-methylthiopyrimidine
49844-90-8

4-Chloro-2-methylthiopyrimidine

tert-butyl 4-(4-(((tert-butyldimethylsilyl)oxy)-methyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate

tert-butyl 4-(4-(((tert-butyldimethylsilyl)oxy)-methyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate

tert-butyl 4-(4-(((tert-butyldimethylsilyl)oxy)-methyl)-5-(2-(methylthio)pyrimidin-4-yl)-1H-1,2,3-triazol-1-yl)-piperidine-1-carboxylate

tert-butyl 4-(4-(((tert-butyldimethylsilyl)oxy)-methyl)-5-(2-(methylthio)pyrimidin-4-yl)-1H-1,2,3-triazol-1-yl)-piperidine-1-carboxylate

Conditions
ConditionsYield
Stage #1: tert-butyl 4-(4-(((tert-butyldimethylsilyl)oxy)-methyl)-1H-1,2,3-triazol-1-yl)piperidine-1-carboxylate With n-butyllithium In tetrahydrofuran; hexane Cooling with acetone-dry ice;
Stage #2: With zinc(II) chloride In tetrahydrofuran; hexane Cooling with acetone-dry ice;
Stage #3: 4-Chloro-2-methylthiopyrimidine With (2‑dicyclohexylphosphino‑2′,6′‑dimethoxybiphenyl)[2‑(2′‑amino‑1,1′‑biphenyl)]palladium(II) methanesulfonate In tetrahydrofuran; hexane at 60℃; for 18h; Cooling with acetone-dry ice;
92%

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