As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryProduct Description Product website: http://www.finerchem.com Product Name Aminopyrazine CAS No. 5049-61-6
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryColorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquirychengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
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inquiryAbout Product Details
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inquiryAminopyrazine Basic information Product Name: Aminopyrazine Synonyms: AMINOPYRAZINE;2-AMINOPYRAZINE;APZ;TIMTEC-BB SBB004388;NSC 13147;PYRAZIN-2-AMINE;PYRAZINAMINE;P
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiryCAS NO:5049-61-6 Appearance: White Powder Storagr:Keep in a cool and dry place Usage:Use for parmaceutical intermediates or chemical reaserch Appearance: white powder Storage:Store in cool and dry place, away from sun light. Package: 25K
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryProduct Name: Aminopyrazine CAS: 5049-61-6 MF: C4H5N3 MW: 95.1 EINECS: 225-748-7 Aminopyrazine Structure Aminopyrazine Chemical Properties Melting point 118-120 °C (lit.) Boiling point 167.6°C (rough estimate) density
Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
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inquiryAminopyrazine CAS: 5049-61-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie
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inquiry1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia
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Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
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inquiryPacking: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd
2-iodopyrazine
2-Aminopyrazine
Conditions | Yield |
---|---|
With copper(I) oxide; ammonia; potassium carbonate In 1,4-dioxane at 140℃; under 7757.43 Torr; for 16h; | 92% |
With copper(I) oxide; ammonium hydroxide; potassium carbonate at 140℃; for 16h; Inert atmosphere; | 49% |
2-amino-3,5-dibromopyrazine
A
2-Aminopyrazine
B
5-amino-2-bromopyrazine
Conditions | Yield |
---|---|
With palladium diacetate; 1,8-diazabicyclo[5.4.0]undec-7-ene; triphenylphosphine In dimethyl sulfoxide regioselective reaction; | A 10% B 87% |
2-pyrazine carbonitrile
2-Aminopyrazine
Conditions | Yield |
---|---|
With sodium hypochlorite; sodium hydroxide at 20 - 60℃; for 5h; | 82.6% |
With sodium hypochlorite; potassium hydroxide; sodium hydroxide at 40℃; for 2h; pH=8; Temperature; | |
With sodium hypochlorite; water; sodium hydroxide at -5 - 100℃; | 74 g |
Conditions | Yield |
---|---|
With C46H71Cl3N2Pd; ammonia; sodium t-butanolate In 1,4-dioxane at 100℃; for 16h; Inert atmosphere; Schlenk technique; | A 79% B n/a |
2-chloropyrazin
2-Aminopyrazine
Conditions | Yield |
---|---|
With dicyclohexyl(2',4',6'-triisopropyl-5-methoxy-3,4,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; C50H70NO4PPdS; C50H70NO4PPdS; dicyclohexyl(2',4',6'-triisopropyl-4-methoxy-3,5,6-trimethyl-[1,1'-biphenyl]-2-yl)phosphine; ammonia; sodium t-butanolate In 1,4-dioxane at 50℃; for 24h; Inert atmosphere; | 75% |
With ammonia; water at 200℃; | |
With ammonia In dimethyl sulfoxide at 130℃; |
phthalimide
A
2-Aminopyrazine
B
2-(5-Amino-pyrazin-2-ylmethyl)-isoindole-1,3-dione
Conditions | Yield |
---|---|
With sodium carbonate In CH2Cl2/MeOH; dichloromethane; trifluoroacetic acid | A n/a B 73% |
Conditions | Yield |
---|---|
With potassium permanganate; potassium amide In ammonia for 0.166667h; | 65% |
Conditions | Yield |
---|---|
With acetamidine hydrochloride; sodium hydroxide In water; dimethyl sulfoxide at 130℃; for 24h; Schlenk technique; chemoselective reaction; | 52% |
2-(1-hydroxyethyl)pyrazine
2-Aminopyrazine
Conditions | Yield |
---|---|
With sodium azide; methanesulfonic acid; trifluoroacetic acid In hexane at 40℃; for 12h; | 45% |
Conditions | Yield |
---|---|
With [bis(acetoxy)iodo]benzene; toluene-4-sulfonic acid In 1,2-dichloro-ethane at 20℃; for 1h; Schlenk technique; chemoselective reaction; | A n/a B 28% |
N-(3',5'-dibromopyrazin-2'-yl)pyridinium aminide
A
2-Aminopyrazine
Conditions | Yield |
---|---|
With 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; potassium carbonate In acetonitrile; benzene at 80℃; for 24h; | A 20% B 24% |
N-(3',5'-dibromopyrazin-2'-yl)pyridinium aminide
benzene
A
2-Aminopyrazine
Conditions | Yield |
---|---|
With 2,2'-azobis(isobutyronitrile); tris-(trimethylsilyl)silane; potassium carbonate In acetonitrile at 80℃; for 24h; | A 20% B 24% C 20% |
Conditions | Yield |
---|---|
With sodium hypochlorite Behandeln des erhaltenen Natrium-Salzes der Pyrazinylcarbamidsaeure C5H5N3O2(Kristalle;Verfaerbung ab 257grad)mit wss.Saeuren.; |
Conditions | Yield |
---|---|
With diethylene glycol monoethyl ether acetate at 210 - 245℃; | |
With nitrobenzene | |
Erhitzen ueber den Schmelzpunkt; |
Conditions | Yield |
---|---|
With sulfuric acid at 240 - 245℃; |
Conditions | Yield |
---|---|
With sodium hydroxide; trichlorophosphate 1) 70 deg C, 2 h; Yield given. Multistep reaction. Yields of byproduct given; |
N-(Tetrazolyl-5')-2-pyrazinylamine
A
2-Aminopyrazine
B
[1,2,4] triazolo[1,5-a]pyrazin-2-amine
Conditions | Yield |
---|---|
With PPA at 290℃; |
9-tert-butylfluorene
A
2-Aminopyrazine
B
potassium salt of 9-tert-butylfluorene
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 24.9℃; Equilibrium constant; |
Conditions | Yield |
---|---|
With polystyrene Wang resin; diphenylphosphoranyl azide; triethylamine; trifluoroacetic acid 1.) toluene, 100 deg C, 16 h, 2.) CH2Cl2, 5 min; Yield given; Multistep reaction; |
Conditions | Yield |
---|---|
at 240 - 245℃; |
2-Aminopyrazine
Conditions | Yield |
---|---|
beim Erhitzen ueber den Schmelzpunkt; |
Conditions | Yield |
---|---|
at 70℃; | 100% |
With sodium hydrogencarbonate at 100℃; for 48h; Inert atmosphere; | 50% |
With sodium hydrogencarbonate at 100℃; for 48h; | 50% |
2-Aminopyrazine
phenylglyoxal hydrate
2-phenylimidazo<1,2-a>pyrazin-3(7H)-one
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane for 168h; | 100% |
With hydrogenchloride In ethanol at 20 - 25℃; for 18h; | 49% |
With hydrogenchloride In ethanol; water at 20℃; for 15h; Cyclization; | 20% |
2-Aminopyrazine
4-chlorophenylglyoxal
2-(4-Chloro-phenyl)-7H-imidazo[1,2-a]pyrazin-3-one
Conditions | Yield |
---|---|
With boron trifluoride diethyl etherate In dichloromethane for 264h; | 100% |
Conditions | Yield |
---|---|
In toluene for 2.25h; Heating / reflux; | 100% |
2-Aminopyrazine
methyl (2S,4R)-N-(tert-butyloxy)carbonyl-4-fluoropyrrolidine-2-carboxylate
(2S,4R)-1-(4-(3-cyclopropyl-1H-pyrazol-5-ylamino)-6-morpholino-1,3,5-triazin-2-yl)-4-fluoro-N-(pyrazin-2-yl)pyrrolidine-2-carboxamide
Conditions | Yield |
---|---|
Stage #1: 2-Aminopyrazine With isopropylmagnesium chloride In tetrahydrofuran at 0 - 20℃; Stage #2: methyl (2S,4R)-N-(tert-butyloxy)carbonyl-4-fluoropyrrolidine-2-carboxylate In tetrahydrofuran at 20℃; for 4h; | 100% |
Conditions | Yield |
---|---|
In ethanol at 25℃; | 100% |
2-Aminopyrazine
2-aminopyrazine 1-oxide
Conditions | Yield |
---|---|
With hydrogen fluoride; 3-chloro-benzenecarboperoxoic acid In methanol; N,N-dimethyl-formamide at 25℃; for 1h; | 99% |
With 3-chloro-benzenecarboperoxoic acid In acetone for 24h; Ambient temperature; | 63% |
Conditions | Yield |
---|---|
With lanthanum chloride heptahydrate In neat (no solvent) at 60℃; for 0.416667h; Green chemistry; | 99% |
In neat (no solvent) at 20℃; for 2.5h; Sealed tube; Irradiation; Green chemistry; | 96% |
In neat (no solvent) at 160℃; for 1.5h; Green chemistry; | 95% |
Conditions | Yield |
---|---|
With sodium phenoxide; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; tris(dibenzylideneacetone)dipalladium (0) In 1,4-dioxane at 80℃; for 2h; | 99% |
2-Aminopyrazine
Cu2(1,1'-(1,3-phenylene)-bis(4,4-dimethylpentane-1,3-dione(2-))2
[Cu2(1,1'-(1,3-phenylene)-bis(4,4-dimethylpentane-1,3-dione(2-))2(aminopyrazine)]2
Conditions | Yield |
---|---|
In tetrahydrofuran stirred soln. of Cu-complex and ligand in THF brought to boiling, cooled; Et2O slow diffused; elem. anal.; | 99% |
Conditions | Yield |
---|---|
With pyridine at 0℃; for 2h; Inert atmosphere; | 99% |
Conditions | Yield |
---|---|
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; [(π-crotyl)Pd(BrettPhos)]OTf; potassium carbonate In tert-Amyl alcohol at 110℃; for 2h; Schlenk technique; Inert atmosphere; | 99% |
With dicyclohexyl-(2′,4′,6′-triisopropyl-3,6-dimethoxy-[1,1′-biphenyl]-2-yl)phosphine; [(π-crotyl)Pd(BrettPhos)]OTf; potassium carbonate In tert-Amyl alcohol at 110℃; for 2h; Schlenk technique; Inert atmosphere; | 99% |
2-Aminopyrazine
2-amino-3,5-dibromopyrazine
Conditions | Yield |
---|---|
With N-Bromosuccinimide In acetonitrile at 100℃; for 0.0833333h; Solvent; Microwave irradiation; | 98% |
With 2,6-dimethylpyridine; bromine In dichloromethane | 95% |
With bromine; sodium hydrogencarbonate In acetic acid 1.) 2h, 2.) 1h; | 91% |
Conditions | Yield |
---|---|
With caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene; tris(dibenzylideneacetone)dipalladium (0) In 1,4-dioxane at 100℃; for 20h; | 98% |
With copper(l) iodide; potassium carbonate; N,N`-dimethylethylenediamine In 1,4-dioxane at 100℃; for 24h; | 74% |
2-Aminopyrazine
4-methyl-benzaldehyde
β-naphthol
1-[p-methylphenyl(2-pyrazinylamino)methyl]naphthalene-2-ol
Conditions | Yield |
---|---|
In water at 20℃; for 0.666667h; | 98% |
at 125℃; for 0.0666667h; Mannich reaction; Neat (no solvent); | 89% |
2-Aminopyrazine
4-chlorobenzaldehyde
β-naphthol
1-[p-chlorophenyl(2-pyrazinylamino)methyl]naphthalene-2-ol
Conditions | Yield |
---|---|
In water at 20℃; for 0.666667h; | 98% |
at 125℃; for 0.0666667h; Mannich reaction; Neat (no solvent); | 90% |
2-Aminopyrazine
4-bromo-benzaldehyde
β-naphthol
1-[p-bromophenyl(2-pyrazinylamino)methyl]naphthalene-2-ol
Conditions | Yield |
---|---|
In water at 20℃; for 0.416667h; | 98% |
at 125℃; for 0.1h; Mannich reaction; Neat (no solvent); | 93% |
2-Aminopyrazine
N,N-dimethyl-formamide
Conditions | Yield |
---|---|
at 120℃; for 6h; Autoclave; | 98% |
2-Aminopyrazine
ethyl trifluoroacetate,
2,2,2-trifluoro-N-(pyrazin-2-yl)acetamide
Conditions | Yield |
---|---|
With dmap In tetrahydrofuran for 48h; Reflux; | 97.8% |
2-Aminopyrazine
triphenylphosphine
1,1,1-triphenyl-N-(pyrazin-2-yl)-λ5-phosphanimine
Conditions | Yield |
---|---|
With diethylazodicarboxylate In dichloromethane; toluene at 20℃; for 2.16667h; Mitsunobu type reaction; | 97% |
With hexachloroethane; triethylamine In acetonitrile 12 h, RT, then, reflux, 6 h; | 64% |
With hexachloroethane; triethylamine In benzene for 3h; Heating; | 64% |
2-Aminopyrazine
2,3-dibromopyridine
Conditions | Yield |
---|---|
With tris(dibenzylideneacetone)dipalladium (0); caesium carbonate; 4,5-bis(diphenylphos4,5-bis(diphenylphosphino)-9,9-dimethylxanthenephino)-9,9-dimethylxanthene In 1,2-dimethoxyethane at 140℃; for 24h; | A n/a B 97% |
2-Aminopyrazine
benzaldehyde
β-naphthol
1-[phenyl(2-pyrazinylamino)methyl]naphthalene-2-ol
Conditions | Yield |
---|---|
In water at 20℃; for 0.583333h; | 97% |
at 125℃; for 0.05h; Mannich reaction; Neat (no solvent); | 94% |
cis,trans-2,5-dimethoxytetrahydrofuran
2-Aminopyrazine
(pyrrolyl-1)-2 pyrazine
Conditions | Yield |
---|---|
In water at 150℃; for 0.5h; Paal-Knorr condensation; Microwave irradiation; | 97% |
5-Methylfurfural
2-Aminopyrazine
Cyclohexyl isocyanide
N-cyclohexyl-2-(5-methylfuran-2-yl)imidazo[1,2-a]pyrazin-3-amine
Conditions | Yield |
---|---|
Stage #1: 5-Methylfurfural; 2-Aminopyrazine With scandium tris(trifluoromethanesulfonate) In methanol at 20℃; for 1h; Ugi reaction; Stage #2: Cyclohexyl isocyanide In methanol Ugi reaction; | 97% |
Conditions | Yield |
---|---|
With C19H37IrN4(2+)*2I(1-); potassium carbonate at 120℃; for 24h; Inert atmosphere; Schlenk technique; Sealed tube; | 97% |
With [Cp*Ir(2-(1H-benzo[d]imidazol-2-yl)-1H-benzo[d]imidazole)Cl][Cl]; caesium carbonate at 120℃; for 12h; Schlenk technique; | 95% |
With bis[dichloro(pentamethylcyclopentadienyl)iridium(III)]; sodium hydroxide at 150℃; for 12h; Inert atmosphere; Schlenk technique; Green chemistry; | 90% |
Conditions | Yield |
---|---|
With cerium(III) chloride heptahydrate In acetonitrile at 60℃; | 97% |
2-Aminopyrazine
tert-butylisonitrile
2-ethynylbenzaldehyde
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In methanol at 20℃; for 12h; Inert atmosphere; | 96% |
2-Aminopyrazine
orthoformic acid triethyl ester
phosphonic acid diethyl ester
tetraethyl [(pyrazin-2-ylamino)methylene]bis(phosphonate)
Conditions | Yield |
---|---|
With copper(II) oxide In neat (no solvent) at 60℃; Microwave irradiation; Green chemistry; | 96% |
Conditions | Yield |
---|---|
With SingaCycle-A1; potassium hexamethylsilazane In toluene at 100℃; for 24h; Schlenk technique; Inert atmosphere; | 96% |
Conditions | Yield |
---|---|
at 25℃; for 2h; | 96% |
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