Products

Refine

Country

Business Type

Certificate

Display

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Isosorbide dimethyl ether Manufacturer/High quality/Best price/In stock

Cas:5306-85-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

1) In House standard , high quality & high purity 99% up with competitive price 2) Produce in the factory which conforms to the GMP's requirements ; 3) Quick delivery & provide free sample in 3 days after your payment Appearance:It

Dimethyl Isosorbide

Cas:5306-85-4

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Dimethyl Isosorbide supplier in China

Cas:5306-85-4

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Dimethyl Isosorbide (Novasolve DMI) is a high purity solvent and carrier which offers a safe, effective delivery enhancement mechanism for active ingredients in personal care products. Sunless tanners, facial and eye-zone treatments, skin serum

factory supply pure CAS No.:5306-85-4 Dimethylisosorbide

Cas:5306-85-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Jinan Finer Chemical Co., Ltd

Product description: Product name Isosorbide dimethyl ether CAS number 5306-85-4 Assay ≥99% Appearance Colorless transparent liquid Capacity 200mt/year Application Cosmetic r

Isosorbide dimethyl ether

Cas:5306-85-4

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Hefei TNJ chemical industry co.,ltd

TNJ Chemical Industry Co.,Ltd., is a professional manufacturers and supplier in China ,the main product include chemical pharmaceuticals and intermediates, food and feed additives, herbal extracts, agrochemicals and fine chemicals etc. It is a priv

Isosorbide Dimethyl Ether

Cas:5306-85-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Xi'an Quanao Biotech Co., Ltd.

We are: Focus on the research, production and sale of Plant and Animal extract, Medical intermediate, complete coverage six industries. Product grade: Medicine, Health care product, Cosmetics, Food,Feed, Biopesticide. Hot selling market: Europe,

Dimethyl isosorbide CAS 5306-85-4

Cas:5306-85-4

Min.Order:25 Kilogram

FOB Price: $20.0 / 24.0

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 1,4:3,6-dianhydro-2,5-di-O-methyl-D-glucitol

Cas:5306-85-4

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory price Cosmetic DIMETHYL ISOSORBIDE 5306-85-4 Manufacturer

Cas:5306-85-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Isosorbide dimethyl ether

Cas:5306-85-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Isosorbide dimethyl ether

Cas:5306-85-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

ISOSORBIDE DIMETHYL ETHER Basic information Product Name: ISOSORBIDE DIMETHYL ETHER Synonyms: ISOSORBIDE DIMETHYL ETHER;DIMETHYL ISOBORBIDE;DIMETHYL ISOSORBIDE;2,5-DI-O-METHYL-1,4:3,6-DI

TIANFU-CHEM CAS:5306-85-4 ISOSORBIDE DIMETHYL ETHER

Cas:5306-85-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Isosorbide dimethyl ether

Cas:5306-85-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 5306-85-4 with competitive price

Cas:5306-85-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Factory sells 5306-85-4 factory 5306-85-4Supply lowest price of Dimethyl isosorbide Introduction :Sartort Biopharma is a leading company engaging in the production of Intermediates, fine chemicals, Ionic liquids and 3D printing materials. It has

factory sells 5306-85-4factory 5306-85-4Supply lowest price of Dimethyl isosorbide

Cas:5306-85-4

Min.Order:25 Kilogram

FOB Price: $20.0 / 26.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

D-Glucitol,1,4:3,6-dianhydro-2,5-di-O-methyl- 5306-85-4

Cas:5306-85-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

Wuhan hanweishi Pharmchem Co., Ltd(Hanways chempharm) is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The leading products range are APIs, Hormones, Peptides

Isosorbide Dimethyl Ether CAS 5306-85-4

Cas:5306-85-4

Min.Order:100 Kilogram

FOB Price: $1.0 / 5.0

Type:Trading Company

inquiry

Leader Biochemical Group

About Our Group Since 1996 when our factory was put into production to year of 2020, our group has successively invested in more than 52 factories with shares and subordinates.We focus on manufacture Pharm & c

China Biggest Factory Manufacturer Supply ISOSORBIDE DIMETHYL ETHER CAS 5306-85-4

Cas:5306-85-4

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

ISOSORBIDE DIMETHYL ETHER

Cas:5306-85-4

Min.Order:1 Kilogram

FOB Price: $50.0 / 60.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Isosorbide dimethyl ether CAS: 5306-85-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

Isosorbide dimethyl ether CAS: 5306-85-4

Cas:5306-85-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

D-Glucitol,1,4:3,6-dianhydro-2,5-di-O-methyl-

Cas:5306-85-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 5306-85-4 Isosorbide dimethyl ether

Cas:5306-85-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

ISOSORBIDE DIMETHYL ETHER

Cas:5306-85-4

Min.Order:1 Kilogram

FOB Price: $30.0 / 50.0

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Product Detail Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,

Isosorbide Dimethyl Ether CAS NO.5306-85-4

Cas:5306-85-4

Min.Order:10 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Hangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting Isosorbide Dimethyl Ethe (DMI) CAS:5306-85-4 , Please contact us by email freely. We are leading exporter in China. If you re

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Dimethyl isosorbide

Cas:5306-85-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

D-Glucitol,1,4:3,6-dianhydro-2,5-di-O-methyl-

Cas:5306-85-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

Dimethyl isosorbide

Cas:5306-85-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Fonlynn Health Technology Co., Ltd.

Packing: According to customer requirements Delivery time: In stock or depands Port of shipment: Ningbo/Shanghai/Qingdao OEM/ODM:Welcome Sample:We can offer our existing samples at once Transportation:Express/Sea/Air Port:Ningbo/Shanghai/Qingd

Isosorbide dimethyl ether

Cas:5306-85-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

D-Glucitol,1,4:3,6-dianhydro-2,5-di-O-methyl-

Cas:5306-85-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With sodium methylate at 90℃; under 750.075 Torr; for 20h; Inert atmosphere;98%
With 1-Methylpyrrolidine at 200℃; under 15001.5 Torr; for 12h; Pressure; Reagent/catalyst; Temperature; Autoclave; chemoselective reaction;85%
CBV8014 zeolite at 200℃; for 2h;
With dmap at 20 - 150℃; for 0.283333h;
dimethyl sulfate
77-78-1

dimethyl sulfate

Isosorbide
652-67-5

Isosorbide

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Stage #1: Isosorbide With sodium hydroxide In water at 60 - 90℃;
Stage #2: dimethyl sulfate In water at 60 - 130℃;
92.4%
Stage #1: Isosorbide With sodium hydroxide In water at 60 - 90℃; for 1h; Large scale;
Stage #2: dimethyl sulfate In water at 60 - 130℃; Large scale;
59.5%
With sodium hydroxide
methylene chloride
74-87-3

methylene chloride

Isosorbide
652-67-5

Isosorbide

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Stage #1: Isosorbide With sodium hydroxide In water at 60 - 90℃;
Stage #2: methylene chloride In water at 80 - 90℃; under 3000.3 Torr;
89.5%
Stage #1: Isosorbide With sodium hydroxide In water at 60 - 90℃; Large scale;
Stage #2: methylene chloride In water at 80 - 90℃; under 3000.3 Torr; Large scale;
74%
D-sorbitol
50-70-4

D-sorbitol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

A

1,4:3,6-dianhydro-D-mannitol
641-74-7

1,4:3,6-dianhydro-D-mannitol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With triethylamine In biphenyl at 90 - 200℃; under 63756.4 Torr; for 48h; Reagent/catalyst; Autoclave; Inert atmosphere;A 14%
B 26%
C 60%
D-sorbitol
50-70-4

D-sorbitol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With 1-Methylpyrrolidine at 90 - 200℃; under 22502.3 Torr; for 72h; Pressure; Autoclave; chemoselective reaction;55%
With triethylamine In biphenyl at 200℃; under 37503.8 Torr; for 24h; Reagent/catalyst; Autoclave; Inert atmosphere;24%
trimethyl phosphite
512-56-1

trimethyl phosphite

Isosorbide
652-67-5

Isosorbide

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With iron(II) triflate In neat (no solvent) at 100℃; for 15h;54%
diethylene glycol dimethyl ether
111-96-6

diethylene glycol dimethyl ether

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With silicotungstic acid at 200℃; for 2h; Temperature; Reagent/catalyst; Overall yield = 75 %;A 14%
B 14%
C 47%
Dimethoxymethane
109-87-5

Dimethoxymethane

diethylene glycol dimethyl ether
111-96-6

diethylene glycol dimethyl ether

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Phosphotungstic acid at 100℃; for 3h; Time; Overall yield = 81 %;A 18%
B 18%
C 45%
1,2-dimethoxyethane
110-71-4

1,2-dimethoxyethane

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Silicotungstic acid at 150℃; for 5h; Reagent/catalyst; Temperature; Overall yield = 82 %;A 18%
B 21%
C 43%
With phosphotungstic acid at 150℃; for 1h; Reagent/catalyst; Autoclave;A 28%
B 18%
C 20%
Dimethoxymethane
109-87-5

Dimethoxymethane

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Amberlyst-35 at 130℃; for 15h; Overall yield = 70 %;A 20%
B 15%
C 35%
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

A

C9H14O6
1235553-26-0

C9H14O6

B

C9H14O6
1235553-25-9

C9H14O6

C

isosorbide di(methyl carbonate)
1235553-24-8

isosorbide di(methyl carbonate)

D

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With sodium methylate at 90℃; under 750.075 Torr; for 20h; Inert atmosphere;A n/a
B n/a
C n/a
D 32%
Triethylene glycol dimethyl ether
112-49-2

Triethylene glycol dimethyl ether

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Amberlyst-35 Overall yield = 52 %;A 29%
B 12%
C 11%
methoxybenzene
100-66-3

methoxybenzene

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Amberlyst-35 at 130℃; for 15h; Overall yield = 66 %;A 20%
B 18%
C 28%
1,4-dimethoxybezene
150-78-7

1,4-dimethoxybezene

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Amberlyst-35 at 130℃; for 15h; Overall yield = 63 %;A 22%
B 17%
C 24%
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

A

C9H14O6
1235553-26-0

C9H14O6

B

C9H14O6
1235553-25-9

C9H14O6

C

isosorbide di(methyl carbonate)
1235553-24-8

isosorbide di(methyl carbonate)

D

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

E

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

F

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With sodium methylate at 90℃; under 750.075 Torr; for 20h; Inert atmosphere;A n/a
B n/a
C n/a
D 8%
E n/a
F 20%
D-sorbitol
50-70-4

D-sorbitol

sodium carbonate

sodium carbonate

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HCl; water
2: aq. NaOH solution
View Scheme
3,6-anhydro-D-glucitol
53648-56-9

3,6-anhydro-D-glucitol

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: H2SO4 / 280 °C
2: aq. NaOH solution
View Scheme
3,6-anhydro-D-glucose
7625-23-2

3,6-anhydro-D-glucose

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Raney nickel; water / 110 - 120 °C / 73550.8 Torr / Hydrogenation
2: H2SO4 / 280 °C
3: aq. NaOH solution
View Scheme
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

A

C9H14O6
1235553-26-0

C9H14O6

B

C9H14O6
1235553-25-9

C9H14O6

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With potassium tert-butylate at 90℃; under 750.075 Torr; for 20h; Inert atmosphere;
With 1-Methylpyrrolidine at 200℃; under 9750.98 - 12751.3 Torr; for 6h; Time; Autoclave; chemoselective reaction;
isosorbide di(methyl carbonate)
1235553-24-8

isosorbide di(methyl carbonate)

A

(3S,3aR,6aR)hexahydro-3,6-epoxyfuro[3,2-b]furan

(3S,3aR,6aR)hexahydro-3,6-epoxyfuro[3,2-b]furan

B

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With Hydrotalcite KW200 In hexane; toluene at 240℃;A 54 %Chromat.
B 38 %Chromat.
methanol
67-56-1

methanol

Isosorbide
652-67-5

Isosorbide

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With potassium 12-tungstophosphoric acid at 225℃; for 4h; Temperature; Time; Reagent/catalyst; Inert atmosphere;
methanol
67-56-1

methanol

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With MCM-22 at 205℃; for 1h; Catalytic behavior; Reagent/catalyst; Temperature; Time; Inert atmosphere;
isosorbide di(methyl carbonate)
1235553-24-8

isosorbide di(methyl carbonate)

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With N,N-dimethyl pyrrolidinium methylcarbonate In acetonitrile at 200℃; under 11251.1 - 12751.3 Torr;
isosorbide di(methyl carbonate)
1235553-24-8

isosorbide di(methyl carbonate)

A

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With 1-Methylpyrrolidine; carbonic acid dimethyl ester at 200℃; under 11251.1 - 12751.3 Torr;
Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / 6 h / 90 °C / Dean-Stark
2: carbonic acid dimethyl ester; 1-Methylpyrrolidine / 200 °C / 11251.1 - 12751.3 Torr
View Scheme
Multi-step reaction with 2 steps
1: 200 °C / 9750.98 - 12751.3 Torr / Autoclave
2: carbonic acid dimethyl ester; 1-Methylpyrrolidine / 200 °C / 11251.1 - 12751.3 Torr
View Scheme
Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: potassium carbonate / 6 h / 90 °C / Dean-Stark
2: N,N-dimethyl pyrrolidinium methylcarbonate / acetonitrile / 200 °C / 11251.1 - 12751.3 Torr
View Scheme
Multi-step reaction with 2 steps
1: 200 °C / 9750.98 - 12751.3 Torr / Autoclave
2: N,N-dimethyl pyrrolidinium methylcarbonate / acetonitrile / 200 °C / 11251.1 - 12751.3 Torr
View Scheme
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

A

C9H14O6
1235553-26-0

C9H14O6

B

C9H14O6
1235553-25-9

C9H14O6

C

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

D

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

E

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With pyridine at 200℃; under 9750.98 - 12751.3 Torr; Autoclave; chemoselective reaction;
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

A

C9H14O6
1235553-26-0

C9H14O6

B

C9H14O6
1235553-25-9

C9H14O6

C

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

D

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With 1-Methylpyrrolidine at 200℃; under 9750.98 - 12751.3 Torr; for 12h; Reagent/catalyst; Autoclave; chemoselective reaction;
carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

Isosorbide
652-67-5

Isosorbide

A

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

B

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With dmap at 200℃; under 9750.98 - 12751.3 Torr; Reagent/catalyst; Autoclave; chemoselective reaction;
D-sorbitol
50-70-4

D-sorbitol

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

A

isosorbide di(methyl carbonate)
1235553-24-8

isosorbide di(methyl carbonate)

B

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol
162426-86-0

(1R,4S,5R,8R)-8-methoxy-2,6-dioxabicyclo[3.3.0]octanol

C

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol
6941-54-4

(1R,4S,5R,8R)-4-methoxy-2,6-dioxabicyclo[3.3.0]octanol

D

isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

Conditions
ConditionsYield
With 1-Methylpyrrolidine at 200℃; under 15001.5 Torr; for 20h; Autoclave; chemoselective reaction;
isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

A

di-O-methyl-1,4:3,6-dianhydro-D-mannitol
121693-37-6

di-O-methyl-1,4:3,6-dianhydro-D-mannitol

B

di-O-methyl-1,4:3,6-dianhydro-L-iditol

di-O-methyl-1,4:3,6-dianhydro-L-iditol

Conditions
ConditionsYield
With 2,3,5-trimethyl-pyridine; 2,2-bis(tert-butylperoxy)butane; tri-tert-butoxysilanethiol In octane at 125℃; for 5h;
With 1-(2,4,6-triisopropylphenylsulfonyl)-1H-1,2,4-triazole In octane at 125℃; for 4h; Product distribution; Further Variations:; Reagents;
isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

A

C6H10O4

C6H10O4

B

C7H12O4

C7H12O4

C

C8H14O4

C8H14O4

Conditions
ConditionsYield
With 5 wt% ruthenium/carbon; hydrogen In water at 160℃; under 18751.9 Torr; for 3h; Autoclave;
isosorbide dimethyl ether
5306-85-4

isosorbide dimethyl ether

A

C6(2)H10O4

C6(2)H10O4

B

C7(2)H12O4

C7(2)H12O4

C

C8(2)H14O4

C8(2)H14O4

Conditions
ConditionsYield
With 5 wt% ruthenium/carbon; hydrogen; water-d2 at 160℃; under 18751.9 Torr; for 3h; Autoclave;
Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View