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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Equol Manufacturer/High quality/Best price/In stock

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) W

98% up by HPLC Equol 94105-90-5 531-95-3

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $825.0 / 1100.0

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

Equol manufacturer/supplier

Cas:531-95-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

shanghai Tauto Biotech Co., Ltd

18-year experience in Phytochemicals Each product has passed very strict tests (NMR\MS\HPLC) Agents in 13 countries Certified by ISO 9001:2008 quality management system Leader Supplier of Botanical Reference Materials in China

Equol

Cas:531-95-3

Min.Order:10 Milligram

Negotiable

Type:Manufacturers

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Off white solid Off white solid Identity[IR] Authentic

High purity Equol CAS:531-95-3

Cas:531-95-3

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Equol

Cas:531-95-3

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Equol 531-95-3 GMP Manufacturer

Cas:531-95-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

equol CAS: 531-95-3 Molecular Formula: C15H14O3 Home Product Category Organic raw materials Phenolic compounds 531-95-3 531-95-3 - Names and Identifiers Name equol Synonyms Equol equol S-Equol S,R-equol

Factory high quality Equol CAS 531-95-3

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $159.0 / 170.0

Type:Trading Company

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

(S)-(-)-Equol

Cas:531-95-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

531-95-3 Equol

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM- Equol

Cas:531-95-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Wholesale price CAS 531-95-3 with best price

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

Equol

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $50.0 / 100.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2H-1-Benzopyran-7-ol,3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)- 531-95-3

Cas:531-95-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Hangzhou Ocean Chemical Co., Ltd.

★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support ★.Shortest delivery time . Appearance:Refer to COA Storage:Store in dry, cool and ventilated place Package:Acc

Equol

Cas:531-95-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Equol CAS:531-95-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroi

Equol CAS:531-95-3

Cas:531-95-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2H-1-Benzopyran-7-ol,3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-

Cas:531-95-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competitive price in

CAS 531-95-3 Equol

Cas:531-95-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Leader Biochemical Group

Overview of Our Factories Our Factories production lines Our Factories R&D ability Our Factories warehouse Our Factorie

China Biggest Factory & Manufacturer supply Equol

Cas:531-95-3

Min.Order:1 Gram

FOB Price: $5.0 / 10.0

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2H-1-Benzopyran-7-ol,3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-

Cas:531-95-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Miheng Trading Co., Ltd.

Equol CAS 531-95-3 Our advantage 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professio

Equol CAS 531-95-3

Cas:531-95-3

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Equol cas 531-95-3

Cas:531-95-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Equol

Cas:531-95-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Spring & Autumn Biological Engineering Co., Ltd.

Nanjing Spring & Autumn Biological Engineering Co., Ltd. Which was founded at 2008, has an R & D team composed very experienced natural products chemists. The company is a high-tech enterprise engaged in functional health care products raw ma

Professional Supply Bulk Powser Anti-Hairloss CAS 531-95-3 S-Equol / S Equol

Cas:531-95-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2H-1-Benzopyran-7-ol,3,4-dihydro-3-(4-hydroxyphenyl)-, (3S)-

Cas:531-95-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High purity Equol

Cas:531-95-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Equol cas 531-95-3

Cas:531-95-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Equol

Cas:531-95-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Equol

Cas:531-95-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Synthetic route

Conditions
ConditionsYield
With Eggerthella sp. YY7918 at 37℃; for 72h;100%
daidzein
486-66-8

daidzein

equol
531-95-3

equol

Conditions
ConditionsYield
With Eggerthella sp. YY7918 at 37℃; for 72h;100%
With 5%-palladium/activated carbon; hydrogen; acetic acid In ethanol; water at 20℃; under 760.051 Torr; for 10h;95%
C29H26O3

C29H26O3

equol
531-95-3

equol

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen In tetrahydrofuran; methanol; water at 20℃; for 0.75h;100%
C36H29Br3O4
1208255-82-6

C36H29Br3O4

equol
531-95-3

equol

Conditions
ConditionsYield
Stage #1: C36H29Br3O4 With lithium aluminium tetrahydride In diethyl ether for 3h;
Stage #2: With water In diethyl ether Cooling with ice;
95%
(S)-7-(methoxymethoxy)-3-(4'-methoxymethoxy)-phenylchroman
922179-56-4

(S)-7-(methoxymethoxy)-3-(4'-methoxymethoxy)-phenylchroman

equol
531-95-3

equol

Conditions
ConditionsYield
With hydrogenchloride; methanol In dichloromethane at 4.8 - 20℃; for 6h;93%
With hydrogenchloride In tetrahydrofuran; methanol; water at 60℃; for 0.333333h; Inert atmosphere;92%
(S)-4-(3-bromo-2-(4-hydroxyphenyl)propyl)benzene-1,3-diol
1383121-33-2

(S)-4-(3-bromo-2-(4-hydroxyphenyl)propyl)benzene-1,3-diol

equol
531-95-3

equol

Conditions
ConditionsYield
With potassium carbonate In acetone at 50℃; for 8h;91%
With potassium carbonate In acetone at 50℃; for 8h;110 mg
(S)-7-methoxy-3-(4-methoxyphenyl)chromane
3722-56-3

(S)-7-methoxy-3-(4-methoxyphenyl)chromane

equol
531-95-3

equol

Conditions
ConditionsYield
With pyridine at 150℃; Inert atmosphere;88%
With pyridine hydrogenfluoride In neat (no solvent) at 150℃; for 48h; Inert atmosphere;82%
With pyridine hydrochloride at 160℃; for 48h; Inert atmosphere; Schlenk technique;72%
With pyridine hydrochloride at 150℃; for 28h;66%
(S)-7-methoxy-3-(4-methoxyphenyl)spiro[chroman-2,2'-[1,3]dithiane]
1404301-87-6

(S)-7-methoxy-3-(4-methoxyphenyl)spiro[chroman-2,2'-[1,3]dithiane]

equol
531-95-3

equol

Conditions
ConditionsYield
Stage #1: (S)-7-methoxy-3-(4-methoxyphenyl)spiro[chroman-2,2'-[1,3]dithiane] With hydrogen
Stage #2: With pyridine; hydrogenchloride at 150℃;
63%
ethylmagnesium iodide
10467-10-4

ethylmagnesium iodide

(S)-7-methoxy-3-(4-methoxyphenyl)chromane
3722-56-3

(S)-7-methoxy-3-(4-methoxyphenyl)chromane

equol
531-95-3

equol

Conditions
ConditionsYield
at 180℃;
daidzein
486-66-8

daidzein

A

(+)-Equol

(+)-Equol

B

equol
531-95-3

equol

Conditions
ConditionsYield
With ammonium formate; acetic acid; palladium dihydroxide for 1h; Heating;
Multi-step reaction with 3 steps
1: palladium 10% on activated carbon; ammonium formate / methanol / 4 h / 50 °C / Inert atmosphere
2: [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); triethylamine; hydrogen / methanol / 19 h / 60 °C / 7500.75 Torr / Inert atmosphere; Autoclave
3: palladium 10% on activated carbon; acetic acid; hydrogen / methanol / 4 h / 60 °C / 5250.53 Torr / Autoclave
View Scheme
3,4-dihydro-7-hydroxy-3-(4-methoxyphenyl)-2H-1-benzopyran
10499-17-9

3,4-dihydro-7-hydroxy-3-(4-methoxyphenyl)-2H-1-benzopyran

A

(+)-Equol

(+)-Equol

B

equol
531-95-3

equol

Conditions
ConditionsYield
With aluminium trichloride; ethanethiol In dichloromethane at 0℃; for 1h;
Conditions
ConditionsYield
In ethanol; hexane for 0 - 0.283333h; Resolution of racemate;
With CYCLOBOND I 2000 RSP In formic acid; water; acetonitrile Resolution of racemate;
With cellulose (3,5-dimethylphenylcarbamate) coated reduced graphene oxide(at)silica gel In hexane; isopropyl alcohol at 25℃; Resolution of racemate; enantioselective reaction;
(S)-3-(2-bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propan-1-ol
917379-11-4

(S)-3-(2-bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propan-1-ol

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 46 percent / 2-(di-tert-butylphosphino)-1,1'-binaphthyl; Cs2CO3; Pd(OAc)2 / toluene / 22 h / 50 °C
2: 66 percent / pyridine hydrochloride / 28 h / 150 °C
View Scheme
(S)-4-benzyl-3-((S)-3-(2-bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propanoyl)-2-oxazolidinone
917379-10-3

(S)-4-benzyl-3-((S)-3-(2-bromo-4-methoxyphenyl)-2-(4-methoxyphenyl)propanoyl)-2-oxazolidinone

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 96 percent / LiAlH4 / tetrahydrofuran / 0.25 h / cooling
2: 46 percent / 2-(di-tert-butylphosphino)-1,1'-binaphthyl; Cs2CO3; Pd(OAc)2 / toluene / 22 h / 50 °C
3: 66 percent / pyridine hydrochloride / 28 h / 150 °C
View Scheme
4-Methoxyphenylacetic acid
104-01-8

4-Methoxyphenylacetic acid

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: SOCl2 / 2 h / Heating
2: 237 g / n-BuLi / tetrahydrofuran; hexane / -65 - 20 °C
3: 167.4 g / NaHMDS / tetrahydrofuran / 0.17 h / cooling
4: 96 percent / LiAlH4 / tetrahydrofuran / 0.25 h / cooling
5: 46 percent / 2-(di-tert-butylphosphino)-1,1'-binaphthyl; Cs2CO3; Pd(OAc)2 / toluene / 22 h / 50 °C
6: 66 percent / pyridine hydrochloride / 28 h / 150 °C
View Scheme
Multi-step reaction with 6 steps
1.1: acetic anhydride; triethylamine / 2 h / Reflux
2.1: C56H72IrNOP; hydrogen; triethylamine / methanol / 72 h / 70 °C / 9120.61 Torr
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.25 h / 0 - 20 °C
3.2: 0 °C
4.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 20 °C / Cooling with ice
5.1: boron tribromide / dichloromethane / 19 h / -78 - 20 °C
6.1: potassium carbonate / acetone / 8 h / 50 °C
View Scheme
Multi-step reaction with 6 steps
1.1: oxalyl dichloride / benzene / 24 h / 20 °C
2.1: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C
3.1: hydrogen; 10% Pd/C / ethyl acetate / 20 °C / 750.08 Torr
4.1: trimethylaluminum / dichloromethane; hexane / 0 - 20 °C / Inert atmosphere
4.2: Inert atmosphere
5.1: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate / cyclohexane / 60 h / 20 °C / Molecular sieve
6.1: hydrogen
6.2: 150 °C
View Scheme
Multi-step reaction with 8 steps
1.1: thionyl chloride / 2 h / Inert atmosphere
2.1: n-butyllithium / tetrahydrofuran / 2 h / -65 - -45 °C / Inert atmosphere
3.1: N-ethyl-N,N-diisopropylamine; di-n-butylboryl trifluoromethanesulfonate / dichloromethane / 3.5 h / -25 - -15 °C / Inert atmosphere
3.2: 1.83 h / -25 - 15 °C / Inert atmosphere
4.1: triethylsilane; trifluoroacetic acid / dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere
5.1: hydrogenchloride / methanol / 0.5 h / Reflux; Inert atmosphere
6.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
7.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere
8.1: pyridine / 150 °C / Inert atmosphere
View Scheme
(4S)-3-<2-(4-Methoxyphenyl)-1-oxoethyl>-4-(phenylmethyl)-2-oxazolidinone
143589-97-3

(4S)-3-<2-(4-Methoxyphenyl)-1-oxoethyl>-4-(phenylmethyl)-2-oxazolidinone

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 167.4 g / NaHMDS / tetrahydrofuran / 0.17 h / cooling
2: 96 percent / LiAlH4 / tetrahydrofuran / 0.25 h / cooling
3: 46 percent / 2-(di-tert-butylphosphino)-1,1'-binaphthyl; Cs2CO3; Pd(OAc)2 / toluene / 22 h / 50 °C
4: 66 percent / pyridine hydrochloride / 28 h / 150 °C
View Scheme
4-methoxyphenyl-acetic chloride
4693-91-8

4-methoxyphenyl-acetic chloride

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 237 g / n-BuLi / tetrahydrofuran; hexane / -65 - 20 °C
2: 167.4 g / NaHMDS / tetrahydrofuran / 0.17 h / cooling
3: 96 percent / LiAlH4 / tetrahydrofuran / 0.25 h / cooling
4: 46 percent / 2-(di-tert-butylphosphino)-1,1'-binaphthyl; Cs2CO3; Pd(OAc)2 / toluene / 22 h / 50 °C
5: 66 percent / pyridine hydrochloride / 28 h / 150 °C
View Scheme
Multi-step reaction with 5 steps
1.1: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C
2.1: hydrogen; 10% Pd/C / ethyl acetate / 20 °C / 750.08 Torr
3.1: trimethylaluminum / dichloromethane; hexane / 0 - 20 °C / Inert atmosphere
3.2: Inert atmosphere
4.1: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate / cyclohexane / 60 h / 20 °C / Molecular sieve
5.1: hydrogen
5.2: 150 °C
View Scheme
Multi-step reaction with 7 steps
1.1: n-butyllithium / tetrahydrofuran / 2 h / -65 - -45 °C / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine; di-n-butylboryl trifluoromethanesulfonate / dichloromethane / 3.5 h / -25 - -15 °C / Inert atmosphere
2.2: 1.83 h / -25 - 15 °C / Inert atmosphere
3.1: triethylsilane; trifluoroacetic acid / dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere
4.1: hydrogenchloride / methanol / 0.5 h / Reflux; Inert atmosphere
5.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
6.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere
7.1: pyridine / 150 °C / Inert atmosphere
View Scheme
7-Hydroxy-3-(4-methoxy-phenyl)-chromen-4-on
485-72-3

7-Hydroxy-3-(4-methoxy-phenyl)-chromen-4-on

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 68 percent / acetic acid; ammonium formate / Pd(OH)2 / 1 h / Heating
2: aluminum trichloride; ethane thiol / CH2Cl2 / 1 h / 0 °C
View Scheme
C16H17BrO3

C16H17BrO3

equol
531-95-3

equol

Conditions
ConditionsYield
With potassium carbonate In acetone
daidzein
486-66-8

daidzein

B

C15H12O3

C15H12O3

C

idronoxil
81267-65-4

idronoxil

D

equol
531-95-3

equol

Conditions
ConditionsYield
With 5%-palladium/activated carbon; hydrogen; acetic acid In ethanol at 20℃; for 10h;
(S)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)propan-1-ol
1057663-19-0

(S)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)propan-1-ol

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 20 °C / Cooling with ice
2: boron tribromide / dichloromethane / 19 h / -78 - 20 °C
3: potassium carbonate / acetone / 8 h / 50 °C
View Scheme
(S)-1-(3-bromo-2-(4-methoxyphenyl)propyl)-2,4-dimethoxy-benzene
1057663-20-3

(S)-1-(3-bromo-2-(4-methoxyphenyl)propyl)-2,4-dimethoxy-benzene

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: boron tribromide / dichloromethane / 19 h / -78 - 20 °C
2: potassium carbonate / acetone / 8 h / 50 °C
View Scheme
Stage #1: (S)-1-(3-bromo-2-(4-methoxyphenyl)propyl)-2,4-dimethoxy-benzene With boron tribromide In dichloromethane at -78 - 20℃; for 19h; Inert atmosphere;
Stage #2: With potassium carbonate In acetone at 50℃; for 8h;
63.1 mg
(S)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)propionic acid
1383121-29-6

(S)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)propionic acid

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.25 h / 0 - 20 °C
1.2: 0 °C
2.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 20 °C / Cooling with ice
3.1: boron tribromide / dichloromethane / 19 h / -78 - 20 °C
4.1: potassium carbonate / acetone / 8 h / 50 °C
View Scheme
(E)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylic acid
73867-36-4

(E)-3-(2,4-dimethoxyphenyl)-2-(4-methoxyphenyl)acrylic acid

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: C56H72IrNOP; hydrogen; triethylamine / methanol / 72 h / 70 °C / 9120.61 Torr
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.25 h / 0 - 20 °C
2.2: 0 °C
3.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 20 °C / Cooling with ice
4.1: boron tribromide / dichloromethane / 19 h / -78 - 20 °C
5.1: potassium carbonate / acetone / 8 h / 50 °C
View Scheme
2,4-Dimethoxybenzaldehyde
613-45-6

2,4-Dimethoxybenzaldehyde

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: acetic anhydride; triethylamine / 2 h / Reflux
2.1: C56H72IrNOP; hydrogen; triethylamine / methanol / 72 h / 70 °C / 9120.61 Torr
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2.25 h / 0 - 20 °C
3.2: 0 °C
4.1: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 20 °C / Cooling with ice
5.1: boron tribromide / dichloromethane / 19 h / -78 - 20 °C
6.1: potassium carbonate / acetone / 8 h / 50 °C
View Scheme
Multi-step reaction with 6 steps
1.1: pyridine; piperidine / 3.5 h / 125 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / Reflux; Inert atmosphere
3.1: pyridinium chlorochromate / dichloromethane / 1 h / 20 °C / Molecular sieve
4.1: copper(I) bromide; sodium hydrogencarbonate; (2R,5R)-2-tert-butyl-3-methyl-5-phenyl-4-imidazolidinone trichloroacetic acid salt / toluene; diethyl ether / 44 h / 20 °C
5.1: sodium tetrahydroborate / methanol; dichloromethane; toluene; diethyl ether / 1 h / 23 °C
5.2: 3 h / 0 - 20 °C
6.1: boron tribromide / dichloromethane / 19 h / -78 - 20 °C / Inert atmosphere
6.2: 8 h / 50 °C
View Scheme
7-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one
3173-00-0

7-methoxy-3-(4-methoxyphenyl)-2H-chromen-2-one

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: hydrogen; 10% Pd/C / ethyl acetate / 20 °C / 750.08 Torr
2.1: trimethylaluminum / dichloromethane; hexane / 0 - 20 °C / Inert atmosphere
2.2: Inert atmosphere
3.1: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate / cyclohexane / 60 h / 20 °C / Molecular sieve
4.1: hydrogen
4.2: 150 °C
View Scheme
7-methoxy-3-(4-methoxyphenyl)hydrocoumarin
1404301-54-7

7-methoxy-3-(4-methoxyphenyl)hydrocoumarin

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: trimethylaluminum / dichloromethane; hexane / 0 - 20 °C / Inert atmosphere
1.2: Inert atmosphere
2.1: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate / cyclohexane / 60 h / 20 °C / Molecular sieve
3.1: hydrogen
3.2: 150 °C
View Scheme
2-(2-(1,3-dithian-2-ylidene)-2-(4-methoxyphenyl)ethyl)-5-methoxyphenol
1404301-69-4

2-(2-(1,3-dithian-2-ylidene)-2-(4-methoxyphenyl)ethyl)-5-methoxyphenol

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate / cyclohexane / 60 h / 20 °C / Molecular sieve
2.1: hydrogen
2.2: 150 °C
View Scheme
2-Hydroxy-4-methoxybenzaldehyde
673-22-3

2-Hydroxy-4-methoxybenzaldehyde

equol
531-95-3

equol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium carbonate; tetra(n-butyl)ammonium hydrogensulfate / dichloromethane; water / 20 °C
2.1: hydrogen; 10% Pd/C / ethyl acetate / 20 °C / 750.08 Torr
3.1: trimethylaluminum / dichloromethane; hexane / 0 - 20 °C / Inert atmosphere
3.2: Inert atmosphere
4.1: (R)-3,3'-bis[3,5-di(trifluoromethyl)phenyl]-1,1'-binaphthyl phosphate / cyclohexane / 60 h / 20 °C / Molecular sieve
5.1: hydrogen
5.2: 150 °C
View Scheme
Multi-step reaction with 7 steps
1.1: N-ethyl-N,N-diisopropylamine / dichloromethane / 0.5 h / Cooling with ice; Inert atmosphere
1.2: 20 h / Inert atmosphere
2.1: N-ethyl-N,N-diisopropylamine; di-n-butylboryl trifluoromethanesulfonate / dichloromethane / 3.5 h / -25 - -15 °C / Inert atmosphere
2.2: 1.83 h / -25 - 15 °C / Inert atmosphere
3.1: triethylsilane; trifluoroacetic acid / dichloromethane / 0.67 h / 0 - 20 °C / Inert atmosphere
4.1: hydrogenchloride / methanol / 0.5 h / Reflux; Inert atmosphere
5.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere
6.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 6 h / 20 °C / Inert atmosphere
7.1: pyridine / 150 °C / Inert atmosphere
View Scheme
equol
531-95-3

equol

methyl iodide
74-88-4

methyl iodide

(S)-7-methoxy-3-(4-methoxyphenyl)chromane
3722-56-3

(S)-7-methoxy-3-(4-methoxyphenyl)chromane

Conditions
ConditionsYield
With potassium carbonate In acetone at 60℃; Schlenk technique; Inert atmosphere;97%
dimethylallyl diphosphate
358-72-5

dimethylallyl diphosphate

equol
531-95-3

equol

A

4'-(dimethylallyl)equol

4'-(dimethylallyl)equol

B

7-(dimethylallyl)equol

7-(dimethylallyl)equol

Conditions
ConditionsYield
With recombinant O-prenyltransferase from Antrodia camphorata In aq. buffer at 37℃; for 12h; pH=7; Enzymatic reaction;A 27.3%
B 15.6%
dimethyl sulfate
77-78-1

dimethyl sulfate

equol
531-95-3

equol

(S)-7-methoxy-3-(4-methoxyphenyl)chromane
3722-56-3

(S)-7-methoxy-3-(4-methoxyphenyl)chromane

Conditions
ConditionsYield
With sodium hydroxide
equol
531-95-3

equol

(S)-7-Benzoyloxy-3-(4-benzoyloxy-phenyl)-chroman

(S)-7-Benzoyloxy-3-(4-benzoyloxy-phenyl)-chroman

equol
531-95-3

equol

(-)-Di-O-acetyl-equol
21140-91-0

(-)-Di-O-acetyl-equol

equol
531-95-3

equol

potassium hydroxide

potassium hydroxide

A

4-hydroxysalicylic acid
89-86-1

4-hydroxysalicylic acid

B

4-[2-(4-hydroxy-phenyl)-propenyl]-resorcinol

4-[2-(4-hydroxy-phenyl)-propenyl]-resorcinol

C

4-hydroxy-benzoic acid
99-96-7

4-hydroxy-benzoic acid

Conditions
ConditionsYield
at 240℃;
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

equol
531-95-3

equol

C21H30O3Si2
81910-32-9

C21H30O3Si2

Conditions
ConditionsYield
With pyridine at 65℃; for 0.5h;
N-methyl-N-tert-butyldimethylsilyl-1,1,1-trifluoroacetamide
77377-52-7

N-methyl-N-tert-butyldimethylsilyl-1,1,1-trifluoroacetamide

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

equol
531-95-3

equol

C27H42O3Si2

C27H42O3Si2

Conditions
ConditionsYield
at 100℃; for 1h;
bromobutyric acid
2623-87-2

bromobutyric acid

equol
531-95-3

equol

C23H26O7

C23H26O7

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 25℃; for 4h;

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