As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:538-09-0
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
Cas:538-09-0
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryService we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to your requirem
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:538-09-0
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:538-09-0
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:538-09-0
Min.Order:1 Kilogram
FOB Price: $7.0 / 9.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:538-09-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryNortropine CAS:538-09-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s
Cas:538-09-0
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:538-09-0
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:538-09-0
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:538-09-0
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquiryGMP factoryFull experience of large numbers containers loading in main Chinese seaports Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Rich experience for
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Product name: Nortropine CAS No.:538-09-0 Molecule Formula:C7H13NO Molecule Weight:122.16 Purity: 99% Package: 25kg/drum Description:Light yellow powder Manufacture Standards:Enterprise Standard TESTING ITEMS SPEC
Cas:538-09-0
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryGMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Nortropine Chemical Properties Melting point 108-110°C Boiling point 229.6 °C density 1.096 refractive index 1.52 Fp 116.8 °C storage temp. Refrigerator pka 14.89±0.20(Predicted)
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
Cas:538-09-0
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Conditions | Yield |
---|---|
With DAP(2+)*2BF4(1-); oxygen In acetonitrile at 20℃; Irradiation; | 87% |
With DAP(2+)*2BF4(1-); oxygen In acetonitrile at 20℃; Product distribution; Irradiation; photochemical N-demethylation of var. tert. amines; | 87% |
With sodium hydroxide; water; potassium hexacyanoferrate(III) |
Conditions | Yield |
---|---|
iron In isopropyl alcohol at 60℃; for 2h; Product distribution / selectivity; | A 84% B 5% |
Stage #1: tropine-N-oxide hydrochloride With ferrocene In chloroform for 24h; Reflux; Stage #2: With sodium hydroxide In chloroform; water | A 74% B 8% |
Conditions | Yield |
---|---|
With hydrogen In methanol at 25 - 30℃; under 7500.75 Torr; for 24h; | 83% |
(1R,3R,5S)-3-Benzyloxy-8-(toluene-4-sulfonyl)-8-aza-bicyclo[3.2.1]octane
nortropine
Conditions | Yield |
---|---|
With sodium In ammonia | 81% |
3-tropanol
A
(1R,3R,5S)-3-Hydroxy-8-aza-bicyclo[3.2.1]octane-8-carbaldehyde
B
nortropine
Conditions | Yield |
---|---|
With oxygen; lithium perchlorate; 9,10-Dicyanoanthracene In acetonitrile at 20℃; Irradiation; | A 15% B 85 % Spectr. |
With oxygen; 9,10-Dicyanoanthracene In acetonitrile at 20℃; Irradiation; | A 27 % Spectr. B 73 % Spectr. |
(1R,3r,5S)-8-acetyl-8-azabicyclo[3.2.1]octan-3-yl acetate
sulfuric acid
nortropine
nortropine
Conditions | Yield |
---|---|
With potassium hydroxide |
nortropine
nortropine
Conditions | Yield |
---|---|
With barium dihydroxide |
nortropine
Conditions | Yield |
---|---|
With potassium hydroxide |
nortropine
Conditions | Yield |
---|---|
With barium dihydroxide Hydrolysis; |
nortropine
Conditions | Yield |
---|---|
With hydrogenchloride |
Conditions | Yield |
---|---|
in alkal.Loesung; |
nortropine
Conditions | Yield |
---|---|
With acetic anhydride Erwaermen einer Loesung des Reaktionsprodukts in wss. Natronlauge; |
2-phenyl-propionic acid nortropan-3-yl ester
A
hydratropic acid
B
nortropine
Conditions | Yield |
---|---|
Hydrolysis; |
Conditions | Yield |
---|---|
With methanol; potassium hydroxide for 3h; Heating; |
6-(benzyloxy)-1,3-cycloheptadiene
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1: 77 percent / LiCl, p-benzoquinone / Pd(OAc)2 (7percent) / acetic acid 2: 64 percent / Pd(PPh3)4 (3percent) / acetonitrile; dimethylsulfoxide / 12 h / 20 °C 3: 95 percent / H2 / RhCl(PPh3)3 / ethanol / 15 h / 20 °C / 4560 Torr 4: 95 percent / NaOH / methanol; H2O 5: 95 percent / EtO2C-N=N-CO2Et, ZnCl2, PBu3 / 3 h / 20 °C 6: 90 percent / K2CO3 / methanol / 1 h / 20 °C 7: 81 percent / Na / NH3 View Scheme |
1β-acetoxy-4β-chloro-6α-(benzyloxy)-2-cycloheptene
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: 64 percent / Pd(PPh3)4 (3percent) / acetonitrile; dimethylsulfoxide / 12 h / 20 °C 2: 95 percent / H2 / RhCl(PPh3)3 / ethanol / 15 h / 20 °C / 4560 Torr 3: 95 percent / NaOH / methanol; H2O 4: 95 percent / EtO2C-N=N-CO2Et, ZnCl2, PBu3 / 3 h / 20 °C 5: 90 percent / K2CO3 / methanol / 1 h / 20 °C 6: 81 percent / Na / NH3 View Scheme |
N-((1R,3S,5R)-3-Benzyloxy-5-chloro-cycloheptyl)-4-methyl-benzenesulfonamide
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90 percent / K2CO3 / methanol / 1 h / 20 °C 2: 81 percent / Na / NH3 View Scheme |
N-((1R,3S,5S)-3-Benzyloxy-5-hydroxy-cycloheptyl)-4-methyl-benzenesulfonamide
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 95 percent / EtO2C-N=N-CO2Et, ZnCl2, PBu3 / 3 h / 20 °C 2: 90 percent / K2CO3 / methanol / 1 h / 20 °C 3: 81 percent / Na / NH3 View Scheme |
Acetic acid (1S,3S,5R)-3-benzyloxy-5-(toluene-4-sulfonylamino)-cycloheptyl ester
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 95 percent / NaOH / methanol; H2O 2: 95 percent / EtO2C-N=N-CO2Et, ZnCl2, PBu3 / 3 h / 20 °C 3: 90 percent / K2CO3 / methanol / 1 h / 20 °C 4: 81 percent / Na / NH3 View Scheme |
Acetic acid (1R,4S,6S)-6-benzyloxy-4-(toluene-4-sulfonylamino)-cyclohept-2-enyl ester
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 95 percent / H2 / RhCl(PPh3)3 / ethanol / 15 h / 20 °C / 4560 Torr 2: 95 percent / NaOH / methanol; H2O 3: 95 percent / EtO2C-N=N-CO2Et, ZnCl2, PBu3 / 3 h / 20 °C 4: 90 percent / K2CO3 / methanol / 1 h / 20 °C 5: 81 percent / Na / NH3 View Scheme |
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: aqueous KOH-solution 2: water; potassium hexacyanoferrate(III); NaOH-solution View Scheme |
(1R,3S,5S)-tert-butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
nortropine
Conditions | Yield |
---|---|
With hydrogenchloride In 1,4-dioxane for 1h; |
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: hydrogenchloride; disodium hydrogenphosphate / 25 - 30 °C 2: hydrogen; 5%-palladium/activated carbon / water; methanol / 16 h 3: hydrogen / methanol / 24 h / 25 - 30 °C / 7500.75 Torr View Scheme |
8-benzyl-3-oxo-8-azabicyclo[3.2.1]octane hydrochloride
nortropine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogen; 5%-palladium/activated carbon / water; methanol / 16 h 2: hydrogen / methanol / 24 h / 25 - 30 °C / 7500.75 Torr View Scheme |
di-tert-butyl dicarbonate
nortropine
(1R,3S,5S)-tert-butyl 3-hydroxy-8-azabicyclo[3.2.1]octane-8-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; for 12h; | 100% |
In tetrahydrofuran at 20℃; | 97% |
With triethylamine In dichloromethane at 20℃; for 16h; | 97% |
nortropine
Conditions | Yield |
---|---|
With nitrogen(II) oxide; calcium hydroxide In water at 20℃; under 12929 Torr; for 160h; Green chemistry; | 96% |
Conditions | Yield |
---|---|
With sodium tetrahydroborate | 95% |
With methanol; nickel Hydrogenation; |
acetic anhydride
nortropine
(1R,3r,5S)-8-acetyl-8-azabicyclo[3.2.1]octan-3-yl acetate
Conditions | Yield |
---|---|
With pyridine; dmap at 20℃; for 21h; Inert atmosphere; | 94.4% |
nortropine
Conditions | Yield |
---|---|
Stage #1: 3-[4-(3,3-diethyltriaz-1-enyl)phenoxy]propyloxymethylpolystyrene With trifluoroacetic acid In dichloromethane at -10℃; for 0.166667h; Stage #2: nortropine In methanol; dichloromethane at -10 - 20℃; Further stages.; | 94% |
4-fluoronaphthalene-1-carbonitrile
nortropine
4-(3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl)naphthalene-1-carbonitrile
Conditions | Yield |
---|---|
With pyridine at 220℃; for 0.0833333h; Microwave irradiation; | 92% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50 - 70℃; under 750.075 Torr; for 6h; Inert atmosphere; | 92% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50℃; under 750.075 Torr; for 1h; Inert atmosphere; | 89% |
Conditions | Yield |
---|---|
With hydrogenchloride; dichloromethane; sodium carbonate In acetonitrile for 7.5h; Heating; | 87.2% |
nortropine
4-fluoro-2-(trifluoromethyl)benzonitrile
Conditions | Yield |
---|---|
With pyridine at 100℃; for 6h; | 85% |
Conditions | Yield |
---|---|
With thionyl chloride solid phase reaction; | 85% |
levofloxacin Q-acid
nortropine
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 160℃; for 5h; | 82.4% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50℃; under 750.075 Torr; for 1h; Inert atmosphere; | 79% |
9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]-benzoxazine-6-carboxylic acid
nortropine
Conditions | Yield |
---|---|
In dimethyl sulfoxide at 160℃; for 5h; | 76% |
nortropine
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃; | 73.8% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50 - 70℃; under 750.075 Torr; for 2h; Inert atmosphere; | 73% |
iodobenzene
carbon monoxide
nortropine
B
((1R,3R,5S)-3-hydroxy-8-azabicyclo[3.2.1]octan-8-yl)(phenyl)methanone
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50℃; under 750.075 Torr; Inert atmosphere; | A 30% B 68% |
Conditions | Yield |
---|---|
With potassium carbonate In benzene for 3h; Heating; | 65% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50℃; under 750.075 Torr; for 1h; Inert atmosphere; | 65% |
2-chloro-4-fluorobenzonitrile
nortropine
Conditions | Yield |
---|---|
With pyridine at 110℃; for 20h; | 63% |
2-chloro-4-fluorobenzonitrile
nortropine
2-chloro-4-(3-endo-hydroxy-8-azabicyclo[3.2.1]oct-8-yl)benzonitrile
Conditions | Yield |
---|---|
With pyridine at 110℃; for 20h; | 63% |
carbon monoxide
(1S,4R)-2-iodo-1,7,7-trimethylbicyclo[2.2.1]hept-2-ene
nortropine
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50℃; under 750.075 Torr; for 1h; Inert atmosphere; | 63% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50 - 70℃; under 750.075 Torr; for 2h; Inert atmosphere; | 62% |
Conditions | Yield |
---|---|
In benzene for 5h; Heating; | 61% |
nortropine
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine In N,N-dimethyl-formamide at 20℃; | 55.6% |
Conditions | Yield |
---|---|
With palladium diacetate; triethylamine; triphenylphosphine In N,N-dimethyl-formamide at 50℃; under 750.075 Torr; for 6h; Inert atmosphere; | 55% |
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