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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Cyanophenylacetic acid Manufacturer/High quality/Best price/In stock

Cas:5462-71-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

4-Cyanophenylacetic acid

Cas:5462-71-5

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Cyanophenylacetic acid

Cas:5462-71-5

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Discount price CAS 5462-71-5 with best quality

Cas:5462-71-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W

4-CYANOPHENYLACETIC ACID CAS5462-71-5

Cas:5462-71-5

Min.Order:1 Kilogram

FOB Price: $6.0 / 8.0

Type:Trading Company

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzeneacetic acid,4-cyano- 5462-71-5

Cas:5462-71-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

4-CYANOPHENYLACETIC ACID CAS:5462-71-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic i

4-CYANOPHENYLACETIC ACID CAS:5462-71-5

Cas:5462-71-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzeneacetic acid,4-cyano-

Cas:5462-71-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzeneacetic acid,4-cyano-

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-cyanophenylacetic acid

Cas:5462-71-5

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzeneacetic acid,4-cyano-

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 4-CYANOPHENYLACETIC ACID

Cas:5462-71-5

Min.Order:100 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-Cyanophenylacetic acid manufacturer

Cas:5462-71-5

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

5462-71-5 4-CYANOPHENYLACETIC ACID

Cas:5462-71-5

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

4-Cyanophenylaceticacid

Cas:5462-71-5

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Product Name: 4-CYANOPHENYLACETIC ACID Synonyms: 4-CYANOPHENYLACETIC ACID;2-(4-CYANOPHENYL)ACETIC ACID;2-(4-cyanophenyl)ethanoic acid;4-Cyanobenzeneacetic acid;4-Cyanophenylacetic acid ,98%;Benzeneacetic acid, 4-cyano-;4-Cyanophenylacetic acid

4-CYANOPHENYLACETIC ACID

Cas:5462-71-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

2-(4-Cyanophenyl)acetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Manufacturers

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ 4-Cyanophenylacetic acid /Manufacturer in China

Cas:5462-71-5

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-cyanophenylacetic acid cas no. 5462-71-5 98%

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Greenutra Resource Inc

4-Cyanophenylacetic acidAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air

4-Cyanophenylacetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-Cyanophenylacetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Other

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-(4-Cyanophenyl)acetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-Cyanobenzeneacetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 2-(4-Cyanophenyl)acetic acid 100g

Cas:5462-71-5

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

4-Cyanophenylacetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

4-CYANOPHENYLACETIC ACID

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzeneacetic acid,4-cyano-

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

4-Cyanophenylacetic acid CAS No.5462-71-5

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

4-CYANOPHENYLACETIC ACID

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary a

4-Cyanophenylacetic acid

Cas:5462-71-5

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Synthetic route

potassium ferrocyanide

potassium ferrocyanide

2-(4-bromophenyl)-acetic acid
1878-68-8

2-(4-bromophenyl)-acetic acid

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With 2C6H15N*C49H47Cl2Fe2N2O8P2PdS2; potassium carbonate In 1,4-dioxane; water at 100℃; Inert atmosphere;89%
carbon dioxide
124-38-9

carbon dioxide

1-(4-cyanophenyl)-N,N,N-trimethylmethanaminium trifluoromethanesulfonate

1-(4-cyanophenyl)-N,N,N-trimethylmethanaminium trifluoromethanesulfonate

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; sodium carbonate; caesium carbonate In N,N-dimethyl-formamide at 25 - 30℃; for 26h; Schlenk technique; Glovebox; Sealed tube; Irradiation;84%
4-aminophenylacetic acid
1197-55-3

4-aminophenylacetic acid

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
Stage #1: 4-aminophenylacetic acid With hydrogenchloride; sodium nitrite In water; acetic acid at 0 - 40℃; for 0.75h;
Stage #2: With sodium cyanide; copper(l) cyanide In water; acetic acid at 0 - 5℃; for 3.66667h;
78.9%
carbon monoxide
201230-82-2

carbon monoxide

4-cyanobenzyl bromide
17201-43-3

4-cyanobenzyl bromide

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With palladium hydroxide, 20 wt% on carbon; tetrabutylammomium bromide; water In tetrahydrofuran at 110℃; under 7500.75 Torr; for 4h; Sealed tube; Autoclave;76%
With cobalt(II) pyridine-2-carboxylate; palladium diacetate; sodium hydroxide In methanol at 150℃; under 11251.1 Torr; for 6h; Reagent/catalyst; Autoclave;54%
4-(cyanomethyl)benzonitrile
876-31-3

4-(cyanomethyl)benzonitrile

A

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

B

4-(cyanomethyl)benzoic acid
50685-26-2

4-(cyanomethyl)benzoic acid

Conditions
ConditionsYield
With water for 24h; Rhodococcus rhodochrous AJ270;A 65%
B 16%
With potassium phosphate buffer; Rhodococcus sp. AJ270 at 30℃; for 24h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
carbon dioxide
124-38-9

carbon dioxide

4-cyanobenzyl 2-methoxyacetate
507250-20-6

4-cyanobenzyl 2-methoxyacetate

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With manganese; dichlorobis(trimethylphosphine)nickel In N,N-dimethyl-formamide at 100℃; under 760.051 Torr; for 24h; Schlenk technique;64%
4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzonitrile
79149-49-8

4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzonitrile

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane for 12h; Heating;61%
carbon dioxide
124-38-9

carbon dioxide

4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzonitrile

4-((4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methyl)benzonitrile

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With potassium ethoxide In 1,4-dioxane at 100℃; for 24h;60%
carbon monoxide
201230-82-2

carbon monoxide

4-cyanobenzyl bromide
17201-43-3

4-cyanobenzyl bromide

A

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

B

2-(4-carbamoylphenyl)-acetic acid
2393-28-4

2-(4-carbamoylphenyl)-acetic acid

Conditions
ConditionsYield
With chloro(1,5-cyclooctadiene)rhodium(I) dimer; potassium iodide In formic acid at 60℃; under 760 Torr; for 18h; Carbonylation;A 51%
B n/a
4-(cyanomethyl)benzonitrile
876-31-3

4-(cyanomethyl)benzonitrile

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With hydrogenchloride for 0.0666667h; Heating;46%
With hydrogenchloride
With hydrogenchloride In methanol; acetic acid; ethyl acetate
dicyanozinc
557-21-1

dicyanozinc

2-(4-bromophenyl)-acetic acid
1878-68-8

2-(4-bromophenyl)-acetic acid

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With tetrakis(triphenylphosphine) palladium(0) In N,N-dimethyl-formamide at 80℃; for 18h;42%
4-aminophenylacetic acid
1197-55-3

4-aminophenylacetic acid

potassium cyanide
151-50-8

potassium cyanide

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With hydrogenchloride; water; copper(II) sulfate Diazotization.Erwaermen des Reaktionsgemisches;
methanol
67-56-1

methanol

1-Naphthylmethyl 4-cyanophenylacetate
143659-31-8

1-Naphthylmethyl 4-cyanophenylacetate

A

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

B

1-(methoxymethyl)naphthalene
5903-23-1

1-(methoxymethyl)naphthalene

C

4-(2-Naphthalen-1-yl-ethyl)-benzonitrile

4-(2-Naphthalen-1-yl-ethyl)-benzonitrile

Conditions
ConditionsYield
Irradiation;A n/a
B 77 % Chromat.
C 24 % Chromat.
Rate constant; Quantum yield; Irradiation; rate of decarboxylation k(CO2);A n/a
B 77 % Chromat.
C 24 % Chromat.
4-cyanophenylketene
58784-39-7

4-cyanophenylketene

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With water at 26℃; Rate constant;
2,2-dibromo-1-(4-cyanophenyl)ethene
131356-52-0

2,2-dibromo-1-(4-cyanophenyl)ethene

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 90 percent / H2O / ethyl acetate / 0.3 h / 20 °C
2: 61 percent / aq. HCl / dioxane / 12 h / Heating
View Scheme
4-cyanobenzaldehyde
105-07-7

4-cyanobenzaldehyde

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 73 percent / PPh3 / CH2Cl2 / 1 h / 0 °C
2: 90 percent / H2O / ethyl acetate / 0.3 h / 20 °C
3: 61 percent / aq. HCl / dioxane / 12 h / Heating
View Scheme
4-cyanobenzyl chloride
874-86-2

4-cyanobenzyl chloride

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous alcohol
2: fuming hydrochloric acid
View Scheme
4-(2-hydroxyethyl)benzonitrile
69395-13-7

4-(2-hydroxyethyl)benzonitrile

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With Jones reagent In acetone at 20℃; for 0.166667h;
With sodium periodate; ruthenium trichloride In tetrachloromethane; water; acetonitrile at 20℃;
With Jones reagent In acetone at 20℃; for 0.166667h;
carbon dioxide
124-38-9

carbon dioxide

p-cyanobenzyl methyl carbonate
1253037-52-3

p-cyanobenzyl methyl carbonate

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With tetrabutylammonium tetrafluoroborate In acetonitrile at 0℃; under 760.051 Torr; Electrochemical reaction;
carbon dioxide
124-38-9

carbon dioxide

p-cyanobenzyl ethyl carbonate

p-cyanobenzyl ethyl carbonate

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With tetrabutylammonium tetrafluoroborate In acetonitrile at 0℃; under 760.051 Torr; Electrochemical reaction;
4-Cyanobenzyl alcohol
874-89-5

4-Cyanobenzyl alcohol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 12 h / 20 °C
2: manganese; dichlorobis(trimethylphosphine)nickel / N,N-dimethyl-formamide / 24 h / 100 °C / 760.05 Torr / Schlenk technique
View Scheme
tert-butyl acetylenyl ether
89489-28-1

tert-butyl acetylenyl ether

4-iodobenzonitrile
3058-39-7

4-iodobenzonitrile

A

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

B

tert-butyl 4-nitrilephenylacetylenyl ether

tert-butyl 4-nitrilephenylacetylenyl ether

C

C16H17NO

C16H17NO

D

tert-butyl 2-(4-cyanophenyl)acetate

tert-butyl 2-(4-cyanophenyl)acetate

Conditions
ConditionsYield
With copper(l) iodide; tetrakis(triphenylphosphine) palladium(0); triethylamine at 80℃; Reagent/catalyst; Sonogashira Cross-Coupling; Inert atmosphere;A n/a
B 54 %Spectr.
C n/a
D n/a
carbon dioxide
124-38-9

carbon dioxide

4-Cyanobenzyl alcohol
874-89-5

4-Cyanobenzyl alcohol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 0℃; Solvent; Temperature; Electrochemical reaction;78 %Spectr.
4-cyanophenylacetylene
3032-92-6

4-cyanophenylacetylene

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
Stage #1: 4-cyanophenylacetylene With n-butyllithium In tetrahydrofuran at -78℃; for 1h;
Stage #2: With 2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane In tetrahydrofuran for 2h;
Stage #3: With oxone In acetone at 50℃; for 12h;
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere
1.2: 2 h / -78 °C / Inert atmosphere
2.1: oxone||potassium monopersulfate triple salt; water / acetone / 12 h / 50 °C / Inert atmosphere
View Scheme
C14H16O2BCN

C14H16O2BCN

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With oxone||potassium monopersulfate triple salt; water In acetone at 50℃; for 12h; Inert atmosphere;516 mg
carbon dioxide
124-38-9

carbon dioxide

4-cyanobenzyl bromide
17201-43-3

4-cyanobenzyl bromide

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Conditions
ConditionsYield
With N,N,N,N-tetraethylammonium tetrafluoroborate In acetonitrile Electrochemical reaction; Inert atmosphere;
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

N4-methyl-[1,1'-biphenyl]-3,4-diamine
236417-77-9

N4-methyl-[1,1'-biphenyl]-3,4-diamine

4-[(5-phenyl-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile

4-[(5-phenyl-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In tetrahydrofuran100%
ethyl 3-[1-(3-amino-4-methylamino-benzyl)-1H-benzimidazol-2-yl]-propionate

ethyl 3-[1-(3-amino-4-methylamino-benzyl)-1H-benzimidazol-2-yl]-propionate

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-[(5-(2-ethoxycarbonyl-ethyl-benzimidazol-1-yl)methyl-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile

4-[(5-(2-ethoxycarbonyl-ethyl-benzimidazol-1-yl)methyl-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In tetrahydrofuran100%
methanol
67-56-1

methanol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

methyl 4-cyanobenzeneacetate
52798-01-3

methyl 4-cyanobenzeneacetate

Conditions
ConditionsYield
With thionyl chloride for 12h; Cooling with ice;100%
With thionyl chloride at 20℃; for 23h; Cooling with ice; Inert atmosphere;99%
With sulfuric acid at 75℃; for 4h;98%
With thionyl chloride at 0 - 20℃; for 21.5h;
With thionyl chloride for 3h; Reagent/catalyst; Reflux;
morpholine
110-91-8

morpholine

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-[2-(morpholin-4-yl)-2-oxoethyl]benzonitrile
79149-51-2

4-[2-(morpholin-4-yl)-2-oxoethyl]benzonitrile

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 1h;99%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

methyl (2R)-2-amino-2-[4-(2-methylpentyloxy)phenyl]acetate hydrochloride

methyl (2R)-2-amino-2-[4-(2-methylpentyloxy)phenyl]acetate hydrochloride

methyl (2R)-2-[4-(2-methylpentyloxy)phenyl]-2-[2-(4-cyanophenyl)acetamido]acetate

methyl (2R)-2-[4-(2-methylpentyloxy)phenyl]-2-[2-(4-cyanophenyl)acetamido]acetate

Conditions
ConditionsYield
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine In acetonitrile at 20℃; for 5h; Inert atmosphere;98%
(E/Z)-2-buten-1-ol
6117-91-5

(E/Z)-2-buten-1-ol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

C13H13NO2

C13H13NO2

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;95%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

2-(4-(aminomethyl)phenyl)acetic acid
1200-05-1

2-(4-(aminomethyl)phenyl)acetic acid

Conditions
ConditionsYield
With ammonium hydroxide; hydrogen In water at 20℃; for 48h;94%
2-thiophenethanol
5402-55-1

2-thiophenethanol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

C15H13NO2S

C15H13NO2S

Conditions
ConditionsYield
Stage #1: 4-cyanophenylacetic acid With dmap; dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 0.166667h;
Stage #2: 2-thiophenethanol In dichloromethane at 20℃;
93%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

(4-Cyan-2-nitrophenyl)essigsaeure
90178-58-8

(4-Cyan-2-nitrophenyl)essigsaeure

Conditions
ConditionsYield
With sulfuric acid; nitric acid at -9 - 15℃; for 2h;92%
With sulfuric acid; nitric acid at 5 - 10℃; for 2h;68%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-bromo-2-iodoaniline
66416-72-6

4-bromo-2-iodoaniline

N-(4-bromo-2-iodophenyl)-2-(4-cyanophenyl)acetamide

N-(4-bromo-2-iodophenyl)-2-(4-cyanophenyl)acetamide

Conditions
ConditionsYield
With triethylamine; HATU In dichloromethane at 20℃; for 22h;92%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

di-tert-butyl-diazodicarboxylate
870-50-8

di-tert-butyl-diazodicarboxylate

di-tert-butyl 1-(4-cyanobenzyl)hydrazine-1,2-dicarboxylate

di-tert-butyl 1-(4-cyanobenzyl)hydrazine-1,2-dicarboxylate

Conditions
ConditionsYield
With iron(III) sulfate; bis[(2-pyridyl)methyl]amine In 1,2-dichloro-ethane at 20℃; for 24h; Inert atmosphere; Sealed tube; Irradiation;92%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-chlorobenzoylmethyl bromide
536-38-9

4-chlorobenzoylmethyl bromide

4-(4-(4-chlorophenyl)-2-oxo-2,5-dihydrofuran-3-yl)benzonitrile
1034414-78-2

4-(4-(4-chlorophenyl)-2-oxo-2,5-dihydrofuran-3-yl)benzonitrile

Conditions
ConditionsYield
Stage #1: 4-cyanophenylacetic acid With potassium tert-butylate In N,N-dimethyl-formamide at -15 - -10℃;
Stage #2: 4-chlorobenzoylmethyl bromide In N,N-dimethyl-formamide at -10 - 0℃; for 1.5h;
Stage #3: With triethylamine In N,N-dimethyl-formamide at 0 - 20℃; for 1.5h;
91%
ethanol
64-17-5

ethanol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

ethyl 4-cyanophenylacetate
1528-41-2

ethyl 4-cyanophenylacetate

Conditions
ConditionsYield
With hydrogenchloride for 3h; Reflux;89%
With sulfuric acid for 2h; Inert atmosphere; Reflux;88%
With sulfuric acid at 80℃; Inert atmosphere; Schlenk technique;85%
With sulfuric acid for 2h; Inert atmosphere; Reflux;
With sulfuric acid for 24h; Reflux;
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

2-amino-N-(3-cyanobenzyl)acetamide hydrochloride

2-amino-N-(3-cyanobenzyl)acetamide hydrochloride

N-(3-cyanobenzyl)-2-(2-(4-cyanophenyl)acetamido)acetamide

N-(3-cyanobenzyl)-2-(2-(4-cyanophenyl)acetamido)acetamide

Conditions
ConditionsYield
Stage #1: 2-amino-N-(3-cyanobenzyl)acetamide hydrochloride With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: 4-cyanophenylacetic acid In N,N-dimethyl-formamide at 20℃;
88%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

2-octenol
22104-78-5

2-octenol

C17H21NO2

C17H21NO2

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;88%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

terephthalonitrile
623-26-7

terephthalonitrile

Conditions
ConditionsYield
With iron(III) trifluoromethanesulfonate; sodium nitrite In dimethyl sulfoxide at 50℃; for 10h; Inert atmosphere; Sealed tube;82%
With oxygen; copper(II) trifluoroacetate; urea In dimethyl sulfoxide at 110℃; for 24h; Green chemistry;66%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-(carboxymethyl)benzoic acid
501-89-3

4-(carboxymethyl)benzoic acid

Conditions
ConditionsYield
With water; potassium hydroxide at 110℃; for 4h;81%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

2-(4-cyanobenzylamino)-2-oxoethanaminium chloride

2-(4-cyanobenzylamino)-2-oxoethanaminium chloride

N-(4-cyanobenzyl)-2-(2-(4-cyanophenyl)acetamido)acetamide

N-(4-cyanobenzyl)-2-(2-(4-cyanophenyl)acetamido)acetamide

Conditions
ConditionsYield
Stage #1: 2-(4-cyanobenzylamino)-2-oxoethanaminium chloride With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 0.25h;
Stage #2: 4-cyanophenylacetic acid In N,N-dimethyl-formamide at 20℃;
81%
2,4-hexadiene-1-ol
111-28-4

2,4-hexadiene-1-ol

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

C15H15NO2

C15H15NO2

Conditions
ConditionsYield
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; Inert atmosphere;81%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

N1-methyl-4-nitrobenzene-1,2-diamine
41939-61-1

N1-methyl-4-nitrobenzene-1,2-diamine

2-(4-cyano-phenyl)-N-(2-methylamino-5-nitro-phenyl)acetamide
850464-49-2

2-(4-cyano-phenyl)-N-(2-methylamino-5-nitro-phenyl)acetamide

Conditions
ConditionsYield
Stage #1: 4-cyanophenylacetic acid With 1,1'-carbonyldiimidazole In tetrahydrofuran at 50℃; for 0.5h;
Stage #2: N1-methyl-4-nitrobenzene-1,2-diamine In tetrahydrofuran at 50℃; for 2h; Further stages.;
79%
pyrrolidine
123-75-1

pyrrolidine

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzonitrile
79149-49-8

4-(2-oxo-2-(pyrrolidin-1-yl)ethyl)benzonitrile

Conditions
ConditionsYield
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane79%
Stage #1: 4-cyanophenylacetic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 20℃; for 0.0833333h;
Stage #2: pyrrolidine In dichloromethane
79%
Stage #1: 4-cyanophenylacetic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane for 0.0833333h;
Stage #2: pyrrolidine In dichloromethane
79%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

(2-aminophenyl)(phenyl)methanone
2835-77-0

(2-aminophenyl)(phenyl)methanone

4-(4-phenylquinazolin-2-yl)benzonitrile

4-(4-phenylquinazolin-2-yl)benzonitrile

Conditions
ConditionsYield
With ammonium acetate; oxygen; copper diacetate In 1-methyl-pyrrolidin-2-one at 120℃; under 760.051 Torr; for 20h;75%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

(5H-imidazo[5,1-a]isoindol-5-yl)methanamine

(5H-imidazo[5,1-a]isoindol-5-yl)methanamine

C20H16N4O

C20H16N4O

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 10 - 35℃;75%
4-(cyclohexylcarbonyl)-2-amino-N-methyl-aniline

4-(cyclohexylcarbonyl)-2-amino-N-methyl-aniline

4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

4-[(5-cyclohexylcarbonyl-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile

4-[(5-cyclohexylcarbonyl-1-methyl-1H-benzimidazol-2-yl)-methyl]-benzonitrile

Conditions
ConditionsYield
With 1,1'-carbonyldiimidazole In tetrahydrofuran74%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

formamidine acetic acid
3473-63-0

formamidine acetic acid

2-(4-(1,2,4,5-tetrazin-3-yl)phenyl)acetic acid
1380500-92-4

2-(4-(1,2,4,5-tetrazin-3-yl)phenyl)acetic acid

Conditions
ConditionsYield
Stage #1: 4-cyanophenylacetic acid; formamidine acetic acid With nickel(II) triflate; hydrazine at 30℃; for 24h; Microwave irradiation;
Stage #2: With hydrogenchloride; sodium nitrite In water at 20℃; pH=3;
74%
4-cyanophenylacetic acid
5462-71-5

4-cyanophenylacetic acid

Grushin’s reagent

Grushin’s reagent

4-(2,2,2-trifluoroethyl)-benzonitrile

4-(2,2,2-trifluoroethyl)-benzonitrile

Conditions
ConditionsYield
Stage #1: Grushin’s reagent With dimethyl zinc(II) In acetonitrile at 20℃; for 0.5h; Inert atmosphere; Schlenk technique;
Stage #2: 4-cyanophenylacetic acid With dipotassium peroxodisulfate; silver nitrate In water; acetonitrile at 40℃; for 10h; Inert atmosphere; Schlenk technique;
74%

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