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Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 5A-PREGNANE-3-20-DIONE-ALLO 5g

Cas:566-65-4

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for 5-alpha-Dihydroprogesterone Cas 566-65-4 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or almost white crystalline powder Storage:Cool dry plac

Factory supply 5-alpha-Dihydroprogesterone Cas 566-65-4 with high quality and best price

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $500.0 / 545.0

Type:Trading Company

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality 5α-Pregnane-3,20-dione

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

CHemwill -- 5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 5-alpha-Dihydroprogesterone Synonyms: ALLOPREGNANE-3,20-DIONE;ALLOPREGNAN-3,20-DIONE;ALLOPREGNANDIONE;(5S,8R,9S,10S,13S,14S,17S)-17-ACETYL-10,13-DIMETHYL-HEXADECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE;5 A-PREGNANE-3 20-DION

566-65-4 5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 566-65-4 with best quality

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Pregnane-3,20-dione, (5alpha)- 566-65-4

Cas:566-65-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

5-alpha-Dihydroprogesterone CAS:566-65-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

5-alpha-Dihydroprogesterone CAS:566-65-4

Cas:566-65-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pregnane-3,20-dione, (5alpha)-

Cas:566-65-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5Alpha -Dihydroprogesterone

Cas:566-65-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

superior quality moderate price & quick delivery Appearance:powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:1kg/bag, 1kg/drum or 25kg/drum or as per your request. Application:moderate price & quick del

Pregnane-3,20-dione, (5alpha)-

Cas:566-65-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

PREGNANE-3,20-DIONE CAS NO 566-65-4

Cas:566-65-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pregnane-3,20-dione, (5alpha)-

Cas:566-65-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 5Alpha -Dihydroprogesterone

Cas:566-65-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen

Pregnane-3,20-dione, 5-alpha-Dihydroprogesterone CAS NO.566-65-4

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $2.0 / 6.0

Type:Trading Company

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity 5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Pregnane-3,20-dione

Cas:566-65-4

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Pregnane-3,20-dione, (5alpha)-

Cas:566-65-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

5alpha-Pregnane-3,20-dione

Cas:566-65-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

5-alpha-Dihydroprogesterone

Cas:566-65-4

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Pregnane-3,20-dlone

Cas:566-65-4

Min.Order:0

Negotiable

Type:Other

inquiry

Lonwin Chemical Group Limited

Shanghai Lonwin Chemical company is a subsidiary of Lonwin Industry Group Limited, was established in 2011 and is headquartered in Shanghai, adjacent to China National Convention and Exhibition Center and Hongqiao transportation hub.Lonwinchem is

Best price 5Alpha -Dihydroprogesterone 566-65-4

Cas:566-65-4

Min.Order:100 Kilogram

FOB Price: $100.0 / 150.0

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Allopregnandione

Cas:566-65-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Pregnane-3,20-Dione

Cas:566-65-4

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(20R)-5α-Pregnandiol-(3β.20)
516-53-0

(20R)-5α-Pregnandiol-(3β.20)

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With Jones reagent In acetone at 10℃;96%
With chromium(VI) oxide; acetic acid
3β-methoxy-5α-pregnane-20-one
7680-01-5

3β-methoxy-5α-pregnane-20-one

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With 3,3-dimethyldioxirane In acetone for 18h; Ambient temperature;95%
5α-pregnanedione-(3,20)-dioxime
6170-12-3

5α-pregnanedione-(3,20)-dioxime

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With acetyl chloride; sodium nitrite In dichloromethane at 20℃;90%
Progesterone
57-83-0

Progesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

20-hydroxy-Δ4-progest-3-one
15114-79-1

20-hydroxy-Δ4-progest-3-one

Conditions
ConditionsYield
With N,N,N,N,N,N-hexamethylphosphoric triamide; methylcopper; diisobutylaluminium hydride In tetrahydrofuran; diethyl ether; hexane at -50℃; for 2h;A 84%
B 5.9%
1-((3S,5S,8R,9S,10S,13S,14S,17S)-3-Benzyloxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-ethanone

1-((3S,5S,8R,9S,10S,13S,14S,17S)-3-Benzyloxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-ethanone

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With 3,3-dimethyldioxirane In acetone for 18h; Ambient temperature;82%
isopregnanolone
516-55-2

isopregnanolone

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With sodium hypochlorite; acetic acid; sodium bromide In tetrahydrofuran at 20 - 40℃; for 2h;81%
With sodium hypochlorite; sodium bromide In water; acetic acid at 20℃; for 2h;79%
With chromium(VI) oxide; acetic acid
Progesterone
57-83-0

Progesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

pregnanedione
128-23-4

pregnanedione

C

allopregnanolone
40135-22-6

allopregnanolone

D

3-hydroxy-5β-pregnan-20-one
4320-08-5

3-hydroxy-5β-pregnan-20-one

Conditions
ConditionsYield
With hydrogen; Cu/Al2O3 In toluene at 60℃; under 760 Torr;A 14%
B 49%
C 2%
D 8%
Progesterone
57-83-0

Progesterone

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
In ethanol at 24 - 26℃; for 96h; Penicillium decumbens ATCC 10436, potato dextrose broth;45%
With Chlorella vulgaris C211/8k; 4,4'-butylidenebis(6-tert-butyl-m-cresol) at 20℃; for 360h; Reduction; illumination;17.3%
With Penicillium digitatum MRC 500787; MYB medium (malt extract 2percent, glucose 1percent, bacteriological peptone 1percent, yeast extract 0.3percent) In N,N-dimethyl-formamide at 24℃; for 120h;12.3%
dihydrocholesterone
566-88-1

dihydrocholesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

5α-cholestane-3,11-dione
69483-56-3

5α-cholestane-3,11-dione

C

5α-cholestane-3,6-dione
2243-09-6

5α-cholestane-3,6-dione

D

3,7-dioxo-5α-cholestane
13400-67-4

3,7-dioxo-5α-cholestane

Conditions
ConditionsYield
With pyridine; oxygen; acetic acid; zinc; iron In water for 5h; Ambient temperature; Gif system; Further byproducts given;A 4.6%
B 1.1%
C 4.1%
D 3.8%
dihydrocholesterone
566-88-1

dihydrocholesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

5α-cholestane-3,6-dione
2243-09-6

5α-cholestane-3,6-dione

C

3,7-dioxo-5α-cholestane
13400-67-4

3,7-dioxo-5α-cholestane

D

(5S,8R,9S,10S,13S,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-tetradecahydro-cyclopenta[a]phenanthrene-3,16-dione
108393-74-4

(5S,8R,9S,10S,13S,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-tetradecahydro-cyclopenta[a]phenanthrene-3,16-dione

Conditions
ConditionsYield
With pyridine; oxygen; acetic acid; zinc; iron In water for 5h; Ambient temperature; Gif system; Further byproducts given;A 4.6%
B 4.1%
C 3.8%
D 2.1%
dihydrocholesterone
566-88-1

dihydrocholesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

5α-cholestane-3,6-dione
2243-09-6

5α-cholestane-3,6-dione

C

3,7-dioxo-5α-cholestane
13400-67-4

3,7-dioxo-5α-cholestane

D

(5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-tetradecahydro-cyclopenta[a]phenanthrene-3,12-dione
41882-89-7

(5S,8R,9S,10S,13R,14S,17R)-17-((R)-1,5-Dimethyl-hexyl)-10,13-dimethyl-tetradecahydro-cyclopenta[a]phenanthrene-3,12-dione

Conditions
ConditionsYield
With pyridine; oxygen; acetic acid; zinc; iron In water for 5h; Ambient temperature; Gif system; Further byproducts given;A 4.6%
B 4.1%
C 3.8%
D 1%
dihydrocholesterone
566-88-1

dihydrocholesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

5α-cholestane-3,6-dione
2243-09-6

5α-cholestane-3,6-dione

C

3,7-dioxo-5α-cholestane
13400-67-4

3,7-dioxo-5α-cholestane

D

5α,14α-cholestane-3,15-dione
73389-50-1

5α,14α-cholestane-3,15-dione

Conditions
ConditionsYield
With pyridine; oxygen; acetic acid; zinc; iron In water for 5h; Ambient temperature; Gif system; Further byproducts given;A 4.6%
B 4.1%
C 3.8%
D 3.3%
methanol
67-56-1

methanol

(5α,17βH)-pregnane-3,20-dione
51154-65-5

(5α,17βH)-pregnane-3,20-dione

sodium methylate
124-41-4

sodium methylate

dihydroprogesterone
566-65-4

dihydroprogesterone

1-(3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-ethanone
145-13-1, 566-63-2, 19037-28-6, 38372-24-6

1-(3-Hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-ethanone

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With palladium on activated charcoal Hydrogenation.anschliessende Oxidation mit CrO3;
Progesterone
57-83-0

Progesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

pregnanedione
128-23-4

pregnanedione

Conditions
ConditionsYield
With hydrogen; palladium In pyridine at 25℃; under 760 Torr; Rate constant; selectivity to 5β compound;
With hydrogen bromide; hydrogen; palladium In tetrahydrofuran at 25℃; under 760 Torr; Rate constant; selectivity to 5β compound;
With acetic acid; platinum Hydrogenation.Behandlung des Reaktionsprodukts mit CrO3 in Essigsaeure bei 15-20grad;
Pregnenolone
145-13-1

Pregnenolone

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With acetic acid; platinum Hydrogenation.anschliessende Behandlung mit CrO3 in Essigsaeure;
Multi-step reaction with 2 steps
1: 90 percent / H2 / Pd/C / tetrahydrofuran; acetic acid / 8 h / 50 - 60 °C / 3102.89 Torr
2: 79 percent / NaOCl; NaBr / acetic acid; H2O / 2 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / ethanol / 12 h / 40 °C / 2327.23 Torr
2: Dess-Martin periodane / dichloromethane / 3 h / 0 - 25 °C
View Scheme
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen; acetic acid / tetrahydrofuran / 60 °C / 3102.97 Torr
2: acetic acid; sodium bromide; sodium hypochlorite / tetrahydrofuran / 2 h / 20 - 40 °C
View Scheme
Pregnenolone acetate
1778-02-5

Pregnenolone acetate

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With acetic acid; platinum Hydrogenation.Erhitzen des Hydrierungsprodukts mit methanol. KOH und Behandeln des Reaktionsprodukts mit CrO3 in Essigsaeure bei 20grad;
Multi-step reaction with 3 steps
1: H2 / 10 percent Pd/C
View Scheme
isopregnanolone
516-55-2

isopregnanolone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

20-oxo-2,3-seco-5α-pregnanedioic acid-(2,3)
26654-59-1

20-oxo-2,3-seco-5α-pregnanedioic acid-(2,3)

Conditions
ConditionsYield
With chromium(VI) oxide; acetic acid
5α-pregnan-3β,20α-diol
566-56-3

5α-pregnan-3β,20α-diol

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With chromium(VI) oxide; acetic acid
5α-pregnane-3α,20α-diol
566-58-5

5α-pregnane-3α,20α-diol

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With chromium(VI) oxide; acetic acid
tetrahydroprogesterone
516-54-1

tetrahydroprogesterone

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With chromium(VI) oxide; acetic acid
With NAD:3α-hydroxy-5α-pregnane-20-one oxidoreductase; NAD at 37℃;
With oxygen; sodium acetate In water; Diethyl carbonate at 100℃; under 37503.8 Torr; for 4h; Autoclave;
5α-H-pregn-16-ene-3,20-dione
13164-11-9

5α-H-pregn-16-ene-3,20-dione

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With Pd-BaSO4; diethyl ether Hydrogenation;
With Pd-BaSO4; ethanol Hydrogenation;
With acetic acid; zinc at 100℃;
Progesterone
57-83-0

Progesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

pregnanedione
128-23-4

pregnanedione

C

Androstenedione
63-05-8

Androstenedione

D

17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

Conditions
ConditionsYield
With D-glucose; Dulbecco phosphate buffer at 37℃; for 22h; Product distribution; metabolism after incubation of blastoderms of fertilized eggs of White Leghorn hens;
Progesterone
57-83-0

Progesterone

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

isopregnanolone
516-55-2

isopregnanolone

C

(20S)-20-hydroxypregn-4-en-3-one
145-14-2

(20S)-20-hydroxypregn-4-en-3-one

D

5α-pregnan-3β,20α-diol
566-56-3

5α-pregnan-3β,20α-diol

Conditions
ConditionsYield
With Tris buffer at 37℃; for 2h; Product distribution; metabolism in human endometrial adenocarcinoma cells (HEC-1 line), 14C- and 3H-labeled in dependence on time;
Pregnenolone
145-13-1

Pregnenolone

A

Progesterone
57-83-0

Progesterone

B

dihydroprogesterone
566-65-4

dihydroprogesterone

C

pregnanedione
128-23-4

pregnanedione

Conditions
ConditionsYield
With D-glucose; Dulbecco phosphate buffer at 37℃; for 22h; Product distribution; metabolism after incubation of blastoderms of fertilized eggs of White Leghorn hens;
2α-(1-pyridinio)-5α-pregnane-3,20-dione bromide

2α-(1-pyridinio)-5α-pregnane-3,20-dione bromide

A

Progesterone
57-83-0

Progesterone

B

dihydroprogesterone
566-65-4

dihydroprogesterone

C

pregnanedione
128-23-4

pregnanedione

D

(5S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
65556-93-6

(5S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

E

(5R,8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

(5R,8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With pyridine at 280℃; under 1520 Torr; Product distribution; pyrolysis in GLC vaporizer, various additives (without, 2,4,6-collidine), other temperature (250 deg C);A 51.5 % Chromat.
B 11.9 % Chromat.
C 2.2 % Chromat.
D 26.4 % Chromat.
E 3.1 % Chromat.
1-((8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-ylidene)-pyrrolidinium; perchlorate

1-((8S,9S,10R,13S,14S,17S)-17-Acetyl-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-ylidene)-pyrrolidinium; perchlorate

A

dihydroprogesterone
566-65-4

dihydroprogesterone

B

pregnanedione
128-23-4

pregnanedione

Conditions
ConditionsYield
With 1-Benzyl-1,4-dihydronicotinamide; water 1.) acetonitrile, 40 h, reflux 2.) acetonitrile, reflux, 1 h; Multistep reaction. Yields of byproduct given;
With 1-Benzyl-1,4-dihydronicotinamide; water 1.) acetonitrile, 40 h, reflux 2.) acetonitrile, reflux, 1 h; Multistep reaction;
3-hydroxy-pregna-5,16-dion-20-one

3-hydroxy-pregna-5,16-dion-20-one

dihydroprogesterone
566-65-4

dihydroprogesterone

Conditions
ConditionsYield
With palladium on activated charcoal Hydrogenation.anschliessende Oxidation mit CrO3;
isopregnanolone
516-55-2

isopregnanolone

acetic acid
64-19-7

acetic acid

CrO3

CrO3

dihydroprogesterone
566-65-4

dihydroprogesterone

dihydroprogesterone
566-65-4

dihydroprogesterone

<2H9>trimethylsulphoxonium iodide
23726-00-3

<2H9>trimethylsulphoxonium iodide

1-((3R,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxiran]-17-yl-3',3'-d2)ethan-1-one

1-((3R,5S,8R,9S,10S,13S,14S,17S)-10,13-dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2'-oxiran]-17-yl-3',3'-d2)ethan-1-one

Conditions
ConditionsYield
Stage #1: <2H9>trimethylsulphoxonium iodide With potassium tert-butylate In dimethylsulfoxide-d6 at 60℃; for 1h; Inert atmosphere;
Stage #2: dihydroprogesterone In dimethylsulfoxide-d6 at 20℃;
99%
2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane
7381-30-8

2,2,7,7-tetramethyl-3,6-dioxa-2,7-disilaoctane

dihydroprogesterone
566-65-4

dihydroprogesterone

C23H36O3
98632-74-7

C23H36O3

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at -78℃; for 6h;94%
dihydroprogesterone
566-65-4

dihydroprogesterone

trimethylsulfoxonium iodide
1774-47-6

trimethylsulfoxonium iodide

1-((2’R,8R,10S,13S,14S,17S)-10,13-dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2’-oxiran]-17-yl)ethanone
148256-45-5

1-((2’R,8R,10S,13S,14S,17S)-10,13-dimethylhexadecahydrospiro[cyclopenta[a]phenanthrene-3,2’-oxiran]-17-yl)ethanone

Conditions
ConditionsYield
Stage #1: trimethylsulfoxonium iodide In dimethyl sulfoxide at 65℃; for 2h; Inert atmosphere;
Stage #2: dihydroprogesterone In dimethyl sulfoxide at 20 - 35℃; for 2h; Inert atmosphere;
94%
Stage #1: trimethylsulfoxonium iodide With potassium tert-butylate In dimethyl sulfoxide at 60℃; for 1h; Inert atmosphere;
Stage #2: dihydroprogesterone In dimethyl sulfoxide at 20℃;
87%
With potassium tert-butylate In dimethyl sulfoxide at 20℃; for 5h;75%
With sodium hydride 1.) DMSO, RT, 1 h, 2.) DMSO, 2.5 h; Yield given. Multistep reaction;
dihydroprogesterone
566-65-4

dihydroprogesterone

anti-3-oxime of 5α-pregnane-3,20-dione
6750-73-8

anti-3-oxime of 5α-pregnane-3,20-dione

Conditions
ConditionsYield
With pyridine; hydroxylamine hydrochloride at 0℃; for 3h;92%
dihydroprogesterone
566-65-4

dihydroprogesterone

methylmagnesium chloride
676-58-4

methylmagnesium chloride

ganaxolone
38398-32-2

ganaxolone

Conditions
ConditionsYield
Stage #1: methylmagnesium chloride With iron(III) chloride; lithium chloride In tetrahydrofuran at -35℃;
Stage #2: dihydroprogesterone In tetrahydrofuran at -35 - -18℃; for 3h;
Stage #3: With hydrogenchloride; water In tetrahydrofuran at 25℃; Product distribution / selectivity;
91%
dihydroprogesterone
566-65-4

dihydroprogesterone

2R-(+)-2α-fluoro-5α-pregnane-3,20-dione

2R-(+)-2α-fluoro-5α-pregnane-3,20-dione

Conditions
ConditionsYield
With ent-9-amino(9-deoxy)epi-hydroquinine; sodium carbonate; N-fluorobis(benzenesulfon)imide; trichloroacetic acid In tetrahydrofuran; dichloromethane at -10℃; for 48h; Inert atmosphere; optical yield given as %de; diastereoselective reaction;91%
dihydroprogesterone
566-65-4

dihydroprogesterone

allopregnan-20-one
848-62-4

allopregnan-20-one

Conditions
ConditionsYield
With zinc In acetic acid at 15℃; for 0.25h; ultrasonic irradiation;90%
With hydrogenchloride; zinc
methanol
67-56-1

methanol

dihydroprogesterone
566-65-4

dihydroprogesterone

3,3-dimethoxy-5α-pregnan-20-one
18003-79-7

3,3-dimethoxy-5α-pregnan-20-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 20 - 60℃; for 1h;90%
With hydrogen; Wilkinson's catalyst
With toluene-4-sulfonic acid Heating;
With toluene-4-sulfonic acid In methanol at 25 - 65℃; for 1h;
dihydroprogesterone
566-65-4

dihydroprogesterone

(5S,6R,8R,9S,10R,13S,14S,17R)-17-Acetyl-2,2,6,17-tetrachloro-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one
185041-91-2

(5S,6R,8R,9S,10R,13S,14S,17R)-17-Acetyl-2,2,6,17-tetrachloro-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With manganese(IV) oxide; acetic acid; acetyl chloride Ambient temperature;90%
dihydroprogesterone
566-65-4

dihydroprogesterone

methylmagnesium bromide
75-16-1

methylmagnesium bromide

ganaxolone
38398-32-2

ganaxolone

Conditions
ConditionsYield
Stage #1: methylmagnesium bromide With iron(III) chloride; lithium chloride In tetrahydrofuran; diethyl ether at -35 - -30℃; for 0.5h;
Stage #2: dihydroprogesterone In tetrahydrofuran; diethyl ether at -20 - -15℃; for 2h;
81%
In toluene at -70℃; for 2h;0.3 g
dihydroprogesterone
566-65-4

dihydroprogesterone

(5S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one
65556-93-6

(5S,8S,9S,10R,13S,14S,17S)-17-acetyl-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With oxygen; palladium diacetate; trifluoroacetic acid In dimethyl sulfoxide at 80℃; for 8h; Sealed tube;81%
dihydroprogesterone
566-65-4

dihydroprogesterone

ethylmagnesium bromide
925-90-6

ethylmagnesium bromide

C23H38O2

C23H38O2

Conditions
ConditionsYield
Stage #1: dihydroprogesterone With 2,4,6-tri-tert-butylphenoxol; trimethylaluminum In toluene at -70 - 0℃; for 1h; Inert atmosphere;
Stage #2: ethylmagnesium bromide In diethyl ether; toluene at -70℃; for 1h;
78%
dihydroprogesterone
566-65-4

dihydroprogesterone

(2-nitrophenyl)hydrazine
3034-19-3

(2-nitrophenyl)hydrazine

bis-(o.nitro)fenilidrazone del 5α-pregnan-3,20-dione

bis-(o.nitro)fenilidrazone del 5α-pregnan-3,20-dione

Conditions
ConditionsYield
In ethanol for 0.5h; Heating;73%
dihydroprogesterone
566-65-4

dihydroprogesterone

acetylenemagnesium bromide
4301-14-8

acetylenemagnesium bromide

A

UC2003
178885-91-1

UC2003

B

UC2002
162883-06-9

UC2002

Conditions
ConditionsYield
In tetrahydrofuran at 20℃;A 13%
B 72%
dihydroprogesterone
566-65-4

dihydroprogesterone

N-Methyl-N,O-bis(trimethylsilyl)hydroxylamine
22737-33-3

N-Methyl-N,O-bis(trimethylsilyl)hydroxylamine

C22H35NO2
132734-44-2

C22H35NO2

Conditions
ConditionsYield
In benzene Heating;71%
dihydroprogesterone
566-65-4

dihydroprogesterone

A

isopregnanolone
516-55-2

isopregnanolone

B

tetrahydroprogesterone
516-54-1

tetrahydroprogesterone

Conditions
ConditionsYield
With trimethylamine-borane; silica gel; iron(III) chloride In benzene for 2h; Product distribution; Ambient temperature; various catalysts and times;A 66.4%
B 32.5%
With trimethylamine-borane; silica gel; iron(III) chloride In benzene for 2h; Ambient temperature;A 66.4%
B 32.5%
With ethanol; nickel Hydrogenation;
With morpholine-borane In toluene at 23℃; for 1.5h; Title compound not separated from byproducts;
dihydroprogesterone
566-65-4

dihydroprogesterone

4-methoxy-aniline
104-94-9

4-methoxy-aniline

(5S,8S,9S,10S,13S,14S,17S)-17-acetyl-2-(4-methoxyphenylamino)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

(5S,8S,9S,10S,13S,14S,17S)-17-acetyl-2-(4-methoxyphenylamino)-10,13-dimethyl-4,5,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With 2,2,6,6-tetramethyl-piperidine; trifluorormethanesulfonic acid; oxygen In m-xylene at 130℃; under 760.051 Torr; for 4h; regioselective reaction;66%
dihydroprogesterone
566-65-4

dihydroprogesterone

tetrahydroprogesterone
516-54-1

tetrahydroprogesterone

Conditions
ConditionsYield
Stage #1: dihydroprogesterone With potassium tri-sec-butyl-borohydride In tetrahydrofuran at -78℃; for 5h;
Stage #2: With sodium hydroxide; dihydrogen peroxide at 20℃; for 2h;
63%
With potassium phosphate buffer; 1,4-dihydronicotinamide adenine dinucleotide; NAD:3-α-hydroxy-5α-pregnan-20-one oxidoreductase at 37℃;
With hydrogen bromide; acetic acid; platinum Hydrogenation.unter Erwaermen und Behandlung des Reaktionsprodukts mit methanol. KOH bei Siedetemperatur;
dihydroprogesterone
566-65-4

dihydroprogesterone

A

tetrahydroprogesterone
516-54-1

tetrahydroprogesterone

B

1-((3R,5S,8R,9S,10S,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-ethanone

1-((3R,5S,8R,9S,10S,13S,14S,17R)-3-Hydroxy-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-ethanone

Conditions
ConditionsYield
With phosphonic Acid; hydrogen hexachloroiridate In water; isopropyl alcoholA 60%
B 12%
dihydroprogesterone
566-65-4

dihydroprogesterone

2α-bromo-5α-pregnane-3,20-dione
6656-43-5

2α-bromo-5α-pregnane-3,20-dione

Conditions
ConditionsYield
With hydrogen bromide; bromine In acetic acid for 0.25h;57%
With hydrogen bromide; bromine; acetic acid at 20℃;
1-methyl-2(1H)-quinoxalinone
6479-18-1

1-methyl-2(1H)-quinoxalinone

dihydroprogesterone
566-65-4

dihydroprogesterone

3-((E)-2-((5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-(hydroxyimino)-2-oxoethyl)-1-methylquinoxalin-2(1H)-one

3-((E)-2-((5S,8R,9S,10S,13S,14S,17S)-10,13-dimethyl-3-oxohexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)-1-(hydroxyimino)-2-oxoethyl)-1-methylquinoxalin-2(1H)-one

Conditions
ConditionsYield
With tert.-butylnitrite; methanesulfonic acid at 20℃; for 6h;40%
With tert.-butylnitrite; trifluoroacetic acid In dichloromethane at 20℃; for 6h;32%
dihydroprogesterone
566-65-4

dihydroprogesterone

C21H33(2)HO2

C21H33(2)HO2

Conditions
ConditionsYield
With sodium borodeuteride; sodium hydroxide In pyridine; methanol; water at 0 - 10℃; for 0.5h; Cooling with ice;35%

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