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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Sulfamethazine Manufacturer/High quality/Best price/In stock

Cas:57-68-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Sinoway Industrial Co., Ltd.

1. High quality: CP.EP 2. Big capacity: 50mt per month 3. A lower price with high quality 4. Certificate: GMP, COA 5. Package: Packed with multi-layer paper bags, with polyethylene inner bag, net weight 25kg per bag. 6. Storage should be stored

sulfadimidine sodium

Cas:57-68-1

Min.Order:25 Kilogram

FOB Price: $13.0

Type:Trading Company

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Sulfamethazine supplier in China

Cas:57-68-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Sulfamethazine Cas 57-68-1 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or whitish powder or crystals Storage:Store in 2-8℃ Package:25kg/drum

Factory best price Sulfamethazine Cas 57-68-1 with top quality

Cas:57-68-1

Min.Order:100 Kilogram

FOB Price: $14.0 / 17.0

Type:Trading Company

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Hangzhou Dingyan Chem Co., Ltd

BP2009, EP6,USP31 Package:100g,1kg,5kg,25kg Application:API Port:Shanghai or Hangzhou port

Sulfamethazine Base

Cas:57-68-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

China product 99% Sulfamethazine Powder cas:57-68-1

Cas:57-68-1

Min.Order:1 Kilogram

FOB Price: $19.0 / 29.0

Type:Manufacturers

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Hefei TNJ chemical industry co.,ltd

Properties White or yellowish crystalline powder, odorless, with slightly bitterness; color becomes dark on meeting light. It is almost insoluble in water, easy soluble in dilute acid and dilute alkali. Widely used in pharmaceutical area. Spec

Lower Price Sulfamethazine

Cas:57-68-1

Min.Order:1 Metric Ton

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Sulfadimidine

Cas:57-68-1

Min.Order:1

Negotiable

Type:Other

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Sulfamethazine manufacturer with low price

Cas:57-68-1

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Factory Price API 99% Sulfamethazine 57-68-1 GMP Manufacturer

Cas:57-68-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Sulfadimidine

Cas:57-68-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Sulfamethazine (base and/or unspecified salts)

Cas:57-68-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU-CHEM Sulfamethazine,57-68-1

Cas:57-68-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent

Sulfamethazine CAS 57-68-1 for Antiphlogosis

Cas:57-68-1

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 57-68-1 with fast shipping

Cas:57-68-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

57-68-1 Sulfadimidine/Sulfamethazine Base

Cas:57-68-1

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Sulfamethazine/ LIDE PHARMA- Factory supply / Best price

Cas:57-68-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Name: Sulfadimidine Alias: Sulfamethazine, SM2 Chemical name: N-(4,6-dimethyl-2-pyrimidinyl) -4-aminobenzenesulfonamide Structural formula : Molecular formula and molecular weight: C12H14N4O2S = 278.33 Appearance: white powder Storage:Store

Sulfadimidine CAS: 57-68-1

Cas:57-68-1

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Advantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is

Sulfamethazine CAS NO 57-68-1

Cas:57-68-1

Min.Order:1 Kilogram

Negotiable

Type:Other

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HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Sulfamethazine Powder CAS 57-68-1 GMP Factory Supply Veterinary Medicine

Cas:57-68-1

Min.Order:1 Kilogram

FOB Price: $200.0 / 400.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzenesulfonamide,4-amino-N-(4,6-dimethyl-2-pyrimidinyl)- 57-68-1

Cas:57-68-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Leader Biochemical Group

About Product Details Items Specifications Test Results Appearance White to white crystalline powde

China Biggest Factory Manufacturer Supply Sulfamethazine CAS 57-68-1

Cas:57-68-1

Min.Order:100 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Hunan chemfish Pharmaceutical co.,Ltd

GMP/DMF Appearance:conforms Storage:2-8°C Package:as client requirement Application:57-68-1 Transportation:Express, Air ,Sea Port:Any port of China

Sulfamethazine Base/Sulfadimidine/Sulphadimidine

Cas:57-68-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Antibacterial drugs/Sulfamethazine with CAS:57-68-1

Cas:57-68-1

Min.Order:1 Kilogram

FOB Price: $24.0 / 30.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Sulfamethazine CAS:57-68-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Sulfamethazine CAS:57-68-1

Cas:57-68-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzenesulfonamide,4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-

Cas:57-68-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi

Antiparasitic agents Sulfamethazine powder with 99% purity

Cas:57-68-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

Sulfamethazine cas:57-68-1

Cas:57-68-1

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. 3) OEM/ODM Available; 4) Reasonable & Compet

Lower price Sulfamethazine CAS 57-68-1 with best quality

Cas:57-68-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Synthetic route

2-chloro-4,6-dimethylpyrimidine
4472-44-0

2-chloro-4,6-dimethylpyrimidine

sulfanilamide
63-74-1

sulfanilamide

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
With potassium carbonate
(E)-4-(piperidino)pent-3-en-2-one
63913-41-7

(E)-4-(piperidino)pent-3-en-2-one

1-amino-4-({[amino(imino)methyl]amino}sulfonyl)benzene
57-67-0

1-amino-4-({[amino(imino)methyl]amino}sulfonyl)benzene

sulfadimesine
57-68-1

sulfadimesine

N-(4,6-dimethyl-pyrimidin-2-yl)-4-nitro-benzenesulfonamide
153312-38-0

N-(4,6-dimethyl-pyrimidin-2-yl)-4-nitro-benzenesulfonamide

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
With hydrogenchloride; iron
With hydrogenchloride; iron
N-[4-(4,6-Dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-acetamide
100-90-3

N-[4-(4,6-Dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-acetamide

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
With sodium hydroxide
With calcium hydroxide
[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-carbamic acid ethyl ester
50910-49-1

[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-carbamic acid ethyl ester

sulfadimesine
57-68-1

sulfadimesine

acetylacetone
123-54-6

acetylacetone

1-amino-4-({[amino(imino)methyl]amino}sulfonyl)benzene
57-67-0

1-amino-4-({[amino(imino)methyl]amino}sulfonyl)benzene

sulfadimesine
57-68-1

sulfadimesine

sulfanilamide
63-74-1

sulfanilamide

4,6-dimethyl-2-phenoxy-pyrimidine
7220-71-5

4,6-dimethyl-2-phenoxy-pyrimidine

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
With potassium carbonate
acetamide
60-35-5

acetamide

sodium-compound of sulfanilamide

sodium-compound of sulfanilamide

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
anschliessendes Erhitzen mit <4,6-Dimethyl-pyrimidin-2-yl>-trimethyl-ammonium-chlorid;
2-chloro-4,6-dimethylpyrimidine
4472-44-0

2-chloro-4,6-dimethylpyrimidine

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Na2CO3
2: aq. NaOH solution
View Scheme
Multi-step reaction with 2 steps
1: K2CO3; toluene
2: K2CO3
View Scheme
2-Amino-4,6-dimethylpyrimidine
767-15-7

2-Amino-4,6-dimethylpyrimidine

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: iron-powder; aq.-ethanolic HCl
View Scheme
Multi-step reaction with 2 steps
2: aq. NaOH solution
View Scheme
acetylacetone
123-54-6

acetylacetone

sulfadimesine
57-68-1

sulfadimesine

4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: iron-powder; aq.-ethanolic HCl
View Scheme
p-acetylaminobenzenesulfonamide
121-61-9

p-acetylaminobenzenesulfonamide

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Na2CO3
2: aq. NaOH solution
View Scheme
p-acetylaminobenzenesulfonyl chloride
121-60-8

p-acetylaminobenzenesulfonyl chloride

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: aq. NaOH solution
View Scheme
2-Amino-4,6-dimethylpyrimidine
767-15-7

2-Amino-4,6-dimethylpyrimidine

4-Nitrobenzenesulfonyl chloride
98-74-8

4-Nitrobenzenesulfonyl chloride

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
2: hydrogenchloride; iron
View Scheme
4-aminobenzenesulfonyl chloride
24939-24-0

4-aminobenzenesulfonyl chloride

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium hydrogencarbonate
2: acetic acid
View Scheme
sulfadimesine
57-68-1

sulfadimesine

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

N-(4,6-dimethyl-pyrimidin-2-yl)-4-tetrazol-1-yl-benzenesulfonamide

N-(4,6-dimethyl-pyrimidin-2-yl)-4-tetrazol-1-yl-benzenesulfonamide

Conditions
ConditionsYield
With sodium azide; acetic acid at 80 - 95℃;98%
sulfadimesine
57-68-1

sulfadimesine

Glycyrrhizin ammonium
53956-04-0

Glycyrrhizin ammonium

C42H62O16*C12H14N4O2S*H3N

C42H62O16*C12H14N4O2S*H3N

Conditions
ConditionsYield
at 20℃;97%
sulfadimesine
57-68-1

sulfadimesine

Methacryloyl chloride
920-46-7

Methacryloyl chloride

methacryloyl sulfamethazine
59941-98-9

methacryloyl sulfamethazine

Conditions
ConditionsYield
With sodium hydroxide In water; acetone at 20℃; for 1.5h; Cooling with ice;97%
With dmap; triethylamine In dichloromethane at 0 - 20℃;
sulfadimesine
57-68-1

sulfadimesine

nicotinamide
98-92-0

nicotinamide

C12H14N4O2S*C6H6N2O

C12H14N4O2S*C6H6N2O

Conditions
ConditionsYield
With acetonitrile at 70℃; for 0.0666667h; Microwave irradiation;96.7%
sulfadimesine
57-68-1

sulfadimesine

5-chlorosalicyclaldehyde
635-93-8

5-chlorosalicyclaldehyde

4-((5-chloro-2-hydroxybenzylidene)amino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
128032-83-7

4-((5-chloro-2-hydroxybenzylidene)amino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
In ethanol for 3h; Reflux;96%
sulfadimesine
57-68-1

sulfadimesine

salicylaldehyde
90-02-8

salicylaldehyde

4-{[(1E)-(2-hydroxy-1-salicyl)methylene]-amino}-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
16182-36-8

4-{[(1E)-(2-hydroxy-1-salicyl)methylene]-amino}-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With acetic acid In ethanol for 4h; Reflux;95.4%
sulfadimesine
57-68-1

sulfadimesine

4-chloro-benzoyl chloride
122-01-0

4-chloro-benzoyl chloride

4-chloro-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)benzamide

4-chloro-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)benzamide

Conditions
ConditionsYield
In acetonitrile at 20℃; Reflux;94%
In N,N-dimethyl-formamide for 1h; Heating;79%
sulfadimesine
57-68-1

sulfadimesine

diazepam
439-14-5

diazepam

4-([4-{7-chloro-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl}phenyl]diazenyl)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

4-([4-{7-chloro-1-methyl-2-oxo-2,3-dihydro-1H-benzo[e][1,4]diazepin-5-yl}phenyl]diazenyl)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
Stage #1: sulfadimesine With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.0833333h; Green chemistry;
Stage #2: diazepam With sodium acetate In ethanol; water Green chemistry;
94%
BARBITURIC ACID
67-52-7

BARBITURIC ACID

sulfadimesine
57-68-1

sulfadimesine

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

N-(4,6-dimethylpyrimidin-2-yl)-4-{[(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)methyl]amino}benzenesulfonamide
392663-27-3

N-(4,6-dimethylpyrimidin-2-yl)-4-{[(2,4,6-trioxotetrahydropyrimidin-5(2H)-ylidene)methyl]amino}benzenesulfonamide

Conditions
ConditionsYield
In iso-butanol for 3h; Reflux;93%
sulfadimesine
57-68-1

sulfadimesine

N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
6149-31-1

N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With boron trifluoride diethyl etherate; sodium nitrite In N,N-dimethyl-formamide at 20℃; for 1h;93%
sulfadimesine
57-68-1

sulfadimesine

trimethylsulfoxonium iodide
1774-47-6

trimethylsulfoxonium iodide

4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-N-methylbenzenesulfonamide
63826-13-1

4-amino-N-(4,6-dimethyl-2-pyrimidinyl)-N-methylbenzenesulfonamide

Conditions
ConditionsYield
With aluminum oxide; potassium hydroxide at 130℃; for 0.0666667h; microwave irradiation;92%
sulfadimesine
57-68-1

sulfadimesine

C12H8N6OS2

C12H8N6OS2

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

4-{[({8-cyano-4-oxo-3-[2-(2-thienyl)vinyl]-4H,8H-[1,2,4]triazino[3,4b][1,3,4]thiadiazin-7-yl}amino)(ethoxy)methyl]amino}-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

4-{[({8-cyano-4-oxo-3-[2-(2-thienyl)vinyl]-4H,8H-[1,2,4]triazino[3,4b][1,3,4]thiadiazin-7-yl}amino)(ethoxy)methyl]amino}-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With acetic anhydride; acetic acid for 3h; Reflux;92%
sulfadimesine
57-68-1

sulfadimesine

(E)-3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)-2-propen-1-one
127172-22-9

(E)-3-(N,N-dimethylamino)-1-(3,4-dimethoxyphenyl)-2-propen-1-one

Z-4-(3-(3,4-dimethoxyphenyl)-3-oxoprop-1-enylamino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Z-4-(3-(3,4-dimethoxyphenyl)-3-oxoprop-1-enylamino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With acetic acid In ethanol for 22h; Reflux;92%
sulfadimesine
57-68-1

sulfadimesine

2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

C19H16N6O2S3

C19H16N6O2S3

Conditions
ConditionsYield
Stage #1: sulfadimesine With hydrogenchloride; sodium nitrite In ethanol at 0 - 5℃;
Stage #2: 2-Mercaptobenzothiazole With sodium hydroxide In ethanol at 5 - 20℃; for 6h;
91%
Conditions
ConditionsYield
With acetic acid In ethanol at 60℃; for 3h;91%
4-chlorobenzoquinazoline
33987-02-9

4-chlorobenzoquinazoline

sulfadimesine
57-68-1

sulfadimesine

4-(benzo[g]quinazolin-4-ylamino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

4-(benzo[g]quinazolin-4-ylamino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 24h; Reflux;91%
sulfadimesine
57-68-1

sulfadimesine

(Z)-3-(dimethylamino)-1-(10H-phenothiazin-2-yl)prop-2-en-1-one

(Z)-3-(dimethylamino)-1-(10H-phenothiazin-2-yl)prop-2-en-1-one

(Z)-N-(4,6-dimethylpyrimidin-2-yl)-4-(3-oxo-3-(10H-phenothiazine-2yl)prop-1-enylamino)benzenesulfonamide

(Z)-N-(4,6-dimethylpyrimidin-2-yl)-4-(3-oxo-3-(10H-phenothiazine-2yl)prop-1-enylamino)benzenesulfonamide

Conditions
ConditionsYield
In ethanol for 18h; Reflux;91%
succinic acid anhydride
108-30-5

succinic acid anhydride

sulfadimesine
57-68-1

sulfadimesine

N-[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-succinamic acid
85828-79-1

N-[4-(4,6-dimethyl-pyrimidin-2-ylsulfamoyl)-phenyl]-succinamic acid

Conditions
ConditionsYield
In acetone Acylation;90%
sulfadimesine
57-68-1

sulfadimesine

cobalt(II) chloride
7646-79-9

cobalt(II) chloride

Co(H2O)2(C12H13N4O2S)2
188414-31-5

Co(H2O)2(C12H13N4O2S)2

Conditions
ConditionsYield
With NaOH In water dissoln. of sulphadimidine in aq. NaOH, addn. into soln. of metal salt (stoichiom. ratio; pptn. immediately); recrystn. (N,N-dimethylformamide), filtration after 2 weeks, washing (water, EtOH), air drying; elem. anal.;90%
sulfadimesine
57-68-1

sulfadimesine

nickel dichloride

nickel dichloride

Ni(H2O)2(C12H13N4O2S)2
84812-74-8

Ni(H2O)2(C12H13N4O2S)2

Conditions
ConditionsYield
With NaOH In water dissoln. of sulphadimidine in aq. NaOH, addn. into soln. of metal salt (stoichiom. ratio; pptn. immediately); recrystn. (N,N-dimethylformamide), filtration after 2 weeks, washing (water, EtOH), air drying; elem. anal.;90%
2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine
444731-75-3

2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine

sulfadimesine
57-68-1

sulfadimesine

4-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide
1572439-28-1

4-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With hydrogenchloride In water; isopropyl alcohol at 85℃;90%
4-chloro-2-phenylquinazoline
6484-25-9

4-chloro-2-phenylquinazoline

sulfadimesine
57-68-1

sulfadimesine

N-(4,6-dimethylpyrimidin-2-yl)-4-(2-phenylquinazolin-4-ylamino)benzenesulfonamide

N-(4,6-dimethylpyrimidin-2-yl)-4-(2-phenylquinazolin-4-ylamino)benzenesulfonamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 22h; Reflux;90%
2-chloro-6-methylnicotinonitrile
28900-10-9

2-chloro-6-methylnicotinonitrile

sulfadimesine
57-68-1

sulfadimesine

4-(3-cyano-6-methylpyridin-2-ylamino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

4-(3-cyano-6-methylpyridin-2-ylamino)-N-(4,6-dimethylpyrimidin-2-yl)benzenesulfonamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide for 18h; Reflux;90%
sulfadimesine
57-68-1

sulfadimesine

2-cyano-N-(5-ethyl-[1,3,4]-thiadiazol-2-yl)acetamide
544431-10-9

2-cyano-N-(5-ethyl-[1,3,4]-thiadiazol-2-yl)acetamide

(E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-2-((5-ethyl-1,3,4-thiadiazol-2-yl)amino)-2-oxoacetohydrazonoyl cyanide

(E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-2-((5-ethyl-1,3,4-thiadiazol-2-yl)amino)-2-oxoacetohydrazonoyl cyanide

Conditions
ConditionsYield
Stage #1: sulfadimesine With hydrogenchloride; sodium nitrite In water Cooling;
Stage #2: 2-cyano-N-(5-ethyl-[1,3,4]-thiadiazol-2-yl)acetamide With pyridine In water at 0 - 5℃;
90%
formaldehyd
50-00-0

formaldehyd

3-amino-2-phenylquinazolin-4(3H)-one
1904-60-5

3-amino-2-phenylquinazolin-4(3H)-one

sulfadimesine
57-68-1

sulfadimesine

Conditions
ConditionsYield
With hydrogenchloride In methanol for 6h; Mannich reaction; Reflux;89.5%
4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine
5334-48-5

4-chloro-1-(phenyl)-1H-pyrazolo[3,4-d]pyrimidine

sulfadimesine
57-68-1

sulfadimesine

N-(4,6-dimethyl-pyrimidin-2-yl)-4-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-benzenesulfonamide

N-(4,6-dimethyl-pyrimidin-2-yl)-4-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)-benzenesulfonamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide for 12h; Heating;89%
4,6-dihydroxy-2-mercaptopyrimidine
504-17-6

4,6-dihydroxy-2-mercaptopyrimidine

sulfadimesine
57-68-1

sulfadimesine

orthoformic acid triethyl ester
122-51-0

orthoformic acid triethyl ester

N-(4,6-dimethylpyrimidin-2-yl)-4-{[(4,6-dioxo-2-thioxotetrahydropyrimidin-5(2H)-ylidene)methyl]amino}benzenesulfonamide
1021228-88-5

N-(4,6-dimethylpyrimidin-2-yl)-4-{[(4,6-dioxo-2-thioxotetrahydropyrimidin-5(2H)-ylidene)methyl]amino}benzenesulfonamide

Conditions
ConditionsYield
In iso-butanol for 3h; Reflux;89%
sulfadimesine
57-68-1

sulfadimesine

3-fluoro-4-(trifluoromethyl)benzoyl chloride

3-fluoro-4-(trifluoromethyl)benzoyl chloride

N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-fluoro-4-(trifluoromethyl)benzamide

N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-fluoro-4-(trifluoromethyl)benzamide

Conditions
ConditionsYield
In acetonitrile at 20℃; Reflux;89%
sulfadimesine
57-68-1

sulfadimesine

((E)-3-(3-(dimethylamino)acryloyl))-2H-chromen-2-one
371756-61-5

((E)-3-(3-(dimethylamino)acryloyl))-2H-chromen-2-one

(Z)-N-(4,6-dimethylpyrimidin-2-yl)-4-(3-oxo-3-(2-oxo-2H-chromen-3-yl)prop-1-enylamino)benzenesulfonamide

(Z)-N-(4,6-dimethylpyrimidin-2-yl)-4-(3-oxo-3-(2-oxo-2H-chromen-3-yl)prop-1-enylamino)benzenesulfonamide

Conditions
ConditionsYield
In ethanol for 21h; Reflux;88%
2-imino-4,5,5-trimethyl-2,5-dihydrofuran-3-carboxamide
1108179-85-6

2-imino-4,5,5-trimethyl-2,5-dihydrofuran-3-carboxamide

sulfadimesine
57-68-1

sulfadimesine

2-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenylimino)-4,5,5-trimethyl-2,5-dihydrofuran-3-carboxamide

2-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenylimino)-4,5,5-trimethyl-2,5-dihydrofuran-3-carboxamide

Conditions
ConditionsYield
With acetic acid at 65 - 70℃;88%

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