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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Chloro-2-fluoroaniline Manufacturer/High quality/Best price/In stock

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Fluoro-4-Chloroaniline supplier in China

Cas:57946-56-2

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Jinan Finer Chemical Co., Ltd

Product Description Product website: http://www.finerchem.com Product Name 4-CHLORO-2-FLUOROANILINE CAS No. 57946-56-2 Appearance

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Gram

FOB Price: $8.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-Chloro-2-Fluoroaniline

Cas:57946-56-2

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 4-Chloro-2-fluoroaniline Synonyms: 4-CHLORO-2-FLUOROANILINE;4-CHLORO-2-FLUOROBENZENAMINE;4-CHLORO-2-FLUORO-PHENYLAMINE;2-FLUORO-4-CHLOROANILINE;TIMTEC-BB SBB004111;4-Chloro-2-fluoroaniline,98%;4-Chloro-2-fluoroaniline 98%

57946-56-2 4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Gram

FOB Price: $8900.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 57946-56-2 with competitive price

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product name 4-Chloro-2-fluoroaniline Synonyms 4-CHLORO-2-FLUOROANILINE;4-CHLORO-2-FLUOROBENZENAMINE;4-Chloro-2-fluoroaniline,98%;4-CHLORO-2-FLUORO-PHENYLAMINE;2-FLUORO-4-CHLOROANILINE;TIMTEC-BB SBB0

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzenamine, 4-chloro-2-fluoro- 57946-56-2

Cas:57946-56-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu

4-Chloro-2-Fluoroaniline : 57946-56-2

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $65.0 / 80.0

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzenamine, 4-chloro-2-fluoro-

Cas:57946-56-2

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzenamine, 4-chloro-2-fluoro-

Cas:57946-56-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Fluoro-4-Chloroaniline

Cas:57946-56-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Name: 4-Chloro-2-fluoroaniline CAS NO.: 57946-56-2 Structural formula: Appearance: colorless to light yellow liquid, boiling point: 104~107°C/28Torr

4-Chloro-2-fluoroaniline manufacture

Cas:57946-56-2

Min.Order:50 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-CHLORO-2-FLUOROANILINE

Cas:57946-56-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

4-Chloro-2-fluoroanilineAppearance:white powder Storage:In Shade Package:according to customers' requirements Application:pharmaceutical intermediate Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or accor

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

4-Chloro-2-fluoroaniline Chemical Properties Boiling point 104-107 °C (28 mmHg) density 1.311 g/mL at 25 °C (lit.) refractive index n20/D 1.56(lit.) Fp 210 °F storage temp. Room temperature. pka 2.57±0.10(Pre

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

57946-56-2 CAS NO.57946-56-2

Cas:57946-56-2

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Chloro-2-fluorobenzenamine

Cas:57946-56-2

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

4-Chloro-2-fluoroaniline

Cas:57946-56-2

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Changzhou Anchor Biological Technology Co., Ltd.

Our company is engaged in customizing the benzene ring and pyridine derivative organic intermediates, and the quantity is flexible according to customer's needs. It mainly provides high-quality intermediates for domestic and foreign pharmaceutical an

4-Chloro-2-fluoroaniline Manufacturer/High quality/Best price/In stock CAS NO.57946-56-2

Cas:57946-56-2

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

4'-chloro-2'-fluoroacetanilide
59280-70-5

4'-chloro-2'-fluoroacetanilide

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With sodium hydroxide; water In ethanol for 3h; Reflux;95.6%
With sodium hydroxide In ethanol; water
With sodium hydroxide In ethanol; water
2-Fluoroaniline
348-54-9

2-Fluoroaniline

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With copper dichloride; 1-hexyl-3-methylimidazol-1-ium chloride at 40℃; for 4h; regioselective reaction;88%
With iron(III) chloride; N-chloro-succinimide; 1-butyl-3-methylimidazolium trifluoromethanesulfonimide In tetrahydrofuran at 60℃; for 18h; Inert atmosphere; regioselective reaction;75%
4-chloro-2-fluorobenzoic acid
446-30-0

4-chloro-2-fluorobenzoic acid

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With sodium azide; sulfuric acid
4-chloro-aniline
106-47-8

4-chloro-aniline

A

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

B

4-chloro-3-fluoroaniline
367-22-6

4-chloro-3-fluoroaniline

C

4-chloro-3,5-difluorobenzenamine
2613-33-4

4-chloro-3,5-difluorobenzenamine

D

4-chloro-2,5-difluoroaniline
2613-30-1

4-chloro-2,5-difluoroaniline

Conditions
ConditionsYield
With trifluorormethanesulfonic acid; fluorine at 20℃; Further byproducts given. Title compound not separated from byproducts;
CH3 NO2

CH3 NO2

4-chloro-2-fluorobenzoic acid
446-30-0

4-chloro-2-fluorobenzoic acid

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With sodium hydroxide; PPA
N-(2-fluorophenyl)acetamide
399-31-5

N-(2-fluorophenyl)acetamide

A

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

B

4'-chloro-2'-fluoroacetanilide
59280-70-5

4'-chloro-2'-fluoroacetanilide

Conditions
ConditionsYield
With chlorine In acetic acid
With chlorine In acetic acid
With chlorine In acetic acid
4-chloro-2-fluoro-nitrobenzene
700-37-8

4-chloro-2-fluoro-nitrobenzene

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With 2 wt% Pd/C; hydrogen at 120℃; under 7500.75 Torr;
C15H14ClFN2

C15H14ClFN2

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With sodium tetrahydroborate; copper(l) chloride In ethanol at 20℃;23.6 mg
bis-(4-chloro-phenyl)-diazene
1602-00-2

bis-(4-chloro-phenyl)-diazene

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 90 °C / Sealed tube
2: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C
View Scheme
C15H15ClN2

C15H15ClN2

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bis(dibenzylideneacetone)-palladium(0); N-fluorobis(benzenesulfon)imide; potassium nitrate / ethyl acetate / 12 h / 100 °C / Sealed tube
2: sodium tetrahydroborate; copper(l) chloride / ethanol / 20 °C
View Scheme
C12H7Cl2FN2

C12H7Cl2FN2

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Conditions
ConditionsYield
With sodium tetrahydroborate; copper(l) chloride In ethanol at 20℃;28.4 mg
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

ethyl 4-chloro-6,7-dimethoxyquinoline-3-carboxylate
26893-14-1

ethyl 4-chloro-6,7-dimethoxyquinoline-3-carboxylate

ethyl 4-((4-chloro-2-fluorophenyl)amino)-6,7-dimethoxyquinoline-3-carboxylate

ethyl 4-((4-chloro-2-fluorophenyl)amino)-6,7-dimethoxyquinoline-3-carboxylate

Conditions
ConditionsYield
In isopropyl alcohol at 20 - 100℃; for 16h; Inert atmosphere;99%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-chloro-1H-pyrrolo[2,3-d]pyrimidine
3680-69-1

4-chloro-1H-pyrrolo[2,3-d]pyrimidine

(4-chloro-2-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine
865364-20-1

(4-chloro-2-fluoro-phenyl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Conditions
ConditionsYield
With silver trifluoromethanesulfonate In N,N-dimethyl-formamide at 90℃;98%
2-thienylacetic acid chloride
39098-97-0

2-thienylacetic acid chloride

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

C12H9ClFNOS

C12H9ClFNOS

Conditions
ConditionsYield
In tetrahydrofuran at 20℃;98%
4-Chloro-6-cyano-7-(2-methoxyethoxy)quinoline hydrochloride
205448-26-6

4-Chloro-6-cyano-7-(2-methoxyethoxy)quinoline hydrochloride

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-(4-chloro-2-fluoroanilino)-6-cyano-7-(2-methoxyethoxy)quinoline hydrochloride
205447-78-5

4-(4-chloro-2-fluoroanilino)-6-cyano-7-(2-methoxyethoxy)quinoline hydrochloride

Conditions
ConditionsYield
In isopropyl alcohol for 3h; Heating / reflux;98%
tert-butyl 4-{[(4-chloro-6-methoxyquinazolin-7-yl)oxy]methyl}piperidine-1-carboxylate
401811-89-0

tert-butyl 4-{[(4-chloro-6-methoxyquinazolin-7-yl)oxy]methyl}piperidine-1-carboxylate

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-(4-chloro-2-fluoroanilino)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazoline
338992-08-8

4-(4-chloro-2-fluoroanilino)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazoline

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane; isopropyl alcohol for 4h; Heating / reflux;98%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-chloro-2-fluoro-6-iodophenylamine
216393-67-8

4-chloro-2-fluoro-6-iodophenylamine

Conditions
ConditionsYield
With silver(II) sulfate; iodine In ethanol at 20℃; for 2h;98%
With trifluorormethanesulfonic acid; bis(pyridine)iodonium(I) tetrafluoroborate In dichloromethane91%
With iodine; silver sulfate In ethanol at 20℃; for 1.5h;87%
isopropanolic hydrogen chloride

isopropanolic hydrogen chloride

4-chloro-6-methoxy-7-(3-morpholinopropoxy)cinnoline hydrochloride

4-chloro-6-methoxy-7-(3-morpholinopropoxy)cinnoline hydrochloride

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-(4-chloro-2-fluoroanilino)-6-methoxy-7-(3-morpholinopropoxy)cinnoline hydrochloride

4-(4-chloro-2-fluoroanilino)-6-methoxy-7-(3-morpholinopropoxy)cinnoline hydrochloride

Conditions
ConditionsYield
In (+/-)-2-pentanol; isopropyl alcohol98%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

(4-chloro-2-fluorophenyl)hydrazine hydrochloride

(4-chloro-2-fluorophenyl)hydrazine hydrochloride

Conditions
ConditionsYield
Stage #1: 2-fluoro-4-chloroaniline With barium nitrite In water at 45℃; Acidic conditions; Flow reactor;
Stage #2: With potassium bisulfite In water at 60 - 89℃;
Stage #3: With hydrogenchloride In water at 85℃;
97.2%
Stage #1: 2-fluoro-4-chloroaniline With hydrogenchloride In water at 0℃;
Stage #2: With sodium nitrite In water at 0 - 20℃;
Stage #3: With hydrogenchloride; tin(II) chloride dihdyrate In water at 0 - 20℃; for 4.5h;
62%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

acetic anhydride
108-24-7

acetic anhydride

4'-chloro-2'-fluoroacetanilide
59280-70-5

4'-chloro-2'-fluoroacetanilide

Conditions
ConditionsYield
In acetic acid at 20℃; for 2h;95%
With acetic acid at 20℃; for 2h;95%
With pyridine at 120℃; for 2h;
In acetic acid at 20℃; for 3h;
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

chloroformic acid ethyl ester
541-41-3

chloroformic acid ethyl ester

ethyl N-(4-chloro-2-fluorophenyl)carbamate
114108-90-6

ethyl N-(4-chloro-2-fluorophenyl)carbamate

Conditions
ConditionsYield
With pyridine at 0℃; for 3h;95%
With hydrogenchloride In pyridine
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

benzoyl chloride
98-88-4

benzoyl chloride

N-(4-chloro-2-fluorophenyl)benzamide

N-(4-chloro-2-fluorophenyl)benzamide

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran for 16h;95%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

2,6-difluorobenzaldehyde
437-81-0

2,6-difluorobenzaldehyde

(E)-N-(4-chloro-2-fluorophenyl)-1-(2,6-difluorophenyl)methanimine

(E)-N-(4-chloro-2-fluorophenyl)-1-(2,6-difluorophenyl)methanimine

Conditions
ConditionsYield
In toluene at 110℃; for 96h; Dean-Stark;95%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

7-benzyloxy-4-chloro-6-methoxyquinazoline
162364-72-9

7-benzyloxy-4-chloro-6-methoxyquinazoline

7-benzyloxy-4-(4-chloro-2-fluorophenylamino)-6-methoxyquinazoline hydrochloride

7-benzyloxy-4-(4-chloro-2-fluorophenylamino)-6-methoxyquinazoline hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In isopropyl alcohol for 2h; Reflux;94%
In isopropyl alcohol64%
In isopropyl alcohol for 1.5h; Heating / reflux;64%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

acetic acid
64-19-7

acetic acid

4'-chloro-2'-fluoroacetanilide
59280-70-5

4'-chloro-2'-fluoroacetanilide

Conditions
ConditionsYield
In acetic acid at 25℃; for 2h;94%
With acetic anhydride at 25℃; for 2h;
1,1,1,2,2,2-hexamethyldisilane
1450-14-2

1,1,1,2,2,2-hexamethyldisilane

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

2-fluoro-4-trimethylsilanylphenylamine
955372-99-3

2-fluoro-4-trimethylsilanylphenylamine

Conditions
ConditionsYield
With potassium fluoride; Pd(dibenzylideneacetone)2 chloroform adduct; dicyclohexylphenylphosphine In 1,4-dioxane at 100℃; for 18h;93%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

Ethyl oxalyl chloride
4755-77-5

Ethyl oxalyl chloride

N-(2-fluoro-4-chlorophenyl)oxalamic acid ethyl ester

N-(2-fluoro-4-chlorophenyl)oxalamic acid ethyl ester

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran at 20℃; for 12h;92%
With triethylamine In tetrahydrofuran at 0 - 20℃; Inert atmosphere;90%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

2,5-hexanedione
110-13-4

2,5-hexanedione

1-(4-chloro-2-fluorophenyl)-2,5-dimethyl-1H-pyrrole

1-(4-chloro-2-fluorophenyl)-2,5-dimethyl-1H-pyrrole

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 2h; Reflux;92%
With aminosulfonic acid at 20℃; for 3h;
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

trans-4-methoxy-3-buten-2-one
51731-17-0

trans-4-methoxy-3-buten-2-one

(Z)-4-((4-chloro-2-fluorophenyl)amino)-but-3-en-2-one

(Z)-4-((4-chloro-2-fluorophenyl)amino)-but-3-en-2-one

Conditions
ConditionsYield
In water at 60℃; for 0.5h;92%
ethereal hydrogen chloride

ethereal hydrogen chloride

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4,7-dichloro-6-nitro-quinazoline
162012-71-7

4,7-dichloro-6-nitro-quinazoline

7-chloro-4-(4-chloro-2-fluoroanilino)-6-nitroquinazoline hydrochloride
205194-09-8

7-chloro-4-(4-chloro-2-fluoroanilino)-6-nitroquinazoline hydrochloride

Conditions
ConditionsYield
In isopropyl alcohol90%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

methyl 2-azido-2-benzamidoacetate
194365-76-9

methyl 2-azido-2-benzamidoacetate

methyl 2-benzamido-2-(4-chloro-2-fluorophenylamino)acetate
1258422-70-6

methyl 2-benzamido-2-(4-chloro-2-fluorophenylamino)acetate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In acetone at 20℃; for 48h;90%
3,3,3-Trifluoropropionic acid
2516-99-6

3,3,3-Trifluoropropionic acid

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

N-(4-chloro-2-fluoro-phenyl)-3,3,3-trifluoro-propionamide
1538626-78-6

N-(4-chloro-2-fluoro-phenyl)-3,3,3-trifluoro-propionamide

Conditions
ConditionsYield
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane90%
With triethylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane90%
With triethylamine; HATU In dichloromethane
di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

tert-butyl (4-chloro-2-fluorophenyl)carbamate
956828-47-0

tert-butyl (4-chloro-2-fluorophenyl)carbamate

Conditions
ConditionsYield
In 1,4-dioxane for 48h; Reflux;89%
In 1,4-dioxane for 48h; Reflux;89%
In 1,4-dioxane for 48h; Reflux;89%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-methoxy-benzoyl chloride
100-07-2

4-methoxy-benzoyl chloride

N-(4-chloro-2-fluorophenyl)-4-methoxybenzamide

N-(4-chloro-2-fluorophenyl)-4-methoxybenzamide

Conditions
ConditionsYield
With triethylamine In tetrahydrofuran for 16h;88%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

2-((5-bromo-2-chloropyrimidin-4-yl)oxy)-N-methylbenzamide

2-((5-bromo-2-chloropyrimidin-4-yl)oxy)-N-methylbenzamide

2-((5-bromo-2-((4-chloro-2-fluorophenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide

2-((5-bromo-2-((4-chloro-2-fluorophenyl)amino)pyrimidin-4-yl)oxy)-N-methylbenzamide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In tetrahydrofuran at 80℃;88%
isatoic anhydride
118-48-9

isatoic anhydride

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

3-(4-chloro-2-fluorophenyl)quinazolin-4(3H)-one

3-(4-chloro-2-fluorophenyl)quinazolin-4(3H)-one

Conditions
ConditionsYield
With triethylamine sulfate; orthoformic acid triethyl ester In neat (no solvent) at 20℃; Niementowski Quinazolone Synthesis;88%
cuprous (I) chloride

cuprous (I) chloride

2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-chloro-2-fluorobenzenesulfonyl chloride
141337-26-0

4-chloro-2-fluorobenzenesulfonyl chloride

Conditions
ConditionsYield
With hydrogenchloride; acetic acid; sodium nitrite In water87.1%
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-chloro-2-fluoro-phenyl isothiocyanate
68034-69-5

4-chloro-2-fluoro-phenyl isothiocyanate

N,N'-Di(2-fluoro-4-chlorophenyl)thiourea
354151-70-5

N,N'-Di(2-fluoro-4-chlorophenyl)thiourea

Conditions
ConditionsYield
In ethanol at 20℃;87%
In ethanol at 20℃; for 8h;
2-fluoro-4-chloroaniline
57946-56-2

2-fluoro-4-chloroaniline

4-chloro-2-fluoro-5-nitroaniline
86988-02-5

4-chloro-2-fluoro-5-nitroaniline

Conditions
ConditionsYield
With nitric acid In sulfuric acid86%
With nitric acid In sulfuric acid86%
With nitric acid In sulfuric acid
With nitric acid In sulfuric acid
With sulfuric acid; nitric acid

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