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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

(R)-2-(4-Methoxyphenyl)-1-methylethanamine Manufacturer/High quality/Best price/In stock

Cas:58993-79-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 58993-79-6 with competitive price

Cas:58993-79-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

(R)-2-(4-Methoxyphenyl)-1-methylethanamine CAS:58993-79-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in hig

(R)-2-(4-Methoxyphenyl)-1-methylethanamine CAS:58993-79-6

Cas:58993-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzeneethanamine,4-methoxy-a-methyl-, (aR)-

Cas:58993-79-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzeneethanamine,4-methoxy-a-methyl-, (aR)-

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

(2r)-1-(4-methoxyphenyl)propan-2-amine

Cas:58993-79-6

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: (R)-2-(4-Methoxyphenyl)-1-methylethanamine Synonyms: R-(-)-2-(P-Methoxyphenyl)-1-methy ethamine;(R)-1-methyl-2-(4-methoxyphenyl)-ethylamine;(R)-2-(4-Methoxyphenyl)-1-methylethanamine;(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamine;(2R)

58993-79-6---(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Other

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

(R)-(-)-2-(4-Methoxyphenyl)-1-Methylethylamine

Cas:58993-79-6

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzeneethanamine,4-methoxy-a-methyl-, (aR)-

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

(2R)-1-(4-methoxyphenyl)propan-2-amine CAS No.58993-79-6

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:White to Off-White Solid Storage:Keep it in dry,shady and cool place Package:as your requirement Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by Sea

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white to yellow crystal powder Storage:Room temperature with sealed well Package:according to the clients requirement Applicatio

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

(R)-2-(4-Methoxyphenyl)-1-methylethanamine cas 58993-79-6Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

(R)-2-(4-Methoxyphenyl)-1-methylethanamine cas 58993-79-6

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan Longxianng Runhui Trading Co.,Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

58993-79-6

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

HENAN SUNLAKE ENTERPRISE CORPORATION

Henan Sunlake Enterprise Corporation is located in Henan Province, the central plain of China , Which enjoys favorable geogeaphical position and convenient transportion. The comany was established in june 1998 , until now having more than 18 years

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zhengzhou Kingorgchem Chemical Technology Co., Ltd.

Zhengzhou Kingorgchem Chemical Technology Co., Ltd. was founded on the basis of Organophosphorus Chemistry Lab of Institute of Chemistry Henan Academy of Sciences in 2015. The laboratory covers 600 m2 and the pilot plant covers 2000 m2. Kingorgchem i

National Research Platform ISO 9001 58993-79-6

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

suzhou BetterBioChem Co., Ltd.

Betterbiochem is specialized in APIs, pharmaceutical intermediates & fine chemicals. 1. The best quality, competitive price. 2. The best service before or after shipment. 3. Rich experience in export operation. 4. Rich experience in

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai AngewChem Co., Ltd.

Shanghai AngewChemCo., Ltd. is an innovative enterprise on fine chemicals and pharmaceuticals. Based on Shanghai R&D center and Hunan chemical manufacturing plant, we offer chemical research, process development, and large-scale production. Com

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Nanjing Norris Pharm Technology Co., Ltd.

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemical Technology Co.,LTD

1. Production capacity: we have three production base with high-tech production equipment and instruments, equipped with professional production personnel, meet your requirements.2. Quality assurance: we have a first-class testing equipment and testi

(R)-2-(4-Methoxyphenyl)-1-methylethanamine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Other

inquiry

Shanghai united Scientific Co.,Ltd.

United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat

Benzeneethanamine,4-methoxy-a-methyl-, (aR)-

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chungking Joyinchem Co., Ltd.

Joyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom

Benzeneethanamine,4-methoxy-a-methyl-, (aR)-

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Finetech Industry Limited

FINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the (2R)-1-(4-methoxyphenyl)propan-2-amine, CAS:58993-79-6 with the most competitive pric

(2R)-1-(4-methoxyphenyl)propan-2-amine

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Trading Company

inquiry

LABTER PARMATECH(BEIJING)CO.,LTD

Hight quality, fast shipping, in stock or custom synthesis for the similar compound to meet your need. Storage:standard ambient conditions Package:1g, 5g, 10g, 25g, 50g,100g,500g,1kg,10kg Application:medical intermediate for R&D Transportation:FEDEX,

(R)-2-(4-METHOXYPHENYL)-1-METHYLETHANAMINE

Cas:58993-79-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(R)-1-(4-methoxyphenyl)-N-((R)-1-phenylethyl)propan-2-amine
140173-30-4

(R)-1-(4-methoxyphenyl)-N-((R)-1-phenylethyl)propan-2-amine

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen In methanol at 40℃; for 24h;99.8%
With palladium 10% on activated carbon; hydrogen In methanol at 45℃; under 15201 Torr; for 8h; Autoclave;94%
With palladium 10% on activated carbon at 50℃; under 37503.8 Torr; for 1h;
4-methoxybenzyl methyl ketone
122-84-9

4-methoxybenzyl methyl ketone

2-Pentanone
107-87-9

2-Pentanone

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With Candida boidinii formate dehydrogenase; pyridoxal 5'-phosphate; Aspergillus terreus ω-trans aminase; Lysinibacillus fusiformis leucine dehydrogenase; ammonium formate; nicotinamide adenine dinucleotide In aq. buffer at 30℃; for 24h; pH=8.8; Catalytic behavior; Green chemistry; Enzymatic reaction;A 99.7%
B 99.4%
4-methoxybenzyl methyl ketone
122-84-9

4-methoxybenzyl methyl ketone

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With glucose dehydrogenase; D-Alanine; D-glucose; ω-transaminase ATA-117; pyridoxal 5'-phosphate; nicotinamide adenine dinucleotide; lactate dehydrogenase In dimethyl sulfoxide at 30℃; for 24h; pH=7; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee; stereoselective reaction;99%
With pyridoxal 5'-phosphate; amine transaminase TA-P2-B01; isopropylamine In aq. phosphate buffer at 30℃; for 24h; pH=7.5; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;86%
With Cb-FDH formate dehydrogenase (variant) from Candida boidinii; Rs-PhAmDH amine dehydrogenase variant from the phenylalanine dehydrogenase from Rhodoccoccus species; NAD; ammonium formate In water at 30℃; for 24h; pH=8.5; Reagent/catalyst; Enzymatic reaction; stereoselective reaction;82%
(4R,5S)-5-(4-methoxyphenyl)-4-methyloxazolidin-2-one
957777-98-9

(4R,5S)-5-(4-methoxyphenyl)-4-methyloxazolidin-2-one

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol at 20℃; for 1h; atmospheric pressure;91%
(R)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide
1351781-80-0

(R)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With water; potassium hydroxide Reflux; optical yield given as %ee;70%
C14H23NO2S

C14H23NO2S

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With hydrogenchloride; D-sorbitol; choline chloride In water at 25℃; for 3h;60%
ethyl 2-methoxyacetate
3938-96-3

ethyl 2-methoxyacetate

2-amino-1-(4-methyoxyphenyl)propane
64-13-1

2-amino-1-(4-methyoxyphenyl)propane

A

(R)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide
1351781-80-0

(R)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide

B

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

C

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With Candida antartica lipase B; triethylamine In n-heptane at 50℃; for 25h; Inert atmosphere; Enzymatic reaction; optical yield given as %ee;A 49%
B 40%
C n/a
With Candida antartica lipase B; triethylamine In n-heptane at 35℃; for 1.5h; Inert atmosphere; Enzymatic reaction; optical yield given as %ee;A 38%
B n/a
C n/a
N-[(1R)-2-(4-methoxyphenyl)-1-methylethyl]-N-[(1R)-1-phenylethyl]amine hydrochloride

N-[(1R)-2-(4-methoxyphenyl)-1-methylethyl]-N-[(1R)-1-phenylethyl]amine hydrochloride

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In methanol; water
1-methoxy-4-((E)-2-nitroprop-1-enyl)benzene
37629-51-9

1-methoxy-4-((E)-2-nitroprop-1-enyl)benzene

A

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Stage #1: 1-methoxy-4-((E)-2-nitroprop-1-enyl)benzene With lithium aluminium tetrahydride In diethyl ether for 2h; Reduction; Heating;
Stage #2: With Candida antarctica lipase B; ethyl acetate; triethylamine at 30℃; for 4h; racemate resolution; Title compound not separated from byproducts;
(R)-N-[1-(o-methoxyphenyl)propan-2-yl]ethanamide
86073-42-9

(R)-N-[1-(o-methoxyphenyl)propan-2-yl]ethanamide

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With potassium hydroxide Hydrolysis; Heating;
2-amino-1-(4-methyoxyphenyl)propane
64-13-1

2-amino-1-(4-methyoxyphenyl)propane

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: Candida antarctica lipase B
2: 3M aq. KOH / Heating
View Scheme
Multi-step reaction with 2 steps
1: Candida antartica lipase B; triethylamine / 35 °C / Inert atmosphere; Enzymatic reaction
2: water; potassium hydroxide / Reflux
View Scheme
Multi-step reaction with 2 steps
1: Candida antartica lipase B; triethylamine / n-heptane / 25 h / 50 °C / Inert atmosphere; Enzymatic reaction
2: water; potassium hydroxide / Reflux
View Scheme
Multi-step reaction with 2 steps
1: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
2: water; potassium hydroxide / Reflux
View Scheme
1-methoxy-4-((E)-2-nitroprop-1-enyl)benzene
37629-51-9

1-methoxy-4-((E)-2-nitroprop-1-enyl)benzene

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 78 percent / LiAlH4 / diethyl ether / 2 h / Heating
2: Candida antarctica lipase B
3: 3M aq. KOH / Heating
View Scheme
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

(E/Z)-crotylstannane(1-)*Et4N(1+)

(E/Z)-crotylstannane(1-)*Et4N(1+)

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 81 percent / ammonium acetate / 0.58 h / Heating
2: 78 percent / LiAlH4 / diethyl ether / 2 h / Heating
3: Candida antarctica lipase B
4: 3M aq. KOH / Heating
View Scheme
Multi-step reaction with 2 steps
1.1: 81 percent / ammonium acetate / 0.58 h / Heating
2.1: LiAlH4 / diethyl ether / 2 h / Heating
2.2: Candida antarctica lipase B; ethyl acetate; Et3N / 4 h / 30 °C
View Scheme
l-para-Methoxyamphetamine hydrochloride
50505-80-1

l-para-Methoxyamphetamine hydrochloride

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With ammonia; water In dichloromethane Product distribution / selectivity;
4-methoxybenzyl methyl ketone
122-84-9

4-methoxybenzyl methyl ketone

A

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With glucose dehydrogenase; D-Alanine; D-glucose; ω-transaminase ATA-117; pyridoxal 5'-phosphate; nicotinamide adenine dinucleotide; lactate dehydrogenase In dimethyl sulfoxide at 30℃; for 24h; pH=7; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee; stereoselective reaction;
With Escherichia coli overexpressing ω-transaminase from round 11 variant from Arthrobacter sp.; pyridoxal 5'-phosphate; isopropylamine In dimethyl sulfoxide at 45℃; pH=11; aq. buffer; Enzymatic reaction; optical yield given as %ee;
With pyridoxal 5'-phosphate; isopropylamine In aq. phosphate buffer at 30℃; for 5h; pH=9; Reagent/catalyst; Time; Enzymatic reaction;A n/a
B n/a
butanone
78-93-3

butanone

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With glucose dehydrogenase; D-Alanine; D-glucose; ω-transaminase ATA-117; pyridoxal 5'-phosphate; nicotinamide adenine dinucleotide; lactate dehydrogenase In dimethyl sulfoxide at 30℃; for 24h; pH=7; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee; stereoselective reaction;
N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide
1352411-20-1

N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide

A

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With water; potassium hydroxide Reflux; optical yield given as %ee;
4-(2-nitro-propenyl)-anisole
17354-63-1

4-(2-nitro-propenyl)-anisole

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
2: Candida antartica lipase B; triethylamine / 35 °C / Inert atmosphere; Enzymatic reaction
3: water; potassium hydroxide / Reflux
View Scheme
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
2: Candida antartica lipase B; triethylamine / 35 °C / Inert atmosphere; Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
2: Candida antartica lipase B; triethylamine / n-heptane / 25 h / 50 °C / Inert atmosphere; Enzymatic reaction
View Scheme
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
2: Candida antartica lipase B; triethylamine / n-heptane / 25 h / 50 °C / Inert atmosphere; Enzymatic reaction
3: water; potassium hydroxide / Reflux
View Scheme
Multi-step reaction with 3 steps
1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
2: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
3: water; potassium hydroxide / Reflux
View Scheme
2-amino-1-(4-methyoxyphenyl)propane
64-13-1

2-amino-1-(4-methyoxyphenyl)propane

ethyl acetate
141-78-6

ethyl acetate

A

(S)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide

(S)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide

B

(R)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide
1351781-80-0

(R)-N-[2-(4'-methoxyphenyl)-1-methylethyl]-2-methoxyacetamide

C

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

D

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With Candida antartica lipase B; triethylamine at 35℃; Inert atmosphere; Enzymatic reaction; optical yield given as %ee;
4-methoxy-benzaldehyde
123-11-5

4-methoxy-benzaldehyde

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: ammonium acetate / Reflux
2: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
3: Candida antartica lipase B; triethylamine / 35 °C / Inert atmosphere; Enzymatic reaction
4: water; potassium hydroxide / Reflux
View Scheme
Multi-step reaction with 3 steps
1: ammonium acetate / Reflux
2: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
3: Candida antartica lipase B; triethylamine / 35 °C / Inert atmosphere; Enzymatic reaction
View Scheme
Multi-step reaction with 3 steps
1: ammonium acetate / Reflux
2: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
3: Candida antartica lipase B; triethylamine / n-heptane / 25 h / 50 °C / Inert atmosphere; Enzymatic reaction
View Scheme
Multi-step reaction with 4 steps
1: ammonium acetate / Reflux
2: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
3: triethylamine / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
4: water; potassium hydroxide / Reflux
View Scheme
Multi-step reaction with 4 steps
1: ammonium acetate / Reflux
2: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux
3: Candida antartica lipase B; triethylamine / n-heptane / 25 h / 50 °C / Inert atmosphere; Enzymatic reaction
4: water; potassium hydroxide / Reflux
View Scheme
[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-amine

[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-amine

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: L-Tartaric acid / ethanol
2: palladium 10% on activated carbon; hydrogen / methanol / 24 h / 40 °C / 1.5 MPa
View Scheme
1-(4-methoxyphenyl)propan-2-ol
131029-01-1, 30314-64-8

1-(4-methoxyphenyl)propan-2-ol

A

4-methoxybenzyl methyl ketone
122-84-9

4-methoxybenzyl methyl ketone

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With amine dehydrogenase ChiAmDH; secondary alcohol dehydrogenase from Thermoanaerobacter ethanolicus W110A/G198D mutant; nicotinamide adenine dinucleotide; ammonium chloride pH=9; Enzymatic reaction; enantioselective reaction;A n/a
B n/a
N-(1-(R)-phenylethyl)propan-1-(4-methoxyphenyl)-2-imine

N-(1-(R)-phenylethyl)propan-1-(4-methoxyphenyl)-2-imine

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: trichlorosilane; (8S,9S)-9-picolinamide(9-desoxy)-epi-cinchonidine / dichloromethane / 36 h / -20 °C / Inert atmosphere
2: palladium 10% on activated carbon / 1 h / 50 °C / 37503.8 Torr
View Scheme
N-(2-methylpropane-2-sulfinamide)-propan-1-(4-(methoxy)phenyl)-1-imine

N-(2-methylpropane-2-sulfinamide)-propan-1-(4-(methoxy)phenyl)-1-imine

A

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
With (8S,9S)-9-picolinamide(9-desoxy)-epi-cinchonidine; trichlorosilane In dichloromethane for 0.5h; Flow reactor; Overall yield = 70 %; enantioselective reaction;A n/a
B n/a
inden-1-one
83-33-0

inden-1-one

A

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: titanium(IV) isopropylate / toluene / 0.08 h / Inert atmosphere
1.2: 18 h / 110 °C
2.1: trichlorosilane; (8S,9S)-9-picolinamide(9-desoxy)-epi-cinchonidine / dichloromethane / 0.5 h / Flow reactor
View Scheme
(+)-(R)-N-(1-phenylethyl)-N-[1-(p-methoxyphenyl)-2-propyl]amine hydrochloride

(+)-(R)-N-(1-phenylethyl)-N-[1-(p-methoxyphenyl)-2-propyl]amine hydrochloride

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: hydrogen / palladium 10% on activated carbon / methanol / 8 - 10 h / 50 °C
1.2: pH 1 - 2
2.1: ammonia; water / dichloromethane
View Scheme
Estragole
140-67-0

Estragole

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium 2,2,2-trifluoroacetate; iron(III) chloride; palladium(II) trifluoroacetate / acetonitrile; water / 30 °C / Inert atmosphere; Darkness
2: pyridoxal 5'-phosphate; isopropylamine; amine transaminase TA-P2-B01 / aq. phosphate buffer / 24 h / 30 °C / pH 7.5 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: iron(III) chloride; palladium(II) trifluoroacetate / water / 24 h / 60 °C / Inert atmosphere
2: pyridoxal 5'-phosphate; isopropylamine; amine transaminase TA-P2-B01 / aq. phosphate buffer / 24 h / 30 °C / pH 7.5 / Enzymatic reaction
View Scheme
Estragole
140-67-0

Estragole

A

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine
58993-78-5

(S)-2-(4-methoxy-phenyl)-1-methyl-ethylamine

B

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium 2,2,2-trifluoroacetate; iron(III) chloride; palladium(II) trifluoroacetate / acetonitrile; water / 30 °C / Inert atmosphere; Darkness
2: pyridoxal 5'-phosphate; isopropylamine; amine transaminase ATA-415 / aq. phosphate buffer / 24 h / 30 °C / pH 7.5 / Enzymatic reaction
View Scheme
Multi-step reaction with 2 steps
1: iron(III) chloride; palladium(II) trifluoroacetate / water / 24 h / 60 °C / Inert atmosphere
2: pyridoxal 5'-phosphate; isopropylamine; amine transaminase ATA-415 / aq. phosphate buffer / 24 h / 30 °C / pH 7.5 / Enzymatic reaction
View Scheme
C13H19NO2S

C13H19NO2S

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: D-sorbitol; choline chloride / 0.03 h / 25 °C
2: D-sorbitol; choline chloride; hydrogenchloride / water / 3 h / 25 °C
View Scheme
Multi-step reaction with 2 steps
1: D-sorbitol; choline chloride / 0.03 h / 25 °C
2: D-sorbitol; choline chloride; hydrogenchloride / water / 3 h / 25 °C
View Scheme
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

chloroacetyl chloride
79-04-9

chloroacetyl chloride

R(-)-chloro-N-[2-(4-methoxyphenyl)-1-methylethyl]acetamide

R(-)-chloro-N-[2-(4-methoxyphenyl)-1-methylethyl]acetamide

Conditions
ConditionsYield
With triethylamine In chloroform at 0 - 5℃; for 22 - 26h;95%
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

benzaldehyde
100-52-7

benzaldehyde

(R)-(-)-1-(4'-methoxyphenyl)-2-benzylaminopropane
67346-60-5

(R)-(-)-1-(4'-methoxyphenyl)-2-benzylaminopropane

Conditions
ConditionsYield
With platinum on carbon; hydrogen In toluene at 80℃; under 3800.26 Torr; for 14h; Autoclave;91%
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-1-(4-methoxyphenyl)-2-benzenesulfonylaminopropane

(R)-1-(4-methoxyphenyl)-2-benzenesulfonylaminopropane

Conditions
ConditionsYield
With sodium hydrogencarbonate; benzenesulfonyl chloride In dichloromethane; water88.6%
With sodium hydrogencarbonate; benzenesulfonyl chloride In dichloromethane; water88.6%
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

propargyl bromide
106-96-7

propargyl bromide

(R)-N-(1-(4-methoxyphenyl)propan-2-yl)prop-2-yn-1-amine
1430326-04-7

(R)-N-(1-(4-methoxyphenyl)propan-2-yl)prop-2-yn-1-amine

Conditions
ConditionsYield
With potassium carbonate In toluene; acetonitrile at 20℃; for 16h; Inert atmosphere;60.6%
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diol
210239-94-4

(2R,3R,4S,5R)-2-(6-amino-2-chloro-9H-purin-9-yl)-5-(2-ethyl-2H-tetrazol-5-yl)tetrahydrofuran-3,4-diol

2-[1-(R)-methyl-2-(4-methoxyphenyl)ethylamino]-5’-(2-ethyl-2H-tetrazol-5-yl)adenosine

2-[1-(R)-methyl-2-(4-methoxyphenyl)ethylamino]-5’-(2-ethyl-2H-tetrazol-5-yl)adenosine

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 145℃; for 23h; Inert atmosphere;30%
R-(+)-α-trifluoromethyl-α-methoxy-phenylacetic acid
20445-31-2

R-(+)-α-trifluoromethyl-α-methoxy-phenylacetic acid

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-3,3,3-Trifluoro-2-methoxy-N-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-2-phenyl-propionamide

(R)-3,3,3-Trifluoro-2-methoxy-N-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-2-phenyl-propionamide

Conditions
ConditionsYield
(i) SOCl2, (ii) /BRN= 3030840/, Py, CHCl3; Multistep reaction;
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-1-(3-Chloro-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol
176589-72-3

(R)-1-(3-Chloro-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

Conditions
ConditionsYield
With hydrogenchloride; N-Trimethylsilylacetamide 1.) 110 deg C, 2.) EtOAc, 0 deg C to room temp.; Yield given. Multistep reaction;
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

4-Chloro-pyridine-3-sulfonic acid [(S)-2-[4-(2-fluoro-ethyl)-piperidin-1-yl]-1-(4-nitro-benzyl)-2-oxo-ethyl]-amide
221624-33-5

4-Chloro-pyridine-3-sulfonic acid [(S)-2-[4-(2-fluoro-ethyl)-piperidin-1-yl]-1-(4-nitro-benzyl)-2-oxo-ethyl]-amide

4-[(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamino]-pyridine-3-sulfonic acid [(S)-2-[4-(2-fluoro-ethyl)-piperidin-1-yl]-1-(4-nitro-benzyl)-2-oxo-ethyl]-amide

4-[(R)-2-(4-Methoxy-phenyl)-1-methyl-ethylamino]-pyridine-3-sulfonic acid [(S)-2-[4-(2-fluoro-ethyl)-piperidin-1-yl]-1-(4-nitro-benzyl)-2-oxo-ethyl]-amide

Conditions
ConditionsYield
In ethanol Heating;
N,O-bis-(trimethylsilyl)-acetamide
10416-59-8

N,O-bis-(trimethylsilyl)-acetamide

(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-1-(4-benzyloxy-3-nitrophenyl)oxirane
188730-94-1

(R)-1-(4-benzyloxy-3-nitrophenyl)oxirane

[(R)-2-(4-Benzyloxy-3-nitro-phenyl)-2-trimethylsilanyloxy-ethyl]-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine

[(R)-2-(4-Benzyloxy-3-nitro-phenyl)-2-trimethylsilanyloxy-ethyl]-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-amine

Conditions
ConditionsYield
In dimethyl sulfoxide at 80℃; for 87h; Addition;
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

2-(3-bromo-5-isoxazolyl)oxirane
76596-56-0

2-(3-bromo-5-isoxazolyl)oxirane

A

1-(3-bromo-isoxazol-5-yl)-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

1-(3-bromo-isoxazol-5-yl)-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

B

1-(3-bromo-isoxazol-5-yl)-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

1-(3-bromo-isoxazol-5-yl)-2-[2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

Conditions
ConditionsYield
With calcium(II) trifluoromethanesulfonate In acetonitrile for 24h; Heating;
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R,R)-formoterol
73573-87-2

(R,R)-formoterol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: dimethylsulfoxide / 87 h / 80 °C
2: neutral Al2O3 (activity III)
3: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
4: 69 percent / pyridine / 6.5 h / 60 °C
5: H2 / 10 percentPd/C / ethanol / 20 °C
View Scheme
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-1-(3-Amino-4-benzyloxy-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol
299964-43-5

(R)-1-(3-Amino-4-benzyloxy-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: dimethylsulfoxide / 87 h / 80 °C
2: neutral Al2O3 (activity III)
3: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
View Scheme
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-1-(4-Benzyloxy-3-nitro-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol
245759-61-9

(R)-1-(4-Benzyloxy-3-nitro-phenyl)-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: dimethylsulfoxide / 87 h / 80 °C
2: neutral Al2O3 (activity III)
View Scheme
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

N-(2-Benzyloxy-5-{(R)-1-hydroxy-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide
408497-91-6

N-(2-Benzyloxy-5-{(R)-1-hydroxy-2-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethylamino]-ethyl}-phenyl)-formamide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dimethylsulfoxide / 87 h / 80 °C
2: neutral Al2O3 (activity III)
3: 67 percent / Fe turnings; 1M aq. HCl / methanol / 0.75 h / Heating
4: 69 percent / pyridine / 6.5 h / 60 °C
View Scheme
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-5-(3-Chloro-phenyl)-3-[(R)-2-(4-hydroxy-phenyl)-1-methyl-ethyl]-oxazolidin-2-one
176495-23-1

(R)-5-(3-Chloro-phenyl)-3-[(R)-2-(4-hydroxy-phenyl)-1-methyl-ethyl]-oxazolidin-2-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 1.) AcNHTMS, 2.) aq. HCl / 1.) 110 deg C, 2.) EtOAc, 0 deg C to room temp.
2: 90 percent / Et3N / CHCl3 / Ambient temperature
3: 81 percent / BBr3 / CH2Cl2 / 0 °C
View Scheme
(R)-(-)-p-methoxyamphetamine
58993-79-6

(R)-(-)-p-methoxyamphetamine

(R)-5-(3-Chloro-phenyl)-3-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-oxazolidin-2-one
176495-21-9

(R)-5-(3-Chloro-phenyl)-3-[(R)-2-(4-methoxy-phenyl)-1-methyl-ethyl]-oxazolidin-2-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1.) AcNHTMS, 2.) aq. HCl / 1.) 110 deg C, 2.) EtOAc, 0 deg C to room temp.
2: 90 percent / Et3N / CHCl3 / Ambient temperature
View Scheme

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