1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:60176-77-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(1R,4S)-CIS-4-ACETOXY-2-CYCLOPENTEN-1-OL CAS:60176-77-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high
Cas:60176-77-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:60176-77-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:60176-77-4
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryhigh purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Other
inquiryR & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Manufacturers
inquiry1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(1R,4S)-CIS-4-ACETOXY-2-CYCLOPENTEN-1-OLCASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Other
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Other
inquiryQuality assurance, stable process and affordable priceAppearance:detailed see specifications Storage:enquiry Package:according to the clients requirement Application:Pharmaceutical intermediates Transportation:Normal Port:chengdu
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Trading Company
inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Trading Company
inquiry1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:60176-77-4
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryUnited Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryJoyinchem have been committed to chemical supply for several years and have built good cooperation records with multinational chemical corporations and importers from all over the world. Our services include:-Spot goods-Contract manufacturing-Custom
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry(1R,4S)-CIS-4-ACETOXY-2-CYCLOPENTEN-1-OLAppearance:yellow to white solid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier li
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Trading Company
inquiryHigh Quality Best Price Storage:Store in dry, dark and ventilated place Application:Chemical Synthesis Intermediate
Known for its best quality and competitve price, this chemicals we offered is widely appreciated by our customers.Appearance:yellow to white solid Storage:keep sealed and keep from direct light Package:According client's requirements Application:Phar
Debyesci is here who supplied several kinds of chemical products to global pharmaceutical, drug discovery, agrochemical and biotechnology industries for four yearsOur key scientific leadership team has gained experience in top research and developmen
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryManufacturer,strong R&D,professional team Storage:Store in a cool, dry place. Store in a tightly closed container. Package:according to your requirement Application:ZhiShang Chemical is owned by ZhiShang Group, is a professional new-type chemicals en
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Trading Company
inquiryCas:60176-77-4
Min.Order:0
Negotiable
Type:Trading Company
inquirymore information,please contact us
Cas:60176-77-4
Min.Order:0
Negotiable
Type:Trading Company
inquirycis-1,4-diacetoxy-2-cyclopentene
A
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
B
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
With methanol; lipase B from Candida antarctica In tert-butyl methyl ether at 5℃; for 16h; Enzymatic reaction; enantioselective reaction; | A n/a B 95% |
With sodium hydroxide; Esterase(porcine liver)PLE In water at 32℃; for 8h; Product distribution; further enzymes; pH=7, phosphate buffer; | |
With N-(2-acetamido)-2-aminoethanesulfonic acid; ethanolamine; 2-amino-2-hydroxymethyl-1,3-propanediol at 37℃; for 8h; Product distribution; antibody of IgG class: 37E8, pH 8.0; Km, Kcat, Ki; var. enzymes and time; |
cis-1,4-diacetoxy-2-cyclopentene
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With sodium hydroxide; phosphate buffer; immobilized porcine liver esterase (PLE, E. C. 3.1.1.1) on Eupergit C at 32℃; for 14h; pH= 7; | 87% |
With sodium hydroxide; sodium phosphate buffer; Trichosporon beigelii (NCIM 3326) In ethanol for 26h; pH=7; Hydrolysis; | 74% |
With Trichosporon beigelii NCIM 3326 In ethanol at 20℃; for 26h; pH=7; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee; | 74% |
vinyl acetate
cis-4-cyclopentene-1,3-diol
A
cis-1,4-diacetoxy-2-cyclopentene
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran for 4h; Ambient temperature; lipase from Mucor sp.; | A 10% B 78% |
With Chirazyme In acetic acid butyl ester for 12h; | A 72% B 22% |
With triethylamine In tetrahydrofuran for 2.5h; Ambient temperature; pancreatin; | A 32% B 65% |
(1R,3S)-(-)-1-acetoxycyclopentan-3-ol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride; triethylamine In tetrahydrofuran | 77% |
With tetrabutyl ammonium fluoride; triethylamine In tetrahydrofuran for 2h; Ambient temperature; | 67% |
With tetrabutyl ammonium fluoride; triethylamine In tetrahydrofuran Inert atmosphere; | 50% |
vinyl acetate
A
cis-1,4-diacetoxy-2-cyclopentene
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
C
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
lipase EC 3.1.1.3 L10 In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity; | A n/a B 76.4% C n/a |
lipase EC 3.1.1.3 QLC In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity; | A n/a B 76.4% C n/a |
lipase EC 3.1.1.3 QL In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity; | A n/a B 75.5% C n/a |
lipase EC 3.1.1.3 QLG In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity; | A n/a B 61.9% C n/a |
pancreatin lipase In water; acetone at 5 - 25℃; for 6.5h; Product distribution / selectivity; | A n/a B 16.5% C n/a |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With pig liver esterase; sodium hydroxide In aq. phosphate buffer for 19h; pH=7; Enzymatic reaction; | 75% |
vinyl acetate
cis-4-cyclopentene-1,3-diol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With Pancreatin; triethylamine In tetrahydrofuran at 20℃; for 3h; | 72% |
With Pancreatin | 72% |
With Pancreatin; triethylamine In tetrahydrofuran; water at 5℃; for 23h; | 70% |
vinyl acetate
cis-4-cyclopentene-1,3-diol
A
cis-1,4-diacetoxy-2-cyclopentene
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
C
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 20℃; for 23h; Enzymatic reaction; enantioselective reaction; | A 25% B 61% C n/a |
vinyl acetate
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 20℃; for 22h; Enzymatic reaction; | 53% |
Isopropenyl acetate
cis-4-cyclopentene-1,3-diol
A
cis-1,4-diacetoxy-2-cyclopentene
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
In various solvent(s) at 50℃; for 72h; Candida antarctica lipase B (Novo SP-435); other meso-diols; enzymatic asymmetrization of meso-2-cycloalken-1,4-diols in organic media; | A n/a B 52% |
In various solvent(s) at 50℃; for 72h; Candida antarctica lipase B (Novo SP-435); Yields of byproduct given; | A n/a B 52% |
Isopropenyl acetate
cis-4-cyclopentene-1,3-diol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
at 50℃; acrylic supported Candida antarctica lipase B; | 50% |
2,2,2-trichloroethyl acetate
cis-4-cyclopentene-1,3-diol
A
cis-1,4-diacetoxy-2-cyclopentene
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
In pyridine for 72h; Ambient temperature; porcine pancreatic lipase; | A 22% B 50% |
With triethylamine In tetrahydrofuran for 5h; Ambient temperature; pancreatin; | A 45% B 48% |
With triethylamine In tetrahydrofuran for 5h; Ambient temperature; pancreatin; | A 45% B 48% |
With triethylamine In tetrahydrofuran for 5h; Mechanism; Ambient temperature; pancreatin; other 2,2,2-trichloroethyl alkanoates; | A 45% B 48% |
2,2,2-trichloroethyl acetate
cis-3-acetoxy-5-hydroxycyclopent-1-ene
A
cis-1,4-diacetoxy-2-cyclopentene
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran for 5h; Ambient temperature; pancreatin; | A 49% B 46% |
vinyl acetate
cis-2-cyclopentenyl-1,4-diol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With Pancreatin; triethylamine In tetrahydrofuran at 20℃; Enzymatic reaction; | 14% |
2,2,2-trichloroethyl acetate
cis-4-cyclopentene-1,3-diol
A
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
B
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
pancreatin/base; |
(1S,4R)-(-)-4-(2'R*-tetrahydropyranyloxy)-2-cyclopentenyl acetate
A
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
B
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In ethanol for 2h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
cyclopenta-1,3-diene
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 65 percent / O2; thiourea; Bengal rose / methanol / 18 h / -35 - 20 °C / Irradiation 2: 72 percent / Et3N; pancreatin / tetrahydrofuran / 3 h / 20 °C View Scheme |
(2-furyl)methyl alcohol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 53 percent / KH2PO4, H3PO4 / H2O / 40 h / 99 °C / pH 4.1 2: 76 percent / PPTs / tetrahydrofuran / 18 h / Ambient temperature 3: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C 4: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 5: p-TsOH / ethanol / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 5 steps 1: 53 percent / KH2PO4, H3PO4 / H2O / 40 h / 99 °C / pH 4.1 2: 72 percent / Et3N, DMAP / tetrahydrofuran / Ambient temperature 3: LiAlH4, LiI, TBSOH / toluene; various solvent(s) / 23 h / -30 - -25 °C 4: 48 percent / Et3N, pancreatin / various solvent(s) / 7 h / Ambient temperature 5: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 5 steps 1: 53 percent / KH2PO4, H3PO4 / H2O / 40 h / 99 °C / pH 4.1 2: 72 percent / Et3N, DMAP / tetrahydrofuran / Ambient temperature 3: LiAlH4, LiI, TBSOH / toluene; various solvent(s) / 23 h / -30 - -25 °C 4: 48 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 5: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme |
4-Hydroxycyclopent-2-enone
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 76 percent / PPTs / tetrahydrofuran / 18 h / Ambient temperature 2: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C 3: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 4: p-TsOH / ethanol / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 4 steps 1: 72 percent / Et3N, DMAP / tetrahydrofuran / Ambient temperature 2: LiAlH4, LiI, TBSOH / toluene; various solvent(s) / 23 h / -30 - -25 °C 3: 48 percent / Et3N, pancreatin / various solvent(s) / 7 h / Ambient temperature 4: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 4 steps 1: 72 percent / Et3N, DMAP / tetrahydrofuran / Ambient temperature 2: LiAlH4, LiI, TBSOH / toluene; various solvent(s) / 23 h / -30 - -25 °C 3: 48 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 4: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme |
4-[(tert-butyldimethylsilyl)oxy]cyclopent-2-enone
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: LiAlH4, LiI, TBSOH / toluene; various solvent(s) / 23 h / -30 - -25 °C 2: 48 percent / Et3N, pancreatin / various solvent(s) / 7 h / Ambient temperature 3: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 3 steps 1: LiAlH4, LiI, TBSOH / toluene; various solvent(s) / 23 h / -30 - -25 °C 2: 48 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 3: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 3 steps 1: lithium aluminium tetrahydride; lithium iodide / toluene; tert-butyl methyl ether / 3 h / -30 °C / Inert atmosphere; Large scale 2: triethylamine; Pancreatin / tert-butyl methyl ether / 7 h / Inert atmosphere; Large scale; Enzymatic reaction 3: triethylamine; tetrabutyl ammonium fluoride / tetrahydrofuran / Inert atmosphere View Scheme |
4-(tetrahydro-pyran-2-yloxy)-cyclopent-2-enone
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: LiAlH4, LiI / various solvent(s); toluene / 0.5 h / -20 - -13 °C 2: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 3: p-TsOH / ethanol / 2 h / Ambient temperature View Scheme |
(+/-)-cis-4-(2'R*-tetrahydropyranyloxy)-2-cyclopentenol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 45 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 2: p-TsOH / ethanol / 2 h / Ambient temperature View Scheme |
cis-(+/-)-4-<<(1,1-dimethylethyl)dimethylsilyl>oxy>-2-cyclopenten-1-ol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 48 percent / Et3N, pancreatin / various solvent(s) / 7 h / Ambient temperature 2: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 2 steps 1: 48 percent / Et3N, pancreatin, vinyl acetate / various solvent(s) / 7 h / Ambient temperature 2: 67 percent / Et3N, TBAF / tetrahydrofuran / 2 h / Ambient temperature View Scheme | |
Multi-step reaction with 2 steps 1: 48 percent / Et3N / various solvent(s) / pancreatin 2: 77 percent / tetrabutylammonium fluoride, Et3N / tetrahydrofuran View Scheme | |
Multi-step reaction with 2 steps 1: triethylamine; Pancreatin / tert-butyl methyl ether / 7 h / Inert atmosphere; Large scale; Enzymatic reaction 2: triethylamine; tetrabutyl ammonium fluoride / tetrahydrofuran / Inert atmosphere View Scheme |
cis-4-cyclopentene-1,3-diol
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
cyclopenta-1,3-diene
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
meso-cis-1,4-diacetoxy-2-cyclopentene
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With sodium hydroxide | |
Multi-step reaction with 2 steps 1: potassium hydrogencarbonate / methanol / Reflux 2: triethylamine; Pancreatin / tetrahydrofuran / 20 °C / Enzymatic reaction View Scheme |
6-oxabicyclo[3.1.0]hex-2-ene
acetic acid
A
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
B
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
With tetrakis(triphenylphosphine) palladium(0); Triethylene glycol dimethyl ether In tetrahydrofuran at 0℃; for 1h; Reagent/catalyst; Solvent; Schlenk technique; Inert atmosphere; Overall yield = 85 %Chromat.; | A n/a B n/a |
3,5-cis-dibromocyclopentene
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: N-benzyl-N,N,N-triethylammonium chloride / tert-butyl alcohol / Reflux 2: potassium hydrogencarbonate / methanol / Reflux 3: triethylamine; Pancreatin / tetrahydrofuran / 20 °C / Enzymatic reaction View Scheme |
cis-1,4-diacetoxy-2-cyclopentene
A
cis-4-cyclopentene-1,3-diol
B
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
C
(1R,4S)-4-hydroxy-2-cyclopentene-1-yl acetate
Conditions | Yield |
---|---|
With pseudomonas fluorescens lipase In hexane; water at 25℃; Reagent/catalyst; Enzymatic reaction; enantioselective reaction; | |
With lipase B from Candida antarctica In aq. phosphate buffer at 20℃; pH=7.5; Solvent; Enzymatic reaction; | A n/a B n/a C n/a |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
methanesulfonyl chloride
(1S,4S)-1-acetoxy-4-methanesulfonyloxy-cyclopent-2-ene
Conditions | Yield |
---|---|
With triethylamine In dichloromethane 1.) 0 deg C to rt, 2.) rt, 6 h; | 100% |
With triethylamine In dichloromethane Ambient temperature; | 100% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
tert-butyldimethylsilyl chloride
(1R,3S)-(-)-1-acetoxycyclopentan-3-ol
Conditions | Yield |
---|---|
With dmap; triethylamine In dichloromethane at 23℃; for 12h; | 99% |
With 1H-imidazole In dichloromethane | 90% |
With 1H-imidazole In N,N-dimethyl-formamide |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
O-(4-methoxybenzyl)-trichloroacetimidate
(1S,4R)-1-acetyloxy-4-(4-methoxyphenylmethoxy)cyclopent-2-ene
Conditions | Yield |
---|---|
With camphor-10-sulfonic acid In dichloromethane; pentane at 0 - 20℃; for 33h; | 99% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
[1-(4-bromo-phenyl)-hexyloxy]-tert-butyl-dimethyl-silane
4-(4-(1-(t-butyldimethylsilyloxy)hexyl)phenyl)-2-cyclopenten-1-ol
Conditions | Yield |
---|---|
Stage #1: [1-(4-bromo-phenyl)-hexyloxy]-tert-butyl-dimethyl-silane With magnesium In tetrahydrofuran Stage #2: (1S,4R)-4-hydroxy-2-cyclopentenyl acetate With lithium chloride In tetrahydrofuran at 0℃; for 1h; | 98% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
(1R,2R,4S,5S)-(-)-2-hydroxy-6-oxabicyclo<3.1.0>hex-4-yl acetate
Conditions | Yield |
---|---|
With 3-chloro-benzenecarboperoxoic acid In dichloromethane for 24h; Ambient temperature; | 96% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
tert-butylchlorodiphenylsilane
Acetic acid (1S,4R)-4-(tert-butyl-diphenyl-silanyloxy)-cyclopent-2-enyl ester
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; | 95% |
N-hydroxyphthalimide
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
(1S,4S)-trans-1-acetoxy-4-(phthalimidooxy)-2-cyclopentene
Conditions | Yield |
---|---|
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran Ambient temperature; | 94% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
benzyl bromide
(1S,4R)-4-(benzyloxy)cyclopent-2-en-1-yl acetate
Conditions | Yield |
---|---|
With silver(l) oxide In dichloromethane at 20℃; for 12h; | 93% |
With silver(l) oxide In dichloromethane at 20℃; Inert atmosphere; | 47.7% |
With silver(l) oxide In dichloromethane at 20℃; for 168.5h; Inert atmosphere; Darkness; | 47.7% |
Benzyloxymethyl chloride
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
(1R,4R)-4-(benzyloxymethyl)cyclopent-2-enol
Conditions | Yield |
---|---|
Stage #1: Benzyloxymethyl chloride With bromine; magnesium; mercury dichloride In tetrahydrofuran at -5℃; for 2.5h; Stage #2: (1S,4R)-4-hydroxy-2-cyclopentenyl acetate In tetrahydrofuran at -20℃; for 0.25h; Further stages.; | 92% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
methyl 2-diazo-2-(dimethoxyphosphoryl)acetate
Conditions | Yield |
---|---|
With dirhodium tetraacetate In benzene for 6h; Molecular sieve; Inert atmosphere; Reflux; | 92% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
2',2',2'-trichloroethyl (E)-3-ethoxyacrylate
Conditions | Yield |
---|---|
With N-Bromosuccinimide In dichloromethane Ambient temperature; | 91% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
(1S,3R)-cis-3-acetoxycyclopentan-1-ol
Conditions | Yield |
---|---|
With sodium tetrahydroborate; hydrogen; nickel(II) acetate tetrahydrate In ethanol under 5171.62 Torr; for 4h; Autoclave; | 87% |
With hydrogen; nickel In ethanol at 15 - 20℃; under 750.06 - 3000.2 Torr; for 5h; | 55% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
(1R,4R)-4-phenylcyclopent-2-enol
Conditions | Yield |
---|---|
In tetrahydrofuran Grignard reaction; | 87% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
A
(1R,4R)-4-[7'-(4-methoxybenzyloxy)heptyl]-2-cyclopenten-1-ol
Conditions | Yield |
---|---|
Stage #1: C15H23BrMgO2 With lithium chloride In tetrahydrofuran at -10℃; for 0.5h; Stage #2: (1S,4R)-4-hydroxy-2-cyclopentenyl acetate In tetrahydrofuran at -10℃; for 3h; | A 81% B n/a |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
phenyl isocyanate
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 23℃; Inert atmosphere; | 81% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
4-Methoxyphenyl isocyanate
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 23℃; Inert atmosphere; | 81% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
2',2'-dichloroethyl (E)-3-ethoxyacrylate
Conditions | Yield |
---|---|
With N-Bromosuccinimide In dichloromethane Ambient temperature; | 77% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
2-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-4,5-dimethyl-[1,3,2]dioxaborolane
A
(1R,4R,1'E,3'S)-4-[{3'-(tert-butyldimethylsilyl)oxy}-1'-octenyl]-2-cyclopenten-1-ol
Conditions | Yield |
---|---|
Stage #1: 2-[(E)-(S)-3-(tert-Butyl-dimethyl-silanyloxy)-oct-1-enyl]-4,5-dimethyl-[1,3,2]dioxaborolane With bis(triphenylphosphine)nickel(II) chloride; n-butyllithium; sodium iodide In tetrahydrofuran; hexane Cooling; Stage #2: (1S,4R)-4-hydroxy-2-cyclopentenyl acetate With tert-butyl isocyanide In tetrahydrofuran; hexane at 20℃; for 3h; Further stages.; | A 76% B 3.6% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
4-nitro-N-(prop-2-yn-1-yl)benzene-1-sulfonamide
Conditions | Yield |
---|---|
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran at 20℃; for 16h; Mitsunobu coupling; | 76% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
t-butyl diazoacetate
cis-(-)-{[(1R,4S)-4-acetoxycyclopent-2-en-1-yl]oxy}acetic acid tert-butyl ester
Conditions | Yield |
---|---|
dirhodium tetraacetate In dichloromethane at 20℃; Inert atmosphere; | 73.7% |
ethyl 3-ethoxyacrylate
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
Conditions | Yield |
---|---|
With N-Bromosuccinimide In dichloromethane Ambient temperature; | 72% |
(1S,4R)-4-hydroxy-2-cyclopentenyl acetate
methyl (E)-3-ethoxy-2-propenoate
Conditions | Yield |
---|---|
With N-Bromosuccinimide In dichloromethane Ambient temperature; | 67% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View