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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Pregn-4-ene-3,20-dione,21-(acetyloxy)-17-hydroxy-

Cas:640-87-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

17α-Hydroxyprogesterone Acetate-21-acetate CAS NO.640-87-9

Cas:640-87-9

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of 17α-Hydroxy-11-deoxycorticosterone-21-acetate Cas 640-87-9 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystalline powder Storage:Coo

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

17α-Hydroxy-11-deoxycorticosterone-21-acetate

Cas:640-87-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Best PurityCAS 640-87-9 with fast shipping

Cas:640-87-9

Min.Order:10 Gram

FOB Price: $146.0 / 176.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Pregn-4-ene-3,20-dione,21-(acetyloxy)-17-hydroxy-

Cas:640-87-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pregn-4-ene-3,20-dione,21-(acetyloxy)-17-hydroxy-

Cas:640-87-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

4-HYDROXY CHOLESTEROL-D7 4-ACETATE(RSA)

Cas:640-87-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Reichstein's substance s 21-acetate

Cas:640-87-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

SHANGHAI T&W PHARMACEUTICAL CO., LTD.

A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc

17alpha-Hydroxyprogesterone-21-acetate

Cas:640-87-9

Min.Order:4 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

CAS Number: 640-87-9 Molecular Formula: C23H32O5 Molecular Weight: 388.5 EINECS number: 211-369-4 Related Categories: Steroids;Intermediates & Fine Chemicals;Pharmaceuticals;Steroidal Intermediates

TIANFUCHEM--High purity REICHSTEIN'S SUBSTANCE S 21-ACETATE factory price

Cas:640-87-9

Min.Order:1 Metric Ton

FOB Price: $20.0

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Reichstein'ssubstanceS21-acetate

Cas:640-87-9

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

17α-Hydroxyprogesterone Acetate-21-acetate

Cas:640-87-9

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Sinoway Industrial Co., Ltd.

1) Specialized in pharmaceutical industry since from 1987 2) ISO 9001:2015 & SGS audited supplier 3) Accept better payment terms : T.T 30-60 days.on the basic of pass SINOSURE credit investigation. 5) We have warehouse in USA with quickly shi

17a,21-dihydroxyprogesterone-21-acetate

Cas:640-87-9

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Vanz Pharm Co.,Ltd

ISO/factory/goodqualityAppearance:off white Storage:Dry,cool place Package:drum Application:active pharmaceutical ingredients Transportation:by air/sea/express Port:shenzhen/shanghai

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

reichstein'S substance S 21-acetate

Cas:640-87-9

Min.Order:0

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:needle-like crystals Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:For medicine , pesticide intermedia

Pregn-4-ene-3,20-dione,21-(acetyloxy)-17-hydroxy-

Cas:640-87-9

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

17α-Hydroxyprogesterone Acetate-21-acetate

Cas:640-87-9

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Koning Pharmchem Co., Ltd.

KONING PHARMCHEM CO., LTD. has committed itself to a strategy of providing a unique service for companies involved in the manufacture of pharmaceuticals, healthcare products, food, cosmetics and other fine chemicals. Our products including but not li

17α-Hydroxyprogesterone Acetate-21-acetate (RSA)

Cas:640-87-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

TIANFU-CHEM REICHSTEIN'S SUBSTANCE S 21-ACETATEAppearance:white powder Storage:room temperature Package:200KG Application:Industrial Grade Transportation:By sea , by air or express

TIANFU-CHEM REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

17α-Hydroxy-11-deoxycorticosterone-21-acetate CAS No.640-87-9

Cas:640-87-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Pregn-4-ene-3,20-dione,21-(acetyloxy)-17-hydroxy- cas 640-87-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Pregn-4-ene-3,20-dione,21-(acetyloxy)-17-hydroxy- cas 640-87-9

Cas:640-87-9

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou ZeErRui Chemical Co., Ltd.

Hangzhou ZeErRui Chemical Co., Ltd. located in Lingang industrial areas, our plant covers an area of 6000 square meters.ZeErRui dedicated to the development, production and marketing of chemicals. We have earned ourselves a good reputation at home an

Reichstein's substance s 21-acetate manufacture

Cas:640-87-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Yuanye Bio-Technology Co., Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:200mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Chemlyte Solutions

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

REICHSTEIN'S SUBSTANCE S 21-ACETATE

Cas:640-87-9

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

Cortexolone
152-58-9

Cortexolone

acetic anhydride
108-24-7

acetic anhydride

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With pyridine at 20℃; for 0.5h;100%
With pyridine
17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

acetic anhydride
108-24-7

acetic anhydride

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Stage #1: 17-hydroxyprogesterone With calcium chloride; calcium oxide In methanol; chloroform for 2h;
Stage #2: acetic anhydride With potassium carbonate; acetic acid In methanol; chloroform; N,N-dimethyl-formamide at 100℃; for 1h;
98%
17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

potassium acetate
127-08-2

potassium acetate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Stage #1: 17-hydroxyprogesterone With pyrrolidine In ethanol at 0 - 50℃;
Stage #2: potassium acetate With acetic acid; potassium iodide In ethanol; acetone at 20 - 60℃;
98%
21-Iodo-17α-hydroxypregn-4-en-3,20-dione
4470-79-5

21-Iodo-17α-hydroxypregn-4-en-3,20-dione

acetic acid
64-19-7

acetic acid

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With triethylamine In acetone for 5h; Heating; Inert atmosphere;97%
Isopropenyl acetate
108-22-5

Isopropenyl acetate

Cortexolone
152-58-9

Cortexolone

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With Rhizopus oryzae lipase immobilized on Lewatit 1600 resin In di-isopropyl ether at 55℃; for 48h; regioselective reaction;91%
17α-hydroxy-21-chloro-4-pregnene-3,20-dione
20380-16-9

17α-hydroxy-21-chloro-4-pregnene-3,20-dione

potassium acetate
127-08-2

potassium acetate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 80℃; for 0.5h;90%
21-bromo-17α-hydroxy-4-pregnene-3,20-dione
20380-17-0

21-bromo-17α-hydroxy-4-pregnene-3,20-dione

potassium acetate
127-08-2

potassium acetate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
In acetone at 50℃; for 1h;86%
Yield given;
3β,17α,21-trihydroxypregn-5-en-20-one 21-acetate
1474-10-8

3β,17α,21-trihydroxypregn-5-en-20-one 21-acetate

A

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

B

Acetic acid 2-((8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester

Acetic acid 2-((8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl ester

Conditions
ConditionsYield
With <(C4Ph4COHOCC4Ph4)(μ-H)><(CO)4Ru2>; acetone at 56℃; for 24h;A 67%
B 28%
17α,21-dihydroxy-4-pregnene-3,20-dione 17-acetate
19357-45-0

17α,21-dihydroxy-4-pregnene-3,20-dione 17-acetate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With potassium acetate In N,N-dimethyl-formamide at 105℃; for 6h;51%
21-acetoxy-20-cyanopregna-4,17(20)-dien-3-one
88261-15-8

21-acetoxy-20-cyanopregna-4,17(20)-dien-3-one

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride In dichloromethane Ambient temperature;28%
17.20βF-dihydroxy-21-acetoxy-pregnen-(4)-one-(3)
39703-74-7

17.20βF-dihydroxy-21-acetoxy-pregnen-(4)-one-(3)

A

Androstenedione
63-05-8

Androstenedione

B

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With chromium(VI) oxide; water; acetic acid at 11℃;
4β-bromo-17-hydroxy-21-acetoxy-5β-pregnanedione-(3.20)
96263-55-7

4β-bromo-17-hydroxy-21-acetoxy-5β-pregnanedione-(3.20)

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With semicarbazide hydrochloride; sodium acetate; acetic acid Erwaermen des Reaktionsgemisches mit Brenztraubensaeure und Natriumacetat unter Zusatz von Wasser;
With sodium acetate; acetic acid; (2,4-dinitro-phenyl)-hydrazine Erwaermen des Reaktionsgemisches mit Brenztraubensaeure unter Zusatz von Chloroform und Wasser;
21-acetoxy-5,6β-dichloro-17-hydroxy-5α-pregnane-3,20-dione
113651-23-3

21-acetoxy-5,6β-dichloro-17-hydroxy-5α-pregnane-3,20-dione

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With chromium dichloride
4β-bromo-17-hydroxy-21-acetoxy-5β-pregnanedione-(3.20)
96263-55-7

4β-bromo-17-hydroxy-21-acetoxy-5β-pregnanedione-(3.20)

semicarbazide hydrochloride
563-41-7

semicarbazide hydrochloride

sodium acetate
127-09-3

sodium acetate

acetic acid
64-19-7

acetic acid

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
anschliessend mit Brenztraubensaeure, Natriumacetat und Wasser;
4β-bromo-17-hydroxy-21-acetoxy-5β-pregnanedione-(3.20)
96263-55-7

4β-bromo-17-hydroxy-21-acetoxy-5β-pregnanedione-(3.20)

sodium acetate
127-09-3

sodium acetate

acetic acid
64-19-7

acetic acid

(2,4-dinitro-phenyl)-hydrazine
119-26-6

(2,4-dinitro-phenyl)-hydrazine

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
anschliessend mit Chloroform, Brenztraubensaeure und Wasser;
potassium acetate
127-08-2

potassium acetate

17α-hydroxy-3-(N-morpholinyl)pregna-3,5-dien-20-one
132950-03-9

17α-hydroxy-3-(N-morpholinyl)pregna-3,5-dien-20-one

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Yield given. Multistep reaction;
17α-21-dihydroxy-5-α-pregnane-3,20-dione
312-99-2

17α-21-dihydroxy-5-α-pregnane-3,20-dione

acetic anhydride
108-24-7

acetic anhydride

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multistep reaction;
17α-acetoxy-21-chloro-4-pregnene-3,20-dione
57273-80-0

17α-acetoxy-21-chloro-4-pregnene-3,20-dione

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With potassium acetate In N,N-dimethyl-formamide at 105℃; for 5h;
21-acetoxy-16α.17-epoxy-pregnene-(4)-dione-(3.20)

21-acetoxy-16α.17-epoxy-pregnene-(4)-dione-(3.20)

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With hydrogen bromide; acetic acid Erwaermen des Reaktionsprodukts mit Aethanol und Raney-Nickel;
17.20βF-dihydroxy-21-acetoxy-pregnen-(4)-one-(3)
39703-74-7

17.20βF-dihydroxy-21-acetoxy-pregnen-(4)-one-(3)

water
7732-18-5

water

acetic acid
64-19-7

acetic acid

CrO3

CrO3

A

Androstenedione
63-05-8

Androstenedione

B

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

methyl 20-cyano-3β-hydroxypregna-5,17(20)-dien-21-oate
88261-10-3

methyl 20-cyano-3β-hydroxypregna-5,17(20)-dien-21-oate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 92 percent / p-TsOH / CH2Cl2 / 1.5 h / Ambient temperature
2: 67 percent / diisobutylaluminium hydride / CH2Cl2; hexane / 0.5 h / -78 °C
3: 83 percent / pyridine / Ambient temperature
4: 95 percent / p-TsOH, MeOH / 0.05 h / 50 °C
5: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating
6: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature
View Scheme
20-cyanopregna-5,17(20)-diene-3β,21-diol 21-acetate
88261-14-7

20-cyanopregna-5,17(20)-diene-3β,21-diol 21-acetate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating
2: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature
View Scheme
20-cyano-3β-tetrahydropyranyloxypregna-5,17(20)-dien-21-ol
88261-12-5

20-cyano-3β-tetrahydropyranyloxypregna-5,17(20)-dien-21-ol

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 83 percent / pyridine / Ambient temperature
2: 95 percent / p-TsOH, MeOH / 0.05 h / 50 °C
3: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating
4: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature
View Scheme
[(3S,8R,9S,10R,13S,14S)-3-Acetoxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-(17E)-ylidene]-cyano-acetic acid ethyl ester

[(3S,8R,9S,10R,13S,14S)-3-Acetoxy-10,13-dimethyl-1,2,3,4,7,8,9,10,11,12,13,14,15,16-tetradecahydro-cyclopenta[a]phenanthren-(17E)-ylidene]-cyano-acetic acid ethyl ester

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: KOH / H2O; tetrahydrofuran / 4 h
2: 92 percent / p-TsOH / CH2Cl2 / 1.5 h / Ambient temperature
3: 67 percent / diisobutylaluminium hydride / CH2Cl2; hexane / 0.5 h / -78 °C
4: 83 percent / pyridine / Ambient temperature
5: 95 percent / p-TsOH, MeOH / 0.05 h / 50 °C
6: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating
7: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature
View Scheme
methyl 20-cyano-3β-tetrahydropyranyloxypregna-5,17(20)-dien-21-oate
88261-11-4

methyl 20-cyano-3β-tetrahydropyranyloxypregna-5,17(20)-dien-21-oate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 67 percent / diisobutylaluminium hydride / CH2Cl2; hexane / 0.5 h / -78 °C
2: 83 percent / pyridine / Ambient temperature
3: 95 percent / p-TsOH, MeOH / 0.05 h / 50 °C
4: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating
5: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature
View Scheme
20-cyano-3β-tetrahydropyranyloxypregna-5,17(20)-dien-21-ol acetate
88261-13-6

20-cyano-3β-tetrahydropyranyloxypregna-5,17(20)-dien-21-ol acetate

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 95 percent / p-TsOH, MeOH / 0.05 h / 50 °C
2: 77 percent / aluminium isopropoxide / toluene; cyclohexanone / 20 h / Heating
3: 28 percent / KMnO4, triethylbenzylammonium chloride (TEBACl) / CH2Cl2 / Ambient temperature
View Scheme
21-Brom-17-(formyloxy)-4-pregnen-3,20-dion
80134-08-3

21-Brom-17-(formyloxy)-4-pregnen-3,20-dion

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq. KHCO3 / methanol
View Scheme
Multi-step reaction with 2 steps
1: 86 percent / KHCO3 / methanol; H2O / 0.5 h / Ambient temperature
2: 86 percent / acetone / 1 h / 50 °C
View Scheme
Epiandrosterone
481-29-8

Epiandrosterone

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
2: (N,N-dimethylamino)pyridine, pyridine
3: 92 percent / PdCl2(CH3CN)2 / tetrahydrofuran / Ambient temperature
4: 1. KOH, 2.) N-bromoacetamide
View Scheme
3β,21-Diacetoxy-5α-pregn-17-ene
74499-15-3

3β,21-Diacetoxy-5α-pregn-17-ene

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 1. KOH, 2.) N-bromoacetamide
View Scheme
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

ethylene glycol
107-21-1

ethylene glycol

21-acetoxy-17α-hydroxy-3,3-ethylenedioxypregn-5-ene-20-one
913-44-0

21-acetoxy-17α-hydroxy-3,3-ethylenedioxypregn-5-ene-20-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid; formic acid ethyl ester at 60℃; for 3h;86%
With toluene-4-sulfonic acid; benzene
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With water; potassium carbonate In methanol at 20℃; for 3h; Inert atmosphere;85%
With methanol; potassium hydrogencarbonate
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

A

Cortexolone
152-58-9

Cortexolone

B

9α-hydroxycortexolone
566-12-1

9α-hydroxycortexolone

Conditions
ConditionsYield
With disodium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; menadione; corn-steep liquor In water; N,N-dimethyl-formamide at 28℃; for 40h; Rhodococcus sp.;A 30%
B 50%
formaldehyd
50-00-0

formaldehyd

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

17α-hydroxy-17β-(1(3)H-imidazol-4-yl)-androst-4-en-3-one

17α-hydroxy-17β-(1(3)H-imidazol-4-yl)-androst-4-en-3-one

Conditions
ConditionsYield
With ammonium hydroxide; copper diacetate In ethanol for 6h; Heating;34%
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

2,2-dimethylpropanoic anhydride
1538-75-6

2,2-dimethylpropanoic anhydride

21-Acetoxy-17-trimethylacetoxy-4-pregnen-3,20-dion
86098-88-6

21-Acetoxy-17-trimethylacetoxy-4-pregnen-3,20-dion

Conditions
ConditionsYield
With dmap In diethylene glycol dimethyl ether at 80℃; for 96h;15%
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

17α-21-dihydroxy-5-α-pregnane-3,20-dione
312-99-2

17α-21-dihydroxy-5-α-pregnane-3,20-dione

Conditions
ConditionsYield
In ethanol at 24 - 26℃; for 96h; Penicillium decumbens ATCC 10436, potato dextrose broth;8%
Multi-step reaction with 4 steps
1: H2SO4 / ethanol; dioxane / 1 h / Ambient temperature
2: H2 / 5percent Pd-C / ethanol; ethyl acetate / 14 h
3: 2N HCl / H2O
4: NaOH / methanol; dioxane
View Scheme
2-ethyl-2-methyl-1,3-dioxolane
126-39-6

2-ethyl-2-methyl-1,3-dioxolane

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

21-acetoxy-17α-hydroxy-3,3-ethylenedioxypregn-5-ene-20-one
913-44-0

21-acetoxy-17α-hydroxy-3,3-ethylenedioxypregn-5-ene-20-one

Conditions
ConditionsYield
With toluene-4-sulfonic acid Entfernen des entstehenden Butanons;
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

semicarbazide hydrochloride
563-41-7

semicarbazide hydrochloride

21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione-3-semicarbazone
118978-39-5

21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione-3-semicarbazone

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

semicarbazide hydrochloride
563-41-7

semicarbazide hydrochloride

21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione disemicarbazone
119186-39-9

21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione disemicarbazone

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate
1249-67-8

17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate

Conditions
ConditionsYield
With selenium(IV) oxide
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

14,17,21-trihydroxy-pregn-4-ene-3,20-dione
595-18-6

14,17,21-trihydroxy-pregn-4-ene-3,20-dione

Conditions
ConditionsYield
mit Hilfe von Mycobacterium smegmatis;
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

17β-acetoxymethyl-17α-hydroxy-D-homo-androst-4-ene-3,17a-dione
100774-07-0

17β-acetoxymethyl-17α-hydroxy-D-homo-androst-4-ene-3,17a-dione

Conditions
ConditionsYield
With cyclohexanone; aluminum isopropoxide; toluene
With boron trifluoride diethyl etherate; acetic anhydride; acetic acid
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

21-acetoxy-17-hydroxy-pregna-4,6-diene-3,20-dione
6723-95-1

21-acetoxy-17-hydroxy-pregna-4,6-diene-3,20-dione

Conditions
ConditionsYield
With chloranil
Multi-step reaction with 2 steps
1: N-bromo-succinimide
2: 2,4,6-trimethyl-pyridine
View Scheme
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

21-acetoxy-6ξ-bromo-17-hydroxy-pregn-4-ene-3,20-dione
117064-36-5

21-acetoxy-6ξ-bromo-17-hydroxy-pregn-4-ene-3,20-dione

Conditions
ConditionsYield
With N-Bromosuccinimide
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione dioxime
119572-37-1

21-acetoxy-17-hydroxy-pregn-4-ene-3,20-dione dioxime

Conditions
ConditionsYield
With hydrogenchloride; hydroxylamine
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

4ξ,21-diacetoxy-5,17-dihydroxy-5ξ-pregnane-3,20-dione

4ξ,21-diacetoxy-5,17-dihydroxy-5ξ-pregnane-3,20-dione

Conditions
ConditionsYield
With osmium(VIII) oxide; dihydrogen peroxide; tert-butyl alcohol Behandeln des Reaktionsprodukts mit Acetanhydrid und Pyridin;
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

17α-hydroxy-17β-(1(3)H-imidazol-4-yl)-androst-4-en-3-one

17α-hydroxy-17β-(1(3)H-imidazol-4-yl)-androst-4-en-3-one

Conditions
ConditionsYield
With formaldehyd; ammonia; copper diacetate

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