Products

Refine

Country

Business Type

Certificate

Display

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

11-Desoxy-17-hydroxycorticosterone

Cas:152-58-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

CAS: 152-58-9 37-60-5 Chemical formula: C21H30O4 Molecular weight: 346.4605 Density: 1.22g/cm3 Melting point: 205-208 ℃ Boiling point: 524.5 ° C at 760 mmHg Flash point: 285.1 ° C Steam pressure: 3.41E-13mmHg at 25 ° C Solubility: Soluble

CORTEXOLONE 152-58-9

Cas:152-58-9

Min.Order:5 Kilogram

FOB Price: $20.0 / 80.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 152-58-9 with competitive price

Cas:152-58-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:off White powder Storage:R.T Package:25kg/drum Application:It is used in biochemical research Transportation:Express/Sea/Air Port:Any port in China

Factory price high quality CORTEXOLONE

Cas:152-58-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Pregn-4-ene-3,20-dione,17,21-dihydroxy-

Cas:152-58-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

CORTEXOLONE CAS:152-58-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

CORTEXOLONE CAS:152-58-9

Cas:152-58-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Pregn-4-ene-3,20-dione,17,21-dihydroxy-

Cas:152-58-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Pregn-4-ene-3,20-dione,17,21-dihydroxy-

Cas:152-58-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

CORTEXOLONE

Cas:152-58-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cortexolone

Cas:152-58-9

Min.Order:0 Metric Ton

Negotiable

Type:Other

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Pregn-4-ene-3,20-dione,17,21-dihydroxy-

Cas:152-58-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

CORTEXOLONE

Cas:152-58-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

11-Deoxy-17-Hydroxycorticosterone manufacturer

Cas:152-58-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hebei Kunsui Technology Co., Ltd.

1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m

Pharmaceutical Cortodoxone Powder CAS 152-58-9

Cas:152-58-9

Min.Order:1 Kilogram

FOB Price: $8.2 / 8.8

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

152-58-9 CORTEXOLONE

Cas:152-58-9

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

CORTEXOLONE

Cas:152-58-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Product name: CORTEXOLONE CAS No.: 152-58-9 Chemical name: (8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one;Hydrocortisone Impurity 6

CORTEXOLONE

Cas:152-58-9

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Cortexolone

Cas:152-58-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

Appearance:Solid powder Storage:Sealed,light and oxygen resistant Package:Foil bag or drum Application:Applied in dietary supplements,pharmaceutical or cosmeticeuticals Transportation:by sea or air Port:Beijing or Guangzhou Port

Cortodoxone

Cas:152-58-9

Min.Order:0

Negotiable

Type:Other

inquiry

DB BIOTECH CO., LTD

Q1: Are you a manufacturer Answer: Yes, we are factory founded on 2012.Q2: How to contact with us Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours.Q3:Which kind of payment terms do you

CORTEXOLONE

Cas:152-58-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Cortodoxone C54460 20mg

Cas:152-58-9

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Cortexolone

Cas:152-58-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xi`an Eastling Biotech Co., Ltd.

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:Beijing or Guangzhou

CORTEXOLONE

Cas:152-58-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

High qualityAppearance:White powder Storage:Room temperature Package:Aluminum bag Application:Used in producing API Transportation:By air Port:Beijing

Cortexolone

Cas:152-58-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Pregn-4-ene-3,20-dione,17,21-dihydroxy-

Cas:152-58-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

HANGZHOU TIANYE CHEMICALS CO., LTD.

We product this chemical more than 10 years . We are very experience to export it to many countries, Our superior & stable quality , competitive price gain warm reception from our customers. Application:Pharm intermediate

CORTEXOLONE

Cas:152-58-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:25kg,50kg,180kg,200kg,250kg,1000kg,customization Application:Pharma;Industry;Agricultural;chemical reaserch Tran

(8R,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-

Cas:152-58-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use as primary and sec

4-Pregnen-17α,21-diol-3,20-dione-21,21-d2

Cas:152-58-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Cortodoxone cas 152-58-9Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Cortodoxone cas 152-58-9

Cas:152-58-9

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

CORTEXOLONE

Cas:152-58-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(8R,9S,10R,13S,14S)-10,13-Dimethyl-17-[1-tripropylsilanyloxy-eth-(Z)-ylidene]-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
110801-53-1

(8R,9S,10R,13S,14S)-10,13-Dimethyl-17-[1-tripropylsilanyloxy-eth-(Z)-ylidene]-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With potassium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid88%
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With water; potassium carbonate In methanol at 20℃; for 3h; Inert atmosphere;85%
With methanol; potassium hydrogencarbonate
17,21-diacetoxy-4-pregnene-3,20-dione
1807-15-4

17,21-diacetoxy-4-pregnene-3,20-dione

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With potassium hydroxide In methanol Ambient temperature;80%
With potassium hydroxide
C25H37BrNO2(1+)*Cl(1-)

C25H37BrNO2(1+)*Cl(1-)

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With water; potassium carbonate In acetone at 20℃; for 72h; Inert atmosphere;70%
21-bromo-17α-hydroxy-4-pregnene-3,20-dione
20380-17-0

21-bromo-17α-hydroxy-4-pregnene-3,20-dione

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With potassium carbonate for 0.166667h; Heating;68%
With water; potassium carbonate In acetone at 20℃; for 0.5h; Inert atmosphere;57%
cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

A

Cortexolone
152-58-9

Cortexolone

B

9α-hydroxycortexolone
566-12-1

9α-hydroxycortexolone

Conditions
ConditionsYield
With disodium hydrogenphosphate; potassium dihydrogenphosphate; D-glucose; menadione; corn-steep liquor In water; N,N-dimethyl-formamide at 28℃; for 40h; Rhodococcus sp.;A 30%
B 50%
pyridine
110-86-1

pyridine

17.20βF-dihydroxy-3-oxo-pregnen-(4)-al-(21)
59005-57-1

17.20βF-dihydroxy-3-oxo-pregnen-(4)-al-(21)

Cortexolone
152-58-9

Cortexolone

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
mit Hilfe von Trichothecium roseum;
21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

A

Cortexolone
152-58-9

Cortexolone

B

6β,21-dihydroxypregna-4-en-3,20-dione
298-65-7

6β,21-dihydroxypregna-4-en-3,20-dione

Conditions
ConditionsYield
mit Hilfe von Trichothecium roseum;
17.20βF-dihydroxy-3-oxo-pregnen-(4)-al-(21)
59005-57-1

17.20βF-dihydroxy-3-oxo-pregnen-(4)-al-(21)

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With pyridine
Progesterone
57-83-0

Progesterone

A

HYDROCORTISONE
50-23-7

HYDROCORTISONE

B

17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

C

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

D

Corticosterone
50-22-6

Corticosterone

E

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With glucose-6-phosphate dehydrogenase; phosphate buffer; air; α-D-glucose 6-phosphate; midterm female fetal human adrenal tissue; NADP; magnesium chloride at 37℃; for 2h; Product distribution; <3H>labeled;A 36.3 % Chromat.
B n/a
C n/a
D 4.7 % Chromat.
E n/a
Progesterone
57-83-0

Progesterone

A

17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

B

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

C

Corticosterone
50-22-6

Corticosterone

D

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With glucose-6-phosphate dehydrogenase; phosphate buffer; air; α-D-glucose 6-phosphate; midterm female fetal human kidney tissue; NADP; magnesium chloride at 37℃; for 2h; Product distribution; <3H>labeled;A 2.3 % Chromat.
B 21.1 % Chromat.
C n/a
D 32.5 % Chromat.
17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

A

HYDROCORTISONE
50-23-7

HYDROCORTISONE

B

testosterone
58-22-0

testosterone

C

Androstenedione
63-05-8

Androstenedione

D

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With D-glucose 6-phosphate; sporadic adrenal pheochromocytomas; oxygen; NADP; glucose 6-phosphate dehydrogenase at 37℃; for 1h; Product distribution; <4-14C>-labeled;A 20.6 % Turnov.
B 1.1 % Turnov.
C 2.3 % Turnov.
D 14.8 % Turnov.
17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
With α-D-glucose 6-phosphate; 21-hydroxylase from human fetal adrenals; glucose-6-phosphate-dehydrogenase; potassium chloride; 2-amino-2-hydroxymethyl-1,3-propanediol; magnesium chloride Equilibrium constant; interaction with cytochrome P-450 obtained from microsomes and mitochondria from human fetal adrenals in dependence on conc.; apparent spectral dissociation const.; inhibition by danazol;
With CYP21 Enzymatic reaction;
With recombinant human cytochrome P450 21A2; water In aq. phosphate buffer at 37℃; Enzymatic reaction;
With wild-type human cytochrome P450 21A2 Kinetics; Reagent/catalyst; Enzymatic reaction;
methanol
67-56-1

methanol

16α,17α-epoxyprogesterone
1097-51-4, 16356-47-1

16α,17α-epoxyprogesterone

A

Cortexolone
152-58-9

Cortexolone

B

20,20-dimethoxy-16α,17α-epoxypregn-4-en-21-ol-3-one
119005-10-6

20,20-dimethoxy-16α,17α-epoxypregn-4-en-21-ol-3-one

Conditions
ConditionsYield
With potassium hydroxide; [bis(acetoxy)iodo]benzene at 20℃; for 7h;A 0.08 g
B 0.15 g
16α,17α-epoxyprogesterone
1097-51-4, 16356-47-1

16α,17α-epoxyprogesterone

A

17-hydroxyprogesterone
68-96-2

17-hydroxyprogesterone

B

Cortexolone
152-58-9

Cortexolone

C

16α,17α-epoxypregn-4-en-21-ol-3,20-dione
100167-82-6

16α,17α-epoxypregn-4-en-21-ol-3,20-dione

Conditions
ConditionsYield
With potassium hydroxide; [bis(acetoxy)iodo]benzene In methanol at 20℃; for 8h;A 0.02 g
B 0.02 g
C 0.19 g
Pregnenolone
145-13-1

Pregnenolone

A

HYDROCORTISONE
50-23-7

HYDROCORTISONE

B

testosterone
58-22-0

testosterone

C

Androstenedione
63-05-8

Androstenedione

D

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

E

Corticosterone
50-22-6

Corticosterone

F

Cortexolone
152-58-9

Cortexolone

G

DHEA

DHEA

Conditions
ConditionsYield
With D-glucose 6-phosphate; sporadic adrenal pheochromocytomas; oxygen; NADP; glucose 6-phosphate dehydrogenase at 37℃; for 1h; Product distribution; <4-14C>-labeled;A 12.6 % Turnov.
B 0.9 % Turnov.
C 1.9 % Turnov.
D 2.4 % Turnov.
E 6.8 % Turnov.
F 2.3 % Turnov.
G n/a
C26H37NO5

C26H37NO5

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 80 percent
2: hydrolysis
3: 80 percent / KOH / methanol / Ambient temperature
View Scheme
C28H39NO7
84542-27-8

C28H39NO7

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: hydrolysis
2: 80 percent / KOH / methanol / Ambient temperature
View Scheme
17-Hydroxypregnenolone
387-79-1

17-Hydroxypregnenolone

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 10 percent / CuBr2 / tetrahydrofuran / 2 h / Heating
2: 65 percent / 8 N CrO3 / acetone / 0.08 h
3: 68 percent / aq. K2CO3 / 0.17 h / Heating
View Scheme
21-bromo-3β,17α-dihydroxy-5-pregnen-20-one
2827-40-9

21-bromo-3β,17α-dihydroxy-5-pregnen-20-one

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 65 percent / 8 N CrO3 / acetone / 0.08 h
2: 68 percent / aq. K2CO3 / 0.17 h / Heating
View Scheme
16-dehydroprogesterone
1096-38-4

16-dehydroprogesterone

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 79 percent / RhCl(PPh3)3
2: 88 percent / mCPBA, KHCO3
View Scheme
17-hydroxy-20βF-acetoxy-3-oxo-pregnen-(4)-al-(21)

17-hydroxy-20βF-acetoxy-3-oxo-pregnen-(4)-al-(21)

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aqueous methanol.KHCO3
2: pyridine
View Scheme
Progesterone
57-83-0

Progesterone

A

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

B

2β,16β-hydroxyprogesterone
1334177-12-6

2β,16β-hydroxyprogesterone

C

Cortexolone
152-58-9

Cortexolone

E

2beta-Hydroxyprogesterone
604-29-5, 604-28-4, 123287-83-2

2beta-Hydroxyprogesterone

Conditions
ConditionsYield
With Bacillus megaterium cytochrome P450 BM3 monooxygenase (V78L/A82F/F87A)-expressing cells at 25℃; for 24h; diastereoselective reaction;
Progesterone
57-83-0

Progesterone

A

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

B

Cortexolone
152-58-9

Cortexolone

D

2beta-Hydroxyprogesterone
604-29-5, 604-28-4, 123287-83-2

2beta-Hydroxyprogesterone

Conditions
ConditionsYield
With Bacillus megaterium cytochrome P450 BM3 monooxygenase (R47Y/T49F/V78T/A82F/F78A)-expressing cells at 25℃; for 24h; diastereoselective reaction;
Progesterone
57-83-0

Progesterone

Cortexolone
152-58-9

Cortexolone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: CYP17A1 / Enzymatic reaction
2: CYP21 / Enzymatic reaction
View Scheme
3-O-ethoxypregnenolone

3-O-ethoxypregnenolone

A

Androstenedione
63-05-8

Androstenedione

B

Cortexolone
152-58-9

Cortexolone

C

R-16α,17-dihydroxy-pregn-4-ene-3,20-dione
595-77-7

R-16α,17-dihydroxy-pregn-4-ene-3,20-dione

D

C21H30O5

C21H30O5

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium tert-butylate; oxygen / tetrahydrofuran; tert-butyl alcohol / 4.67 h / 20 °C
2: acetic acid / methanol / 3 h / 20 °C
3: 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; zebrafish P450 17A2 enzyme / aq. phosphate buffer; ethanol; dimethyl sulfoxide / 37 °C / pH 7.4 / Enzymatic reaction
4: zebrafish P450 17A1 enzyme; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine / aq. phosphate buffer / 37 °C / pH 7.4 / Enzymatic reaction
View Scheme
3-O-ethoxypregnenolone

3-O-ethoxypregnenolone

A

Cortexolone
152-58-9

Cortexolone

B

R-16α,17-dihydroxy-pregn-4-ene-3,20-dione
595-77-7

R-16α,17-dihydroxy-pregn-4-ene-3,20-dione

C

C21H30O5

C21H30O5

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: potassium tert-butylate; oxygen / tetrahydrofuran; tert-butyl alcohol / 4.67 h / 20 °C
2: acetic acid / methanol / 3 h / 20 °C
3: 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; zebrafish P450 17A2 enzyme / aq. phosphate buffer; ethanol; dimethyl sulfoxide / 37 °C / pH 7.4 / Enzymatic reaction
4: 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; zebrafish b5 enzyme; NADPH-P450 reductase; zebrafish P450 17A2 enzyme / aq. phosphate buffer / 37 °C / pH 7.4 / Enzymatic reaction
View Scheme
C23H36O4

C23H36O4

A

Androstenedione
63-05-8

Androstenedione

B

Cortexolone
152-58-9

Cortexolone

C

R-16α,17-dihydroxy-pregn-4-ene-3,20-dione
595-77-7

R-16α,17-dihydroxy-pregn-4-ene-3,20-dione

D

C21H30O5

C21H30O5

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: acetic acid / methanol / 3 h / 20 °C
2: 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine; zebrafish P450 17A2 enzyme / aq. phosphate buffer; ethanol; dimethyl sulfoxide / 37 °C / pH 7.4 / Enzymatic reaction
3: zebrafish P450 17A1 enzyme; 1,2-dilauroyl-sn-glicero-3-phosphatidylcholine / aq. phosphate buffer / 37 °C / pH 7.4 / Enzymatic reaction
View Scheme
Cortexolone
152-58-9

Cortexolone

acetic anhydride
108-24-7

acetic anhydride

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With pyridine at 20℃; for 0.5h;100%
With pyridine
Cortexolone
152-58-9

Cortexolone

21-dehydrohydrocortexolone dimer

21-dehydrohydrocortexolone dimer

Conditions
ConditionsYield
With air; copper diacetate In methanol for 5h;100%
Cortexolone
152-58-9

Cortexolone

pivaloyl chloride
3282-30-2

pivaloyl chloride

17-Hydroxy-21-trimethylacetoxy-4-pregnen-3,20-dion
6920-52-1

17-Hydroxy-21-trimethylacetoxy-4-pregnen-3,20-dion

Conditions
ConditionsYield
With dmap In pyridine at 0℃; for 2h;99%
With pyridine; dichloromethane
Cortexolone
152-58-9

Cortexolone

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

17α-hydroxy-21-<(methylsulfonyl)oxy>pregn-4-ene-3,20-dione
82427-84-7

17α-hydroxy-21-<(methylsulfonyl)oxy>pregn-4-ene-3,20-dione

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 1h;97%
triethylsilane
617-86-7

triethylsilane

Cortexolone
152-58-9

Cortexolone

17-hydroxy-21-(triethylsiloxy)pregn-4-ene-3,20-dione

17-hydroxy-21-(triethylsiloxy)pregn-4-ene-3,20-dione

Conditions
ConditionsYield
AuCl(xanthphos) In chloroform; N,N-dimethyl-formamide at 50℃; for 6h;96%
Cortexolone
152-58-9

Cortexolone

17,21,21-trihydroxy-4-pregnene-3,20-dione
84869-31-8

17,21,21-trihydroxy-4-pregnene-3,20-dione

Conditions
ConditionsYield
With copper diacetate; air In methanol for 7h; Ambient temperature;95%
Cortexolone
152-58-9

Cortexolone

11β,20-dihydroxy-3-oxo-4,cis-17(20)-pregnadien-21-al
105562-13-8

11β,20-dihydroxy-3-oxo-4,cis-17(20)-pregnadien-21-al

Conditions
ConditionsYield
With oxone; 2-Iodobenzoic acid In dimethyl sulfoxide at 75℃; for 12h; Inert atmosphere;92%
Cortexolone
152-58-9

Cortexolone

20-hydroxy-3,11-dioxo-4,cis-17(20)-pregnadien-21-al
118916-30-6

20-hydroxy-3,11-dioxo-4,cis-17(20)-pregnadien-21-al

Conditions
ConditionsYield
With oxone; 2-Iodobenzoic acid In dimethyl sulfoxide at 75℃; for 12h; Inert atmosphere;92%
Isopropenyl acetate
108-22-5

Isopropenyl acetate

Cortexolone
152-58-9

Cortexolone

cortexolone 21-acetate
640-87-9

cortexolone 21-acetate

Conditions
ConditionsYield
With Rhizopus oryzae lipase immobilized on Lewatit 1600 resin In di-isopropyl ether at 55℃; for 48h; regioselective reaction;91%
Cortexolone
152-58-9

Cortexolone

20-hydroxy-3-oxo-4,cis-17(20)-pregnadien-21-al
118864-85-0

20-hydroxy-3-oxo-4,cis-17(20)-pregnadien-21-al

Conditions
ConditionsYield
With oxone; 2-Iodobenzoic acid In dimethyl sulfoxide at 75℃; for 12h; Inert atmosphere;89%
Cortexolone
152-58-9

Cortexolone

2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

(8R,10R,13S,14S,17R)-17-(2-(benzo[d]thiazol-2-ylthio)acetyl)-17-hydroxy-10,13-dimethyl1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

(8R,10R,13S,14S,17R)-17-(2-(benzo[d]thiazol-2-ylthio)acetyl)-17-hydroxy-10,13-dimethyl1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3H-cyclopenta[a]phenanthren-3-one

Conditions
ConditionsYield
With fluorosulfonyl fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 0.166667h;88%
hexanes-ethyl acetate

hexanes-ethyl acetate

Cortexolone
152-58-9

Cortexolone

methyl 17α-hydroxy-3-oxoandrost-4-ene-17-carboxylate
10486-86-9

methyl 17α-hydroxy-3-oxoandrost-4-ene-17-carboxylate

Conditions
ConditionsYield
With sulfuric acid; sodium hydrogencarbonate In methanol87%
Cortexolone
152-58-9

Cortexolone

Androstenedione
63-05-8

Androstenedione

Conditions
ConditionsYield
In water; acetonitrile at 20℃; Electrochemical reaction;86%
With ammonium hydroxide; iodine In water; acetonitrile at 50℃; for 24h;78%
With manganese(IV) oxide In chloroform for 4h; Heating;67.6%
Cortexolone
152-58-9

Cortexolone

Bestmann ylide
73818-55-0, 15596-07-3

Bestmann ylide

4-((8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one
18104-63-7

4-((8R,9S,10R,13S,14S,17R)-17-Hydroxy-10,13-dimethyl-3-oxo-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-5H-furan-2-one

Conditions
ConditionsYield
In benzene for 3h; Heating;86%
Cortexolone
152-58-9

Cortexolone

methanesulfonyl chloride
124-63-0

methanesulfonyl chloride

17α-hydroxy-21-chloro-4-pregnene-3,20-dione
20380-16-9

17α-hydroxy-21-chloro-4-pregnene-3,20-dione

Conditions
ConditionsYield
With dmap In dichloromethane for 4h; Reflux;85%
Cortexolone
152-58-9

Cortexolone

17α-hydroxyandrost-4-en-3-one-17β-carboxylic acid
633-29-4

17α-hydroxyandrost-4-en-3-one-17β-carboxylic acid

Conditions
ConditionsYield
With sodium periodate In tetrahydrofuran; methanol at 20℃; for 2h;82%
With methanol; periodic acid
With periodic acid In methanol
Multi-step reaction with 2 steps
1: TsOH / dioxane; butan-2-one
2: aq. HIO4 / methanol
View Scheme
With sodium hydroxide; sulfuric acid In methanol; water; acetone
phthalimide
136918-14-4

phthalimide

Cortexolone
152-58-9

Cortexolone

2-(2-((8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl)isoindoline-1,3-dione

2-(2-((8R,9S,10R,13S,14S,17R)-17-hydroxy-10,13-dimethyl-3-oxo2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl)-2-oxoethyl)isoindoline-1,3-dione

Conditions
ConditionsYield
With fluorosulfonyl fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene In N,N-dimethyl-formamide at 20℃; for 0.166667h;82%
Cortexolone
152-58-9

Cortexolone

A

Progesterone
57-83-0

Progesterone

B

21-Hydroxyprogesterone
64-85-7

21-Hydroxyprogesterone

Conditions
ConditionsYield
With trimethylsilyl iodide In acetonitrile for 3h; Ambient temperature;A 5%
B 72%
With trimethylsilyl iodide In acetonitrile for 3h; Ambient temperature;A 5%
B 72%
With trimethylsilyl iodide In chloroform for 3h; Ambient temperature;A 53%
B 10%
With trimethylsilyl iodide In chloroform for 3h; Ambient temperature;A 38%
B 48%
formaldehyd
50-00-0

formaldehyd

Cortexolone
152-58-9

Cortexolone

17,20:20,21-bismethylenedioxy-4-pregnen-3-one
6173-64-4

17,20:20,21-bismethylenedioxy-4-pregnen-3-one

Conditions
ConditionsYield
With hydrogenchloride In chloroform; water at 20℃; for 5h;71%
With hydrogenchloride; chloroform
Cortexolone
152-58-9

Cortexolone

A

20-hydroxy-3-oxo-4,trans-17(20)-pregnadien-21-al
118864-86-1

20-hydroxy-3-oxo-4,trans-17(20)-pregnadien-21-al

B

20-hydroxy-3-oxo-4,cis-17(20)-pregnadien-21-al
118864-85-0

20-hydroxy-3-oxo-4,cis-17(20)-pregnadien-21-al

Conditions
ConditionsYield
With toluene-4-sulfonic acid In 1,4-dioxane Heating;A 10%
B 71%
With zinc diacetate; acetic acid Heating;A 6%
B 16.6%
With zinc diacetate; acetic acid Heating;A 6%
B 16.6%
Cortexolone
152-58-9

Cortexolone

17α,21-Dihydroxypregn-4-en-3,20-dione 21-phosphate
57099-41-9

17α,21-Dihydroxypregn-4-en-3,20-dione 21-phosphate

Conditions
ConditionsYield
With pyridine; 2-cyanoethyl phosphate; dicyclohexyl-carbodiimide70%
Cortexolone
152-58-9

Cortexolone

2,2-dimethoxy-propane
77-76-9

2,2-dimethoxy-propane

17,21-dihydroxy-3-methoxypregna-3,5-dien-20-one 17,21-acetonide
55388-55-1

17,21-dihydroxy-3-methoxypregna-3,5-dien-20-one 17,21-acetonide

Conditions
ConditionsYield
With toluene-4-sulfonic acid In N,N-dimethyl-formamide for 6h; Heating;61%
Cortexolone
152-58-9

Cortexolone

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester
21085-72-3

1-bromo-2,3,4-tri-O-acetyl-α-D-glucuronic acid methyl ester

pregn-4-en-17α,21-diol-3,20-dione-21-O-(methyl 2',3',4'-tri-O-acetyl-β-D-glucuronate)
105403-76-7

pregn-4-en-17α,21-diol-3,20-dione-21-O-(methyl 2',3',4'-tri-O-acetyl-β-D-glucuronate)

Conditions
ConditionsYield
With silver carbonate In toluene for 6h; Koenigs-Knorr synthesis; Reflux;48%
Cortexolone
152-58-9

Cortexolone

A

(8R,9S,10R,13S,14S,17R)-17-((R)-1,2-Dihydroxy-ethyl)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
128-19-8

(8R,9S,10R,13S,14S,17R)-17-((R)-1,2-Dihydroxy-ethyl)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one

B

4-pregnen-17α,20β,21-triol-3-one
3946-10-9

4-pregnen-17α,20β,21-triol-3-one

Conditions
ConditionsYield
With sodium tetrahydroborate; calcium chloride In water; ethyl acetate at -27℃;A n/a
B 40%

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View