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inquiryC6H15NO2 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL 6452-57-9 Application:C6H15NO2 3-(ISOPROPYLAMINO)-1,2-PROPANEDIOL 6452-57-9
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inquiry3-(ISOPROPYLAMINO)-1,2-PROPANEDIOLAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express
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inquiryConditions | Yield |
---|---|
In ethanol for 3h; Ambient temperature; | |
In isopropyl alcohol 1.) 70 deg C, 1.5 h, 2.) RT, 15 h; | |
at 25℃; | 53 g |
(RS)-metoprolol
A
1,2-dihydroxy-3-isopropylaminopropane
G
methyl (±)-2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetate
H
3-<4-(methylacetyl)phenoxy>-1-(isopropylamino)-2-propanol
Conditions | Yield |
---|---|
With titanium(IV) oxide; oxygen pH=4 - 7; Kinetics; Reagent/catalyst; UV-irradiation; |
(RS)-metoprolol
A
1,2-dihydroxy-3-isopropylaminopropane
F
methyl (±)-2-(4-(2-hydroxy-3-(isopropylamino)propoxy)phenyl)acetate
G
3-<4-(methylacetyl)phenoxy>-1-(isopropylamino)-2-propanol
Conditions | Yield |
---|---|
With P25; dihydrogen peroxide; oxygen pH=5 - 7; Kinetics; Reagent/catalyst; UV-irradiation; |
propranolol
A
1,2-dihydroxy-3-isopropylaminopropane
G
N-hydroxypropranolol
H
benzene-1,2-dicarboxylic acid
Conditions | Yield |
---|---|
With dihydrogen peroxide In aq. phosphate buffer at 20℃; Kinetics; Reagent/catalyst; UV-irradiation; Photolysis; |
A
1-(isopropylamino)-2-propanol
B
1,2-dihydroxy-3-isopropylaminopropane
E
alpha-methoxy-4-hydroxyacetophenone
Conditions | Yield |
---|---|
With 1at% Cu-doped TiO2 at 25℃; for 0.583333h; pH=Ca. 5.6; Reagent/catalyst; UV-irradiation; |
1,2-dihydroxy-3-isopropylaminopropane
4-(2-isopropoxy-ethoxymethyl)-phenol
Conditions | Yield |
---|---|
With diamide In dichloromethane at 25℃; Solvent; Temperature; Inert atmosphere; | 92% |
4-hydroxybenzoyl chloride
1,2-dihydroxy-3-isopropylaminopropane
4-Hydroxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; | 62% |
1,2-dihydroxy-3-isopropylaminopropane
1-benzothiazol-6-yloxy-3-isopropylamino-propan-2-ol
Conditions | Yield |
---|---|
With p-toluenesulfonic acid monohydrate In piperidine; toluene | 57% |
1,2-dihydroxy-3-isopropylaminopropane
4-hydroxymethylbenzoyl chloride
4-Hydroxymethyl-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; | 6% |
3,4-(methylenedioxy)benzoyl chloride
1,2-dihydroxy-3-isopropylaminopropane
3-(isopropylamino)-2-hydroxypropyl 3,4-(methylenedioxy)benzoate
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
4-(benzyloxy)benzoic acid chloride
1,2-dihydroxy-3-isopropylaminopropane
4-Benzyloxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
2-allyloxybenzoyl chloride
2-Allyloxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
2-propoxybenzoyl chloride
2-Propoxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
3-Aminobenzoyl chloride
3-Amino-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
3-propoxy-benzoyl chloride
3-Propoxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
3-acetylaminobenzoyl chloride
3-Acetylamino-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
3-allyloxy-benzoyl chloride
3-Allyloxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
4-fluorobenzoyl chloride
4-Fluoro-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
o-chlorobenzoyl chloride
3-(isopropylamino)-2-hydroxypropyl 2-chlorobenzoate
Conditions | Yield |
---|---|
With pyridine; pyridine hydrochloride for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
4-cyanobenzoyl chlorIde
4-Cyano-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
benzaldehyde
2-Phenyl-3-isopropyl-5-(hydroxymethyl)-oxazolidine
Conditions | Yield |
---|---|
With benzoic acid In toluene for 3h; Heating; |
1,2-dihydroxy-3-isopropylaminopropane
4-methoxy-benzoyl chloride
4-Methoxy-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
4-nitro-benzoyl chloride
4-Nitro-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
ortho-toluoyl chloride
2-Methyl-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
4-acetamidobenzoyl chloride
4-Acetylamino-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
4-aminobenzoyl chloride
4-Amino-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
3-fluorobenzoyl chloride
3-Fluoro-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
2-Fluorobenzoyl chloride
2-Fluoro-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
naphthalene-1-carbonic acid chloride
Naphthalene-1-carboxylic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
m-nitrobenzoic acid chloride
3-Nitro-benzoic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
2-naphthaloyl chloride
Naphthalene-2-carboxylic acid 2-hydroxy-3-isopropylamino-propyl ester
Conditions | Yield |
---|---|
With pyridine In toluene for 2h; Ambient temperature; |
1,2-dihydroxy-3-isopropylaminopropane
2-<4-<3-(isopropylamino)-2-hydroxypropoxy>phenyl>-4-(2-thienyl)imidazole
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: benzoic acid / toluene / 3 h / Heating 2: pyridine / 3 h / 25 °C 3: 1.) NaH / 1.) DMF, 60 deg C, 0.5 h, 2.) DMF, reflux, 16 h 4: 1 N HCl, NaOAc / 5 h / Ambient temperature View Scheme |
1,2-dihydroxy-3-isopropylaminopropane
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: benzoic acid / toluene / 3 h / Heating 2: pyridine / 3 h / 25 °C 3: 1.) NaH / 1.) DMF, 60 deg C, 0.5 h, 2.) DMF, reflux, 16 h View Scheme |
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