Products

Refine

Country

Business Type

Certificate

Display

GIHI CHEMICALS CO.,LIMITED

Product Name:Afimoxifene CAS No.: 68392-35-8 Chemical formula: C26H29NO2 Molecular weight:387.51 Item Standard Appearance white powder Identification H-NMR

Afimoxifene

Cas:68392-35-8

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 68392-35-8 with best quality

Cas:68392-35-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph

4-{1-{4-[2-(Dimethylamino)-ethoxy]-phenyl}-2-phenylbut-1-en-1-yl}-phenol

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]- 68392-35-8

Cas:68392-35-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Afimoxifene CAS:68392-35-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates

Afimoxifene CAS:68392-35-8

Cas:68392-35-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

Cas:68392-35-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. 1. best service, high quality and reasonable way for h

(E/Z)-4-Hydroxy TaMoxifen

Cas:68392-35-8

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

4-{1-{4-[2-(Dimethylamino)-ethoxy]-phenyl}-2-phenylbut-1-en-1-yl}-phenol

Cas:68392-35-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Best OfferAfimoxifene

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Afimoxifene

Cas:68392-35-8

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

NANJING SUNNY PHARMATECH CO., LTD

Our product has a very high quality and now we are exporting to customers overseas with very positive feedback. With best price, quality and service from Nanjing Sunny, we are confident to set up a very nice cooperation with customers all over the w

Afimoxifene

Cas:68392-35-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

Afimoxifene

Cas:68392-35-8

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Afimoxifene 250mg

Cas:68392-35-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals

Afimoxifene

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

1.Our services:A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.

Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

Afimoxifene

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Phenol,4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]-

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

BOC Sciences

GMP factory Packing with pallet as buyer's special request Best service after shipment with e-mail Cargos together with container sales seervice available Api, inhibitor, and fine chemicals for more than 6 years. Application:

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hubei Langyou International Trading Co., Ltd

Afimoxifene cas 68392-35-8 Application:Afimoxifene cas 68392-35-8

Afimoxifene cas 68392-35-8

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Other

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

Factory supply high purity low priceAppearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Afimoxifene CAS No.68392-35-8

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

DB BIOTECH CO., LTD

best seller Application:API

Afimoxifene

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

Afimoxifene

Cas:68392-35-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

C37H34BrNO7

C37H34BrNO7

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
With water In methanol for 0.0333333h; Quantum yield; Photolysis;73%
(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene
91221-46-4

1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Stage #1: 1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene With caesium carbonate In N,N-dimethyl-formamide for 0.5h; Reflux;
Stage #2: (2-chloroethyl)dimethylamine hydrochloride In N,N-dimethyl-formamide at 120℃; for 7h;
67%
Stage #1: 1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene With caesium carbonate In N,N-dimethyl-formamide at 70 - 80℃; for 0.166667h;
Stage #2: (2-chloroethyl)dimethylamine hydrochloride In N,N-dimethyl-formamide for 1.75h;
30%
Stage #1: 1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 0.166667h;
Stage #2: (2-chloroethyl)dimethylamine hydrochloride In N,N-dimethyl-formamide at 80℃; for 5.5h;
13.6%
Stage #1: 1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene With caesium carbonate In N,N-dimethyl-formamide at 80℃; for 0.166667h;
Stage #2: (2-chloroethyl)dimethylamine hydrochloride In N,N-dimethyl-formamide at 80℃; for 5.5h;
13.6%
dimethyl amine
124-40-3

dimethyl amine

E/Z-1-[4-(2-bromoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbutene
147323-02-2

E/Z-1-[4-(2-bromoethoxy)phenyl]-1-(4-hydroxyphenyl)-2-phenylbutene

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
In tetrahydrofuran at 60℃; for 43h;31%
1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene
91221-46-4

1,1-bis(4-hydroxyphenyl)-2-phenyl-1-butene

2-(dimethylamino)ethyl chloride
107-99-3

2-(dimethylamino)ethyl chloride

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
With caesium carbonate In N,N-dimethyl-formamide Inert atmosphere;24%
Propylbenzene
103-65-1

Propylbenzene

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium tert-butoxide; n-butyllithium; tetramethylethylenediamine / hexane; tetrahydrofuran / 0.5 h / 20 °C
1.2: 97 percent / hexane; tetrahydrofuran / 4.5 h / -78 - 20 °C
2.1: 93 percent / aq. hydrochloric acid / ethanol; CH2Cl2 / Heating
3.1: 90 percent / aq. sodium hydroxide; tetrabutylammonium hydrogen sulfate / 18 h / 20 °C
4.1: 57 percent / boron tribromide / CH2Cl2 / 4.5 h
5.1: 31 percent / tetrahydrofuran / 43 h / 60 °C
View Scheme
4-hydroxy-4'-methoxybenzophenone
61002-54-8

4-hydroxy-4'-methoxybenzophenone

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: sodium hydride / dimethylformamide / 1 h / 0 °C
1.2: 95 percent / dimethylformamide / 2 h / 20 °C
2.1: potassium tert-butoxide; n-butyllithium; tetramethylethylenediamine / hexane; tetrahydrofuran / 0.5 h / 20 °C
2.2: 97 percent / hexane; tetrahydrofuran / 4.5 h / -78 - 20 °C
3.1: 93 percent / aq. hydrochloric acid / ethanol; CH2Cl2 / Heating
4.1: 90 percent / aq. sodium hydroxide; tetrabutylammonium hydrogen sulfate / 18 h / 20 °C
5.1: 57 percent / boron tribromide / CH2Cl2 / 4.5 h
6.1: 31 percent / tetrahydrofuran / 43 h / 60 °C
View Scheme
4-(methoxymethoxy)-4'-methoxybenzophenone
115499-97-3

4-(methoxymethoxy)-4'-methoxybenzophenone

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: potassium tert-butoxide; n-butyllithium; tetramethylethylenediamine / hexane; tetrahydrofuran / 0.5 h / 20 °C
1.2: 97 percent / hexane; tetrahydrofuran / 4.5 h / -78 - 20 °C
2.1: 93 percent / aq. hydrochloric acid / ethanol; CH2Cl2 / Heating
3.1: 90 percent / aq. sodium hydroxide; tetrabutylammonium hydrogen sulfate / 18 h / 20 °C
4.1: 57 percent / boron tribromide / CH2Cl2 / 4.5 h
5.1: 31 percent / tetrahydrofuran / 43 h / 60 °C
View Scheme
E/Z-1-(4-hydroxyphenyl)-1-(4-methoxyphenyl)-2-phenylbutene
850256-19-8

E/Z-1-(4-hydroxyphenyl)-1-(4-methoxyphenyl)-2-phenylbutene

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 90 percent / aq. sodium hydroxide; tetrabutylammonium hydrogen sulfate / 18 h / 20 °C
2: 57 percent / boron tribromide / CH2Cl2 / 4.5 h
3: 31 percent / tetrahydrofuran / 43 h / 60 °C
View Scheme
1-(4-methoxymethoxyphenyl)-1-(4-methoxyphenyl)-2-phenylbutan-1-ol
671791-56-3

1-(4-methoxymethoxyphenyl)-1-(4-methoxyphenyl)-2-phenylbutan-1-ol

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 93 percent / aq. hydrochloric acid / ethanol; CH2Cl2 / Heating
2: 90 percent / aq. sodium hydroxide; tetrabutylammonium hydrogen sulfate / 18 h / 20 °C
3: 57 percent / boron tribromide / CH2Cl2 / 4.5 h
4: 31 percent / tetrahydrofuran / 43 h / 60 °C
View Scheme
E/Z-1-[4-(2-bromoethoxy)phenyl]-1-(4-methoxyphenyl)-2-phenylbut-1-ene
850256-21-2

E/Z-1-[4-(2-bromoethoxy)phenyl]-1-(4-methoxyphenyl)-2-phenylbut-1-ene

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 57 percent / boron tribromide / CH2Cl2 / 4.5 h
2: 31 percent / tetrahydrofuran / 43 h / 60 °C
View Scheme
uridine 3'-(4-hydroxytamoxifen phosphate)
1361392-98-4

uridine 3'-(4-hydroxytamoxifen phosphate)

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
With sodium chloride pH=6; Mes-NaOH buffer; Enzymatic reaction;
4,4'-Dihydroxybenzophenone
611-99-4

4,4'-Dihydroxybenzophenone

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: titanium tetrachloride; zinc / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere; Reflux; Darkness
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.17 h / 70 - 80 °C
2.2: 1.75 h
View Scheme
Multi-step reaction with 2 steps
1.1: zinc; titanium tetrachloride / tetrahydrofuran / 12 h / -20 °C / Inert atmosphere; Reflux; Darkness
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / Reflux
2.2: 7 h / 120 °C
View Scheme
Multi-step reaction with 2 steps
1.1: titanium tetrachloride; zinc / tetrahydrofuran / 2 h / -10 - 95 °C / Inert atmosphere
1.2: 2 h / 0 - 95 °C / Inert atmosphere; Darkness
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.17 h / 80 °C
2.2: 5.5 h / 80 °C
View Scheme
Multi-step reaction with 2 steps
1.1: zinc; titanium tetrachloride / tetrahydrofuran / 2 h / Inert atmosphere; Darkness
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.17 h / 80 °C
2.2: 5.5 h / 80 °C
View Scheme
Multi-step reaction with 2 steps
1: titanium tetrachloride; zinc / tetrahydrofuran / Inert atmosphere
2: caesium carbonate / N,N-dimethyl-formamide / Inert atmosphere
View Scheme
tamoxifen
10540-29-1

tamoxifen

A

N-desmethyltamoxifen

N-desmethyltamoxifen

B

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
With Vitamin C; Agrocybe aegerita peroxygenase; dihydrogen peroxide at 20℃; for 0.05h; pH=7; aq. phosphate buffer; Enzymatic reaction; regioselective reaction;
1-phenyl-propan-1-one
93-55-0

1-phenyl-propan-1-one

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: zinc; titanium tetrachloride / tetrahydrofuran / 12 h / -20 °C / Inert atmosphere; Reflux; Darkness
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.5 h / Reflux
2.2: 7 h / 120 °C
View Scheme
Multi-step reaction with 2 steps
1.1: zinc; titanium tetrachloride / tetrahydrofuran / 2 h / Inert atmosphere; Darkness
2.1: caesium carbonate / N,N-dimethyl-formamide / 0.17 h / 80 °C
2.2: 5.5 h / 80 °C
View Scheme
Multi-step reaction with 2 steps
1: titanium tetrachloride; zinc / tetrahydrofuran / Inert atmosphere
2: caesium carbonate / N,N-dimethyl-formamide / Inert atmosphere
View Scheme
C46H54N4O7

C46H54N4O7

A

C31H39N3O3

C31H39N3O3

B

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
for 0.166667h; Quantum yield; Kinetics; Photolysis;
C36H34BrNO5

C36H34BrNO5

A

C36H34BrNO5

C36H34BrNO5

B

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Claisen Rearrangement; Photolysis;
C36H34BrNO5

C36H34BrNO5

A

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

B

6-bnromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one
223420-41-5

6-bnromo-7-hydroxy-4-(hydroxymethyl)-2H-chromen-2-one

Conditions
ConditionsYield
With water In methanol Quantum yield; Photolysis;
C40H44N2O4

C40H44N2O4

A

C40H44N2O4

C40H44N2O4

B

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
Quantum yield; Claisen Rearrangement; Photolysis;
C42H44BrN3O8

C42H44BrN3O8

A

C31H39N3O3

C31H39N3O3

B

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

Conditions
ConditionsYield
With water In methanol for 0.0833333h; Quantum yield; Kinetics; Photolysis;
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

2-methacryloyloxyethyl hydrogen succinate
20882-04-6

2-methacryloyloxyethyl hydrogen succinate

C36H41NO7

C36H41NO7

Conditions
ConditionsYield
Stage #1: 2-methacryloyloxyethyl hydrogen succinate With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 0.5h;
Stage #2: 4-hydroxytamoxifen In dichloromethane for 16h;
96.02%
Stage #1: 2-methacryloyloxyethyl hydrogen succinate With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In dichloromethane at 0 - 20℃; for 0.5h;
Stage #2: 4-hydroxytamoxifen In dichloromethane for 16h;
96.02%
trifluoromethylsulfonic anhydride
358-23-6

trifluoromethylsulfonic anhydride

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

(E,Z)-4-(1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl)phenyl trifluoromethanesulfonate
1370699-80-1

(E,Z)-4-(1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl)phenyl trifluoromethanesulfonate

Conditions
ConditionsYield
With pyridine In dichloromethane at 0 - 20℃; for 1h;95%
2-(dimethylamino)ethyl chloride
107-99-3

2-(dimethylamino)ethyl chloride

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

[2-(4-{1-[4-(2-Dimethylamino-ethoxy)-phenyl]-2-phenyl-but-1-enyl}-phenoxy)-ethyl]-dimethyl-amine

[2-(4-{1-[4-(2-Dimethylamino-ethoxy)-phenyl]-2-phenyl-but-1-enyl}-phenoxy)-ethyl]-dimethyl-amine

Conditions
ConditionsYield
With sodium methylate In N,N-dimethyl-formamide; toluene for 5h; Heating;83%
N1-methyl-N1-(2-phenylcyclopropyl)ethane-1,2-diamine

N1-methyl-N1-(2-phenylcyclopropyl)ethane-1,2-diamine

4-Nitrophenyl chloroformate
7693-46-1

4-Nitrophenyl chloroformate

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenyl (2-(methyl(2-phenylcyclopropyl)amino)ethyl)carbamate

4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenyl (2-(methyl(2-phenylcyclopropyl)amino)ethyl)carbamate

Conditions
ConditionsYield
Stage #1: 4-Nitrophenyl chloroformate; 4-hydroxytamoxifen With pyridine In dichloromethane at 20℃; for 24h; Cooling with ice;
Stage #2: N1-methyl-N1-(2-phenylcyclopropyl)ethane-1,2-diamine With triethylamine In dichloromethane at 20℃; for 22h; Cooling with ice;
68.4%
pivaloyl chloride
3282-30-2

pivaloyl chloride

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

A

2,2-Dimethyl-propionic acid 4-{(Z)-1-[4-(2-dimethylamino-ethoxy)-phenyl]-2-phenyl-but-1-enyl}-phenyl ester

2,2-Dimethyl-propionic acid 4-{(Z)-1-[4-(2-dimethylamino-ethoxy)-phenyl]-2-phenyl-but-1-enyl}-phenyl ester

B

(E)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenyl pivalate

(E)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenyl pivalate

Conditions
ConditionsYield
With sodium hydroxide In chloroform for 3h; Ambient temperature; Title compound not separated from byproducts;
acetyl chloride
75-36-5

acetyl chloride

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

A

(E)-4-{1-[4-(2-dimethylaminoethoxy)phenyl]-2-phenylbut-1-enyl}phenyl acetate
76117-70-9

(E)-4-{1-[4-(2-dimethylaminoethoxy)phenyl]-2-phenylbut-1-enyl}phenyl acetate

B

C28H31NO3

C28H31NO3

Conditions
ConditionsYield
With pyridine for 1h; Friedel Crafts Acylation; Heating / reflux;
5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
144490-31-3, 118362-03-1, 131349-31-0, 131349-37-6

5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite

4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

C65H75N4O12PSi
1361390-71-7

C65H75N4O12PSi

Conditions
ConditionsYield
Stage #1: 5'-O-(4,4'-dimethoxytrityl)-2'-O-(tert-butyldimethylsilyl)uridine-3'-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite; 4-hydroxytamoxifen With N-methylbenzimidazolium triflate In acetonitrile for 2.5h; Molecular sieve;
Stage #2: With pyridine; water; iodine In tetrahydrofuran for 1h;
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

N,N-dimethyl-2-(4-(2-phenyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)but-1-en-1-yl)phenoxy)ethanamine
1370699-81-2

N,N-dimethyl-2-(4-(2-phenyl-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)but-1-en-1-yl)phenoxy)ethanamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: pyridine / dichloromethane / 1 h / 0 - 20 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 80 °C / Inert atmosphere
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

potassium [4-(1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl)phenyl]trifluoroboranuide
1371574-63-8

potassium [4-(1-{4-[2-(dimethylamino)ethoxy]phenyl}-2-phenylbut-1-en-1-yl)phenyl]trifluoroboranuide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: pyridine / dichloromethane / 1 h / 0 - 20 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 80 °C / Inert atmosphere
3: potassium hydrogen difluoride / methanol; water / 0.25 h / 20 °C
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

(4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenyl)boronic acid
1370699-82-3

(4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenyl)boronic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: pyridine / dichloromethane / 1 h / 0 - 20 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; potassium acetate / 1,4-dioxane / 80 °C / Inert atmosphere
3: potassium hydrogen difluoride / methanol; water / 0.25 h / 20 °C
4: chloro-trimethyl-silane / water; acetonitrile / 1 h / 20 °C
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

(E/Z)-4-hydroxy-N-desmethyltamoxifen hydrochloride
1197194-41-4

(E/Z)-4-hydroxy-N-desmethyltamoxifen hydrochloride

Conditions
ConditionsYield
Stage #1: 4-hydroxytamoxifen With carbonochloridic acid 1-chloro-ethyl ester; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene In dichloromethane at 0℃; for 12.5h; Reflux;
Stage #2: With hydrogenchloride In methanol; water for 3h; Reflux;
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

C43H44N4O4
1426676-56-3

C43H44N4O4

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: carbonochloridic acid 1-chloro-ethyl ester; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 12.5 h / 0 °C / Reflux
1.2: 3 h / Reflux
2.1: dichloromethane / 8 h / 20 °C
3.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
3.2: 20 °C
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

C47H52N4O6
1426676-59-6

C47H52N4O6

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: carbonochloridic acid 1-chloro-ethyl ester; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 12.5 h / 0 °C / Reflux
1.2: 3 h / Reflux
2.1: dichloromethane / 8 h / 20 °C
3.1: trifluoroacetic acid / dichloromethane / 20 °C
3.2: 20 °C
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

C45H53ClN7O4Pt(2+)*2NO3(1-)

C45H53ClN7O4Pt(2+)*2NO3(1-)

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: carbonochloridic acid 1-chloro-ethyl ester; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 12.5 h / 0 °C / Reflux
1.2: 3 h / Reflux
2.1: dichloromethane / 8 h / 20 °C
3.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C
3.2: 20 °C
4.1: silver nitrate / N,N-dimethyl-formamide
4.2: 120 h / -10 - 4 °C
4.3: 0.5 h / 20 °C
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

C49H61ClN7O6Pt(2+)*2NO3(1-)

C49H61ClN7O6Pt(2+)*2NO3(1-)

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: carbonochloridic acid 1-chloro-ethyl ester; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 12.5 h / 0 °C / Reflux
1.2: 3 h / Reflux
2.1: dichloromethane / 8 h / 20 °C
3.1: trifluoroacetic acid / dichloromethane / 20 °C
3.2: 20 °C
4.1: silver nitrate / N,N-dimethyl-formamide
4.2: -10 - 4 °C
4.3: 20 °C
View Scheme
4-hydroxytamoxifen
68392-35-8

4-hydroxytamoxifen

C48H52N4O6

C48H52N4O6

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: carbonochloridic acid 1-chloro-ethyl ester; N,N,N',N'-tetramethyl-1,8-diaminonaphthalene / dichloromethane / 12.5 h / 0 °C / Reflux
1.2: 3 h / Reflux
2.1: dichloromethane / 8 h / 20 °C
View Scheme

Hot Products

Post buying leads

About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia

Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog

©2008 LookChem.com,License: ICP

NO.:Zhejiang16009103

complaints:service@lookchem.com Desktop View