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Antimex Chemical Limied

Tamoxifen free base; Genox; Kessar; Nolvadex; Nolvadex-D; Tamoxen; (Z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethanamine; 2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamin; Leading Manufacture of "tamoxifen&quo

Tamoxifen CAS 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $15.0

Type:Lab/Research institutions

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Hubei Vanz Pharm Co.,Ltd

Hubei Vanz Pharm Co.,Ltd Manufacturer Supply Top Quality CAS 148553-50-8 pregabalin powder. Pregabalin, is a medication used to treat epilepsy, neuropathic pain, fibromyalgia, and generalized anxiety disorder. Its use for epilepsy is as an add-on th

Tamoxifen UPS CAS10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $400.0

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Kono Chem Co.,Ltd

Product Name: Factory supply Nolvadex/Tamoxifen CAS 10540-29-1 Purity: 99% CAS: 10540-29-1 Molar mass: 371.515 g/mol Density: 1.042 g/cm3 Melting point: 97-98 Flash point: 140 Appearance: Wh

CAS:10540-29-1 Tamoxifen

Cas:10540-29-1

Min.Order:1 Kilogram

Negotiable

Type:Other

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Henan Allgreen Chemical Co.,Ltd

The company has a professional R & D team, mature technology, very competitive prices and stable high quality products for customers to order high quality and low price product efforts! Appearance:White or off-white Solid Storage:Sealed, dr

Tamoxifen

Cas:10540-29-1

Min.Order:1 Kilogram

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Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Tamoxifen

Cas:10540-29-1

Min.Order:1

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Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality tamoxifen

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Tamoxifen

Cas:10540-29-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Tamoxifen CAS 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Tamoxifen Basic information Antiestrogen drug Origin of the study Application Pharmacokinetics Adverse reactions ContraindicationsPrecautions Drug interactions Product Name: Tamoxifen

Tamoxifen10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:White powder Storage:R.T Package:25kg/drum Application:anti-estrogen drugs Transportation:Express/Sea/Air Port:Any port in China

Tamoxifen cas 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

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Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:white powder Storage:Store in sealed containers at cool & dr

Powder Nolvadex Tamoxifen Citrate Anti Estrogen Steroids CAS 10540-29-1

Cas:10540-29-1

Min.Order:100 Gram

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Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Ethanamine,2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl- 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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HANWAYS CHEMPHARM CO.,LIMITED

1, High quality with competitive price: 1)Standard: Enterprise Standard 2)All Purity min 99% 3)We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1)Parcel can be sent out in 24 hours after paymen

High quality with Good Price Tamoxifen CAS 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

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Type:Trading Company

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

API Powder Tamoxifen CAS:10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $486.0 / 500.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, steroids, pharmaceutic

Tamoxifen

Cas:10540-29-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Shanghai Terui OP New Material Technology Co., Ltd.

We generally use secure shipping methods that do not require you to do any customs clearance. Free shipping to your address without worrying about any customs issues. We have a professional customs clearance team to 100% guarantee the safe delivery o

2022Best Price CAS 10540-29-1 Tamoxifen

Cas:10540-29-1

Min.Order:1 Kilogram

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Type:Trading Company

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Ethanamine,2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

Cas:10540-29-1

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Minimum Order Qty. 10 Gram Supply Ability 500 Kilograms/Month Storage store in cool, dry, ventilated place 20℃ Delivery Time 3 business days after payment Payment Term TT,western union,Paypal,MoneyGram Package 10g,20g,50g,100g,500g,1KGS,

Tamoxifen CAS NO.10540-29-1

Cas:10540-29-1

Min.Order:10 Gram

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Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Ethanamine,2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

Cas:10540-29-1

Min.Order:0

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Type:Lab/Research institutions

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Shanghai Send Pharmaceutical Technology Co., Ltd.

low price high quality high purity good sevice stock Appearance:white Storage:Preserve In Well-Closed, Light-Resistant and Tight Containers. Store In Cool & Dry Place Package:1g,5g,10g...1kg,5kg...more Application:Active Pharmaceutical Ingr

Tamoxifen

Cas:10540-29-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

tamoxifen 10540-29-1

Cas:10540-29-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Hefei Zhaobo Technology Co., Ltd.

Tamoxifen CAS 10540-29-1 Purity: 99% Min Application: Intermediates Appearance: Powder Package: Bag Delivery: 3-5days Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system

Tamoxifen CAS 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $10.0 / 50.0

Type:Trading Company

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethanamine,2-[4-[(1Z)-1,2-diphenyl-1-buten-1-yl]phenoxy]-N,N-dimethyl-

Cas:10540-29-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Saiwante (shanghai) New Material Technology Co., Ltd.

High quality with Good Price Tamoxifen CAS 10540-29-1 roduct name Tamoxifen Synonyms tamoxifen free base; Genox; Kessar; Nolvadex; Nolvadex-D; Tamoxen; (Z)-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-

High quality with Good Price Tamoxifen CAS 10540-29-1

Cas:10540-29-1

Min.Order:1 Kilogram

FOB Price: $8.0 / 11.0

Type:Trading Company

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Shaanxi New nine Material Technology Co., Ltd.

Our Advantage & Service 1.Top quality: Using high quality material and establishing a strict quality control system,assigning specific persons in charge of each part of production,from raw material purchase to assembly. 2 Professional R&D

Tamoxifen CAS 10540-29-1 CAS NO.10540-29-1

Cas:10540-29-1

Min.Order:10 Gram

FOB Price: $8.0 / 10.0

Type:Trading Company

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Tamoxiphen

Cas:10540-29-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Hangzhou Lingrui Chemical Co.,Ltd.

Tamoxifen Steroid hormone raw materialsAppearance:White powder Storage:Placed in a cool place Package:according to customers' requirements Application:Antitumor drugs raw material, suitable for breast cancer.It is not correct that Nolvadex reduces le

Tamoxifen Steroid hormone raw materials

Cas:10540-29-1

Min.Order:1 Gram

Negotiable

Type:Other

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

Tamoxifen

Cas:10540-29-1

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Synthetic route

(Z)-1-<4-(2-chloroethoxy)phenyl>-1,2-diphenyl-1-butene
97818-83-2

(Z)-1-<4-(2-chloroethoxy)phenyl>-1,2-diphenyl-1-butene

dimethyl amine
124-40-3

dimethyl amine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 65℃; for 12h; Inert atmosphere;99%
In ethanol at 80℃; for 16h;93%
In ethanol at 75℃; for 72h;85 mg
2-(N,N-dimethylamino)ethanol
108-01-0

2-(N,N-dimethylamino)ethanol

(Z)-(1-(4-iodophenyl)but-1-ene-1,2-diyl)dibenzene

(Z)-(1-(4-iodophenyl)but-1-ene-1,2-diyl)dibenzene

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With copper(l) iodide; potassium carbonate at 110℃; for 53h; Inert atmosphere;96%
1-phenyl-1-(p-hydroxyphenyl)-2-phenylbut-1-ene
69967-80-2

1-phenyl-1-(p-hydroxyphenyl)-2-phenylbut-1-ene

(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With potassium carbonate In ethanol; toluene at 80 - 85℃; for 3h; Inert atmosphere;93%
With sodium ethanolate In ethanol for 24h; Heating;60%
With sodium hydride 1.) DMF, 2.) 50 deg C; Yield given. Multistep reaction;
iodobenzene
591-50-4

iodobenzene

(E)-N,N-dimethyl-2-(4-(1-phenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-1-en-1-yl)phenoxy)ethanamine
1421712-14-2

(E)-N,N-dimethyl-2-(4-(1-phenyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)but-1-en-1-yl)phenoxy)ethanamine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With tri-tert-butyl phosphine; potassium hydroxide; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran; water at 60℃; for 24h; Suzuki-Miyaura Coupling; regioselective reaction;93%
(Z)-N-((8-cyano-7-hydroxyquinolin-2-yl)methyl)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-aminium methanesulfonate

(Z)-N-((8-cyano-7-hydroxyquinolin-2-yl)methyl)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-aminium methanesulfonate

A

tamoxifen
10540-29-1

tamoxifen

B

C11H7N2O2(1-)

C11H7N2O2(1-)

Conditions
ConditionsYield
In ethanol pH=7.2; UV-irradiation;A 91%
B n/a
(Z)-2-(4-(1,2-diphenylbuta-1,3-dien-1-yl)phenoxy)-N,N-dimethylethanamine
604010-60-8

(Z)-2-(4-(1,2-diphenylbuta-1,3-dien-1-yl)phenoxy)-N,N-dimethylethanamine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate for 2h; atmospheric pressure;85%
With hydrogen; palladium on activated charcoal
2-(4-(1,2-diphenylbuta-1,3-dien-1-yl)phenoxy)-N,N-dimethylethanamine

2-(4-(1,2-diphenylbuta-1,3-dien-1-yl)phenoxy)-N,N-dimethylethanamine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With palladium on activated charcoal; hydrogen In ethyl acetate at 22℃; for 2h;85%
(E)-1,2-diphenyl-1-butene boronic acid
918793-63-2

(E)-1,2-diphenyl-1-butene boronic acid

[2-(4-iodophenoxy)ethyl]dimethylamine
93790-54-6

[2-(4-iodophenoxy)ethyl]dimethylamine

A

1,2-diphenyl-butan-1-one
16282-16-9

1,2-diphenyl-butan-1-one

B

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water for 18h; Suzuki-Miyaura cross-coupling; Heating;A n/a
B 73%
(Z)-1-iodo-1,2-diphenyl-1-butene
113619-15-1

(Z)-1-iodo-1,2-diphenyl-1-butene

(4-(2-(dimethylamino)ethoxy)phenyl)boronic acid
194594-60-0

(4-(2-(dimethylamino)ethoxy)phenyl)boronic acid

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water Suzuki-Miyaura cross-coupling; Heating;73%
(E)-1-(4-dimethylaminoethoxyphenyl)-1,2-diphenyl-2-(4-tolyl)thioethene
1148025-82-4

(E)-1-(4-dimethylaminoethoxyphenyl)-1,2-diphenyl-2-(4-tolyl)thioethene

ethylmagnesium chloride
2386-64-3

ethylmagnesium chloride

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With Ni(1,2-bis(diphenylphosphino)ethane)Cl2 In diethyl ether for 15h; Inert atmosphere; Reflux;73%
trans-(E)-1-bromo-2-<4-<2-(dimethylamino)ethoxy>phenyl>-1,2-diphenylethene
19118-19-5

trans-(E)-1-bromo-2-<4-<2-(dimethylamino)ethoxy>phenyl>-1,2-diphenylethene

ethyllithium
811-49-4

ethyllithium

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
In tetrahydrofuran; diethyl ether at -78 - 20℃; for 6h;72%
(E)-1-(4',4',5',5'-tetramethyl-1',3',2'-dioxaborolan-2'-yl)-1,2-diphenyl-1-butene
865999-25-3

(E)-1-(4',4',5',5'-tetramethyl-1',3',2'-dioxaborolan-2'-yl)-1,2-diphenyl-1-butene

[2-(4-iodophenoxy)ethyl]dimethylamine
93790-54-6

[2-(4-iodophenoxy)ethyl]dimethylamine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With sodium hydroxide; tri-tert-butyl phosphine; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran; hexane at 60℃; for 48h;70%
With sodium hydroxide; bis(tri-t-butylphosphine)palladium(0) In tetrahydrofuran at 60℃; for 24h;59%
(E)-1,2-diphenyl-1-butene boronic acid
918793-63-2

(E)-1,2-diphenyl-1-butene boronic acid

[2-(4-bromophenoxy)ethyl]dimethylamine
2474-07-9

[2-(4-bromophenoxy)ethyl]dimethylamine

A

1,2-diphenyl-butan-1-one
16282-16-9

1,2-diphenyl-butan-1-one

B

tamoxifen
10540-29-1

tamoxifen

C

(E)-tamoxifen
13002-65-8

(E)-tamoxifen

Conditions
ConditionsYield
With sodium carbonate; tetrakis(triphenylphosphine) palladium(0) In 1,2-dimethoxyethane; water Suzuki-Miyaura cross-coupling; Heating;A n/a
B 65%
C n/a
2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

2-(1,2-diphenylbut-1-en-1-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

[2-(4-iodophenoxy)ethyl]dimethylamine
93790-54-6

[2-(4-iodophenoxy)ethyl]dimethylamine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With bis(tri-t-butylphosphine)palladium(0); sodium hydroxide In tetrahydrofuran at 60℃; for 24h; Schlenk technique; Inert atmosphere; stereoselective reaction;65%
[2-(4-bromophenoxy)ethyl]dimethylamine
2474-07-9

[2-(4-bromophenoxy)ethyl]dimethylamine

(E)-but-1-ene-1,2-diyldibenzene
20218-41-1

(E)-but-1-ene-1,2-diyldibenzene

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
Stage #1: (E)-but-1-ene-1,2-diyldibenzene With palladium diacetate; sodium carbonate; triphenylphosphine In 1,2-dimethoxyethane at 25℃; for 0.166667h; Heck Reaction;
Stage #2: [2-(4-bromophenoxy)ethyl]dimethylamine In 1,2-dimethoxyethane for 5h; Heck Reaction; Reflux;
65%
(Z)-1,2-diphenylbut-1-en-1-yl dimethylcarbamate

(Z)-1,2-diphenylbut-1-en-1-yl dimethylcarbamate

(4-(2-(dimethylamino)ethoxy)phenyl)magnesium bromide
35258-27-6

(4-(2-(dimethylamino)ethoxy)phenyl)magnesium bromide

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With N,N'-bis(2,4,6-trimethylphenyl)imidazol-2-ylidene hydrochloride; palladium diacetate In tetrahydrofuran at 50℃; for 24h; Schlenk technique; Inert atmosphere; Sealed tube; stereoselective reaction;62%
[2-(4-iodophenoxy)ethyl]dimethylamine
93790-54-6

[2-(4-iodophenoxy)ethyl]dimethylamine

1-trimethylstannyl-1,2-diphenylbutene

1-trimethylstannyl-1,2-diphenylbutene

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With 1-methyl-pyrrolidin-2-one; tris-(dibenzylideneacetone)dipalladium(0); copper(l) iodide; triphenyl-arsane; lithium chloride at 45℃; for 48h;52%
(E)-tamoxifen
13002-65-8

(E)-tamoxifen

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With trifluorormethanesulfonic acid In dichloromethane at 0℃; for 3h;51%
With trifluorormethanesulfonic acid In dichloromethane at 0℃; for 3h;51%
With pyridine; bromine In diethyl ether; dichloromethane for 2h; Ambient temperature; Irradiation; Yield given;
2-(dimethylamino)ethyl chloride
107-99-3

2-(dimethylamino)ethyl chloride

A

tamoxifen
10540-29-1

tamoxifen

B

(E)-tamoxifen
13002-65-8

(E)-tamoxifen

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 50℃; for 0.5h;A 51%
B 44%
With sodium hydride In N,N-dimethyl-formamide at 50℃; for 0.5h;
4-(4-[2-dimethylaminoethoxy]phenyl)-3,4-diphenylbut-1-ene

4-(4-[2-dimethylaminoethoxy]phenyl)-3,4-diphenylbut-1-ene

A

tamoxifen
10540-29-1

tamoxifen

B

(E)-tamoxifen
13002-65-8

(E)-tamoxifen

Conditions
ConditionsYield
With potassium tert-butylate In dimethyl sulfoxide at 20℃; for 1h;A 39%
B 37%
(1-phenylpropyl)phosphonic acid di-o-tolyl ester
872254-52-9

(1-phenylpropyl)phosphonic acid di-o-tolyl ester

(4-(2-(dimethylamino)ethoxy)phenyl)(phenyl)methanone
51777-15-2

(4-(2-(dimethylamino)ethoxy)phenyl)(phenyl)methanone

A

tamoxifen
10540-29-1

tamoxifen

B

(E)-tamoxifen
13002-65-8

(E)-tamoxifen

Conditions
ConditionsYield
Stage #1: (1-phenylpropyl)phosphonic acid di-o-tolyl ester With n-butyllithium In tetrahydrofuran; hexane at -78℃; for 1h;
Stage #2: (4-(2-(dimethylamino)ethoxy)phenyl)(phenyl)methanone In tetrahydrofuran; hexane at -78℃; for 48h; Horner reaction;
A 28%
B 12%
carbon dioxide
124-38-9

carbon dioxide

{2-[4-((Z)-1,2-Diphenyl-but-1-enyl)-phenoxy]-ethyl}-methyl-trimethylsilanyl-amine

{2-[4-((Z)-1,2-Diphenyl-but-1-enyl)-phenoxy]-ethyl}-methyl-trimethylsilanyl-amine

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With lithium aluminium tetrahydride 1.) THF, -45 deg C - 60 deg C, 2.) 60 deg C, 10 min; Yield given. Multistep reaction;
ICI 77949
69967-79-9

ICI 77949

(2-chloroethyl)dimethylamine hydrochloride
4584-46-7

(2-chloroethyl)dimethylamine hydrochloride

A

tamoxifen
10540-29-1

tamoxifen

B

(E)-tamoxifen
13002-65-8

(E)-tamoxifen

Conditions
ConditionsYield
With sodium methylate; hydrogen cation Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
(1S,2R)-1-[4-(2-Dimethylamino-ethoxy)-phenyl]-1,2-diphenyl-butan-1-ol
748-97-0, 77542-06-4, 77542-07-5, 81992-83-8, 111914-74-0

(1S,2R)-1-[4-(2-Dimethylamino-ethoxy)-phenyl]-1,2-diphenyl-butan-1-ol

A

tamoxifen
10540-29-1

tamoxifen

B

(E)-tamoxifen
13002-65-8

(E)-tamoxifen

Conditions
ConditionsYield
With hydrogenchloride In ethanol for 0.333333h; Heating; Yield given;
trans-4-Bromotamoxifen
116057-69-3

trans-4-Bromotamoxifen

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With water; tert.-butyl lithium 1) THF, -75 deg C; Multistep reaction;
1-(4-(2-(dimethylamino)ethoxy)phenyl)-1,2-diphenylbutan-1-ol
748-97-0

1-(4-(2-(dimethylamino)ethoxy)phenyl)-1,2-diphenylbutan-1-ol

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With sulfuric acid at 50℃; for 16h; Yield given;
(Z)-1-iodo-1,2-diphenyl-1-butene
113619-15-1

(Z)-1-iodo-1,2-diphenyl-1-butene

C10H14BrNOZn

C10H14BrNOZn

tamoxifen
10540-29-1

tamoxifen

Conditions
ConditionsYield
With triphenylphosphine; bis(dibenzylideneacetone)-palladium(0) In tetrahydrofuran at 55℃; for 10h; Yield given;
ethyl bromide
74-96-4

ethyl bromide

tamoxifen
10540-29-1

tamoxifen

Tamoxifen ethyl bromide

Tamoxifen ethyl bromide

Conditions
ConditionsYield
at 20℃; for 5h;99.1%
In acetone Heating;
tamoxifen
10540-29-1

tamoxifen

[14C]-Tamoxifen N-oxide
75504-34-6

[14C]-Tamoxifen N-oxide

Conditions
ConditionsYield
With dihydrogen peroxide In methanol; water at 20℃; for 10h; Darkness;97%
With 3-chloro-benzenecarboperoxoic acid In dichloromethane at 0℃; for 1h;79%
With dihydrogen peroxide In methanol at 50 - 60℃; for 3h;43%
With dihydrogen peroxide In methanol at 20℃; for 48h;
In aq. phosphate buffer at 25℃; pH=7.4; Kinetics; Catalytic behavior; Concentration; Electrochemical reaction;
tamoxifen
10540-29-1

tamoxifen

(Z)-N-desmethyltamoxifen hydrochloride

(Z)-N-desmethyltamoxifen hydrochloride

Conditions
ConditionsYield
Stage #1: tamoxifen With carbonochloridic acid 1-chloro-ethyl ester In dichloromethane at 0 - 50℃; for 24h;
Stage #2: With methanol In toluene at 70℃; for 3h;
95%
With carbonochloridic acid 1-chloro-ethyl ester In dichloromethane at 0℃; Inert atmosphere; Reflux;91%
Stage #1: tamoxifen With carbonochloridic acid 1-chloro-ethyl ester In toluene at 0℃; for 0.25h;
Stage #2: In toluene for 19h; Reflux;
50%
With Vinyl chloroformate
tamoxifen
10540-29-1

tamoxifen

methyl iodide
74-88-4

methyl iodide

Tamoxifen methiodide
107256-99-5

Tamoxifen methiodide

Conditions
ConditionsYield
at 0℃; for 0.166667h;94.9%
In acetone at 50℃; for 48h; Inert atmosphere;87%
1-bromo-butane
109-65-9

1-bromo-butane

tamoxifen
10540-29-1

tamoxifen

Tamoxifen butyl bromide

Tamoxifen butyl bromide

Conditions
ConditionsYield
at 20℃; for 5h;94.8%
In acetone Heating;
tamoxifen
10540-29-1

tamoxifen

N-demethyltamoxifen
31750-47-7, 31750-48-8

N-demethyltamoxifen

Conditions
ConditionsYield
With carbonochloridic acid 1-chloro-ethyl ester In 1,2-dichloro-ethane for 27.15h; Reflux;91%
Stage #1: tamoxifen With 2-Chloroethyl chloroformate In 1,2-dichloro-ethane at 0℃; for 24h; Reflux;
Stage #2: In methanol for 3h; Reflux;
91%
With carbonochloridic acid 1-chloro-ethyl ester In 1,2-dichloro-ethane at 0 - 70℃;91%
tamoxifen
10540-29-1

tamoxifen

propyl bromide
106-94-5

propyl bromide

Br(1-)*C29H36NO(1+)
1245538-92-4

Br(1-)*C29H36NO(1+)

Conditions
ConditionsYield
at 20℃; for 5h;90.1%
tamoxifen
10540-29-1

tamoxifen

(8-cyano-7-hydroxyquinolin-2-yl)methyl methanesulfonate

(8-cyano-7-hydroxyquinolin-2-yl)methyl methanesulfonate

(Z)-N-((8-cyano-7-hydroxyquinolin-2-yl)methyl)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-aminium methanesulfonate

(Z)-N-((8-cyano-7-hydroxyquinolin-2-yl)methyl)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethan-1-aminium methanesulfonate

Conditions
ConditionsYield
In acetonitrile for 5h; Reflux;70%
6-bromohexanoic acid
4224-70-8

6-bromohexanoic acid

tamoxifen
10540-29-1

tamoxifen

(Z)-6-((2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl)dimethylammonio)hexanoic acid

(Z)-6-((2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)ethyl)dimethylammonio)hexanoic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 77℃; for 72h;70%
tamoxifen
10540-29-1

tamoxifen

2-(chloromethyl)-7-hydroxyquinoline-8-carbonitrile

2-(chloromethyl)-7-hydroxyquinoline-8-carbonitrile

(Z)-N-((8-cyano-7-hydroxyquinolin-2-yl)methyl)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethanaminium chloride

(Z)-N-((8-cyano-7-hydroxyquinolin-2-yl)methyl)-2-(4-(1,2-diphenylbut-1-en-1-yl)phenoxy)-N,N-dimethylethanaminium chloride

Conditions
ConditionsYield
In acetonitrile for 5h; Reflux;65%

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