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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

Benzoicacid, 3-(cyanomethyl)-, methyl ester Manufacturer/High quality/Best price/In stock

Cas:68432-92-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Cyanomethyl-benzoic acid methyl ester

Cas:68432-92-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

high quality 3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 68432-92-8 with competitive price

Cas:68432-92-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: methyl 3-(cyanomethyl)benzoate Formula: C10H9NO2 M.W.: 175.184 CAS No.: 68432-92-8 Appearance:Colorless transpare liquid Storage:Preserve in well-closed, light-resistant and airtight containers. Package:25kg/drum Application:intermediate of

methyl 3-(cyanomethyl)benzoate

Cas:68432-92-8

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Benzoicacid, 3-(cyanomethyl)-, methyl ester 68432-92-8

Cas:68432-92-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Qingdao Beluga Import and Export Co., LTD

3-CYANOMETHYLBENZOIC ACID METHYL ESTER CAS:68432-92-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high q

3-CYANOMETHYLBENZOIC ACID METHYL ESTER CAS:68432-92-8

Cas:68432-92-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail bes

99% Methyl 3-(cyanoMethyl)benzoate CAS:68432-92-8

Cas:68432-92-8

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Benzoicacid, 3-(cyanomethyl)-, methyl ester

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzoicacid, 3-(cyanomethyl)-, methyl ester

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

methyl3-(cyanomethyl)benzoate CAS NO.68432-92-8

Cas:68432-92-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: Methyl 3-(Cyanomethyl)Benzoate CAS No.: 68432-92-8 Molecule Formula:C10H9NO2 Molecule Weight:175.18 Purity: 95.0% Package: 200kg/drum Description:Colorless transparent liquid Manufacture Standards:Enterprise Standard

Lower Price Methyl 3-(Cyanomethyl)Benzoate in stock

Cas:68432-92-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Shanghai Minstar Chemical Co., Ltd

Product Name: 3-CYANOMETHYLBENZOIC ACID METHYL ESTER Synonyms: 3-CYANOMETHYLBENZOIC ACID METHYL ESTER;METHYL 3-(CYANOMETHYL) BENZOATE;Methyl m-(cyanomethyl)benzoate;Benzoicacid, 3-(cyanomethyl)-, methyl ester CAS: 68432-92-8 MF: C10H9NO2

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

Methyl 3-(cyanoMethyl)benzoate CAS:68432-92-8 CAS NO.68432-92-8

Cas:68432-92-8

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Methyl 3-(cyanomethyl)benzoate

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Suzhou Health Chemicals Co., Ltd.

High quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use

3-Cyanomethylbenzoic acid methyl ester

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

Methyl (3-cyanomethyl)benzoate cas no. 68432-92-8 98%

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

Methyl 3-(cyanoMethyl)benzoate

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

3-(Cyanomethyl)benzoic acid methyl ester

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec Methyl 3-(cyanomethyl)benzoate 100g

Cas:68432-92-8

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice.pls contact with us freely for getting detailed product spec

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Guangdong Juda Chemical Industrial Co.,Limited

Appearance:solid or liquid Storage:sealed in cool and dry place Package:As customer's requested Application:Pharma Intermediate Transportation:by courier/air/sea Port:Any port in China

Methyl 3-(cyanomethyl)benzoate CAS No.68432-92-8

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Trading Company

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DB BIOTECH CO., LTD

best seller Application:API

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

BOC Sciences

We are committed to providing our customers with the best products and services at the most competitive prices.Appearance:white crystalline powder Storage:Room temperature with sealed well Package:according to the clients requirement Application:Use

Methyl (3-cyanomethyl)benzoate

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Fandachem Co.,Ltd

Benzoicacid, 3-(cyanomethyl)-, methyl ester cas 68432-92-8Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

Benzoicacid, 3-(cyanomethyl)-, methyl ester cas 68432-92-8

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Other

inquiry

Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

3-CYANOMETHYLBENZOIC ACID METHYL ESTER

Cas:68432-92-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

trimethylsilyl cyanide
7677-24-9

trimethylsilyl cyanide

3-methoxycarbonylbenzyl bromide
1129-28-8

3-methoxycarbonylbenzyl bromide

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
With potassium carbonate In acetonitrile at 60℃; for 15h;98%
With tetrabutyl ammonium fluoride In acetonitrile for 20h; Heating / reflux;43%
potassium cyanide
151-50-8

potassium cyanide

3-methoxycarbonylbenzyl bromide
1129-28-8

3-methoxycarbonylbenzyl bromide

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
With 18-crown-6 ether In acetonitrile for 24h; Heating / reflux;96%
With 18-crown-6 ether In acetonitrile for 24h; Ambient temperature;92%
With 18-crown-6 ether In acetonitrile at 20℃; for 40h;91%
In ethanol at 60℃;68%
3-methoxycarbonylbenzyl bromide
1129-28-8

3-methoxycarbonylbenzyl bromide

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
In acetonitrile91%
In dimethyl sulfoxide
In N,N-dimethyl-formamide
potassium cyanide

potassium cyanide

3-methoxycarbonylbenzyl bromide
1129-28-8

3-methoxycarbonylbenzyl bromide

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
With 18-crown-6 ether In acetonitrile at 20℃; for 72h;91%
With 18-crown-6 ether In acetonitrile at 20℃; for 72h;91%
In methanol; water for 5h; Reflux; Inert atmosphere;1 g
sodium cyanide
773837-37-9

sodium cyanide

3-methoxycarbonylbenzyl bromide
1129-28-8

3-methoxycarbonylbenzyl bromide

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃;89%
In N,N-dimethyl-formamide at 20℃;89%
In water; N,N-dimethyl-formamide at 75℃; for 5h; Inert atmosphere;85%
sodium cyanide
143-33-9

sodium cyanide

3-methoxycarbonylbenzyl bromide
1129-28-8

3-methoxycarbonylbenzyl bromide

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
In water; N,N-dimethyl-formamide at 75℃; for 5h;70%
In water; N,N-dimethyl-formamide at 75℃; for 5h;70%
Stage #1: sodium cyanide; 3-methoxycarbonylbenzyl bromide In water; N,N-dimethyl-formamide at 75℃; for 5h;
Stage #2: With water In N,N-dimethyl-formamide
70%
4-isoxazoleboronic acid pinacol ester
928664-98-6

4-isoxazoleboronic acid pinacol ester

methyl 3-bromobenzoate
618-89-3

methyl 3-bromobenzoate

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
With potassium fluoride; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 In dimethyl sulfoxide at 130℃; for 18h; Suzuki Coupling; Inert atmosphere; Sealed tube;69%
3-azido-2-methylbut-3-en-2-ol
1624363-23-0

3-azido-2-methylbut-3-en-2-ol

3-(methoxycarbonyl)benzenediazonium tetrafluoroborate

3-(methoxycarbonyl)benzenediazonium tetrafluoroborate

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
With 2,6-dimethylpyridine In acetonitrile at 20℃; for 4h;65%
3-bromomethylbenzoyl chloride
54267-06-0

3-bromomethylbenzoyl chloride

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 91 percent / 18-crown-6 / acetonitrile / 40 h / 20 °C
View Scheme
3-Methylbenzoyl chloride
1711-06-4

3-Methylbenzoyl chloride

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: Br2 / 0.5 h / 180 °C
2: 91 percent / 18-crown-6 / acetonitrile / 40 h / 20 °C
View Scheme
1-methoxycarbonyl-3-methylbenzene
99-36-5

1-methoxycarbonyl-3-methylbenzene

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: NBS / CCl4
2: dimethylsulfoxide
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / 3 h / Inert atmosphere; Reflux; Irradiation
2: methanol; water / 5 h / Inert atmosphere; Reflux
View Scheme
Multi-step reaction with 2 steps
1: dibenzoyl peroxide; N-Bromosuccinimide / tetrachloromethane / 4 h / 70 °C
2: dimethyl sulfoxide / 3.25 h / 0 - 10 °C
View Scheme
Multi-step reaction with 2 steps
1: N-Bromosuccinimide; dibenzoyl peroxide / tetrachloromethane / Inert atmosphere; Reflux
2: tetra-(n-butyl)ammonium iodide / acetonitrile / Inert atmosphere; Reflux
View Scheme
Methyl-3-bromomethylenebenzoate

Methyl-3-bromomethylenebenzoate

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
In methanol; dichloromethane; water; acetonitrile
methyl 3-bromobenzoate
618-89-3

methyl 3-bromobenzoate

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: magnesium; iodine / tetrahydrofuran / 2 h / 70 °C / Inert atmosphere
1.2: 6 h / 0 - 20 °C / Inert atmosphere
2.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide; sodium hypochlorite; sodium hydrogencarbonate / acetonitrile / 2 h / 0.5 °C / pH 9-10
3.1: ammonia; thionyl chloride / 70 °C
4.1: thionyl chloride / chloroform / 8 h / Reflux
View Scheme
methyl 3-(2-amino-2-oxoethyl)benzoate
929301-93-9

methyl 3-(2-amino-2-oxoethyl)benzoate

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
With thionyl chloride In chloroform for 8h; Reflux;32 g
m-bromobenzoic acid
585-76-2

m-bromobenzoic acid

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: thionyl chloride / 5 h / 70 °C
1.2: 4 h / 20 °C / Cooling with ice
2.1: magnesium; iodine / tetrahydrofuran / 2 h / 70 °C / Inert atmosphere
2.2: 6 h / 0 - 20 °C / Inert atmosphere
3.1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide; sodium hypochlorite; sodium hydrogencarbonate / acetonitrile / 2 h / 0.5 °C / pH 9-10
4.1: ammonia; thionyl chloride / 70 °C
5.1: thionyl chloride / chloroform / 8 h / Reflux
View Scheme
methyl 3-(2-hydroxylethyl)benzoate
153599-45-2

methyl 3-(2-hydroxylethyl)benzoate

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium bromide; sodium hypochlorite; sodium hydrogencarbonate / acetonitrile / 2 h / 0.5 °C / pH 9-10
2: ammonia; thionyl chloride / 70 °C
3: thionyl chloride / chloroform / 8 h / Reflux
View Scheme
m-Toluic acid
99-04-7

m-Toluic acid

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: thionyl chloride / 4 h / Reflux
1.2: 100 °C
2.1: 40 °C
3.1: methanol / 2 h / 40 - 80 °C
View Scheme
sodium cyanide
773837-37-9

sodium cyanide

1-methoxycarbonyl-3-methylbenzene
99-36-5

1-methoxycarbonyl-3-methylbenzene

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

Conditions
ConditionsYield
In methanol at 40 - 80℃; for 2h;
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

methyl 3-(2-amino-2-thioxoethyl)benzoate

methyl 3-(2-amino-2-thioxoethyl)benzoate

Conditions
ConditionsYield
With sodium hydrogen sulfide; hydrogen sulfide; acetamidine hydrochloride In water at 70℃; under 3750.38 Torr; for 4h; pH=10; Reagent/catalyst; pH-value; Pressure; Temperature; Autoclave;98.6%
With sodium hydrogen sulfide; triethylamine hydrochloride In methanol at 70℃; for 7h; Concentration; Reagent/catalyst;95.8%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

2-(3-(hydroxymethyl)phenyl)acetonitrile
177665-49-5

2-(3-(hydroxymethyl)phenyl)acetonitrile

Conditions
ConditionsYield
With sodium tetrahydroborate In tetrahydrofuran; methanol at 0 - 10℃; for 16.25h;95%
With lithium borohydride In tetrahydrofuran for 4h; Heating / reflux;41%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

carbonic acid dimethyl ester
616-38-6

carbonic acid dimethyl ester

2-<3-(carboxymethyl)phenyl>propionitrile
146257-39-8

2-<3-(carboxymethyl)phenyl>propionitrile

Conditions
ConditionsYield
With potassium carbonate at 180℃; for 8h; Product distribution; Mechanism; the course of reaction according various periods of time;91%
With potassium carbonate at 180℃; for 8h;91%
With potassium carbonate at 180℃; for 8h;91%
methanol
67-56-1

methanol

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

3-methoxycarbonylphenylacetic acid methyl ester
52787-20-9

3-methoxycarbonylphenylacetic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride In methanol at 20℃; for 6h;87%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

(3-(2-aminoethyl)phenyl)methanol
743384-09-0

(3-(2-aminoethyl)phenyl)methanol

Conditions
ConditionsYield
With aluminum (III) chloride; lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at 20℃; Inert atmosphere;83%
Stage #1: methyl 3-cyanomethylbenzoate With aluminum (III) chloride; lithium aluminium tetrahydride In tetrahydrofuran; diethyl ether at 20℃; Inert atmosphere;
Stage #2: With sulfuric acid; water In tetrahydrofuran; diethyl ether
Multi-step reaction with 2 steps
1: sodium tetrahydroborate / tetrahydrofuran; methanol / 16.25 h / 0 - 10 °C
2: hydrogen; ammonia / Raney-Ni / methanol / 3 h / 10 °C
View Scheme
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

3-(cyanomethyl)benzoic acid
5689-33-8

3-(cyanomethyl)benzoic acid

Conditions
ConditionsYield
With lithium hydroxide; water In tetrahydrofuran at 20 - 50℃;79%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

methyl iodide
74-88-4

methyl iodide

methyl 3-(1-cyano-1-methylethyl)benzoate
872091-85-5

methyl 3-(1-cyano-1-methylethyl)benzoate

Conditions
ConditionsYield
In dimethyl sulfoxide79%
Stage #1: methyl 3-cyanomethylbenzoate With sodium hydride In dimethyl sulfoxide; mineral oil at 20 - 25℃;
Stage #2: methyl iodide In dimethyl sulfoxide; mineral oil at 20℃; for 16h;
79%
Stage #1: methyl 3-cyanomethylbenzoate With sodium hydride In dimethyl sulfoxide; mineral oil at 20℃; for 0.333333h; Cooling with ice;
Stage #2: methyl iodide In dimethyl sulfoxide; mineral oil at 20℃; for 16h;
79%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

3-(2-Amino-ethyl)-benzoic acid methyl ester
179003-00-0

3-(2-Amino-ethyl)-benzoic acid methyl ester

Conditions
ConditionsYield
With hydrogenchloride; palladium 10% on activated carbon In methanol; water at 20℃; for 2h; Inert atmosphere;78%
With sodium tetrahydroborate; trifluoroacetic acid In tetrahydrofuran for 4h; Ambient temperature;
With hydrogen; palladium on activated charcoal
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

ethylene dibromide
106-93-4

ethylene dibromide

methyl 3-(1-cyanocyclopropyl)benzoate
884000-93-5

methyl 3-(1-cyanocyclopropyl)benzoate

Conditions
ConditionsYield
With dimethyl sulfoxide76%
Stage #1: methyl 3-cyanomethylbenzoate With sodium hydride In dimethyl sulfoxide; mineral oil at 20 - 25℃;
Stage #2: ethylene dibromide In dimethyl sulfoxide; mineral oil at 20℃; for 10h;
76%
Stage #1: methyl 3-cyanomethylbenzoate With sodium hydride In dimethyl sulfoxide; mineral oil at 20℃; for 0.333333h; Cooling with ice;
Stage #2: ethylene dibromide In dimethyl sulfoxide; mineral oil at 20℃; for 16h;
76%
Stage #1: methyl 3-cyanomethylbenzoate With sodium hydride In dimethyl sulfoxide; mineral oil at 20 - 25℃; for 0.5h;
Stage #2: ethylene dibromide In dimethyl sulfoxide; mineral oil at 20℃; for 16h;
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

methyl 3-(2-amino-2-oxoethyl)benzoate
929301-93-9

methyl 3-(2-amino-2-oxoethyl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 3-cyanomethylbenzoate With hydrogenchloride In tetrahydrofuran; water
Stage #2: With sodium hydroxide In tetrahydrofuran; water
70%
1,5-dibromo-pentane
111-24-0

1,5-dibromo-pentane

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

methyl 3-(1-cyanocyclohexyl)benzoate
1005788-17-9

methyl 3-(1-cyanocyclohexyl)benzoate

Conditions
ConditionsYield
With dimethyl sulfoxide68%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

1-Bromo-2-chloroethane
107-04-0

1-Bromo-2-chloroethane

methyl 3-(1-cyanocyclopropyl)benzoate
884000-93-5

methyl 3-(1-cyanocyclopropyl)benzoate

Conditions
ConditionsYield
Stage #1: methyl 3-cyanomethylbenzoate With sodium hydride In dimethyl sulfoxide; mineral oil
Stage #2: 1-Bromo-2-chloroethane In dimethyl sulfoxide; mineral oil at 0 - 25℃; for 18h;
68%
With sodium hydride In dimethyl sulfoxide; mineral oil at 0 - 25℃; for 18h;68%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

3-carboxymethyl-benzoic acid
2084-13-1

3-carboxymethyl-benzoic acid

Conditions
ConditionsYield
With sulfuric acid; water at 160℃; for 3h;68%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

methyl 3-(1-cyano-1-methylethyl)benzoate
872091-85-5

methyl 3-(1-cyano-1-methylethyl)benzoate

Conditions
ConditionsYield
With sodium hydride In dimethyl sulfoxide at 0 - 25℃; for 12h;66%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

[2-(3-methoxycarbonylphenyl)ethyl]ammonium chloride

[2-(3-methoxycarbonylphenyl)ethyl]ammonium chloride

Conditions
ConditionsYield
With hydrogenchloride; palladium 10% on activated carbon; hydrogen In methanol; water63%
With hydrogenchloride; hydrogen; palladium 10% on activated carbon In methanol; dichloromethane; water at 20℃; under 2585.81 Torr; for 10h;
With hydrogenchloride; hydrogen; palladium 10% on activated carbon In methanol; dichloromethane; water at 20℃; under 2585.81 Torr; for 10h;
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

4-bromo-3-(cyanomethyl)benzoic acid methyl ester

4-bromo-3-(cyanomethyl)benzoic acid methyl ester

Conditions
ConditionsYield
With N-Bromosuccinimide; palladium diacetate; copper(II) bis(trifluoromethanesulfonate) In 1,2-dichloro-ethane Inert atmosphere; Sealed tube; regioselective reaction;52%
1,1'-oxybis(2-bromo-ethane)
5414-19-7

1,1'-oxybis(2-bromo-ethane)

methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

methyl 3-(4-cyanotetrahydro-2H-pyran-4-yl)benzoate
884000-92-4

methyl 3-(4-cyanotetrahydro-2H-pyran-4-yl)benzoate

Conditions
ConditionsYield
With dimethyl sulfoxide46%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

1,3-dibromo-propane
109-64-8

1,3-dibromo-propane

methyl 3-(1-cyanocyclobutyl)benzoate
884000-91-3

methyl 3-(1-cyanocyclobutyl)benzoate

Conditions
ConditionsYield
With dimethyl sulfoxide42%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

2-(3-((2,4-dichlorophenoxy)methyl)phenyl)acetic acid

2-(3-((2,4-dichlorophenoxy)methyl)phenyl)acetic acid

Conditions
ConditionsYield
Stage #1: methyl 3-cyanomethylbenzoate With sodium tetrahydroborate In tetrahydrofuran at 80℃;
Stage #2: With methanol In tetrahydrofuran at 20 - 80℃; for 16.5h;
40%
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

3-carbamimidoylmethyl-benzoic acid methyl ester hydrochloride

3-carbamimidoylmethyl-benzoic acid methyl ester hydrochloride

Conditions
ConditionsYield
With hydrogenchloride; ethanol; ammonia 1.) CH2Cl2, EtOH, 0 deg C, 6 days, 2.) MeOH, 50 deg C, 18 h; Multistep reaction;
With ammonia In methanol; ethanol; dichloromethane
methyl 3-cyanomethylbenzoate
68432-92-8

methyl 3-cyanomethylbenzoate

acrylic acid methyl ester
292638-85-8

acrylic acid methyl ester

C18H21NO6

C18H21NO6

Conditions
ConditionsYield
With N-benzyl-trimethylammonium hydroxide In acetonitrile Michael reaction; Heating;

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