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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine Manufacturer/High quality/Best price/In stock

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 3-Chloro-2-Fluoro-5-(Trifluoromethyl)Pyridine supplier in China

Cas:72537-17-8

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

2-Fluoro-3-Chloro-5-Trifluoromethylpyridine

Cas:72537-17-8

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

3-Chloro-2-fluoro-5-(trifluoromethyl)-pyridine

Cas:72537-17-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

1 Factory price 2 High quality 3 Good service Appearance:Powder Storage:Dry and cold condition Package:25KG, 500KG and1000KG, seaworthy and suitable for container transportation. Application:coatings, printing ink, rubber, glass, leather, cos

72537-17-8 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

Cas:72537-17-8

Min.Order:20 Metric Ton

FOB Price: $2100.0

Type:Trading Company

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 72537-17-8 with fast shipping

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:72537-17-8

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biological Technology Co., Ltd. is specialize in the production of chemical raw materials and reagents,located in Shijiazhuang, Hebei Province. In recent decades, under the efforts of all staff, in Shandong, Henan, Guangdong and many othe

3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Triumph International Development Limilted

Appearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:As customer request Port:Qingda

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE 72537-17-8

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine

Cas:72537-17-8

Min.Order:0 Metric Ton

Negotiable

Type:Other

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

3-(3,5-Dichlorophenyl)-3-oxo-propionic acid ethyl ester

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Cas:72537-17-8

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Cas:72537-17-8

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Colorless or light yellow liquid or crystal Storage:keep cool and dry place Package:25kg/drum, or as per your request. Application:For medicine , pesticide intermediates Transpor

3-Chloro-2-fluoro-5-(trifluoromethyl)pyridine

Cas:72537-17-8

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

YUNBIO TECH CO.,LTD

Our Strength:-Flexible: We work in small teams with rapid communication channels. Respond quickly and efficiently to customer and market needs.-Innovative: We are focusing on the development of new products and keep close relationships with our custo

2-FLUORO-3-CHLORO-5-(TRIFLUOROMETHYL) PYRIDINE

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Product Name: 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE Synonyms: 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE;2-FLUORO-3-CHLORO-5-(TRIFLUOROMETHYL)PYRIDINE;CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE;3-Chloro-2-fluoro-5-(trifluoromethy

TIANFU-CHEM 3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Cas:72537-17-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Minstar Chemical Co., Ltd

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE Chemical Properties Melting point 16-20 °C (lit.) Boiling point 50-55 °C/11 mmHg (lit.) density 1.524 g/mL at 25 °C (lit.) refractive index n20/D 1.433(lit.) Fp 125 °F

2-Fluoro-3-chloro-5-trifluoromethylpyridine

Cas:72537-17-8

Min.Order:200 Kilogram

FOB Price: $65.0

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

3-CHLORO-2-FLUORO-5-(TRIFLUOROMETHYL)PYRIDINE

Cas:72537-17-8

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe

SAGECHEM/2-Fluoro-3-chloro-5-trifluoromethylpyridine

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Beijing Greenchem Technology Co.,Ltd. ( Panjin Greenchem Technology Co.Ltd .)

Capability on chemical synthesis1. Beijing High-Tech Enterprises2. Strong R&D Team3. 8 years of experiences in R & D of high-tech Catalyst;4. 5000 production techniques, 69 items of national patents, and 360 kinds of products on sales;5. The producti

2-Fluoro-3-chloro-5-trifluoromethylpyridine

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

3-chloro-2-fluoro-5-(trifluoromethyl)-pyridine CAS 72537-17-8

Cas:72537-17-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

3-chloro-2-fluoro-5-(trifluoromethyl)pyridine cas no. 72537-17-8 97%

Cas:72537-17-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,3-dichloro-5-trifluoromethylpyridine
69045-84-7

2,3-dichloro-5-trifluoromethylpyridine

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With potassium carbonate; cesium fluoride In dimethyl sulfoxide at 120℃; under 18.7519 - 22.5023 Torr; for 4h; Product distribution / selectivity;100%
With potassium carbonate; cesium fluoride In 1-methyl-pyrrolidin-2-one at 70℃; for 1 - 3h; Product distribution / selectivity;98%
With potassium fluoride; N-benzyl-N,N,N-triethylammonium chloride In N,N-dimethyl acetamide at 170℃; for 5h; Temperature;97%
2-amino-3-chloro-5-(trifluoromethyl)pyridine
79456-26-1

2-amino-3-chloro-5-(trifluoromethyl)pyridine

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With pyridine hydrogenfluoride; sodium nitrite 1.) O deg C, 20 min, 2.) 20 deg C, 1 h;99%
With pyridine; hydrogen fluoride; sodium nitrite 1.) 0 deg C, 30 min; 2.) 20 deg C, 1 h; Yield given. Multistep reaction;
2,3-dichloro-5-(trichloromethyl)pyridine
69045-83-6

2,3-dichloro-5-(trichloromethyl)pyridine

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
Stage #1: 2,3-dichloro-5-(trichloromethyl)pyridine under 75007.5 Torr; for 6h; Autoclave; Inert atmosphere;
Stage #2: With hydrogen fluoride at -5 - 185℃; for 12h; Temperature; Autoclave;
97.56%
With hydrogen fluoride; antimony pentafluoride at 180℃; under 45004.5 Torr; for 24h; Temperature; Pressure; Large scale;
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

2-amino-3-chloro-5-(trifluoromethyl)pyridine
79456-26-1

2-amino-3-chloro-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With ammonia In tetrahydrofuran at 35℃; under 1950.2 Torr; for 28h; Product distribution / selectivity; Autoclave; Inert atmosphere;99.5%
With acetamidine hydrochloride; sodium hydroxide In water; dimethyl sulfoxide at 130℃; for 24h; Schlenk technique; chemoselective reaction;94%
With ammonia In tetrahydrofuran at 30℃; under 3750.38 - 6750.68 Torr; for 30h; Temperature; Pressure; Autoclave; Inert atmosphere;
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

(2,3-difluorophenyl)boronic acid
121219-16-7

(2,3-difluorophenyl)boronic acid

3-(2,3-difluorophenyl)-2-fluoro-5-trifluoromethylpyridine

3-(2,3-difluorophenyl)-2-fluoro-5-trifluoromethylpyridine

Conditions
ConditionsYield
With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate; palladium diacetate In toluene at 90℃; for 16h; Suzuki-Miyaura coupling;96%
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

(2,3-dimethylphenyl)zinc chloride

(2,3-dimethylphenyl)zinc chloride

3-(2,3-dimethylphenyl)-2-fluoro-5-trifluoromethylpyridine

3-(2,3-dimethylphenyl)-2-fluoro-5-trifluoromethylpyridine

Conditions
ConditionsYield
With tris(dibenzylideneacetone)dipalladium (0); ruphos In tetrahydrofuran at 70℃; for 15h; Negishi coupling;92%
acetamidine hydrochloride
124-42-5

acetamidine hydrochloride

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetamide

N-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)acetamide

Conditions
ConditionsYield
With water; caesium carbonate In dimethyl sulfoxide at 90℃; for 18h; Schlenk technique; chemoselective reaction;92%
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

3-chloro-2-cyano-5-(trifluoromethyl)pyridine
80194-70-3

3-chloro-2-cyano-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With potassium cyanide; Aliquat 336 In water at 30℃; for 5h;90%
With sodium cyanide; tetrabutylammomium bromide at 20 - 25℃; for 23h;82%
sodium cyanide
773837-37-9

sodium cyanide

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

3-chloro-2-cyano-5-(trifluoromethyl)pyridine
80194-70-3

3-chloro-2-cyano-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
Stage #1: 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine With dmap In acetone for 5h; Reflux; Large scale;
Stage #2: sodium cyanide In chloroform; water at 20℃; for 2.5h; Large scale;
89%
dmap In water; propiononitrile at 20℃; for 5h;83%
With tetrabutylammomium bromide In water; dimethyl sulfoxide at 45 - 50℃; Concentration;74.3%
With N-benzyl-N,N,N-triethylammonium chloride at 20℃; for 10h; Temperature;46.7 g
4,5-dibromo-2H-1,2,3-triazole
22300-52-3

4,5-dibromo-2H-1,2,3-triazole

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

C8H2Br2ClF3N4
1192847-40-7

C8H2Br2ClF3N4

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; regioselective reaction;89%
potassium cyanide

potassium cyanide

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

A

butanedinitrile
110-61-2

butanedinitrile

B

3-chloro-2-cyano-5-(trifluoromethyl)pyridine
80194-70-3

3-chloro-2-cyano-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With dmap In water at 75 - 78℃; for 12h; Reagent/catalyst; Temperature;A 81.8%
B 86.7%
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

(R)-2-(4-hydroxyphenoxy)propionic acid
94050-90-5

(R)-2-(4-hydroxyphenoxy)propionic acid

butan-1-ol
71-36-3

butan-1-ol

haloxyf-ethoxyethyl
99320-80-6

haloxyf-ethoxyethyl

Conditions
ConditionsYield
Stage #1: 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine; (R)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 50 - 60℃; for 2h;
Stage #2: With 1,3,5-trichloro-2,4,6-triazine In N,N-dimethyl-formamide at 5 - 25℃; for 1.16667h;
Stage #3: butan-1-ol In N,N-dimethyl-formamide
86%
potassium cyanide
151-50-8

potassium cyanide

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

3-chloro-2-cyano-5-(trifluoromethyl)pyridine
80194-70-3

3-chloro-2-cyano-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
In dimethyl sulfoxide at 30℃; for 0.833333h;84%
cyclohexyl zinc iodide
121883-35-0

cyclohexyl zinc iodide

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

3-cyclohexyl-2-fluoro-5-(trifluoromethyl)pyridine
1160556-51-3

3-cyclohexyl-2-fluoro-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With 2′-(dicyclohexylphophanyl)-N2,N2,N6,N6-tetramethyl[1,1′-biphenyl]-2,6-diamine; palladium diacetate In tetrahydrofuran; toluene at 60℃; for 1h; Negishi coupling reaction; Inert atmosphere;84%
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

[1(2H)-3-chloro-5-(trifluoromethyl)-3'-chloro-5'-(trifluoromethyl)-2'-bipyridin]-2-one
96741-18-3

[1(2H)-3-chloro-5-(trifluoromethyl)-3'-chloro-5'-(trifluoromethyl)-2'-bipyridin]-2-one

Conditions
ConditionsYield
With water; sodium hydroxide In dimethyl sulfoxide at 110℃; for 12h;83%
methanol
67-56-1

methanol

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

(R)-2-(4-hydroxyphenoxy)propionic acid
94050-90-5

(R)-2-(4-hydroxyphenoxy)propionic acid

(R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid methyl ester
72619-32-0

(R)-2-[4-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acid methyl ester

Conditions
ConditionsYield
Stage #1: 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine; (R)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 50 - 60℃; for 2h;
Stage #2: With 1,3,5-trichloro-2,4,6-triazine In N,N-dimethyl-formamide at 5 - 25℃; for 1.16667h;
Stage #3: methanol In N,N-dimethyl-formamide
80%
furan-3-boronic acid
55552-70-0

furan-3-boronic acid

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

2-fluoro-3-(furan-3-yl)-5-(trifluoromethyl)pyridine
1251914-15-4

2-fluoro-3-(furan-3-yl)-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With potassium phosphate; chloro(2-dicyclohexylphosphino-2’,4’,6’-triisopropyl-1,1‘-biphenyl)[2-(2’-amino-1,1‘-biphenyl’)]palladium(II) In tetrahydrofuran; water at 40℃; for 0.5h; Suzuki-Miyaura cross-coupling; Inert atmosphere;78%
2-ethoxy-ethanol
110-80-5

2-ethoxy-ethanol

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

(R)-2-(4-hydroxyphenoxy)propionic acid
94050-90-5

(R)-2-(4-hydroxyphenoxy)propionic acid

haloxyfop-etotyl

haloxyfop-etotyl

Conditions
ConditionsYield
Stage #1: 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine; (R)-2-(4-hydroxyphenoxy)propionic acid With potassium phosphate; tetra-(n-butyl)ammonium iodide In N,N-dimethyl-formamide at 50 - 60℃; for 2h;
Stage #2: With 1,3,5-trichloro-2,4,6-triazine In N,N-dimethyl-formamide at 5 - 25℃; for 1.16667h;
Stage #3: 2-ethoxy-ethanol In N,N-dimethyl-formamide
78%
(+)-(1S,2R,4R)-tert-butyl 2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate
500556-90-1

(+)-(1S,2R,4R)-tert-butyl 2-amino-7-azabicyclo[2.2.1]heptane-7-carboxylate

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

(1S,2R,4R)-tert-butyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-7-azabicyclo[2.2.1]heptane-7-carboxylate

(1S,2R,4R)-tert-butyl 2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)amino)-7-azabicyclo[2.2.1]heptane-7-carboxylate

Conditions
ConditionsYield
With triethylamine In acetonitrile for 16h; Microwave irradiation; Inert atmosphere; Reflux;78%
Sesamol
533-31-3

Sesamol

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

2-[5-(1,3-benzodioxolyl)oxy]-3-chloro-5-(trifluoromethyl)pyridine

2-[5-(1,3-benzodioxolyl)oxy]-3-chloro-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
With potassium carbonate In dimethyl sulfoxide at 20℃; for 4h;77%
1-(1-Cyclohexen-1-yl)pyrrolidine
1125-99-1

1-(1-Cyclohexen-1-yl)pyrrolidine

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]cyclohexanone
868234-81-5

2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]cyclohexanone

Conditions
ConditionsYield
at 20 - 100℃; for 84h; Neat (no solvent);72%
Stage #1: 1-(1-Cyclohexen-1-yl)pyrrolidine; 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine at 20 - 100℃; for 84h;
Stage #2: With sulfuric acid In water
72%
hydroquinone
123-31-9

hydroquinone

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

2-(4'-hydroxyphenoxy)-3-chloro-5-trifluoromethylpyridine
69045-89-2

2-(4'-hydroxyphenoxy)-3-chloro-5-trifluoromethylpyridine

Conditions
ConditionsYield
With sodium hydroxide In dimethyl sulfoxide70%
2',4'-dihydroxy-4-acetophenone
89-84-9

2',4'-dihydroxy-4-acetophenone

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

1-[4-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)-2-hydroxyphenyl]ethanone
451456-58-9

1-[4-((3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy)-2-hydroxyphenyl]ethanone

Conditions
ConditionsYield
With potassium carbonate In acetonitrile for 2h; Heating;65%
methanol
67-56-1

methanol

carbon monoxide
201230-82-2

carbon monoxide

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

A

methyl 2-methoxy-5-(trifluoromethyl)nicotinate

methyl 2-methoxy-5-(trifluoromethyl)nicotinate

B

dimethyl 5-(trifluoromethyl)pyridine-2,3-dicarboxylate

dimethyl 5-(trifluoromethyl)pyridine-2,3-dicarboxylate

Conditions
ConditionsYield
With dichloro[2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II); triethylamine at 100℃; under 2585.74 Torr; for 14h;A 60%
B 10%
(S)-tert-butyl 6-(aminomethyl)-5-azaspiro[2.4]heptane-5-carboxylate
1262397-26-1

(S)-tert-butyl 6-(aminomethyl)-5-azaspiro[2.4]heptane-5-carboxylate

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

C18H23ClF3N3O2
1445595-86-7

C18H23ClF3N3O2

Conditions
ConditionsYield
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 100 - 150℃; Microwave irradiation;60%
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 100 - 150℃; Microwave irradiation;60%
4-(1-cyclohepten-1-yl)morpholine
7182-08-3

4-(1-cyclohepten-1-yl)morpholine

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]cycloheptanone
868234-82-6

2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]cycloheptanone

Conditions
ConditionsYield
at 120℃; for 3h; Neat (no solvent);58%
Stage #1: 4-(1-cyclohepten-1-yl)morpholine; 2-fluoro-3-chloro-5-(trifluoromethyl)pyridine at 120℃; for 3h;
Stage #2: With sulfuric acid In water
58%
N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

3-chloro-N,N-dimethyl-5-(trifluoromethyl)pyridin-2-amine
157071-79-9

3-chloro-N,N-dimethyl-5-(trifluoromethyl)pyridin-2-amine

Conditions
ConditionsYield
With potassium hydroxide In neat (no solvent) at 100℃; for 24h; Sealed tube; regioselective reaction;57%
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

3-chloro-2-[4-(prop-2-enyloxy)phenoxy]-5-(trifluoromethyl)pyridine
451456-48-7

3-chloro-2-[4-(prop-2-enyloxy)phenoxy]-5-(trifluoromethyl)pyridine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 70 percent / aq. NaOH / dimethylsulfoxide
2: 86 percent / K2CO3 / dimethylformamide / 0.5 h / 70 °C
View Scheme
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

4-[(3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy]-2-(hydroxymethyl)phenol
451456-45-4

4-[(3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy]-2-(hydroxymethyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 70 percent / aq. NaOH / dimethylsulfoxide
2: 57 percent / propanoic acid / benzene / 3 h / Heating
3: 82 percent / 30 percent H2O2 / tetrahydrofuran / 2 h / 20 °C
View Scheme
2-fluoro-3-chloro-5-(trifluoromethyl)pyridine
72537-17-8

2-fluoro-3-chloro-5-(trifluoromethyl)pyridine

4-[(3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy]-2-(prop-2-enyl)phenol
451456-50-1

4-[(3-chloro-5-(trifluoromethyl)-2-pyridinyl)oxy]-2-(prop-2-enyl)phenol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 70 percent / aq. NaOH / dimethylsulfoxide
2: 86 percent / K2CO3 / dimethylformamide / 0.5 h / 70 °C
3: 84 percent / 2 h / 210 - 215 °C
View Scheme

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