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Tianjin Kind Pharma Co., Ltd.

Factory direct sales, accept customization. Pyrroloquinoline quinone is an important growth factor for the body and a redox/cofactor found in a a class of enzymes called quinoproteins. It is a cofactor of microbial quinoprotein enzyme, and imidazopy

Pyrroloquinoline Quinone PQQ

Cas:72909-34-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Pyrroloquinoline quinone PQQ

Cas:72909-34-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Leader Biochemical Group

PRODUCT DETAILS Pyrro

Hot Sales!!!!!!!!!+China Biggest Manufacturer supply PQQ (Pyrroloquinoline Quinone)

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

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Binbo Biological Co., Ltd

1.high purity 2.consistent quality 3.competitive price 4.fast shipping Binbo Biological Products Co. Ltd., is a professional high-tech enterprise which engaged in Biological products. Binbo is engaged in R&D with perfect equipments and advan

Pyrroloquinoline Quinone / PQQ CAS 72909-34-3

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $100.0 / 200.0

Type:Lab/Research institutions

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Luyunjia Chemistry Xiamen Limited

ProName: Pyrroloquinoline quinone 72909-34-3 CasNo: 72909-34-3 Molecular Formula: C14H6N2O8 Appearance: Orange-Red Solid Application: NA DeliveryTime: With about 7-15 days after receipt the... PackAge: 1KG-200KG Drum with pallet Port: China

lower price Pyrroloquinoline quinone 72909-34-3

Cas:72909-34-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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DB BIOTECH CO., LTD

Q1: Are you a manufacturer Answer: Yes, we are factory founded on 2012.Q2: How to contact with us Click "contact supplier" And then send us message the product you interest in, you will get reply within 12 hours.Q3:Which kind of payment terms do you

PQQ, Methoxatin, Pyrroloquinoline, 72909-34-3

Cas:72909-34-3

Min.Order:0

Negotiable

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Pyrroloquinoline quinone in stock

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Hubei Vanz Pharm Co.,Ltd

Wuhan Vanz Pharm Inc CAS 72909-34-3 pyrroloquinoline quinone pqq powder. PQQ The scientific name of the PQQ pyrroloquinoline quinone (PQQ) pyrroloquinoline quinone is a new prosthetic group, is the second flavin nucleotides (FMN, FAD) and nic

Manufacturer Supply Top Quality CAS 72909-34-3 pyrroloquinoline quinone pqq powder

Cas:72909-34-3

Min.Order:10 Gram

FOB Price: $4.5 / 10.0

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

High purity 99% factory price Pyrroloquinoline Quinone PQQ

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $25.0 / 800.0

Type:Trading Company

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Kono Chem Co.,Ltd

Application • As a powerful antioxidant, PQQ protects and increases the functionality of existing mitochondria -Slowing mitochondrial aging. • PQQ also promotes the generation of new mitochondria (Mitochondrial Biogenesis).

CAS No.:72909-34-3 pyrroloquinoline quinine

Cas:72909-34-3

Min.Order:1 Kilogram

Negotiable

Type:Other

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Hebei yanxi chemical co.,LTD.

Hebei yanxi chemical co., LTD is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low carb

Healthy Supplements Pyrroloquinoline Quinone

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

High quality Pyrroloquinoline quinone CAS 72909-34-3 with factory price Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Fe

High quality Pyrroloquinoline quinone CAS 72909-34-3 with factory price

Cas:72909-34-3

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

99% Pyrroloquinoline Quinone PQQ Powder CAS 72909-34-3

Cas:72909-34-3

Min.Order:50 Gram

FOB Price: $4.5 / 8.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Pyrroloquinoline quinone manufacturer with low price

Cas:72909-34-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Pyrroloquinoline quinone 72909-34-3 GMP Manufacturer

Cas:72909-34-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.

Our products are of good quality, exquisite workmanship and reasonable price, and our after-sales service is good, which can be guaranteed. Our chief line is the export of API. We have been in this line of API since 2005. Many of our products are be

Pyrroloquinoline quinone 98%

Cas:72909-34-3

Min.Order:5 Gram

Negotiable

Type:Manufacturers

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Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Pyrroloquinoline quinone

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

PQQ

Cas:72909-34-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Pyrroloquinoline quinone CAS72909-34-3 Methoxatin 1H-Pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylicacid, 4,5-dihydro-4,5-dioxo- CAS no 72909-34-3 PQQ disodium salt 1-Naphthol Manufacturer High quality Best price In stock factory CAS 72909-34-3 1-N

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so

Pyrroloquinoline quinone 72909-34-3

Cas:72909-34-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

PQQ CAS 72909-34-3 Pyrroloquinoline Quinone Powder

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 72909-34-3 with competitive price

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: High quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Buy China Manufacturer Best Price Pyrroloquinoline quinone CAS 72909-34-3 With Fast Delivery

Cas:72909-34-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time

High Quality 72909-34-3 low price Methoxatin

Cas:72909-34-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Sinotech Import&Export Corporation

Product Name: Pyrroloquinoline quinone Synonyms: PQQ Cofactor, Pyrroloquinoline quinone, 4,5-Dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid;Pyrroloquinoline quinone ,98%;Coenzime PQQ;

Pyrroloquinoline quinone

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Henan Wentao Chemical Product Co., Ltd.

we are leading fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.Our main business covers the fields below: 1.Noble Metal Catalysts (Pt.Pd...) 2.Orga

Pyrroloquinoline quinone CAS NO.: 72909-34-3

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $0.2 / 1.0

Type:Lab/Research institutions

inquiry

Antimex Chemical Limied

Pyrroloquinoline quinone Pyrroloquinoline quinone ; PQQ manufacture, good supplier in China, We are one of reliable manufacturer and supplier of chemicals in China , our own R&D center offer custom synthesis according to the contract resea

PQQ Pyrroloquinoline quinone

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High quality gua

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

Pqq Manufacturer High Quality Pyrroloquinoline Quinone PQQ CAS 72909-34-3 With Rapid Logistics

Cas:72909-34-3

Min.Order:1 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

inquiry

Synthetic route

trimethyl 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate
74447-88-4

trimethyl 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
With sodium carbonate In water at 30℃; for 24h;100%
With water; potassium carbonate In water at 25 - 80℃; Green chemistry; Industrial scale;91%
With potassium carbonate In water at 25 - 80℃; for 12h;91%
5,5-Dimethoxy-4-oxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester
78939-40-9

5,5-Dimethoxy-4-oxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
With potassium carbonate In water at 85℃; for 4h;98%
4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester
80721-47-7

4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Stage #1: 4,5-Dihydro-4,5-dioxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester With lithium hydroxide; water In tetrahydrofuran at 0 - 17℃; for 31.5h;
Stage #2: With hydrogenchloride; potassium chloride In tetrahydrofuran; water at 0℃; for 1h; pH=5.3 - 6;
Stage #3: With sulfuric acid In water at 20℃; for 2.5h;
97%
With lithium hydroxide In tetrahydrofuran; water at 25℃; for 6h;89%
With lithium hydroxide In tetrahydrofuran for 6.5h;89%
4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid
79127-57-4

4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
With dihydrogen peroxide at 35℃; for 24h;86.5%
With acetate and phosphate buffer; potassium chloride; oxygen In water; dimethyl sulfoxide at 30℃; Rate constant; Kinetics; Mechanism;
5-Methoxy-1H-pyrrolo<2,3-f>quinoline-2,7,9-tricarboxylic acid
116451-31-1

5-Methoxy-1H-pyrrolo<2,3-f>quinoline-2,7,9-tricarboxylic acid

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
With ammonium cerium (IV) nitrate In 1,2-dichloro-ethane at 25℃; for 24h;19.01%
5-Methoxy-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester
133706-80-6

5-Methoxy-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C
2: 63 percent / LiOH*H2O / tetrahydrofuran; H2O / 20.5 h / Ambient temperature; purification with conc. H2SO4
View Scheme
Multi-step reaction with 2 steps
1: copper(II) acetate monohydrate / water / 1 h / -5 °C
2: lithium hydroxide monohydrate / water; tetrahydrofuran / 32 h / 16 °C
View Scheme
6-amino-5-methoxy-2-ethoxycarbonylindole
107575-60-0

6-amino-5-methoxy-2-ethoxycarbonylindole

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 73 percent / CH2Cl2 / 8 h / Ambient temperature
2: 94.5 percent / Cu(OAc)2*H2O, HCl(g)/air / CH2Cl2
3: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C
4: 63 percent / LiOH*H2O / tetrahydrofuran; H2O / 20.5 h / Ambient temperature; purification with conc. H2SO4
View Scheme
Multi-step reaction with 3 steps
1.1: dichloromethane / 12 h / 20 °C
1.2: 8 h / 20 °C
2.1: copper(II) acetate monohydrate / water / 1 h / -5 °C
3.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 32 h / 16 °C
View Scheme
6-(Formylamino)-5-methoxyindol-2-carbonsaeure-ethylester
119825-27-3

6-(Formylamino)-5-methoxyindol-2-carbonsaeure-ethylester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 84.5 percent / 18percent aq. HCl / acetone / 4 h / 80 °C
2: 73 percent / CH2Cl2 / 8 h / Ambient temperature
3: 94.5 percent / Cu(OAc)2*H2O, HCl(g)/air / CH2Cl2
4: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C
5: 63 percent / LiOH*H2O / tetrahydrofuran; H2O / 20.5 h / Ambient temperature; purification with conc. H2SO4
View Scheme
Multi-step reaction with 4 steps
1.1: 1-(3-sulfopropyl)pyridinium phosphotungstate; benzylamine / 1.5 h / 140 °C / Microwave irradiation
2.1: dichloromethane / 12 h / 20 °C
2.2: 8 h / 20 °C
3.1: copper(II) acetate monohydrate / water / 1 h / -5 °C
4.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 32 h / 16 °C
View Scheme
4-oxo-pent-2-enedioic acid dimethyl ester
78939-37-4

4-oxo-pent-2-enedioic acid dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 73 percent / CH2Cl2 / 8 h / Ambient temperature
2: 94.5 percent / Cu(OAc)2*H2O, HCl(g)/air / CH2Cl2
3: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C
4: 63 percent / LiOH*H2O / tetrahydrofuran; H2O / 20.5 h / Ambient temperature; purification with conc. H2SO4
View Scheme
Multi-step reaction with 5 steps
1: CH2Cl2 / 7 h / 25 °C
2: dry hydrogen chloride / CH2Cl2 / 10 h
3: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
4: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
5: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
Multi-step reaction with 3 steps
1.1: dichloromethane / 12 h / 20 °C
1.2: 8 h / 20 °C
2.1: copper(II) acetate monohydrate / water / 1 h / -5 °C
3.1: lithium hydroxide monohydrate / water; tetrahydrofuran / 32 h / 16 °C
View Scheme
Multi-step reaction with 5 steps
1: sulfuric acid / dichloromethane / 5 h / Reflux
2: potassium carbonate / 2-methyltetrahydrofuran / 5 h / Reflux
3: zinc; acetic acid / 10 h / 50 °C
4: sodium hydroxide / 24 h / 25 °C
5: ammonium cerium (IV) nitrate / 1,2-dichloro-ethane / 24 h / 25 °C
View Scheme
cis-6,7,8,9-Tetrahydro-9-hydroxy-5-methoxy-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester

cis-6,7,8,9-Tetrahydro-9-hydroxy-5-methoxy-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure-(2-ethyl)(7,9-dimethyl)ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 94.5 percent / Cu(OAc)2*H2O, HCl(g)/air / CH2Cl2
2: 69 percent / Ce(NH4)2(NO3)6 / acetonitrile; H2O / 0.5 h / -3 °C
3: 63 percent / LiOH*H2O / tetrahydrofuran; H2O / 20.5 h / Ambient temperature; purification with conc. H2SO4
View Scheme
ethyl 5-hydroxyindole-2-carboxylate
24985-85-1

ethyl 5-hydroxyindole-2-carboxylate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 94 percent / Fremy's salt, KH2PO4 / acetonitrile; H2O / 0.5 h / 20 °C
2: 47 percent / Et3N / tetrahydrofuran / 1 h / 20 °C
3: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
4: 85 percent / trifluoroacetic acid / 1 h / 20 °C
5: 82 percent / chlorobenzene / 4 h / 131 °C
6: LiOH
View Scheme
Multi-step reaction with 7 steps
1: 94 percent / Fremy's salt, KH2PO4 / acetonitrile; H2O / 0.5 h / 20 °C
2: 47 percent / Et3N / tetrahydrofuran / 1 h / 20 °C
3: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
4: Et3N, MnO2 / CH2Cl2
5: 85 percent / trifluoroacetic acid / 1 h / 20 °C
6: 82 percent / chlorobenzene / 4 h / 131 °C
7: LiOH
View Scheme
4-Hydroxy-5-oxo-5H-indole-2-carboxylic acid ethyl ester
98126-24-0

4-Hydroxy-5-oxo-5H-indole-2-carboxylic acid ethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 47 percent / Et3N / tetrahydrofuran / 1 h / 20 °C
2: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
3: 85 percent / trifluoroacetic acid / 1 h / 20 °C
4: 82 percent / chlorobenzene / 4 h / 131 °C
5: LiOH
View Scheme
Multi-step reaction with 6 steps
1: 47 percent / Et3N / tetrahydrofuran / 1 h / 20 °C
2: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
3: Et3N, MnO2 / CH2Cl2
4: 85 percent / trifluoroacetic acid / 1 h / 20 °C
5: 82 percent / chlorobenzene / 4 h / 131 °C
6: LiOH
View Scheme
2-Benzyloxycarbonylamino-4-nitro-pentanedioic acid dimethyl ester
204922-65-6

2-Benzyloxycarbonylamino-4-nitro-pentanedioic acid dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: 47 percent / Et3N / tetrahydrofuran / 1 h / 20 °C
2: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
3: 85 percent / trifluoroacetic acid / 1 h / 20 °C
4: 82 percent / chlorobenzene / 4 h / 131 °C
5: LiOH
View Scheme
Multi-step reaction with 6 steps
1: 47 percent / Et3N / tetrahydrofuran / 1 h / 20 °C
2: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
3: Et3N, MnO2 / CH2Cl2
4: 85 percent / trifluoroacetic acid / 1 h / 20 °C
5: 82 percent / chlorobenzene / 4 h / 131 °C
6: LiOH
View Scheme
6-Chloro-4-hydroxy-7-[methoxycarbonyl-(4-methoxycarbonyl-2-oxo-2,3-dihydro-oxazol-5-yl)-methyl]-5-oxo-5H-indole-2-carboxylic acid ethyl ester
98126-30-8

6-Chloro-4-hydroxy-7-[methoxycarbonyl-(4-methoxycarbonyl-2-oxo-2,3-dihydro-oxazol-5-yl)-methyl]-5-oxo-5H-indole-2-carboxylic acid ethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 82 percent / chlorobenzene / 4 h / 131 °C
2: LiOH
View Scheme
2-Benzyloxycarbonylamino-4-[2-ethoxycarbonyl-5-hydroxy-4-oxo-1,4-dihydro-indol-(7Z)-ylidene]-pentanedioic acid dimethyl ester

2-Benzyloxycarbonylamino-4-[2-ethoxycarbonyl-5-hydroxy-4-oxo-1,4-dihydro-indol-(7Z)-ylidene]-pentanedioic acid dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
2: 85 percent / trifluoroacetic acid / 1 h / 20 °C
3: 82 percent / chlorobenzene / 4 h / 131 °C
4: LiOH
View Scheme
Multi-step reaction with 5 steps
1: 1.) N-chlorosuccinimide, triethylamine; 2.) DDQ, Et3N / 1.) methylene chloride, 20 deg C, 30 min; 2.) methylene chloride, 20 deg C, 90 min
2: Et3N, MnO2 / CH2Cl2
3: 85 percent / trifluoroacetic acid / 1 h / 20 °C
4: 82 percent / chlorobenzene / 4 h / 131 °C
5: LiOH
View Scheme
(Z)-4-[(Z)-Benzyloxycarbonylimino]-2-(6-chloro-2-ethoxycarbonyl-4-hydroxy-5-oxo-5H-indol-7-yl)-pent-2-enedioic acid dimethyl ester

(Z)-4-[(Z)-Benzyloxycarbonylimino]-2-(6-chloro-2-ethoxycarbonyl-4-hydroxy-5-oxo-5H-indol-7-yl)-pent-2-enedioic acid dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 85 percent / trifluoroacetic acid / 1 h / 20 °C
2: 82 percent / chlorobenzene / 4 h / 131 °C
3: LiOH
View Scheme
2-Benzyloxycarbonylamino-4-(6-chloro-2-ethoxycarbonyl-4-hydroxy-5-oxo-5H-indol-7-yl)-pentanedioic acid dimethyl ester
98126-27-3, 98126-28-4

2-Benzyloxycarbonylamino-4-(6-chloro-2-ethoxycarbonyl-4-hydroxy-5-oxo-5H-indol-7-yl)-pentanedioic acid dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: Et3N, MnO2 / CH2Cl2
2: 85 percent / trifluoroacetic acid / 1 h / 20 °C
3: 82 percent / chlorobenzene / 4 h / 131 °C
4: LiOH
View Scheme
3-Amino-4,5-dihydroxy-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester
80721-45-5

3-Amino-4,5-dihydroxy-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 89 percent / concd. HCl, aq. NaNO2 / 0.33 h / 0 °C
2: HOAc, 50percent aq. H3PO2 / 1 h / Ambient temperature
3: 89 percent / aq. LiOH / tetrahydrofuran / 6.5 h
View Scheme
Multi-step reaction with 3 steps
1: NaNO2, concd HCl / 30 h / 0 °C
2: 1.) 50percent hypophosphorous acid, 2.) aq. basic potassium ferricyanide / 1.) acetic acid, 25 deg C, 20 min
3: 89 percent / LiOH / H2O; tetrahydrofuran / 6 h / 25 °C
View Scheme
3-Diazo-4,5-dioxo-4,5-dihydro-3H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester
80721-46-6

3-Diazo-4,5-dioxo-4,5-dihydro-3H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: HOAc, 50percent aq. H3PO2 / 1 h / Ambient temperature
2: 89 percent / aq. LiOH / tetrahydrofuran / 6.5 h
View Scheme
Multi-step reaction with 2 steps
1: 1.) 50percent hypophosphorous acid, 2.) aq. basic potassium ferricyanide / 1.) acetic acid, 25 deg C, 20 min
2: 89 percent / LiOH / H2O; tetrahydrofuran / 6 h / 25 °C
View Scheme
3-Nitro-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester
80721-44-4

3-Nitro-4,5-dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid 2-ethyl ester 7,9-dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: 98 percent / H2 / PtO2 / methanol / 3 h
2: 89 percent / concd. HCl, aq. NaNO2 / 0.33 h / 0 °C
3: HOAc, 50percent aq. H3PO2 / 1 h / Ambient temperature
4: 89 percent / aq. LiOH / tetrahydrofuran / 6.5 h
View Scheme
Multi-step reaction with 4 steps
1: 100 percent / H2 / 10percent Pd/C / methanol / 4 h / 760 Torr
2: NaNO2, concd HCl / 30 h / 0 °C
3: 1.) 50percent hypophosphorous acid, 2.) aq. basic potassium ferricyanide / 1.) acetic acid, 25 deg C, 20 min
4: 89 percent / LiOH / H2O; tetrahydrofuran / 6 h / 25 °C
View Scheme
trimethyl 4,5-dimethoxy-1H-pyrrolo<2,3-f>quinoline-2,7,9-tricarboxylate
78891-39-1

trimethyl 4,5-dimethoxy-1H-pyrrolo<2,3-f>quinoline-2,7,9-tricarboxylate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 60 percent / AgO, HNO3 / tetrahydrofuran / 0.17 h / Ambient temperature
2: 75 percent / LiOH, H2O / tetrahydrofuran / 5 h / Ambient temperature
View Scheme
Multi-step reaction with 2 steps
1: 66 percent / AgO, 6 N HNO3 / tetrahydrofuran / 0.17 h
2: 75 percent / H2O, LiOH / tetrahydrofuran / 5.5 h
View Scheme
dimethyl 7,8-dimethoxy-6-<3-methoxy-3-oxo-2-(phenylhydrazono)propyl>-5-nitro-2,4-quinolinedicarboxylate
78891-38-0

dimethyl 7,8-dimethoxy-6-<3-methoxy-3-oxo-2-(phenylhydrazono)propyl>-5-nitro-2,4-quinolinedicarboxylate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 62 percent / H2, HCl / 10percent Pd/C / methanol
2: 60 percent / AgO, HNO3 / tetrahydrofuran / 0.17 h / Ambient temperature
3: 75 percent / LiOH, H2O / tetrahydrofuran / 5 h / Ambient temperature
View Scheme
Multi-step reaction with 3 steps
1: 66 percent / H2, 5percent HCl / 5percent Pd/C / methanol / 2 h / Ambient temperature
2: 66 percent / AgO, 6 N HNO3 / tetrahydrofuran / 0.17 h
3: 75 percent / H2O, LiOH / tetrahydrofuran / 5.5 h
View Scheme
dimethyl 2-ketoglutarate
13192-04-6

dimethyl 2-ketoglutarate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1: Br2 / CH2Cl2 / Heating
2: Et3N / diethyl ether / 20 h / 25 °C
3: CH2Cl2 / 7 h / 25 °C
4: dry hydrogen chloride / CH2Cl2 / 10 h
5: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
6: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
7: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
3-bromo-2-oxopentane-1,5-dioic acid dimethyl ester
148728-48-7

3-bromo-2-oxopentane-1,5-dioic acid dimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: Et3N / diethyl ether / 20 h / 25 °C
2: CH2Cl2 / 7 h / 25 °C
3: dry hydrogen chloride / CH2Cl2 / 10 h
4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
5: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
6: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
6-Formylamino-5-methoxy-1H-indole-2-carboxylic acid methyl ester
78939-35-2

6-Formylamino-5-methoxy-1H-indole-2-carboxylic acid methyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 79 percent / hydrochloric acid / acetone; H2O / 1 h / Heating
2: CH2Cl2 / 7 h / 25 °C
3: dry hydrogen chloride / CH2Cl2 / 10 h
4: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
5: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
6: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
9-Hydroxy-5-methoxy-6,7,8,9-tetrahydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester
78939-38-5

9-Hydroxy-5-methoxy-6,7,8,9-tetrahydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: dry hydrogen chloride / CH2Cl2 / 10 h
2: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
3: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
4: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
Multi-step reaction with 3 steps
1: copper(II) acetate monohydrate; formic acid / 48 h / 25 °C
2: ammonium cerium (IV) nitrate / acetonitrile; water / 2 h / -5 °C
3: potassium carbonate / water / 12 h / 25 - 80 °C
View Scheme
6-amino-5-methoxy-2-methoxycarbonylindole
78939-36-3

6-amino-5-methoxy-2-methoxycarbonylindole

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: CH2Cl2 / 7 h / 25 °C
2: dry hydrogen chloride / CH2Cl2 / 10 h
3: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
4: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
5: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
Multi-step reaction with 4 steps
1: dichloromethane / 25 °C / Green chemistry; Industrial scale
2: copper(II) acetate monohydrate; formic acid / 25 °C / Green chemistry; Industrial scale
3: ammonium cerium (IV) nitrate / acetonitrile / -5 °C / Green chemistry; Industrial scale
4: potassium carbonate; water / water / 25 - 80 °C / Green chemistry; Industrial scale
View Scheme
Multi-step reaction with 4 steps
1: dichloromethane / 16 h / 25 °C
2: copper(II) acetate monohydrate; formic acid / 48 h / 25 °C
3: ammonium cerium (IV) nitrate / acetonitrile; water / 2 h / -5 °C
4: potassium carbonate / water / 12 h / 25 - 80 °C
View Scheme
5-methoxy-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester
78939-39-6

5-methoxy-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 60 percent / ceric ammonium nitrate / acetonitrile; H2O / 0.17 h / 0 °C
2: 92 percent / p-tuluenesulfonic acid / methanol / 4 h / Heating
3: 98 percent / 0.5 M K2CO3 / H2O / 4 h / 85 °C
View Scheme
Multi-step reaction with 2 steps
1: ammonium cerium (IV) nitrate / acetonitrile / -5 °C / Green chemistry; Industrial scale
2: potassium carbonate; water / water / 25 - 80 °C / Green chemistry; Industrial scale
View Scheme
Multi-step reaction with 2 steps
1: ammonium cerium (IV) nitrate / acetonitrile; water / 2 h / -5 °C
2: potassium carbonate / water / 12 h / 25 - 80 °C
View Scheme
methyl 4-(acetylamino)-o-anisate
4093-29-2

methyl 4-(acetylamino)-o-anisate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 9 steps
1: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
2: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature
3: 73 percent / NaOMe / methanol / 2 h / -15 °C
4: 87 percent / xylene / 4 h / Heating
5: 85 percent / HCl / methanol / 6 h / Heating
6: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether
7: 1.) BBr3; 2.) MeOH, H2SO4 (96percent) / 1.) CH2Cl2, room temp., 140 h; 2.) reflux, 48 h
8: 93 percent / benzoyl t-butyl nitroxide / methanol; CHCl3 / 16 h / Ambient temperature
View Scheme
Multi-step reaction with 10 steps
1: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
2: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature
3: 73 percent / NaOMe / methanol / 2 h / -15 °C
4: 87 percent / xylene / 4 h / Heating
5: 85 percent / HCl / methanol / 6 h / Heating
6: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether
7: 8.7 mg / NH4NO3 / trifluoroacetic acid / 3.75 h / Ambient temperature
8: 93 percent / H2 / 10percent palladium-on-charcoal / methanol / 20 h
9: 73 percent / MnO2 / aq. H2SO4 / 0.75 h / 0 °C
View Scheme
methyl 4-acetamido-2-hydroxybenzoate
4093-28-1

methyl 4-acetamido-2-hydroxybenzoate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

Conditions
ConditionsYield
Multi-step reaction with 10 steps
1: 97 percent / potassium carbonate / acetone / 8 h / Heating
2: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
3: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature
4: 73 percent / NaOMe / methanol / 2 h / -15 °C
5: 87 percent / xylene / 4 h / Heating
6: 85 percent / HCl / methanol / 6 h / Heating
7: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether
8: 1.) BBr3; 2.) MeOH, H2SO4 (96percent) / 1.) CH2Cl2, room temp., 140 h; 2.) reflux, 48 h
9: 93 percent / benzoyl t-butyl nitroxide / methanol; CHCl3 / 16 h / Ambient temperature
View Scheme
Multi-step reaction with 11 steps
1: 97 percent / potassium carbonate / acetone / 8 h / Heating
2: 98 percent / LiAlH4 / tetrahydrofuran / 2 h / 0 °C
3: 80 percent / manganese (IV) oxide / CHCl3; methanol / 20 h / Ambient temperature
4: 73 percent / NaOMe / methanol / 2 h / -15 °C
5: 87 percent / xylene / 4 h / Heating
6: 85 percent / HCl / methanol / 6 h / Heating
7: 2.) HCl / 1.) CH2Cl2, room temp., 12 h; 2.) 12 h, ether
8: 8.7 mg / NH4NO3 / trifluoroacetic acid / 3.75 h / Ambient temperature
9: 93 percent / H2 / 10percent palladium-on-charcoal / methanol / 20 h
10: 73 percent / MnO2 / aq. H2SO4 / 0.75 h / 0 °C
View Scheme
serin
302-84-1

serin

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

C15H7N3O7
132847-84-8

C15H7N3O7

Conditions
ConditionsYield
In water at 30℃; for 24h; pH = 9.7;100%
With air; cetyltrimethylammonim bromide at 30℃;55%
aminoguanidine sulfate
996-19-0

aminoguanidine sulfate

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid
79127-57-4

4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate for 24h;100%
at 30℃; Mechanism; pH 10;
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid
79127-57-4

4,5-dihydroxy-4,5-dioxo-1H-pyrrolo{2,3-f}quinoline-2,7,9-tricarboxylic acid

Conditions
ConditionsYield
With phenylhydrazine hydrochloride In methanol at 50℃; for 0.166667h;100%
With thiophenol In acetonitrile for 2h;84%
With acetate buffer; thiophenol In water; acetonitrile at 30℃;84 % Spectr.
With methylhydrazine In various solvent(s) at 30℃; Rate constant; anaerobic conditions;
With hydrogenchloride; ascorbic acid In water at 12 - 20℃; for 23h; pH=2.96;3.35 g
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

glycine
56-40-6

glycine

C15H7N3O7
132847-84-8

C15H7N3O7

Conditions
ConditionsYield
In water at 30℃; for 24h; pH = 6.6;100%
at 30℃; Rate constant; Mechanism; Product distribution; pH = 9.1; other pH values; other aminoacids;
With phosphate buffer pH 6.5; bovine serum In water Rate constant; Ambient temperature; pH range of 3.0 - 9.0;
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

1,2-diamino-benzene
95-54-5

1,2-diamino-benzene

3H-3,7,8,13-Tetraaza-benzo[a]cyclopenta[c]anthracene-2,4,6-tricarboxylic acid

3H-3,7,8,13-Tetraaza-benzo[a]cyclopenta[c]anthracene-2,4,6-tricarboxylic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide Ambient temperature;96%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

6,7-Dimethoxy-quinoxaline-2,3-diamine

6,7-Dimethoxy-quinoxaline-2,3-diamine

C24H14N6O8

C24H14N6O8

Conditions
ConditionsYield
In N,N-dimethyl-formamide Ambient temperature;95%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

dimethyl sulfate
77-78-1

dimethyl sulfate

trimethyl 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate
74447-88-4

trimethyl 4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; Schlenk technique; Inert atmosphere;91%
With potassium carbonate In N,N-dimethyl-formamide at 25℃; Inert atmosphere;57%
With potassium carbonate In N,N-dimethyl-formamide at 25℃;
With hydrogenchloride; potassium carbonate In water; N,N-dimethyl-formamide at 20 - 50℃; for 72.5h; Large scale;
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-1H-pyrrolo[2,3-f]chinoline-2,7,9-tricarboxylic acid trilithium salt

4,5-dihydroxy-1H-pyrrolo[2,3-f]chinoline-2,7,9-tricarboxylic acid trilithium salt

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 15 - 20℃; for 24h;90.5%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

trilithium pyrroloquinoline quinone

trilithium pyrroloquinoline quinone

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 15 - 20℃; for 24h;90.5%
With lithium hydroxide In water at 0 - 5℃; for 2h;10 mg
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

5-Diazo-4,5-dihydro-4-oxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure

5-Diazo-4,5-dihydro-4-oxo-1H-pyrrolo<2,3-f>chinolin-2,7,9-tricarbonsaeure

Conditions
ConditionsYield
With phosphate buffer; toluene-4-sulfonic acid hydrazide In tetrahydrofuran 1.) 2 h, 10 deg C, 2.) 3 h, room temperature;88%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid disodium salt

4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid disodium salt

Conditions
ConditionsYield
With sodium hydroxide at 25℃; for 3h; Reagent/catalyst;88%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

ethylenediamine
107-15-3

ethylenediamine

1H-1,4,7,8-Tetraaza-cyclopenta[l]phenanthrene-2,9,11-tricarboxylic acid

1H-1,4,7,8-Tetraaza-cyclopenta[l]phenanthrene-2,9,11-tricarboxylic acid

Conditions
ConditionsYield
With CTAB micellar system at 50℃; for 1h; Mechanism; further α,ω-diaminoalkanes;87%
With CTAB micellar system at 50℃; for 1h;87%
O-phospho-DL-serine
17885-08-4

O-phospho-DL-serine

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

C16H10N3O11P
144219-06-7

C16H10N3O11P

Conditions
ConditionsYield
In water at 30℃; for 24h; pH = 9.6;86%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-1H-pyrrolo[2,3-f]chinoline-2,7,9-tricarboxylic acid dilithium salt

4,5-dihydroxy-1H-pyrrolo[2,3-f]chinoline-2,7,9-tricarboxylic acid dilithium salt

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 15 - 20℃; for 24h;83.9%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-1H-pyrrolo[2,3-f]chinoline-2,7,9-tricarboxylic acid lithium salt

4,5-dihydroxy-1H-pyrrolo[2,3-f]chinoline-2,7,9-tricarboxylic acid lithium salt

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 15 - 20℃; for 24h;83.9%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-1H-pyrrole[2,3-f]chinoline-2,7,9-tricarboxylic acid, dilithium salt

4,5-dihydroxy-1H-pyrrole[2,3-f]chinoline-2,7,9-tricarboxylic acid, dilithium salt

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 15 - 20℃; for 24h;83.9%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

4,5-dihydroxy-1H-pyrrole[2,3-f]chinoline-2,7,9-tricarboxylic acid, lithium salt
1246998-46-8

4,5-dihydroxy-1H-pyrrole[2,3-f]chinoline-2,7,9-tricarboxylic acid, lithium salt

Conditions
ConditionsYield
With lithium hydroxide monohydrate In tetrahydrofuran; water at 15 - 20℃; for 24h;83.9%
betaine
107-43-7

betaine

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

C14H6N2O8*C5H11NO2

C14H6N2O8*C5H11NO2

Conditions
ConditionsYield
In ethanol at 25 - 30℃; for 24h;81%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

D,L-histidine
71-00-1

D,L-histidine

C19H11N5O7
144219-04-5

C19H11N5O7

Conditions
ConditionsYield
In water at 30℃; for 24h; pH = 6.7;80%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

2-Amino-1-phenylethanol
7568-93-6

2-Amino-1-phenylethanol

C15H7N3O7
132847-84-8

C15H7N3O7

Conditions
ConditionsYield
With cetyltrimethylammonim bromide In water at 30℃; for 24h; pH = 10.4;78%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

A

(4-hydroxyphenyl)methanol
623-05-2

(4-hydroxyphenyl)methanol

B

C15H7N3O7
132847-84-8

C15H7N3O7

Conditions
ConditionsYield
With air; cetyltrimethylammonim bromide at 30℃;A n/a
B 77%
Conditions
ConditionsYield
In water at 30℃; for 24h; carbonate buffer, pH = 10.0;77%
3-methoxy-2-aminopropionic acid
19794-53-7

3-methoxy-2-aminopropionic acid

pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

C17H11N3O8
144219-05-6

C17H11N3O8

Conditions
ConditionsYield
In water at 30℃; for 24h; pH = 9.8;72%
pyrroloquinoline quinone
72909-34-3

pyrroloquinoline quinone

C15H7N3O7
132847-84-8

C15H7N3O7

Conditions
ConditionsYield
In water at 30℃; for 24h; pH = 6.7;71%
Conditions
ConditionsYield
With air; cetyltrimethylammonim bromide at 30℃;70%
In water at 30℃; for 24h; pH = 10.2;70%
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