Overview Quick Details CAS No.: 623-05-2 Other Names: 4-Hydroxybenzyl Alcohol MF: C7H8O2 EINECS No.: 210-768-0 Place of Origin: Shandong, China (Mainland) Type: Pharmaceutical Intermediates Purity: 99.0%min Brand Name: Luyunjia Mode
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inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryProduct description: Product name 4-Hydroxybenzyl alcohol CAS number 623-05-2 Assay ≥99% Appearance White Crystalline Powder Capacity 200mt/year Application Organic synthesis
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inquiryUnique advantages for 4-Hydroxybenzyl alcohol Cas 623-05-2 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Powder Storage:2-8°C Package:25kg/drum or as you require A
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiryAs a leading and professional manufacturer of APIs and API intermediates in China,Anhui Dexinjia Biopharm Co., Ltd founded in 2006, Except for the R&D center, our company has built a close cooperation relation with Chinese Academy of Sciences,
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inquiry4-Hydroxybenzyl alcohol CAS 623-05-2 4-hydroxybenzenemethanol CAS no 623-05-2 4-(Hydroxymethyl)phenol 1-Naphthol Manufacturer High quality Best price In stock factory CAS 90-15-3 1-Naphthol COA TDS price MSDS highly quality and immedaite de
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inquiryAbout Product Details Mol File: 623
Cas:623-05-2
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inquiryWe are a professional chemicals, APIs and plant extract leading manufacturer in China. We are specialized in chemical synthesis, process development of pharmaceutical intermediates, active pharmaceutical ingredients (APIs), plant extract and rare c
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inquiryHigh quality 4-Hydroxybenzyl alcohol Cas 623-05-2 with factory favorable price Specifications: 623-05-2 4-Hydroxybenzyl alcohol High purity Fast deliver:Professional partner Item Specifications
Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationship
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inquiryAppearance:White or slightly yellow crystalline powder Storage:R.T Package:25kg/Barrel Application:Bisoprolol raw material intermediate Transportation:Express/Sea/Air Port:Any port in China
Cas:623-05-2
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Cas:623-05-2
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inquiry4-Hydroxybenzyl alcohol CAS: 623-05-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic in
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Cas:623-05-2
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Cas:623-05-2
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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Cas:623-05-2
Min.Order:1 Gram
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Appearance:Pink to beige Crystalline Powder Storage:Store below +30°C Application:4-Hydroxybenzyl alcohol is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. Po
Cas:623-05-2
Min.Order:25 Kilogram
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inquiryAdvantage 1: The product passed the professional production process and quality inspection, the purity is 99% +. 2: Highly qualified engineers to provide technical documents and service. 3: We could provide sample for your test. 4: High qualit
Cas:623-05-2
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Cas:623-05-2
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:623-05-2
Min.Order:1 Gram
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Conditions | Yield |
---|---|
With N-methylpyrrolidine zinc borohydride In tetrahydrofuran at 20℃; for 4h; | 100% |
With sodium tetrahydroborate In methanol at 0℃; | 100% |
With triethylamine; 2-hydroxyethanethiol In acetonitrile for 23h; Irradiation; | 100% |
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With water | 100% |
Conditions | Yield |
---|---|
With aniline; (ϖ-allyl)palladium triflate based catalyst at 30℃; for 0.333333h; | 99% |
With ammonium formate; palladium on activated charcoal In methanol for 0.5h; Heating; | 96% |
Conditions | Yield |
---|---|
With sodium tetrahydroborate; Trimethyl borate; dimethyl sulfate In tetrahydrofuran at 20℃; for 4.5h; Product distribution; Further Variations:; Reagents; reagent ratios; | 96% |
With [Zn(BH4)2(py)] In tetrahydrofuran for 3.6h; Heating; | 92% |
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 6h; Inert atmosphere; | 86% |
Conditions | Yield |
---|---|
With zirconium(IV) borohydride In tetrahydrofuran at 25℃; for 2h; Reduction; | 96% |
With zinc(II) tetrahydroborate; cyclohexene In tetrahydrofuran for 4h; Heating; | 72% |
With lithium aluminium tetrahydride In diethyl ether | |
With sodium tetrahydroborate In methanol; 1,2-dimethoxyethane for 1h; Reduction; Heating; |
1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With methanol; trimethylsilyl bromide at 20℃; for 5h; chemoselective reaction; | 96% |
With methanesulfonic acid In methanol at 20℃; for 1.33333h; | 94% |
sulfated SnO2 In methanol at 20℃; for 16h; | |
With trifluoroacetic acid In methanol at 25℃; for 0.333333h; Reagent/catalyst; |
p-hydroxymethylphenylboronic acid
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With urea hydrogen peroxide adduct In acetonitrile at 27 - 29℃; for 0.5h; Green chemistry; chemoselective reaction; | 95% |
With 1-carboxymethyl-3-methylimidazolium tetrachloroferrate; dihydrogen peroxide In neat (no solvent) at 20℃; for 0.133333h; | 91% |
With 1,3-dimethyl-5-ethyl-4a-hydroperoxyalloxazine; oxygen; hydrazine hydrate In methanol; 2,2,2-trifluoroethanol at 20℃; under 760.051 Torr; for 2h; | 74% |
4-trityloxymethyl-phenol
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With sodium hydrogen sulfate; silica gel In methanol; dichloromethane at 20℃; for 2h; | 93% |
4-(((tetrahydro-2H-pyran-2-yl)oxy)methyl)phenol
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
ruthenium trichloride In water; acetonitrile at 20℃; for 0.416667h; | 92% |
With lithium borohydride In methanol at 20℃; for 0.5h; | 90% |
With sulfuric acid; silica gel In methanol at 20℃; for 2.16667h; | 83% |
4-(trimethylsilyloxymethyl)phenoxytrimethylsilane
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With 1-butyl-3-methylimidazolium chloride at 20℃; for 12h; | 92% |
Conditions | Yield |
---|---|
With aluminum oxide In neat (no solvent) at 35℃; for 0.0166667h; microwave irradiation; | 89% |
1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
In water; N,N-dimethyl-formamide at 100℃; for 3h; | 88% |
[4-(2-trimethylsilanylethoxy)phenyl]methanol
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
Stage #1: [4-(2-trimethylsilanylethoxy)phenyl]methanol With cesium fluoride In N,N-dimethyl-formamide at 60℃; for 1h; Inert atmosphere; Stage #2: With water In N,N-dimethyl-formamide Inert atmosphere; | 88% |
(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methanol
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With sodium L-ascorbate; fluorescein free acid In aq. phosphate buffer for 0.5h; pH=7.4; Reagent/catalyst; Irradiation; | 88% |
(E)-6-(4-hydroxybenzyloxy)hex-3-en-2-one
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
Stage #1: (E)-6-(4-hydroxybenzyloxy)hex-3-en-2-one With sodium hydride In N,N-dimethyl-formamide at 22℃; for 1h; Stage #2: With hydrogenchloride In water; N,N-dimethyl-formamide | 87% |
4-iodo-benzyl alcohol
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With copper(l) iodide; triethanolamine; tetrabutylammomium bromide; water; potassium hydroxide at 120℃; for 24h; Inert atmosphere; | 86% |
With copper(l) iodide; triethanolamine; tetrabutylammomium bromide; potassium hydroxide In water at 120℃; for 24h; Inert atmosphere; Sealed tube; Green chemistry; | 86% |
With oxygen; triethylamine In acetonitrile at 32℃; for 24h; Schlenk technique; UV-irradiation; | 53% |
4-trimethylsilyloxymethylphenol
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With water In dichloromethane at 20℃; for 0.916667h; | 85% |
With Kaolinitic clay; water for 0.025h; Irradiation; microwave; | 82% |
4-(trimethylsilyloxymethyl)phenoxytrimethylsilane
A
(4-hydroxyphenyl)methanol
B
(4-Trimethylsilanyloxy-phenyl)-methanol
Conditions | Yield |
---|---|
With Dowex CCR-2 In ethanol for 10h; Ambient temperature; | A 19% B 82% |
With Dowex CCR-2 resin In ethanol for 10h; Product distribution; Ambient temperature; competitive desilylation with other TMS ethers, investigation; | A 19% B 82% |
(S)-1-((S)-2-tert-Butoxycarbonylamino-propionyl)-pyrrolidine-2-carboxylic acid 4-phenylacetoxy-benzyl ester
A
(4-hydroxyphenyl)methanol
B
N-tert-butoxycarbonyl-L-alanyl-L-proline
Conditions | Yield |
---|---|
With penicillin G acylase In methanol; phosphate buffer pH=7; Enzymatic reaction; | A n/a B 82% |
(S)-2-((2S,3R)-2-tert-Butoxycarbonylamino-3-hydroxy-butyrylamino)-3-phenyl-propionic acid 4-phenylacetoxy-benzyl ester
A
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With penicillin G acylase In methanol; phosphate buffer pH=7; Enzymatic reaction; | A n/a B 82% |
formaldehyd
phenol
A
(4-hydroxyphenyl)methanol
B
salicylic alcohol
Conditions | Yield |
---|---|
With sodium metaborate tetrahydrate In water at 60℃; Green chemistry; regioselective reaction; | A 10% B 80% |
With sodium hydroxide In water at 30℃; for 1h; Product distribution; other reagents, reagent concentrations, time and solvents; | |
With sodium hydroxide; HP-β-cyclodextrin In water at 4℃; for 240h; Product distribution; further additives; |
(S)-2-((S)-2-Allyloxycarbonylamino-3-methyl-butyrylamino)-propionic acid 4-phenylacetoxy-benzyl ester
A
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With penicillin G acylase In methanol; phosphate buffer pH=7; Enzymatic reaction; | A n/a B 80% |
(2S,3S)-2-((S)-2-tert-Butoxycarbonylamino-3-hydroxy-propionylamino)-3-methyl-pentanoic acid 4-phenylacetoxy-benzyl ester
A
(4-hydroxyphenyl)methanol
B
N-Boc-L-Ser-Ile-OH
Conditions | Yield |
---|---|
With penicillin G acylase In methanol; phosphate buffer pH=7; Enzymatic reaction; | A n/a B 80% |
Conditions | Yield |
---|---|
With 1-N-ferrocenylmethyl benzimidazole tagged polymer In N,N-dimethyl-formamide Reflux; | 79% |
With 1-butylpyridinium bromide for 0.05h; microwave irradiation; | 78% |
With [2Fe-2S] ferredoxin HaPux; CYP199A4 from the rhodopseudomonas palustrisstrain HaA2 (S244D); flavin-dependent ferredoxin reductase HaPuR; oxygen; NADH In aq. buffer pH=7.4; Catalytic behavior; Reagent/catalyst; regioselective reaction; |
L-Cysteine
A
aminoferrocene
B
(4-hydroxyphenyl)methanol
C
3-carboxy-5-oxoperhydro-1,4-thiazepine
Conditions | Yield |
---|---|
With 2-amino-4-mercaptobutyric acid; GLUTATHIONE Electrochemical reaction; | A n/a B n/a C 79% |
Conditions | Yield |
---|---|
With triethanolamine In water at 20℃; for 18h; Sonication; Irradiation; Green chemistry; | 78% |
Conditions | Yield |
---|---|
With air; cetyltrimethylammonim bromide at 30℃; | A n/a B 77% |
4-tert-butyl-butyldimethylsilyloxybenzyl alcohol THP ether
(4-hydroxyphenyl)methanol
Conditions | Yield |
---|---|
With iodine In methanol for 2h; desilylation; Heating; | 75% |
Conditions | Yield |
---|---|
With zinc(II) tetrahydroborate In tetrahydrofuran for 4h; Inert atmosphere; Reflux; | 70% |
With ethanol; potassium tert-butylate; C39H41FeMnN2O5P(1+)*Br(1-) In tert-butyl alcohol at 100℃; for 22h; Inert atmosphere; Schlenk technique; enantioselective reaction; | 10% |
With lithium aluminium tetrahydride; diethyl ether |
formaldehyd
phenol
A
4H-1,3,2-benzodioxin
B
(4-hydroxyphenyl)methanol
C
salicylic alcohol
Conditions | Yield |
---|---|
With hydrogenchloride; acetic acid at 65℃; for 20h; | A 3% B 68% C 7% |
Conditions | Yield |
---|---|
With Candida cylindracea lipase In hexane for 4h; | 100% |
novozyme 435 In acetonitrile at 20℃; for 6h; Enzymatic reaction; | 99% |
iodine at 20℃; for 2h; | 95% |
With porcine pancreatic lipase (PPL, Type II) In tetrahydrofuran at 42 - 45℃; for 48h; Acetylation; | 80% |
With Pseudomonas cepacia PS lipase In di-isopropyl ether at 25℃; for 0.5h; |
Conditions | Yield |
---|---|
With Oxone In ethanol at 20℃; for 2h; Catalytic behavior; | 100% |
With tert.-butylhydroperoxide; V/SiO2 In decane; tert-butyl alcohol at 25℃; for 3h; | 99.1% |
With titanium(IV) oxide; oxygen at 29.84℃; under 760.051 Torr; for 6h; Sealed tube; Irradiation; | 99% |
(4-hydroxyphenyl)methanol
tert-butyldimethylsilyl chloride
4-((tert-butyldimethylsilyloxy)methyl)phenol
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 0.75h; | 100% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1.5h; Cooling with ice; | 95% |
With sodium hydride In N,N-dimethyl-formamide | 95.6% |
2-nitropropane
(4-hydroxyphenyl)methanol
1-nitro-1,1-dimethyl-2-(4-hydroxyphenyl]ethane
Conditions | Yield |
---|---|
With potassium tert-butylate In diethylene glycol dimethyl ether at 20 - 137℃; for 6h; | 99.6% |
With potassium tert-butylate In diethylene glycol dimethyl ether Cooling with ice; Reflux; | 83% |
With tetrabutyl ammonium fluoride at 130℃; for 15h; | 73% |
(4-hydroxyphenyl)methanol
tert-butyldimethylsilyl chloride
1-(tert-butyldimethylsilyloxy)-4-((tert-butyldimethylsilyloxy)methyl)benzene
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 50℃; for 4h; | 99% |
With 1H-imidazole In N,N-dimethyl-formamide at 0 - 20℃; for 12h; Inert atmosphere; | 99% |
With 1H-imidazole In N,N-dimethyl-formamide Ambient temperature; | 97% |
(4-hydroxyphenyl)methanol
[4-(2-phenyl-quinolin-4-ylmethoxy)-phenyl]-methanol
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 20h; | 99% |
(4-hydroxyphenyl)methanol
[4-([1,3]thiazolo[4,5-b]pyridin-2-yloxy)phenyl]methanol
Conditions | Yield |
---|---|
Stage #1: 2-chloro[1,3]thiazolo[4,5-b]pyridine hydrochloride With potassium carbonate In acetonitrile at 50℃; for 3h; Inert atmosphere; Stage #2: (4-hydroxyphenyl)methanol In acetonitrile for 3h; Reflux; | 99% |
(4-hydroxyphenyl)methanol
benzyl alcohol
A
benzaldehyde
B
4-hydroxy-benzaldehyde
Conditions | Yield |
---|---|
With air; potassium carbonate at 20℃; for 12h; | A 99% B 11% |
Conditions | Yield |
---|---|
With palladium dichloride In methanol at 40℃; for 24h; Inert atmosphere; Green chemistry; chemoselective reaction; | A 99% B 99% |
Conditions | Yield |
---|---|
With 50wtpercent Cs2.5H0.5PW12O40 supported on MCM-41 In acetonitrile at 50℃; for 0.5h; | 98% |
With potassium fluoride at 80℃; for 7h; | 94% |
With potassium fluoride at 20℃; | 82% |
With sulfuric acid | |
In ethyl acetate at 30℃; for 8h; |
NH-pyrazole
(4-hydroxyphenyl)methanol
4-((1H-pyrazol-1-yl)methyl)phenol
Conditions | Yield |
---|---|
In water at 120℃; for 12h; Microwave irradiation; Sealed tube; | 98% |
at 160℃; for 0.5h; | 47% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone Heating; | 98% |
With potassium carbonate In acetone for 12h; Reflux; Inert atmosphere; | 91% |
With potassium carbonate; potassium iodide In acetone for 24h; Etherification; Heating; | 84% |
(4-hydroxyphenyl)methanol
propargyl bromide
(4-(prop-2-yn-1-yloxy)phenyl)methanol
Conditions | Yield |
---|---|
With potassium carbonate In toluene; acetonitrile at 70℃; for 20h; Inert atmosphere; | 98% |
With potassium carbonate In toluene; acetonitrile at 50℃; for 48h; | 95.5% |
Stage #1: (4-hydroxyphenyl)methanol With potassium carbonate In acetonitrile at 20℃; for 0.5h; Stage #2: propargyl bromide In toluene; acetonitrile at 50℃; for 40h; | 89% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 20h; Heating / reflux; | 98% |
With potassium carbonate In acetone Reflux; | 98% |
With potassium carbonate In acetone Heating; |
Conditions | Yield |
---|---|
With potassium carbonate In acetone Heating; | 98% |
(4-hydroxyphenyl)methanol
di-tert-butyl dicarbonate
tert-butyl (4-(hydroxymethyl)phenyl)carbonate
Conditions | Yield |
---|---|
With carbon tetrabromide at 65℃; for 0.75h; Neat (no solvent); chemoselective reaction; | 98% |
With 6,7-dimethoxyisoquinoline In dichloromethane at 20℃; for 10h; Inert atmosphere; chemoselective reaction; | 95% |
triphenylphosphine at 65℃; for 1h; | 85% |
(4-hydroxyphenyl)methanol
(R)-dimethyl 2-(3-(chloromethyl)benzamido)pentanedioate
(R)-dimethyl 2-(3-((4-(hydroxymethyl)phenoxy)methyl)benzamido)pentanedioate
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In acetonitrile at 70℃; for 5h; | 98% |
Conditions | Yield |
---|---|
With oxygen In acetonitrile at 20℃; for 7.5h; Catalytic behavior; | 97% |
With diethylene glycol dimethyl ether at 70℃; for 0.5h; Sonication; | 94% |
With tert.-butylhydroperoxide; ammonium cerium (IV) nitrate In water; acetonitrile at 20℃; for 24h; chemoselective reaction; | 90% |
2-Methylcyclopentane-1,3-dione
(4-hydroxyphenyl)methanol
2-(4-hydroxybenzyl)-2-methyl-1,3-cyclopentanedione
Conditions | Yield |
---|---|
In water at 80℃; for 12h; | 97% |
With water at 80℃; for 12h; Inert atmosphere; | 80% |
(4-hydroxyphenyl)methanol
1,1,1,3,3,3-hexamethyl-disilazane
4-trimethylsilyloxymethylphenol
Conditions | Yield |
---|---|
With silica-coated iron nanoparticles-supported RuIII (OTf)Salophen In dichloromethane at 20℃; for 0.0166667h; Catalytic behavior; | 97% |
With titanium(IV) dioxide In acetonitrile at 20℃; for 0.0833333h; chemoselective reaction; | 95% |
With nano Fe3O4 supported CeO2/SO4 2-bifunctional solid acidcatalyst In neat (no solvent) at 25℃; for 0.416667h; | 91% |
With poly(N-bromobenzene-1,3-disulfonamide) for 0.07h; Irradiation; | 90% |
With lithium perchlorate for 0.0166667h; Irradiation; microwave; | 68% |
(4-hydroxyphenyl)methanol
propionic acid anhydride
4-propionyloxybenzyl propionate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; | 97% |
(4-hydroxyphenyl)methanol
glutamic acid di-tert-butyl ester
Conditions | Yield |
---|---|
Stage #1: (4-hydroxyphenyl)methanol With phosgene; N-ethyl-N,N-diisopropylamine In dichloromethane; toluene; acetonitrile at 0℃; for 0.5h; Stage #2: glutamic acid di-tert-butyl ester With N-ethyl-N,N-diisopropylamine In dichloromethane; toluene; acetonitrile at 0℃; | 97% |
(4-hydroxyphenyl)methanol
triphenylphosphine hydrogen iodide
Conditions | Yield |
---|---|
In acetonitrile at 90℃; for 12h; | 97% |
Conditions | Yield |
---|---|
With nickel dichloride at 20℃; for 0.5h; Neat (no solvent); | 96% |
With dmap; triethylamine In dichloromethane for 2.5h; | 95% |
With iron zirconium phosphate In neat (no solvent) at 40℃; for 0.166667h; Green chemistry; | 92% |
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 4h; Heating; | 96% |
With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 6h; Inert atmosphere; | 93% |
With sodium hydride In N,N-dimethyl-formamide at 20℃; for 6h; | 90% |
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