Hangzhou Keying Chem Co., Ltd. Is a comprehensive enterprise, dedicated to the development, production and marketing of chemicals. As a technology innovative and service professional enterprise, Our company mainly engages in global pharmaceutical,
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inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Triumph has the complete production of G- KG - MT service chain,we can make the new technology into productivity quickly in the research and development of new products. Main Service 1.Own made fine chemical products 2.Out sourcing and quality c
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inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
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inquiryVapor Pressure:7.14mmHg at 25°C Refractive Index:1.409 Boiling Point:137.1 °C at 760 mmHg PKA:9.03±0.40(Predicted) Flash Point:41.3 °C PSA:21.26000 Density:0.891 g/cm3 LogP:0.32350 Storage Temp.:2-8°C(protect
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
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inquiry(R)-3-Methylmorpholine Basic information Product Name: (R)-3-Methylmorpholine Synonyms: (R)-3-Methylmorpholine;(R)-3-MethylmorpholineortheHClsalt;Morpholine, 3-Methyl-, (3R)-;Morpholine, 3-methyl-, (R)-;(R)-3-Methylmorpholine(WX900060);elagol
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inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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inquiryWe Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
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inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
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inquiryHigh quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:This product can be use
GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
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inquiryStock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
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inquiryLower price, sample is available,SDS test documents are available,large stock in warehouseAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:Fine chemical intermediates, used as the main raw material for the synthe
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea
Hunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
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inquiry★.Best quality according to requirement ★.Competitive price in China market ★.Mature Technical support ★.Professional logistic support
(R)-4-(4-methoxybenzyl)-3-methylmorpholine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With palladium on activated charcoal; hydrogen In methanol at 50℃; under 9500.64 Torr; for 18h; | 83% |
(5R)-5-methylmorpholin-3-one
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; for 16h; | 75% |
Stage #1: (5R)-5-methylmorpholin-3-one With lithium aluminium tetrahydride In tetrahydrofuran at 20℃; for 15.5h; Heating / reflux; Stage #2: With hydrogenchloride; ethanol In tetrahydrofuran |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Stage #1: (R)-2-(2-hydroxyethylamino)propan-1-ol With sulfuric acid at 140℃; for 14h; Stage #2: With sodium hydroxide In water at 0℃; | 65% |
2-(prop-2-yn-1-yloxy)ethan-1-amine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Stage #1: 2-(prop-2-yn-1-yloxy)ethan-1-amine With C42H58N4O2Ti In toluene at 110℃; for 14h; Inert atmosphere; Schlenk technique; Stage #2: With formic acid; [{(1S,2S-N-p-toluenesulfonyl-1,2-diphenylethanediamine)}(η6-p-cymene)RuCl]; triethylamine In N,N-dimethyl-formamide; toluene at 20℃; for 14h; Inert atmosphere; Schlenk technique; enantioselective reaction; | 65% |
Multi-step reaction with 2 steps 1: bis(N-2,6-diisoprpylphenylbenzamidato)bis(dimethylamido)titanium (IV) / toluene / 14 h / 110 °C / Inert atmosphere; Glovebox; Schlenk technique; Sealed tube 2: formic acid; [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); triethylamine / N,N-dimethyl-formamide / 23 °C / Inert atmosphere; Schlenk technique View Scheme | |
Multi-step reaction with 2 steps 1: bis(N-2,6-diisoprpylphenylbenzamidato)bis(dimethylamido)titanium (IV) / toluene / 14 h / 110 °C / Inert atmosphere; Glovebox; Schlenk technique; Sealed tube 2: formic acid; silver trifluoromethanesulfonate; [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); triethylamine / N,N-dimethyl-formamide / 16 h / 23 °C / Inert atmosphere; Schlenk technique View Scheme |
(3R)-3-methyl-4-(phenylmethyl)morpholine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal at 80℃; under 45600 - 60800 Torr; for 2h; | |
With hydrogen; palladium 10% on activated carbon In ethanol under 2585.81 Torr; | |
With hydrogen; hydrogenchloride; palladium 10% on activated carbon In 1,4-dioxane; ethyl acetate under 2068.65 Torr; for 18h; |
(R)-2-[Benzyl-(2-hydroxy-ethyl)-amino]-propan-1-ol
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 70percent H2SO4 / 15 h / 140 °C 2: H2 / 10percent Pd/C / 2 h / 80 °C / 45600 - 60800 Torr View Scheme |
(R)-2-bromo-N-(1-hydroxypropan-2-yl)-N-(4-methoxybenzyl)acetamide
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sodium hydride / tetrahydrofuran / 25 °C / Inert atmosphere 2: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Reflux 3: palladium on activated charcoal; hydrogen / methanol / 18 h / 50 °C / 9500.64 Torr View Scheme |
(R)-4-(4-methoxybenzyl)-5-methylmorpholin-3-one
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Reflux 2: palladium on activated charcoal; hydrogen / methanol / 18 h / 50 °C / 9500.64 Torr View Scheme |
Conditions | Yield |
---|---|
In dichloromethane at 23℃; Inert atmosphere; |
2-chloro-N-(2-hydroxy-1-methyl-ethyl)-acetamide
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: potassium tert-butylate / dichloromethane; isopropyl alcohol / 1 h / 0 - 20 °C 2: lithium aluminium tetrahydride / tetrahydrofuran / 16 h / 0 - 20 °C View Scheme |
Conditions | Yield |
---|---|
With [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); formic acid; silver trifluoromethanesulfonate; triethylamine In N,N-dimethyl-formamide at 23℃; for 16h; Inert atmosphere; Schlenk technique; enantioselective reaction; | A n/a B n/a |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); formic acid; triethylamine In N,N-dimethyl-formamide at 23℃; Reagent/catalyst; Inert atmosphere; Schlenk technique; enantioselective reaction; | n/a |
N-(tert-butyloxycarbonyl)-2-(propargyloxy)aminoethane
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: methanol / 0 - 23 °C 2: bis(N-2,6-diisoprpylphenylbenzamidato)bis(dimethylamido)titanium (IV) / toluene / 14 h / 110 °C / Inert atmosphere; Glovebox; Schlenk technique; Sealed tube 3: formic acid; [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); triethylamine / N,N-dimethyl-formamide / 23 °C / Inert atmosphere; Schlenk technique View Scheme | |
Multi-step reaction with 3 steps 1: methanol / 0 - 23 °C 2: bis(N-2,6-diisoprpylphenylbenzamidato)bis(dimethylamido)titanium (IV) / toluene / 14 h / 110 °C / Inert atmosphere; Glovebox; Schlenk technique; Sealed tube 3: formic acid; silver trifluoromethanesulfonate; [(1S,2S)-N-(p-toluensulfonyl)-1,2-diphenylethanediamine](p-cymene)ruthenium (I); triethylamine / N,N-dimethyl-formamide / 16 h / 23 °C / Inert atmosphere; Schlenk technique View Scheme |
4,6-Dichloro-2-(methylthio)pyrimidine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 40℃; for 16h; | 99% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at 40℃; | 68.1% |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
In ethanol Reflux; | 97% |
2-chloro-N-methyl-N-(6-(2-morphplino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-2-yl)acetamide
(3R)-3-methylmorpholine
N-methyl-2-[(3R)-3-methylmorpholin-4-yl]-N-[6-(2-morpholino-4-oxo-4H-chromen-8-yl)dibenzo[b,d]thiophen-2-yl]acetamide
Conditions | Yield |
---|---|
With triethylamine In dichloromethane; ISOPROPYLAMIDE at 60℃; for 2h; | 95% |
(1R,2R)-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)cyclopentanecarboxylic acid
(3R)-3-methylmorpholine
((1R,2R)-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)cyclopentyl)((R)-3-methylmorpholino)methanone
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 0 - 20℃; for 2h; | 95% |
(1R,2R)-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)-4-methoxycyclopentanecarboxylic acid
(3R)-3-methylmorpholine
((1R,2R)-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)-4-methoxycyclopentyl)((R)-3-methylmorpholino)methanone
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 2h; | 95% |
(3R)-3-methylmorpholine
acetyl chloride
1-[(3R)-3-methylmorpholin-4-yl]ethan-1-one
Conditions | Yield |
---|---|
Stage #1: (3R)-3-methylmorpholine With potassium carbonate In dichloromethane at 20℃; for 0.5h; Stage #2: acetyl chloride In dichloromethane at 20℃; for 18h; | 95% |
Stage #1: (3R)-3-methylmorpholine With potassium carbonate In dichloromethane at 0℃; for 0.5h; Stage #2: acetyl chloride In dichloromethane at 25℃; for 16h; | 88% |
Stage #1: (3R)-3-methylmorpholine With potassium carbonate In dichloromethane at 20℃; for 0.5h; Stage #2: acetyl chloride In dichloromethane at 20℃; for 18h; |
2,4-dichloro-6-piperidin-1-yl-[1,3,5]triazine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In 1,4-dioxane; dichloromethane at 20℃; | 95% |
(8S)-2-chloro-3-fluoro-8-(trifluoromethyl)-6,7,8,9-tetrahydro-4H-pyrimido[1,2-a]pyrimidin-4-one
(3R)-3-methylmorpholine
(2S)-7-fluoro-8-[(3R)-3-methylmorpholin-4-yl]-2-(trifluoromethyl)-1,2,3,4-tetrahydropyrimido[1,2-a]pyrimidin-6-one
Conditions | Yield |
---|---|
at 100℃; for 18h; | 91% |
2,6-Dichloro-4-morpholino-1,3,5-triazine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In ethanol at 0 - 20℃; Suzuki Coupling; | 91% |
With N-ethyl-N,N-diisopropylamine In ethanol at 0 - 20℃; | 91% |
With N-ethyl-N,N-diisopropylamine In ethanol at 0 - 20℃; | |
With N-ethyl-N,N-diisopropylamine |
1,3,5-trichloro-2,4,6-triazine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; | 91% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; | 91% |
In dichloromethane at 0 - 20℃; |
(3R)-3-methylmorpholine
2,4-dichloro-6-(4-nitrophenyl)-1,3,5-triazine
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In water; acetone at 0 - 20℃; for 20h; | 90% |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 100℃; for 18h; | 90% |
(3R)-3-methylmorpholine
6-bromo-4-chlorothieno[2,3-d]pyrimidine
Conditions | Yield |
---|---|
With triethylamine In 1,4-dioxane at 100℃; | 88% |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 1.5h; | 87.47% |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; | 87% |
2,6-dichloro-4-pyrimidinecarboxylic acid
(3R)-3-methylmorpholine
methyl 2-chloro-6-[(3R)-3-methylmorpholin-4-yl]pyrimidine-4-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 18h; | 86% |
(3R)-3-methylmorpholine
2,6-dichloropyrimidine-4-carboxylic acid methyl ester
methyl 2-chloro-6-[(3R)-3-methylmorpholin-4-yl]pyrimidine-4-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 20℃; for 18h; | 86% |
With triethylamine In dichloromethane at 20℃; for 18h; | 79.19% |
With triethylamine In dichloromethane at 20℃; for 16h; Temperature; | 70% |
With triethylamine In dichloromethane at 20℃; for 18h; Inert atmosphere; | 9% |
2,6-dichloro-3-nitropyridin-4-amine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl acetamide at 80℃; for 3h; | 86% |
Conditions | Yield |
---|---|
With bis(tri-tert-butylphasphine)palladium dichloride; potassium tert-butylate In toluene for 3h; Reflux; | 84% |
With copper(l) iodide; potassium carbonate; L-proline In dimethyl sulfoxide at 90℃; for 24h; | 5% |
(3R)-3-methylmorpholine
p-toluenesulfonyl chloride
(R)-3-methyl-4-tosylmorpholine
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; | 83% |
With triethylamine In dichloromethane at 0 - 23℃; |
(3R)-3-methylmorpholine
piperic acid
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 8h; | 83% |
(3R)-3-methylmorpholine
((1S,2S)-2-(5-(4-bromophenyl)-1H-imidazol-2-yl)cyclopentyl)((R)-3-methylmorpholino)methanone
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 2h; | 82% |
2,4,6-trichloropyrimidine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In ethanol at 65℃; for 12h; Cooling with ice; | 81.2% |
With triethylamine In ethanol at 20℃; for 16h; | 71% |
With triethylamine In ethanol at 20℃; for 16h; | 71% |
(3R)-3-methylmorpholine
(R)-4-(2-chloro-6-(methylsulfonylmethyl)pyrimidin-4-yl)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 18h; | 81% |
5,7-dichloro-[1,3]thiazolo[5,4-d]pyrimidine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 20℃; for 1.5h; Inert atmosphere; | 80% |
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
Stage #1: ethyl 2-(4-formylphenyl)thiazole-4-carboxylate; (3R)-3-methylmorpholine In dichloromethane at 20 - 30℃; for 0.5h; Inert atmosphere; Stage #2: With sodium tris(acetoxy)borohydride In dichloromethane at 30℃; for 16h; Cooling with ice; | 77.3% |
1,3,5-trichloro-2,4,6-triazine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at -50℃; for 2h; | 76% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at -50℃; for 2h; | 76% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at -50℃; for 10h; |
4,6-dichloro-5-nitropyrimidine
(3R)-3-methylmorpholine
Conditions | Yield |
---|---|
With triethylamine In tetrahydrofuran at 0℃; for 0.5h; | 75% |
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