1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:76470-66-1
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inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis according to the contract research and development services for the fine chemicals, ph
LF163892 MONOHYDRATE CAS:76470-66-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:76470-66-1
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
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inquiryEstablished in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site
Cas:76470-66-1
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung, LG, Merck, Thermo Fisher Scientific and so o
Cas:76470-66-1
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inquiryAppearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea
high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier
Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API
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inquiryAnsciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
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inquiry1-Azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid, 7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-chloro-8-oxo-, (6R,7S)-Appearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportati
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inquiryfactory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
BOC Sciences provides a wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.Appearanc
high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:Foil bag; Drum; Plastic bottle Application:Pharma;Industry;Agricultural Transportation:by sea or air Port:any port in China
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment terms accepted (Btc;MoneyGram;WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery (3-10 DAYS fast deli
Cas:76470-66-1
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inquiryFor quick quotation, please send us the inquiry include CAS#, Structure, Chemical Name, quantity, purity, as well as any additional specifications you require, we will try to get back to you within 24 hours. Our Services Besides manufacturing,
United Scientific Company Located in Shanghai of China , is a competitive player in the global specialty and fine chemical market. Fenghua has both the expertise and flexibility to produce a wide range of chemicals. Focusing on developing the innovat
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inquiryFINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the LF163892 MONOHYDRATE, CAS:76470-66-1 with the most competitive price and the best qua
Loracarbef 76470-66-1Appearance:solid or liquid Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma intermediate Transportation:By Sea,by Air,By courier like DHL or Fedx. Port:Shan
Impurities from EP, CP, USP, JP, IP and independent R&D Package:10mg, 25mg, 50mg, 100mg, Other scale please send an equiry Application:For research and development purpose Port:Guangzhou
Our company provides the best service for our customers. Under the premise of ensuring quality and delivery date, give customers the best price. The company is more willing to meet our customers. If you want to visit our factories and warehouses, we
high purity Application:Drug intermediates Materials intermediates and active molecules
(R)-Phenylglycine methyl ester
(6R*,7S*)-3-chloro-7-amino-8-oxo-1-azabicyclo<4.2.0>oct-2-en-2-carboxylic acid
loracarbef
Conditions | Yield |
---|---|
In water at 20℃; for 8.5h; Kluyvera citrophila KY-7844, phosphate buffer (pH 6.75); | 78.2% |
(6R,7S)-3-Chloro-7-[(R)-2-((E)-2-methoxycarbonyl-1-methyl-vinylamino)-2-phenyl-acetylamino]-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 4-nitro-benzyl ester
loracarbef
Conditions | Yield |
---|---|
Yield given. Multistep reaction; |
(6R,7S)-7-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 77.5 percent / piperazine / CHCl3 / 3 h 2: 1.) m-chloroperbenzoic acid, 2.) SO2Cl2 / 1.) CHCl3, 0 deg C, 30 min, 2.) CH2Cl2, 0 deg C, 1 h 3: 71.8 percent / trifluoroacetic acid / 1 h / 0 °C 4: hydrazine hydrate, 0.2N NaOH / 5 deg C, 3 h, 35 deg C 5: 78.2 percent / H2O / 8.5 h / 20 °C / Kluyvera citrophila KY-7844, phosphate buffer (pH 6.75) View Scheme |
tert-butyl (6R*,7S*)-3-chloro-7-amino-8-oxo-1-azabicyclo<4.2.0>oct-2-en-2-carboxylate
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 60.9 percent / CF3CO2H / 0.5 h / Ambient temperature 2: 78.2 percent / H2O / 8.5 h / 20 °C / Kluyvera citrophila KY-7844, phosphate buffer (pH 6.75) View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 68.4 percent / H2, 1N HCl / 10percent Pd-C / ethanol / 3 h / Ambient temperature 2: 60.9 percent / CF3CO2H / 0.5 h / Ambient temperature 3: 78.2 percent / H2O / 8.5 h / 20 °C / Kluyvera citrophila KY-7844, phosphate buffer (pH 6.75) View Scheme |
(6R*,7S*)-3-chloro-7-phenylacetamido-8-oxo-1-azabicyclo<4.2.0>oct-2-en-2-carboxylic acid
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 59 percent / H2O / 1.33 h / 40 °C / Kluyvera citrophila KY 7844 enzyme pH 8 2: 78.2 percent / H2O / 8.5 h / 20 °C / Kluyvera citrophila KY-7844, phosphate buffer (pH 6.75) View Scheme |
1-benzyl-3β-((S)-2-oxo-4-phenyloxazolidin-3-yl)-4β-[2-(2-furyl)ethyl]azetidin-2-one
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1: 1.) Li/NH3, t-BuOH 2.) aq. NaHCO3 / 1.) THF 2.) CH3CN 2: 77 percent / O3, H2O2 / CH2Cl2; methanol 3: carbonyl diimidazole / tetrahydrofuran 4: 85 percent / p-dodecyl-SO2N3, TEA / acetonitrile 5: 72 percent / Rh2(O2CC7H15)4 / CH2Cl2 6: 72 percent / (PhO)3PCl2, HCl / pyridine; CH2Cl2; ethyl acetate; various solvent(s) 7: 1.) TEA 2.) TEA, i-BuOCOCl / 2.) DMBA / 1.) ETOH, H2O 2.) DMF View Scheme |
p-nitrobenzyl 7β-[(phenoxyacetyl)amino]-3-hydroxy-1-carba-1-dethia-3-cephem-4-carboxylate
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 72 percent / (PhO)3PCl2, HCl / pyridine; CH2Cl2; ethyl acetate; various solvent(s) 2: 1.) TEA 2.) TEA, i-BuOCOCl / 2.) DMBA / 1.) ETOH, H2O 2.) DMF View Scheme |
3-[((R)-carboxy-phenyl-methyl)-amino]-but-2-enoic acid methyl ester
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 1.) TEA 2.) TEA, i-BuOCOCl / 2.) DMBA / 1.) ETOH, H2O 2.) DMF View Scheme |
cis-4-oxo-3-[(phenoxyacetyl)amino]-2-azetidinepropanoic acid
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1: carbonyl diimidazole / tetrahydrofuran 2: 85 percent / p-dodecyl-SO2N3, TEA / acetonitrile 3: 72 percent / Rh2(O2CC7H15)4 / CH2Cl2 4: 72 percent / (PhO)3PCl2, HCl / pyridine; CH2Cl2; ethyl acetate; various solvent(s) 5: 1.) TEA 2.) TEA, i-BuOCOCl / 2.) DMBA / 1.) ETOH, H2O 2.) DMF View Scheme |
cis-α-diazo-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid, (4-nitrophenyl)methyl ester
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 72 percent / Rh2(O2CC7H15)4 / CH2Cl2 2: 72 percent / (PhO)3PCl2, HCl / pyridine; CH2Cl2; ethyl acetate; various solvent(s) 3: 1.) TEA 2.) TEA, i-BuOCOCl / 2.) DMBA / 1.) ETOH, H2O 2.) DMF View Scheme |
cis-β,4-dioxo-3-[(phenoxyacetyl)amino]-2-azetidinepentanoic acid, (4-nitrophenyl)methyl ester
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: 85 percent / p-dodecyl-SO2N3, TEA / acetonitrile 2: 72 percent / Rh2(O2CC7H15)4 / CH2Cl2 3: 72 percent / (PhO)3PCl2, HCl / pyridine; CH2Cl2; ethyl acetate; various solvent(s) 4: 1.) TEA 2.) TEA, i-BuOCOCl / 2.) DMBA / 1.) ETOH, H2O 2.) DMF View Scheme |
loracarbef
Conditions | Yield |
---|---|
Stage #1: mono N,N-DMAc solvate of loracarbef With hydrogenchloride; pyrographite In water for 0.5 - 0.666667h; Stage #2: With ammonia In water at 50 - 55℃; for 1h; pH=1.8 - 1.9; |
loracarbef
Conditions | Yield |
---|---|
Stage #1: mono N-methylpyrrolidone solvate of loracarbef With hydrogenchloride; pyrographite In water for 0.5 - 0.666667h; Stage #2: With ammonia In water at 50 - 55℃; for 1 - 1.08333h; pH=1.8 - 4.8; |
loracarbef
phenyl isothiocyanate
(6R,7S)-3-chloro-8-oxo-7-((R)-2-phenyl-2-(3-phenylthioureido)acetamido)-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
Conditions | Yield |
---|---|
With triethylamine In N,N-dimethyl-formamide for 24h; | 96% |
loracarbef
3-methylbenzene-1,2-diol
3-chloro-7-[2-(5-methyl-3,4-dioxocyclohexa-1,5-dienylamino)-2-phenylacetylamino]-8-oxo-5-azabicyclo[4.2.0]oct-3-ene-4-carboxylic acid
Conditions | Yield |
---|---|
With oxygen at 20℃; for 1.5h; pH=5.6; aq. acetate buffer; Enzymatic reaction; | 81% |
2,5-dihydroxy-N-(2-hydroxyethyl)benzamide
loracarbef
Conditions | Yield |
---|---|
With air; sodium acetate buffer at 20℃; for 3h; pH=5.6; | 77% |
2,5-dioxopyrrolidin-1-yl 6-(tritylthio)hexanoate
loracarbef
C41H40ClN3O5S
Conditions | Yield |
---|---|
With pyridine In tetrahydrofuran; water; N,N-dimethyl-formamide at 22℃; for 3h; Inert atmosphere; | 56% |
loracarbef
{(2,3-diacetoxy-benzoyl)-[4-(2,3-diacetoxy-benzoylamino)-butyl]-amino}-acetic acid
Conditions | Yield |
---|---|
Stage #1: {(2,3-diacetoxy-benzoyl)-[4-(2,3-diacetoxy-benzoylamino)-butyl]-amino}-acetic acid With 1-hydroxy-pyrrolidine-2,5-dione; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride Stage #2: loracarbef With sodium hydrogencarbonate | 41% |
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In tetrahydrofuran; water at 20℃; for 1h; | 22% |
Conditions | Yield |
---|---|
In water for 1800h; Product distribution; Mechanism; Ambient temperature; further times and temp., also with H2O2, O2 or buffer; degradation pathway; |
loracarbef
isobutene
(6R,7S)-7-((R)-2-Amino-2-phenyl-acetylamino)-3-chloro-8-oxo-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With sulfuric acid In 1,4-dioxane |
loracarbef
Allyl chloroformate
Conditions | Yield |
---|---|
With pH 8.5 In water; acetone |
gentisamide
loracarbef
Conditions | Yield |
---|---|
With air; sodium acetate buffer at 20℃; for 3h; pH=5.6; |
Methyl 2,5-dihydroxybenzoate
loracarbef
Conditions | Yield |
---|---|
With air; sodium acetate buffer at 20℃; for 3h; pH=5.6; |
ethyl 2,5-dihydroxybenzoate
loracarbef
Conditions | Yield |
---|---|
With air; sodium acetate buffer at 20℃; for 3h; pH=5.6; |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2SO4 / dioxane 2: dimethylformamide 3: TFA / CH2Cl2 View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2SO4 / dioxane 2: dimethylformamide View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2SO4 / dioxane 2: dimethylformamide 3: TFA / CH2Cl2 View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2SO4 / dioxane 2: dimethylformamide 3: TFA / CH2Cl2 View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2SO4 / dioxane 2: dimethylformamide 3: TFA / CH2Cl2 View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2SO4 / dioxane 2: dimethylformamide View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: pH 8.5 / H2O; acetone 2: Na2CO3 / dimethylformamide 3: dimethylformamide 4: Pd(PPh3)4, sodium 2-ethylhexanoate View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: H2SO4 / dioxane 2: dimethylformamide View Scheme |
loracarbef
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2SO4 / dioxane 2: dimethylformamide 3: TFA / CH2Cl2 View Scheme |
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