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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

2,5-Pyrrolidinedione,3-ethyl-3-methyl-

Cas:77-67-8

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

ethosuximide manufacturer/supplier

Cas:77-67-8

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Ethosuximide

Cas:77-67-8

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

77-67-8 ETHOSUXIMIDE

Cas:77-67-8

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Discount price CAS 77-67-8 with best quality

Cas:77-67-8

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,5-Pyrrolidinedione,3-ethyl-3-methyl- 77-67-8

Cas:77-67-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. A

ETHOSUXIMIDE Antiepileptic and anticonvulsant drugs

Cas:77-67-8

Min.Order:1 Kilogram

FOB Price: $200.0 / 300.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

ETHOSUXIMIDE CAS:77-67-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates,

ETHOSUXIMIDE CAS:77-67-8

Cas:77-67-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,5-Pyrrolidinedione,3-ethyl-3-methyl-

Cas:77-67-8

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:1 Kilogram

FOB Price: $80.0 / 100.0

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Ethosuximide

Cas:77-67-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,5-Pyrrolidinedione,3-ethyl-3-methyl-

Cas:77-67-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

2,5-Pyrrolidinedione,3-ethyl-3-methyl-

Cas:77-67-8

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

ETHOSUXIMIDE Basic information Product Name: ETHOSUXIMIDE Synonyms: Succinimide, 2-ethyl-2-methyl- (6CI, 7CI, 8CI);α-Ethyl-α-methylsuccinimide;α-Methyl-α-ethylsuccinimide;3-ethyl-3-methy

77-67-8 ETHOSUXIMIDE C7H11NO2

Cas:77-67-8

Min.Order:1 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

EthosuxiMide, USP

Cas:77-67-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:1 Metric Ton

FOB Price: $1.5

Type:Trading Company

inquiry

SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

Ethosuximide

Cas:77-67-8

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Bluecrystal chem-union

We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

ethosuximide

Cas:77-67-8

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Ethosuximide

Cas:77-67-8

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY:1) Specialized in pharmaceutical and healthcare industrial since 19872) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days.4) We have warehouse in USA with quickly shipment . Application:API

99% up by HPLC ETHOSUXIMIDE 77-67-8

Cas:77-67-8

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Dingyan Chem Co., Ltd

R & D enterprises have their own stock in stock Package:1kg Application:pharmaceutical intermediates

2,5-Pyrrolidinedione,3-ethyl-3-methyl-

Cas:77-67-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

Ethosuximide (500 mg)

Cas:77-67-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

ETHOSUXIMIDE

Cas:77-67-8

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

C14H17NO3

C14H17NO3

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Stage #1: C14H17NO3 With palladium on activated charcoal; hydrogen
Stage #2: With triethylamine; α-bromoacetophenone
83%
4-ethyl-1-(4-methoxybenzyl)-4-methylpyrrolidine-2,5-dione
166324-36-3

4-ethyl-1-(4-methoxybenzyl)-4-methylpyrrolidine-2,5-dione

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
With ammonium cerium(IV) nitrate In water; acetonitrile for 1h; Ambient temperature;47%
2-ethyl-2-methylsuccinic acid
631-31-2

2-ethyl-2-methylsuccinic acid

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
With ammonia
With ammonium hydroxide at 200℃;
With ammonium hydroxide In water at 190℃; for 1.5h;
ammonium salt of/the/ α-methyl-α-ethyl-succinic acid

ammonium salt of/the/ α-methyl-α-ethyl-succinic acid

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
durch Destillation;
2-Methylbutyraldehyde
96-17-3, 57456-98-1

2-Methylbutyraldehyde

Ag2O

Ag2O

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1: 1.) MgSO4, 2.) N,N-diethylaniline / 1.) Et2O, 2 h, RT, 2.) toluene, -78 deg C to RT, 24 h
2: N-chlorosuccinimide / 40 deg C, 2 h; 80 deg C, 1 h
3: SiO2, H2O / 1.) 35 deg C, overnight then 60 deg C, 30 min, 2.) benzene, 1 h
4: 58 percent / Raney nickel (W-2) / ethanol / 3 h / Heating
5: 56 percent / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature
6: 47 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
View Scheme
4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methylpyrrolidin-2-one
166324-35-2

4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methylpyrrolidin-2-one

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 56 percent / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature
2: 47 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
View Scheme
4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one
166324-34-1

4-ethyl-5-hydroxy-1-(4-methoxybenzyl)-4-methyl-3-(methylthio)pyrrolidin-2-one

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: 58 percent / Raney nickel (W-2) / ethanol / 3 h / Heating
2: 56 percent / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature
3: 47 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
View Scheme
N-(2-methylbut-1-enyl)-N-(4-methoxybenzyl)-α-(methylthio)acetamide

N-(2-methylbut-1-enyl)-N-(4-methoxybenzyl)-α-(methylthio)acetamide

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1: N-chlorosuccinimide / 40 deg C, 2 h; 80 deg C, 1 h
2: SiO2, H2O / 1.) 35 deg C, overnight then 60 deg C, 30 min, 2.) benzene, 1 h
3: 58 percent / Raney nickel (W-2) / ethanol / 3 h / Heating
4: 56 percent / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature
5: 47 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
View Scheme
2-Chloro-N-(4-methoxy-benzyl)-N-((E)-2-methyl-but-1-enyl)-2-methylsulfanyl-acetamide
1027595-29-4

2-Chloro-N-(4-methoxy-benzyl)-N-((E)-2-methyl-but-1-enyl)-2-methylsulfanyl-acetamide

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1: SiO2, H2O / 1.) 35 deg C, overnight then 60 deg C, 30 min, 2.) benzene, 1 h
2: 58 percent / Raney nickel (W-2) / ethanol / 3 h / Heating
3: 56 percent / pyridinium chlorochromate / CH2Cl2 / 2 h / Ambient temperature
4: 47 percent / cerium(IV) ammonium nitrate / acetonitrile; H2O / 1 h / Ambient temperature
View Scheme
C15H21NO2

C15H21NO2

ethosuximide
77-67-8

ethosuximide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: copper (I) acetate; Bathocuproine; oxygen / toluene / 80 °C / 760.05 Torr
2: hydrogen; palladium on activated charcoal
View Scheme
morpholine
110-91-8

morpholine

ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

3-methyl-3-ethyl-1-(morpholin-4-ylmethyl)-pyrrolidine-2,5-dione
3780-75-4

3-methyl-3-ethyl-1-(morpholin-4-ylmethyl)-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;94%
In ethanol at 20℃; for 12h;82%
piperidine
110-89-4

piperidine

ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

3-methyl-3-ethyl-1-(piperidin-1-ylmethyl)-pyrrolidine-2,5-dione
3780-73-2

3-methyl-3-ethyl-1-(piperidin-1-ylmethyl)-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;94%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-(2-pyridinyl)piperazine
20980-22-7

N-(2-pyridinyl)piperazine

C16H23N5O2
1402547-04-9

C16H23N5O2

Conditions
ConditionsYield
In ethanol at 20℃; for 12h;88%
1-methyl-piperazine
109-01-3

1-methyl-piperazine

ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-[(4-methyl-piperazin-1-yl)methyl]-3-ethyl-3-methylpyrrolidine-2,5-dione dihydrochloride

N-[(4-methyl-piperazin-1-yl)methyl]-3-ethyl-3-methylpyrrolidine-2,5-dione dihydrochloride

Conditions
ConditionsYield
Stage #1: 1-methyl-piperazine; ethosuximide; formaldehyd In ethanol at 20℃; for 12h;
Stage #2: With hydrogenchloride In ethanol
86%
cyclohexylpiperazine
17766-28-8

cyclohexylpiperazine

ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

C18H31N3O2
1402547-06-1

C18H31N3O2

Conditions
ConditionsYield
In ethanol at 20℃; for 12h;81%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(o-fluorophenyl)piperazine
1011-15-0

1-(o-fluorophenyl)piperazine

N-[{4-(2-fluorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

N-[{4-(2-fluorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

Conditions
ConditionsYield
Stage #1: ethosuximide; formaldehyd; 1-(o-fluorophenyl)piperazine In ethanol; water at 20℃;
Stage #2: With hydrogenchloride In ethanol
78%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-(m-chlorophenyl)piperazine
6640-24-0

N-(m-chlorophenyl)piperazine

N-[{4-(3-chlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
1429300-89-9

N-[{4-(3-chlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;78%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

4-Aminoacetophenone
99-92-3

4-Aminoacetophenone

1-{[(4-acetylphenyl)amino]methyl}-3-methyl-3-ethylpyrrolidine-2,5-dione

1-{[(4-acetylphenyl)amino]methyl}-3-methyl-3-ethylpyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;78%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

diethylamine
109-89-7

diethylamine

1-[(diethylamino)methyl]-3-methyl-3-ethylpyrrolidine-2,5-dione

1-[(diethylamino)methyl]-3-methyl-3-ethylpyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;77%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(3,4-dichloro)phenylpiperazine
57260-67-0

1-(3,4-dichloro)phenylpiperazine

N-[{4-(3,4-dichlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
1429300-90-2

N-[{4-(3,4-dichlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;75%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(3-Methylphenyl)piperazine
41186-03-2

1-(3-Methylphenyl)piperazine

N-[{4-(3-methylphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
1429300-93-5

N-[{4-(3-methylphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;72%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

p-toluidine
106-49-0

p-toluidine

3-methyl-3-ethyl-1-{[(4-methylphenyl)amino]methyl}pyrrolidine-2,5-dione
31881-69-3

3-methyl-3-ethyl-1-{[(4-methylphenyl)amino]methyl}pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;72%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

4-phenyl-1-piperazine
92-54-6

4-phenyl-1-piperazine

N-[(4-phenyl-piperazin-1-yl)-methyl]-3-ethyl-3-methylpyrrolidine-2,5-dione
17330-65-3

N-[(4-phenyl-piperazin-1-yl)-methyl]-3-ethyl-3-methylpyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;70%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

4-amino-benzoic acid
150-13-0

4-amino-benzoic acid

4-{[(3-methyl-3-ethyl-2,5-dioxopyrrolidin-1-yl)-methyl]amino}benzoic acid

4-{[(3-methyl-3-ethyl-2,5-dioxopyrrolidin-1-yl)-methyl]amino}benzoic acid

Conditions
ConditionsYield
In ethanol at 70 - 80℃;70%
1-(2-hydroxyethyl)piperazine
103-76-4

1-(2-hydroxyethyl)piperazine

ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-ethyl-3-methylpyrrolidine-2,5-dione dihydrochloride

N-{[4-(2-hydroxyethyl)piperazin-1-yl]methyl}-3-ethyl-3-methylpyrrolidine-2,5-dione dihydrochloride

Conditions
ConditionsYield
Stage #1: 1-(2-hydroxyethyl)piperazine; ethosuximide; formaldehyd In ethanol at 20℃; for 12h;
Stage #2: With hydrogenchloride In ethanol
68%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

4-(4-chlorophenyl) piperazine
38212-33-8

4-(4-chlorophenyl) piperazine

N-[{4-(4-chlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
19027-43-1

N-[{4-(4-chlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;68%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

4-benzylpyperidine
31252-42-3

4-benzylpyperidine

C20H28N2O2
1402547-08-3

C20H28N2O2

Conditions
ConditionsYield
In ethanol at 20℃; for 12h;67%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(2-Methoxyphenyl)piperazine
35386-24-4

1-(2-Methoxyphenyl)piperazine

N-[{4-(2-methoxyphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

N-[{4-(2-methoxyphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

Conditions
ConditionsYield
Stage #1: ethosuximide; formaldehyd; 1-(2-Methoxyphenyl)piperazine In ethanol; water at 20℃;
Stage #2: With hydrogenchloride In ethanol
66%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

4-(3-methoxyphenyl)piperazine
16015-71-7

4-(3-methoxyphenyl)piperazine

N-[{4-(3-methoxyphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
1429300-95-7

N-[{4-(3-methoxyphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;65%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(o-toluyl)piperazine
39512-51-1

1-(o-toluyl)piperazine

N-[{4-(2-methylphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
1429300-92-4

N-[{4-(2-methylphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;64%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-phenylmethylpiperazine
2759-28-6

1-phenylmethylpiperazine

C19H27N3O2*ClH

C19H27N3O2*ClH

Conditions
ConditionsYield
Stage #1: ethosuximide; formaldehyd; 1-phenylmethylpiperazine In ethanol at 20℃; for 12h;
Stage #2: With hydrogenchloride In ethanol
62%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(3-Trifluoromethylphenyl)piperazine
15532-75-9

1-(3-Trifluoromethylphenyl)piperazine

N-[{4-(3-trifluoromethylphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione
1429300-91-3

N-[{4-(3-trifluoromethylphenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol; water at 20℃;61%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

1-(4-Fluorophenyl)piperazine
2252-63-3

1-(4-Fluorophenyl)piperazine

N-[{4-(4-fluorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

N-[{4-(4-fluorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

Conditions
ConditionsYield
Stage #1: ethosuximide; formaldehyd; 1-(4-Fluorophenyl)piperazine In ethanol; water at 20℃;
Stage #2: With hydrogenchloride In ethanol
58%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-(o-Chlorophenyl)piperazine
39512-50-0

N-(o-Chlorophenyl)piperazine

N-[{4-(2-chlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

N-[{4-(2-chlorophenyl)-piperazin-1-yl}-methyl]-3-ethyl-3-methyl-pyrrolidine-2,5-dione monohydrochloride

Conditions
ConditionsYield
Stage #1: ethosuximide; formaldehyd; N-(o-Chlorophenyl)piperazine In ethanol; water at 20℃;
Stage #2: With hydrogenchloride In ethanol
58%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

[4-(propan-2-yloxy)phenyl]methanamine
21244-34-8

[4-(propan-2-yloxy)phenyl]methanamine

1-{[(4-isopropoxybenzyl)amino]methyl}-3-methyl-3-ethylpyrrolidine-2,5-dione

1-{[(4-isopropoxybenzyl)amino]methyl}-3-methyl-3-ethylpyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;53%
ethosuximide
77-67-8

ethosuximide

CpFe(CO)2[η(1)-N(1)-4-iodoacetamidophthalimidato]
211931-52-1

CpFe(CO)2[η(1)-N(1)-4-iodoacetamidophthalimidato]

(C5H5)Fe(CO)2(C8H3NO2NHC(O)CH2C4H2NO2(CH3)C2H5)
211931-54-3

(C5H5)Fe(CO)2(C8H3NO2NHC(O)CH2C4H2NO2(CH3)C2H5)

Conditions
ConditionsYield
With sodium methylate In methanol Ar-atmosphere; 50°C (2 d); H2O addn. (room temp.), extg. (CH2Cl2), drying (Na2SO4), evapn., ether addn., pptn. on hexane addn. and concg.; elem .anal.;51%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-ethylbutylamine
13360-63-9

N-ethylbutylamine

1-{[butyl(ethyl)amino]methyl}-3-methyl-3-ethylpyrrolidine-2,5-dione

1-{[butyl(ethyl)amino]methyl}-3-methyl-3-ethylpyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;48%
ethosuximide
77-67-8

ethosuximide

formaldehyd
50-00-0

formaldehyd

N-cyclohexyl-cyclohexanamine
101-83-7

N-cyclohexyl-cyclohexanamine

1-[(dicyclohexylamino)methyl]-3-methyl-3-ethylpyrrolidine-2,5-dione

1-[(dicyclohexylamino)methyl]-3-methyl-3-ethylpyrrolidine-2,5-dione

Conditions
ConditionsYield
In ethanol at 70 - 80℃;48%

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