DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:775304-57-9
Min.Order:1 Metric Ton
FOB Price: $1.0 / 3.0
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:775304-57-9
Min.Order:1 Gram
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Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva
Cas:775304-57-9
Min.Order:1 Gram
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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Min.Order:1 Kilogram
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inquiryAppearance:White powder Storage:room temperature Package:25kg/drum Application:APIs Transportation:Express/Sea/Air Port:any port in china
Cas:775304-57-9
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
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Min.Order:1 Kilogram
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present,
Ataluren (PTC124)CAS:775304-57-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic interme
Cas:775304-57-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
API name: Ataluren Certificates: GMP, DMF CAS No.: 775304-57-9 Chemical name: 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoic acid Ataluren Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]- PTC124 Formula: C15H9FN2O
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:775304-57-9
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
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inquiryFactory direct sales, accept customization. PTC-124 is a nonaminoglycoside that has been reported to induce ribosomes to read through premature nonsense stop signals on mRNA, allowing the production of full-length functional proteins. Kind Pharma h
We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to provide excellence in researching, manufacturing and drug discovery process. Our research team of sci
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:775304-57-9
Min.Order:0 Metric Ton
Negotiable
Type:Other
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Cas:775304-57-9
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:775304-57-9
Min.Order:10 Gram
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Type:Lab/Research institutions
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Min.Order:1 Milligram
Negotiable
Type:Trading Company
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
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Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryHunan chemfish Pharmaceutical co.,Ltd.located in Lugu High-tech industral park ,Hunan province . with its own R&D center and more than 10000㎡manufacture plant . Chemfish owns 40 reactors from 1000L to 8000L. With complete auxiliary equipment as
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Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryZhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed
Cas:775304-57-9
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:775304-57-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:775304-57-9
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryGOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation
We are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
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Type:Trading Company
inquiry3-((5-(2-fluorophenyl))-(1,2,4-oxadiazol-3-yl))benzoic acid methyl ester
Conditions | Yield |
---|---|
Stage #1: 3-((5-(2-fluorophenyl))-(1,2,4-oxadiazol-3-yl))benzoic acid methyl ester With sodium hydroxide; water at 100℃; for 2h; Heating / reflux; Stage #2: With hydrogenchloride In water | 96% |
Stage #1: 3-((5-(2-fluorophenyl))-(1,2,4-oxadiazol-3-yl))benzoic acid methyl ester With sodium hydroxide; water In tetrahydrofuran at 100℃; for 2h; Heating / reflux; Stage #2: With hydrogenchloride In water | 96% |
Stage #1: 3-((5-(2-fluorophenyl))-(1,2,4-oxadiazol-3-yl))benzoic acid methyl ester With sodium hydroxide; water In tetrahydrofuran at 100℃; for 2h; Heating / reflux; Stage #2: With hydrogenchloride In water | 96% |
Conditions | Yield |
---|---|
Stage #1: 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzaldehyde With potassium dihydrogenphosphate; dihydrogen peroxide In water; acetonitrile at 20 - 30℃; Stage #2: With sodium chlorite In water; acetonitrile at 0 - 30℃; for 5h; | 90% |
ataluren
Conditions | Yield |
---|---|
In tert-butyl alcohol at 80℃; for 24h; | 88.4% |
5-(2-fluorophenyl)-3-(3-methylphenyl)-1,2,4-oxadiazole
ataluren
Conditions | Yield |
---|---|
With basic cobalt(II) carbonate; sodium bromide In acetic acid at 95℃; for 11h; Green chemistry; | 85% |
With pyridine; potassium permanganate In water at 85℃; for 6.5h; | 40% |
2-Fluorobenzoyl chloride
ataluren
Conditions | Yield |
---|---|
Stage #1: 3-Cyanobenzoic acid With hydroxylamine In water; tert-butyl alcohol at 38 - 41℃; for 21h; Stage #2: 2-Fluorobenzoyl chloride With triethylamine In water; tert-butyl alcohol at 27 - 40℃; for 7h; Stage #3: With hydrogenchloride; water Product distribution / selectivity; more than 3 stages; | 76% |
3-(N'-hydroxycarbamimidoyl)benzoic acid
o-fluoro-benzoic acid
ataluren
Conditions | Yield |
---|---|
With tetrachloromethane; diethoxymethylsilane; Bis(p-nitrophenyl) phosphate; triphenylphosphine In toluene at 120℃; for 24h; Reflux; Large scale; | 65% |
3-(N-hydroxycarbamimidoyl)-benzoic acid methyl ester
2-Fluorobenzoyl chloride
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: boron trifluoride diethyl etherate / 1,4-dioxane / 12.5 h / 0 °C / Reflux 2: sodium hydroxide; water / ethanol / 3 h / 20 °C View Scheme |
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydroxylamine hydrochloride; acetic acid / 3.5 h / 80 °C 2: pyridine; potassium permanganate / water / 6.5 h / 85 °C View Scheme |
o-fluoro-benzoic acid
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 3 h / 20 °C 2: hydroxylamine hydrochloride; acetic acid / 3.5 h / 80 °C 3: pyridine; potassium permanganate / water / 6.5 h / 85 °C View Scheme |
3-methylbenzenecarboximidamide hydrochloride
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 3 h / 20 °C 2: hydroxylamine hydrochloride; acetic acid / 3.5 h / 80 °C 3: pyridine; potassium permanganate / water / 6.5 h / 85 °C View Scheme |
3-Cyanobenzoic acid
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: potassium carbonate / N,N-dimethyl-formamide / 0.5 h / 20 °C 1.2: 4.33 h / 20 °C 2.1: hydroxylamine / ethanol; water / 1 h / 100 °C 3.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.33 h / 20 °C 4.1: toluene / 22 h / 5 - 130 °C / Dean-Stark 5.1: sodium hydroxide; water / tetrahydrofuran / 2 h / 100 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: potassium carbonate; hydroxylamine hydrochloride / water; ethanol / 3 h / Reflux 2.1: potassium carbonate / water; toluene / 0.08 h / 20 - 30 °C 2.2: 1 h / 0 - 10 °C 3.1: tert-butyl alcohol / 24 h / 80 °C View Scheme |
methyl 3-cyanobenzoate
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: hydroxylamine / ethanol; water / 1 h / 100 °C 2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.33 h / 20 °C 3: toluene / 22 h / 5 - 130 °C / Dean-Stark 4: sodium hydroxide; water / tetrahydrofuran / 2 h / 100 °C View Scheme | |
Multi-step reaction with 4 steps 1: hydroxylamine / ethanol; water / 20 °C / Reflux 2: trifluoroacetic acid / 0.58 h / 20 - 60 °C 3: palladium diacetate; triphenylphosphine; silver(I) acetate / toluene / 0.5 h / 150 °C / Microwave irradiation; Sealed tube 4: lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 20 °C View Scheme | |
Multi-step reaction with 4 steps 1: hydroxylamine / ethanol; water / 1 h / 100 °C 2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.33 h / 5 - 20 °C 3: toluene / 22 h / 5 - 130 °C / Dean-Stark apparatus 4: sodium hydroxide; water / tetrahydrofuran / 2 h / 100 °C View Scheme | |
Multi-step reaction with 4 steps 1: hydroxylamine hydrochloride; sodium ethanolate / ethanol / 20 h / 20 °C 2: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / 5 - 20 °C 3: tetrabutyl ammonium fluoride / tetrahydrofuran / 24 h / 20 °C 4: lithium hydroxide / tetrahydrofuran; water / 24 h / 20 °C View Scheme |
3-(carbamimidoyl)benzoic acid methyl ester
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.33 h / 20 °C 2: toluene / 22 h / 5 - 130 °C / Dean-Stark 3: sodium hydroxide; water / tetrahydrofuran / 2 h / 100 °C View Scheme |
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: palladium diacetate; triphenylphosphine; silver(I) acetate / toluene / 0.5 h / 150 °C / Microwave irradiation; Sealed tube 2: lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 20 °C View Scheme |
3-(N-hydroxycarbamimidoyl)-benzoic acid methyl ester
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: trifluoroacetic acid / 0.58 h / 20 - 60 °C 2: palladium diacetate; triphenylphosphine; silver(I) acetate / toluene / 0.5 h / 150 °C / Microwave irradiation; Sealed tube 3: lithium hydroxide monohydrate / water; tetrahydrofuran / 1 h / 20 °C View Scheme | |
Multi-step reaction with 3 steps 1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1.33 h / 5 - 20 °C 2: toluene / 22 h / 5 - 130 °C / Dean-Stark apparatus 3: sodium hydroxide; water / tetrahydrofuran / 2 h / 100 °C View Scheme |
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: hydroxylamine / water; methanol / 2.5 h / 50 °C 2.1: sodium hydrogencarbonate / water / 0.08 h / 20 - 30 °C 2.2: 1 h / 20 - 30 °C 3.1: toluene / 18 h / 85 °C 4.1: potassium dihydrogenphosphate; dihydrogen peroxide / water; acetonitrile / 20 - 30 °C 4.2: 5 h / 0 - 30 °C View Scheme |
3-Cyanobenzaldehyde
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: hydrogenchloride / water / 3.08 h / 20 - 45 °C 2.1: hydroxylamine / water; methanol / 2.5 h / 50 °C 3.1: sodium hydrogencarbonate / water / 0.08 h / 20 - 30 °C 3.2: 1 h / 20 - 30 °C 4.1: toluene / 18 h / 85 °C 5.1: potassium dihydrogenphosphate; dihydrogen peroxide / water; acetonitrile / 20 - 30 °C 5.2: 5 h / 0 - 30 °C View Scheme |
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: sodium hydrogencarbonate / water / 0.08 h / 20 - 30 °C 1.2: 1 h / 20 - 30 °C 2.1: toluene / 18 h / 85 °C 3.1: potassium dihydrogenphosphate; dihydrogen peroxide / water; acetonitrile / 20 - 30 °C 3.2: 5 h / 0 - 30 °C View Scheme |
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: toluene / 18 h / 85 °C 2.1: potassium dihydrogenphosphate; dihydrogen peroxide / water; acetonitrile / 20 - 30 °C 2.2: 5 h / 0 - 30 °C View Scheme |
3-(N-2-fluorobenzoylcarbamimidoyl)-benzoic acid methyl ester
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene / 22 h / 5 - 130 °C / Dean-Stark apparatus 2: sodium hydroxide; water / tetrahydrofuran / 2 h / 100 °C View Scheme |
3-(N-hydroxyamidino)benzoic acid methyl ester
ataluren
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / 5 - 20 °C 2: tetrabutyl ammonium fluoride / tetrahydrofuran / 24 h / 20 °C 3: lithium hydroxide / tetrahydrofuran; water / 24 h / 20 °C View Scheme |
ataluren
Conditions | Yield |
---|---|
With sodium hydroxide; water at 100℃; for 2h; Heating / reflux; | 96% |
With sodium hydroxide In ethanol; water |
ataluren
Conditions | Yield |
---|---|
Stage #1: ataluren With tetrakis(acetonitrile)copper(I)tetrafluoroborate; tetrabutylammonium tetra(tert-butyl alcohol) coordinate fluoride; copper(II) bis(trifluoromethanesulfonate) In acetonitrile at 23℃; for 0.5h; Sealed tube; Inert atmosphere; Stage #2: In acetonitrile at 35℃; for 24h; Irradiation; Sealed tube; Inert atmosphere; | 45% |
ataluren
2-(4,5-Dihydro-1,3-oxazol-2-yl)aniline
Conditions | Yield |
---|---|
Stage #1: ataluren With N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 0.5h; Inert atmosphere; Stage #2: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane at 20℃; for 2h; Inert atmosphere; Stage #3: 2-(4,5-Dihydro-1,3-oxazol-2-yl)aniline In dichloromethane at 20℃; for 72h; Inert atmosphere; | 25% |
Conditions | Yield |
---|---|
With Photinus pyralis luciferase aq. buffer; Enzymatic reaction; |
ataluren
Conditions | Yield |
---|---|
With magnesium methanolate In methanol; dichloromethane Reagent/catalyst; Solvent; |
ataluren
Conditions | Yield |
---|---|
With potassium hydroxide In tetrahydrofuran; water |
ataluren
2-amino-2-hydroxymethyl-1,3-propanediol
Conditions | Yield |
---|---|
In methanol; acetone Solvent; |
ataluren
L-lysine
Conditions | Yield |
---|---|
In tetrahydrofuran; water |
ataluren
L-arginine
Conditions | Yield |
---|---|
In ethanol; water Sonication; |
ataluren
L-histidine
Conditions | Yield |
---|---|
In ethanol; water Solvent; Sonication; |
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