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hangzhou verychem science and technology co.ltd

2,3-Dichlorobenzoylcyanide CAS:77668-42-9 Hangzhou Verychem Science And Technology Co. Ltd. was set up in year 2004, it’s a young but fast growing company. In the twelve years history, it invested two pharmaceutical raw material production

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $20.0

Type:Lab/Research institutions

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply (2,3-dichlorophenyl)oxoacetonitrile

Cas:77668-42-9

Min.Order:1

Negotiable

Type:Other

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2,3-Dichlorobenzoyl cyanide

Cas:77668-42-9

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

2,3-Dichlorobenzoyl cyanide

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $9.0 / 99.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company

TIANFU-CHEM - 2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 77668-42-9 with competitive price

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:10 Kilogram

FOB Price: $40.0 / 50.0

Type:Trading Company

inquiry

Hebei Sankai Chemical Technology Co., Ltd

1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd

2,3-DichlorobenzoylcyanideCAS77668-42-9

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $5.0 / 6.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

CAS No. 77668-42-9 Molecular formula C8H3NOCl2 Molecular weight 200.2 Appearance white solid Assay ≥98%

2,3-Dichlorobenzoyl cyanide CAS:77668-42-9

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2,3-Dichlorobenzoylcyanide 77668-42-9

Cas:77668-42-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the

2,3-Dichlorobenzoylcyanide/ LIDE PHARMA- Factory supply / Best price

Cas:77668-42-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

2,3-Dichlorobenzoyl cyanide CAS:77668-42-9 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organ

2,3-Dichlorobenzoyl cyanide CAS:77668-42-9

Cas:77668-42-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Product quality: Our company have high quality product , and also the product we have good manufacture . First of all, this product is of fine quality. Every finish should be checked by quality inspection system.And every one should be also tried

2,3-Dichlorobenzoylcyanide CAS NO.77668-42-9

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $80.0 / 90.0

Type:Trading Company

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,3-Dichloro Xophenylacetonitrile

Cas:77668-42-9

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:White or off-white Solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture.Organic synthesis Transportation:

2,3-Dichlorobenzoyl cyanide

Cas:77668-42-9

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

2,3-DICHLOROBENZOYLCYANIDE

Cas:77668-42-9

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

our strengths: 1: Fast and guaranteed shipment (TNT;EMS;FEDEX;DHL;UPS;EUB, special line) 2: Various payment items accepted (Btc; MoneyGram; WU) 3: Valued package (Paraffin coating; Double aluminum foil bag; Vacuum packaging) 4: Efficient delivery

Manufacturer/High quality 2,3-Dichlorobenzoyl cyanide

Cas:77668-42-9

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,3-Dichloro Xophenylacetonitrile

Cas:77668-42-9

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 2,3-Dichlorobenzoyl Cyanide CAS No.: 77668-42-9 Molecule Formula:C8H3Cl2NO Molecule Weight:200.02 Purity: 99.0% Package: 25kg/drum Description:White or off-white powder Manufacture Standards:Enterprise Standard TEST

Lower Price 2,3-Dichlorobenzoyl Cyanide in stock

Cas:77668-42-9

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

2,3-Dichlorobanzoyl nitrile

Cas:77668-42-9

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Shandong Mopai Biotechnology Co., LTD

Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W

2,3-Dichlorobenzoylcyanide

Cas:77668-42-9

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

copper(I) cyanide
544-92-3

copper(I) cyanide

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

Conditions
ConditionsYield
at 160 - 165℃; for 7h;94.2%
at 35 - 165℃; for 4h; Product distribution / selectivity;74%
With potassium iodide In chlorobenzene at 132 - 135℃; for 6h;
2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

copper(l) cyanide

copper(l) cyanide

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

Conditions
ConditionsYield
With potassium iodide In toluene for 1h; Inert atmosphere; Reflux;84%
With cetyltrimethylammonim bromide In toluene at 110℃; for 12h; Kinetics; Reagent/catalyst; Solvent; Large scale;77%
at 160℃; for 6h;
2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

sodium cyanide
143-33-9

sodium cyanide

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

Conditions
ConditionsYield
With copper(l) iodide In acetonitrile at 20℃; for 6 - 9h;80%
2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

copper(I) cyanide
544-92-3

copper(I) cyanide

A

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

B

2,3-dichlorobenzoic acid anhydride
252186-80-4

2,3-dichlorobenzoic acid anhydride

Conditions
ConditionsYield
at 35 - 165℃; for 6h; Product distribution / selectivity;A 57%
B 6.9%
2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

Conditions
ConditionsYield
With copper(l) cyanide at 160 - 165℃; for 6h;
2,3-dichlorbenzoic acid
50-45-3

2,3-dichlorbenzoic acid

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

Conditions
ConditionsYield
With thionyl chloride; mercury
Multi-step reaction with 2 steps
1: thionyl chloride / 2 h / Inert atmosphere; Reflux
2: cetyltrimethylammonim bromide / toluene / 12 h / 110 °C / Large scale
View Scheme
Multi-step reaction with 2 steps
1: thionyl chloride / 6 h
2: 6 h / 160 °C
View Scheme
2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

sodium cyanide
143-33-9

sodium cyanide

copper(I) cyanide
544-92-3

copper(I) cyanide

A

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

B

2,3-dichlorobenzoic acid anhydride
252186-80-4

2,3-dichlorobenzoic acid anhydride

Conditions
ConditionsYield
at 35 - 165℃; for 10h; Product distribution / selectivity;
2,3-dichlorbenzoic acid
50-45-3

2,3-dichlorbenzoic acid

copper(l) cyanide

copper(l) cyanide

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

Conditions
ConditionsYield
Stage #1: 2,3-dichlorbenzoic acid With thionyl chloride
Stage #2: copper(l) cyanide
sodium cyanide
773837-37-9

sodium cyanide

2,3-dichlorobenzoyl chloride
2905-60-4

2,3-dichlorobenzoyl chloride

A

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

B

2,3-dichlorobenzoic acid anhydride
252186-80-4

2,3-dichlorobenzoic acid anhydride

C

2,3-dichlorbenzoic acid
50-45-3

2,3-dichlorbenzoic acid

D

C16H6Cl4N2O2

C16H6Cl4N2O2

Conditions
ConditionsYield
With copper(l) chloride In para-xylene; acetonitrile Reagent/catalyst; Solvent;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidine bicarbonate
2582-30-1

aminoguanidine bicarbonate

2-(2,3-dichlorophenyl)-2-(aminoguanidine)-acetonitrile

2-(2,3-dichlorophenyl)-2-(aminoguanidine)-acetonitrile

Conditions
ConditionsYield
With methanesulfonic acid at 45℃; for 5h; Heating / reflux;82%
With methanesulfonic acid In toluene at 45℃; for 10h; Heating / reflux;79%
Stage #1: aminoguanidine bicarbonate With sulfuric acid In water at 25℃; for 0.5h;
Stage #2: 2,3-dichlorobenzoyl cyanide In water at 60℃; for 6h;
Stage #3: With sodium hydroxide; water at 25 - 60℃; for 1h; Product distribution / selectivity;
76.8%
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

3-phenylimino-2-indolinone
33828-98-7, 101671-27-6

3-phenylimino-2-indolinone

2‐oxo‐3‐(phenylamino)indoline‐3‐carbonitrile
32816-69-6

2‐oxo‐3‐(phenylamino)indoline‐3‐carbonitrile

Conditions
ConditionsYield
In methanol at 20℃; for 12h;80%
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidine bicarbonate
2582-30-1

aminoguanidine bicarbonate

2-(2,3-dichlorophenyl)-2-(guanidinylamino)acetonitrile

2-(2,3-dichlorophenyl)-2-(guanidinylamino)acetonitrile

Conditions
ConditionsYield
Stage #1: 2,3-dichlorobenzoyl cyanide; aminoguanidine bicarbonate With sulfuric acid In water at 55 - 60℃; for 6h;
Stage #2: With sodium hydroxide In water at 20℃; for 0.5h; pH=9 - 10;
78%
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

2-(2,3-dichlorophenyl)-2-(guanidinoimino)acetonitrile
84689-20-3

2-(2,3-dichlorophenyl)-2-(guanidinoimino)acetonitrile

Conditions
ConditionsYield
Stage #1: 2,3-dichlorobenzoyl cyanide With sulfuric acid; aminoguanidine bicarbonate In water; acetonitrile at 25 - 50℃; for 30h;
Stage #2: With ammonia; water pH=6 - 7;
Stage #3: With sodium hydroxide; water at 15 - 25℃; pH=9.5 - 10;
70.3%
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidine
79-17-4

aminoguanidine

2-(2,3-dichlorophenyl)-2-guanidinyliminoacetonitrile
84689-20-3

2-(2,3-dichlorophenyl)-2-guanidinyliminoacetonitrile

Conditions
ConditionsYield
With PPA In 1,2-dimethoxyethane67%
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

(Z)-N-guanyl-2-(2,3-dichlorophenyl)-2-imino-acetonitrile sulfate

(Z)-N-guanyl-2-(2,3-dichlorophenyl)-2-imino-acetonitrile sulfate

Conditions
ConditionsYield
Stage #1: aminoguanidine bicarbonate With sulfur trioxide In methanesulfonic acid at 20℃; for 0.333333h;
Stage #2: 2,3-dichlorobenzoyl cyanide In methanesulfonic acid at 45℃; for 4h;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidinium tetrafluoroborate

aminoguanidinium tetrafluoroborate

(Z)-N-guanyl-2-(2,3-dichlorophenyl)-2-imino-acetonitrile tetrafluoroborate

(Z)-N-guanyl-2-(2,3-dichlorophenyl)-2-imino-acetonitrile tetrafluoroborate

Conditions
ConditionsYield
In diethyl ether; acetonitrile at 45℃; for 4h; Product distribution / selectivity;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidinium tetrafluoroborate

aminoguanidinium tetrafluoroborate

lamotrigine
84057-84-1

lamotrigine

Conditions
ConditionsYield
Stage #1: 2,3-dichlorobenzoyl cyanide; aminoguanidinium tetrafluoroborate In diethyl ether; acetonitrile at 45℃; for 4h;
Stage #2: With sodium hydroxide In diethyl ether; water; acetonitrile at 50 - 70℃; for 1h; pH=> 12; Product distribution / selectivity;
tetrafluoroboric acid

tetrafluoroboric acid

2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

(Z)-N-guanyl-2-(2,3-dichlorophenyl)-2-imino-acetonitrile tetrafluoroborate

(Z)-N-guanyl-2-(2,3-dichlorophenyl)-2-imino-acetonitrile tetrafluoroborate

Conditions
ConditionsYield
Stage #1: tetrafluoroboric acid; aminoguanidine bicarbonate In water; acetonitrile at 15 - 30℃; for 0.166667 - 0.5h;
Stage #2: 2,3-dichlorobenzoyl cyanide In water; acetonitrile at 45℃; for 5 - 6h; Product distribution / selectivity;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidine bismesylate

aminoguanidine bismesylate

lamotrigine
84057-84-1

lamotrigine

Conditions
ConditionsYield
Stage #1: 2,3-dichlorobenzoyl cyanide; aminoguanidine bismesylate With methanesulfonic acid In acetonitrile at 65 - 70℃; for 1h;
Stage #2: With magnesium oxide In water; acetonitrile at 70℃; for 3.16667h;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

lamotrigine
84057-84-1

lamotrigine

Conditions
ConditionsYield
With potassium hydroxide
With potassium hydroxide
Stage #1: aminoguanidine bicarbonate With sulfur trioxide In methanesulfonic acid at 25℃; for 1h;
Stage #2: 2,3-dichlorobenzoyl cyanide In methanesulfonic acid at 45℃; for 5h;
Stage #3: With sodium hydroxide In methanesulfonic acid; water; acetonitrile at 20 - 70℃; for 3.5h; pH=> 12; Product distribution / selectivity;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

aminoguanidine bicarbonate
2582-30-1

aminoguanidine bicarbonate

2-(2,3-dichlorophenyl)-2-guanidinyliminoacetonitrile
84689-20-3

2-(2,3-dichlorophenyl)-2-guanidinyliminoacetonitrile

Conditions
ConditionsYield
Stage #1: aminoguanidine bicarbonate With sulfuric acid; toluene-4-sulfonic acid In toluene at 110℃; for 0.25h;
Stage #2: 2,3-dichlorobenzoyl cyanide In toluene at 80℃; for 3.5h; Heating / reflux;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

methanesulfonic acid
75-75-2

methanesulfonic acid

aminoguanidine hydrogencarbonate
2200-97-7, 2582-30-1, 10587-01-6, 13998-67-9

aminoguanidine hydrogencarbonate

2-(2,3-dichlorophenyl)-2-(aminoguanidine)-acetonitrile monomesylate

2-(2,3-dichlorophenyl)-2-(aminoguanidine)-acetonitrile monomesylate

Conditions
ConditionsYield
Stage #1: methanesulfonic acid With phosphorus pentoxide for 2h;
Stage #2: aminoguanidine hydrogencarbonate at 25 - 30℃; for 1h;
Stage #3: 2,3-dichlorobenzoyl cyanide at 20℃; for 24h;
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

methyl 2-(2,3-dichlorophenyl)-2-(2-p-tolylhydrazono)acetate

methyl 2-(2,3-dichlorophenyl)-2-(2-p-tolylhydrazono)acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2: thionyl chloride / 4.5 h / 40 - 64 °C
3: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

methyl 2-(2,3-dichlorophenyl)-2-(2-p-tolylhydrazono)acetate

methyl 2-(2,3-dichlorophenyl)-2-(2-p-tolylhydrazono)acetate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2: thionyl chloride / 4.5 h / 40 - 64 °C
3: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

7-chloro-1-methyl-1H-indazole-3-carboxylic acid

7-chloro-1-methyl-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2.1: thionyl chloride / 4.5 h / 40 - 64 °C
3.1: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
4.1: L-proline; caesium carbonate; copper(l) iodide / dimethyl sulfoxide / 7 h / 95 - 100 °C
4.2: pH 2 - 2.5
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

7-chloro-1-ethyl-1H-indazole-3-carboxylic acid

7-chloro-1-ethyl-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2.1: thionyl chloride / 4.5 h / 40 - 64 °C
3.1: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
4.1: L-proline; caesium carbonate; copper(l) iodide / dimethyl sulfoxide / 7 h / 75 - 80 °C
4.2: pH 2 - 2.5
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

7-chloro-1-phenyl-1H-indazole-3-carboxylic acid

7-chloro-1-phenyl-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2.1: thionyl chloride / 4.5 h / 40 - 64 °C
3.1: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
4.1: L-proline; caesium carbonate; copper(l) iodide / dimethyl sulfoxide / 6 h / 75 - 80 °C
4.2: pH 2 - 2.5
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

7-chloro-1-(4-methoxyphenyl)-1H-indazole-3-carboxylic acid

7-chloro-1-(4-methoxyphenyl)-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2.1: thionyl chloride / 4.5 h / 40 - 64 °C
3.1: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
4.1: L-proline; caesium carbonate; copper(l) iodide / dimethyl sulfoxide / 6 h / 70 - 75 °C
4.2: pH 2 - 2.5
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

7-chloro-1-p-tolyl-1H-indazole-3-carboxylic acid

7-chloro-1-p-tolyl-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2.1: thionyl chloride / 4.5 h / 40 - 64 °C
3.1: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
4.1: L-proline; caesium carbonate; copper(l) iodide / dimethyl sulfoxide / 6 h / 75 - 80 °C
4.2: pH 2 - 2.5
View Scheme
2,3-dichlorobenzoyl cyanide
77668-42-9

2,3-dichlorobenzoyl cyanide

7-chloro-1-(2,4-dichlorophenyl)-1H-indazole-3-carboxylic acid

7-chloro-1-(2,4-dichlorophenyl)-1H-indazole-3-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: water; sodium chloride; sulfuric acid / 1.5 h / 40 - 45 °C
2.1: thionyl chloride / 4.5 h / 40 - 64 °C
3.1: potassium carbonate / isopropyl alcohol / 6 h / 60 - 65 °C
4.1: L-proline; caesium carbonate; copper(l) iodide / dimethyl sulfoxide / 6 h / 95 - 100 °C
4.2: pH 2 - 2.5
View Scheme

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