The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:78715-23-8
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:78715-23-8
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:78715-23-8
Min.Order:1 Kilogram
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Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:78715-23-8
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:78715-23-8
Min.Order:10 Kilogram
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Type:Trading Company
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:78715-23-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct Name: NORBUPRENORPHINE Synonyms: NORBUPRENORPHINE;(aS,5a,7a)-a-(1,1-Dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-a-methyl-6,14-ethenomorphinan-7-methanol;N-De(cyclopropylmethyl)buprenorphine;N-Dealkylbuprenorphine;N-Des
Cas:78715-23-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:78715-23-8
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:78715-23-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiry1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:78715-23-8
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquiryWe are a Union of chemistry in China, consists of chemists,engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:78715-23-8
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiry1. Product advantages? High purity, all above 98.5%, no impurities after dissolution? We will test each batch to ensure quality? OEM and private brand services designed for free? Various cap colors available? We can also provide MT1 peptide powder2.
Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali
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Type:Lab/Research institutions
inquiryWe are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for
Cas:78715-23-8
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inquiryTIANFU-CHEM NORBUPRENORPHINE Application:TIANFU-CHEM NORBUPRENORPHINE
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
TIANFU-CHEM NORBUPRENORPHINEAppearance:white powder Storage:room temperature Package:200KG Application:Industrial Grade Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to airport) or by sea LCL/FCL fo
Cas:78715-23-8
Min.Order:0
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Type:Lab/Research institutions
inquiryStable supply of goods and provision of high-quality services Application:As raw materials in the field of medicine and biology
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
1.Professional synthesis laboratory and production base. 2.Strong synthesis team and service team. 3.Professional data management system. 4.We provide the professional test date and product information ,ex. HNMR ,CNMR,FNMR, HPLC/G
Cas:78715-23-8
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryChangzhou Extraordinary Pharmatech co., LTD. As a leading chemical manufacturer and supplier in China.DAS authentication is passed.We can provide the popular precursor chemicals, we have our own strong R & D team, have our own laboratories and fa
Best quality & Attractive price & Professional service; Trial & Pilot & CommercialHenan Fine Chemicals Co., LTD. is a diversified technology - oriented integrated company, which mainly concentrates on fine chemicals. Our company is committed to becom
Cas:78715-23-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryThe system can just identify the products information in first sheet, it is not be permitted to add or edit new sheet by userself.Our products are required in MG to Gram only. · Pharmaceutical Reference Standards· Traceable workin
6,14-Ethenomorphinan-7-methanol,a-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-a-methyl-, (aS,5a,7a)- Storage:keep in dry and cool condition Package:25kg or according to cutomer's demand Application:Chemical research/pharma interme
Cas:78715-23-8
Min.Order:0
Negotiable
Type:Trading Company
inquiryFINETECH INDUSTRY LIMITED is a LONDON based CRO company providing drug discovery & development services to worldwide clients. FINETECH INDUSTRY LIMITED supplies the Norbuprenorphine, CAS:78715-23-8 with the most competitive price and the best quality
We are a trading company aiming at providing high-quality services to customers. Established for many years, with good reputation in the industry Storage:Sealed and preserved Application:Fine chemical intermediates, used as the main raw material for
Cas:78715-23-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryTIANFU-CHEM NORBUPRENORPHINE Application:TIANFU-CHEM NORBUPRENORPHINE
norbuprenorphine
Conditions | Yield |
---|---|
With water; potassium hydroxide In diethylene glycol at 185℃; Product distribution / selectivity; Inert atmosphere; | 97.19% |
With potassium hydroxide In diethylene glycol at 100 - 200℃; for 1h; Inert atmosphere; | 3.2 g |
(S)-2-((4R,4aS,6R,7R,7aR,12bS)-7,9-dimethoxy-1,2,3,4,5,6,7,7a-octahydro-4a,7-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-6-yl)-3,3-dimethylbutan-2-ol
norbuprenorphine
Conditions | Yield |
---|---|
Stage #1: (S)-2-((4R,4aS,6R,7R,7aR,12bS)-7,9-dimethoxy-1,2,3,4,5,6,7,7a-octahydro-4a,7-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-6-yl)-3,3-dimethylbutan-2-ol With water; potassium hydroxide In diethylene glycol at 185℃; for 5.25h; Stage #2: With sulfuric acid In water; diethylene glycol at 90℃; pH=8.6; | 80% |
[5α,7α]-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-α,17-dimethyl-6,14-ethenomorphinan-7-methanol
A
(S)-2-((4R,4aS,6R,7R,7aR,12bS)-7,9-dimethoxy-1,2,3,4,5,6,7,7a-octahydro-4a,7-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-6-yl)-3,3-dimethylbutan-2-ol
B
norbuprenorphine
Conditions | Yield |
---|---|
With D-Galactose; Cunninghamella echinulata NRRL 1384 at 28 - 32℃; for 168h; Product distribution / selectivity; Microbiological reaction; Basal fermentation medium; | A 55% B 16.4% |
With Maltose; Cunninghamella echinulata NRRL 1384 at 28 - 32℃; for 168h; Product distribution / selectivity; Microbiological reaction; Basal fermentation medium; | A 47.2% B 13.2% |
With Sucrose; Cunninghamella echinulata NRRL 1384 at 28 - 32℃; for 168h; Product distribution / selectivity; Microbiological reaction; Basal fermentation medium; | A 42.4% B 12.1% |
1-[(5α,7α)-3-methoxy-4,5-epoxy-18,19-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-methoxy-6,14-ethenomorphinan-17-yl]ethanone
A
[5α,7α]-17-acetyl-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanolamide
B
(S)-2-((4R,4aS,6R,7R,7aR,12bS)-7,9-dimethoxy-1,2,3,4,5,6,7,7a-octahydro-4a,7-ethano-4,12-methanobenzofuro[3,2-e]isoquinolin-6-yl)-3,3-dimethylbutan-2-ol
C
norbuprenorphine
Conditions | Yield |
---|---|
With potassium hydroxide In diethylene glycol at 170 - 180℃; for 7h; Inert atmosphere; | A 42% B 10% C 35% |
1-[(5α,7α)-3-methoxy-4,5-epoxy-18,19-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-methoxy-6,14-ethenomorphinan-17-yl]ethanone
A
[5α,7α]-17-acetyl-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanolamide
B
norbuprenorphine
Conditions | Yield |
---|---|
With potassium hydroxide In diethylene glycol at 170 - 180℃; for 7h; Inert atmosphere; | A 37% B 40% |
norbuprenorphine
Conditions | Yield |
---|---|
With hydrogen; palladium 10% on activated carbon In methanol at 60℃; under 2068.65 Torr; for 2.5h; Product distribution / selectivity; |
1-[(5α,7α)-3-methoxy-4,5-epoxy-18,19-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-methoxy-6,14-ethenomorphinan-17-yl]ethanone
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: potassium hydroxide / diethylene glycol / 7 h / 170 - 180 °C / Inert atmosphere 2: potassium hydroxide / diethylene glycol / 7 h / 170 °C View Scheme | |
Multi-step reaction with 2 steps 1: potassium hydroxide / diethylene glycol / 7 h / 170 - 180 °C / Inert atmosphere 2: potassium hydroxide / diethylene glycol / 7 h / 170 °C View Scheme |
[5α,7α]-17-acetyl-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-6-methoxy-α-methyl-6,14-ethenomorphinan-7-methanolamide
norbuprenorphine
Conditions | Yield |
---|---|
With potassium hydroxide In diethylene glycol at 170℃; for 7h; | |
With Schwartz's reagent In tetrahydrofuran at 20℃; for 0.666667h; Reagent/catalyst; Inert atmosphere; |
[5α,7α]-α-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3,6-dimethoxy-α,17-dimethyl-6,14-ethenomorphinan-7-methanol
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: copper diacetate; palladium diacetate / 1,4-dioxane / 23 h / 80 °C 2: potassium hydroxide / diethylene glycol / 7 h / 170 - 180 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1: copper diacetate; palladium diacetate / 1,4-dioxane / 23 h / 80 °C 2: potassium hydroxide / diethylene glycol / 7 h / 170 - 180 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: copper diacetate; palladium diacetate / 1,4-dioxane / 23 h / 80 °C 2: potassium hydroxide / diethylene glycol / 7 h / 170 - 180 °C / Inert atmosphere 3: potassium hydroxide / diethylene glycol / 7 h / 170 °C View Scheme | |
Multi-step reaction with 3 steps 1: copper diacetate; palladium diacetate / 1,4-dioxane / 23 h / 80 °C 2: potassium hydroxide / diethylene glycol / 7 h / 170 - 180 °C / Inert atmosphere 3: potassium hydroxide / diethylene glycol / 7 h / 170 °C View Scheme | |
Multi-step reaction with 2 steps 1: chloroform / 12 h / Reflux 2: potassium hydroxide / diethylene glycol / 1 h / 100 - 200 °C / Inert atmosphere View Scheme |
N-nororipavine
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1: triethylamine / dichloromethane / 1.5 h / 20 °C / Inert atmosphere 2: toluene / 80 h / 20 - 80 °C / Inert atmosphere 3: tetrahydrofuran; toluene / 3 h / 50 - 60 °C / Inert atmosphere 4: lithium aluminium tetrahydride / tetrahydrofuran / 21 h / 20 - 70 °C / Inert atmosphere 5: hydrogen; palladium 10% on activated carbon; acetic acid / isopropyl alcohol; water; methanol / 144 h / 60 °C / 760.05 Torr View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: toluene / 80 h / 20 - 80 °C / Inert atmosphere 2: tetrahydrofuran; toluene / 3 h / 50 - 60 °C / Inert atmosphere 3: lithium aluminium tetrahydride / tetrahydrofuran / 21 h / 20 - 70 °C / Inert atmosphere 4: hydrogen; palladium 10% on activated carbon; acetic acid / isopropyl alcohol; water; methanol / 144 h / 60 °C / 760.05 Torr View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: tetrahydrofuran; toluene / 3 h / 50 - 60 °C / Inert atmosphere 2: lithium aluminium tetrahydride / tetrahydrofuran / 21 h / 20 - 70 °C / Inert atmosphere 3: hydrogen; palladium 10% on activated carbon; acetic acid / isopropyl alcohol; water; methanol / 144 h / 60 °C / 760.05 Torr View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: lithium aluminium tetrahydride / tetrahydrofuran / 21 h / 20 - 70 °C / Inert atmosphere 2: hydrogen; palladium 10% on activated carbon; acetic acid / isopropyl alcohol; water; methanol / 144 h / 60 °C / 760.05 Torr View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; hydrogen; acetic acid In methanol; water; isopropyl alcohol at 60℃; under 760.051 Torr; for 144h; |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene / 3 h / 60 °C / Inert atmosphere 2: Schwartz's reagent / tetrahydrofuran / 0.67 h / 20 °C / Inert atmosphere View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: palladium 10% on activated carbon; acetic acid / isopropyl alcohol; water / 72 h / 80 °C / 760.05 Torr 2: toluene / 3 h / 60 °C / Inert atmosphere 3: Schwartz's reagent / tetrahydrofuran / 0.67 h / 20 °C / Inert atmosphere View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: hydrogen; palladium 10% on activated carbon; acetic acid / isopropyl alcohol; water / 72 h / 80 °C / 760.05 Torr 2: Schwartz's reagent / tetrahydrofuran / 0.67 h / 20 °C / Inert atmosphere View Scheme |
7-acetyl-6,14-endo-ethano-6,7,8,14-tetrahydrothebaine
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: magnesium / diethyl ether; benzene 1.2: 6 h / Reflux 2.1: chloroform / 12 h / Reflux 3.1: potassium hydroxide / diethylene glycol / 1 h / 100 - 200 °C / Inert atmosphere View Scheme |
thevinone
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: palladium 10% on activated carbon; hydrogen / ethanol / 50 - 60 °C / 30003 - 37503.8 Torr 2.1: magnesium / diethyl ether; benzene 2.2: 6 h / Reflux 3.1: chloroform / 12 h / Reflux 4.1: potassium hydroxide / diethylene glycol / 1 h / 100 - 200 °C / Inert atmosphere View Scheme |
thebaine
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: 1 h / Reflux 2.1: palladium 10% on activated carbon; hydrogen / ethanol / 50 - 60 °C / 30003 - 37503.8 Torr 3.1: magnesium / diethyl ether; benzene 3.2: 6 h / Reflux 4.1: chloroform / 12 h / Reflux 5.1: potassium hydroxide / diethylene glycol / 1 h / 100 - 200 °C / Inert atmosphere View Scheme |
allyl bromide
norbuprenorphine
17-allyl-7α-[(2S)-3,3-dimethyl-2-hydroxybutan-2-yl]-4,5α-epoxy-3-hydroxy-6-methoxy-6α,14α-ethanomorphinan
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In N,N-dimethyl acetamide at 60℃; for 5h; | 97.2% |
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In 1-methyl-pyrrolidin-2-one at 80℃; for 18h; Inert atmosphere; | 86% |
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 80 - 100℃; for 4h; | |
With sodium hydrogencarbonate; potassium iodide In N,N-dimethyl-formamide at 85℃; for 5.5h; Product distribution / selectivity; | |
With sodium hydrogencarbonate In N,N-dimethyl-formamide at 62 - 85℃; Product distribution / selectivity; |
Conditions | Yield |
---|---|
With formic acid; [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; triethylamine In acetonitrile at 20 - 60℃; for 1h; Inert atmosphere; | 78% |
norbuprenorphine
methyl iodide
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In N,N-dimethyl acetamide at 20℃; for 24h; | 74% |
Conditions | Yield |
---|---|
Stage #1: Cyclopropanecarboxaldehyde; norbuprenorphine With hydrogen; platinum on activated charcoal In 1-methyl-pyrrolidin-2-one; methanol at 50℃; under 2068.65 Torr; for 2h; Stage #2: With hydrogenchloride In ethanol; water |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: [ruthenium(II)(η6-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]2; triethylamine; formic acid / acetonitrile / 1 h / 20 - 60 °C / Inert atmosphere 2: hydrogenchloride / ethanol; water / Heating View Scheme | |
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 13 h / 20 °C / Cooling with ice 2: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C 3: hydrogenchloride / ethanol; diethyl ether / 20 °C / pH 2 View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: triethylamine / dichloromethane / 13 h / 20 °C / Cooling with ice 2.1: lithium aluminium deuteride / tetrahydrofuran / 20 °C 2.2: pH 2 View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 13 h / 20 °C / Cooling with ice 2: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C 3: potassium carbonate / N,N-dimethyl-formamide / 15 h / 50 °C View Scheme |
norbuprenorphine
Buprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 13 h / 20 °C / Cooling with ice 2: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: triethylamine / dichloromethane / 13 h / 20 °C / Cooling with ice 2: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C 3: bromine / dichloromethane / 1 h / 30 °C / Cooling with ice 4: deuterium; triethylamine; palladium 10% on activated carbon / tetrahydrofuran / 24 h / 20 °C View Scheme |
norbuprenorphine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: triethylamine / dichloromethane / 13 h / 20 °C / Cooling with ice 2: lithium aluminium tetrahydride / tetrahydrofuran / 20 °C 3: bromine / dichloromethane / 1 h / 30 °C / Cooling with ice View Scheme |
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