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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Ethyl 7-Chloro-2-Oxohepanoate supplier in China

Cas:78834-75-0

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:white powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Ethyl 7-Chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethyl 7-Chloro-2-Oxohepanoate

Cas:78834-75-0

Min.Order:1

Negotiable

Type:Other

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Ethyl 7-Chloro-2-Oxoheptanoate

Cas:78834-75-0

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Ethyl 7-chloro-2-oxoheptanoate CAS 78834-75-0 7-Chloro-2-oxoheptanoic acid ethyl ester CAS no 78834-75-0 Heptanoic acid,7-chloro-2-oxo-, ethyl ester Ethyl 7-chloro-2-oxoheptanoate 7-Chloro-2-oxoheptanoic acid ethyl ester Heptanoic acid,7-chlo

Henan Tianfu Chemical Co., Ltd.

Tianfu Chemical, built in 2009, is a professional supplier for API materials in China. With 10 years development, we have bulit our own factory and lab to produce a certain of products. And we have established stable business relationship

TIANFU CHEM 78834-75-0 Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

FOB Price: $200.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

FOB Price: $3.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Top Purity CAS 78834-75-0 with fast shipping

Cas:78834-75-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Ethyl 7-chloro-2 -oxoheptanoate Chemical name:Ethyl 7-chloro-2 -oxoheptanoate Molecular formula:C9H15ClO3 Molecular weight:206.7 CAS:78834-75-0 Application:Intermediate for Cilastat

Ethyl 7-chloro-2 -oxoheptanoate CAS:78834-75-0

Cas:78834-75-0

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Heptanoic acid,7-chloro-2-oxo-, ethyl ester 78834-75-0

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

Ethyl 7-chloro-2-oxoheptanoate CAS:78834-75-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality or

Ethyl 7-chloro-2-oxoheptanoate CAS:78834-75-0

Cas:78834-75-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Heptanoic acid,7-chloro-2-oxo-, ethyl ester

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Heptanoic acid,7-chloro-2-oxo-, ethyl ester

Cas:78834-75-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Triumph International Development Limilted

Appearance:white or light yellow crystalline powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and als

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

ETHYL 7-CHLORO-2-OXOHEPTANOATEAppearance:Pls see the Details Storage:Keep away of light, hot, water, Store in dry, dark and ventilated place Package:according to customers' requirements Application:Steroids, Cosmetics Ingredients, APIs, Intermediates

ETHYL 7-CHLORO-2-OXOHEPTANOATE

Cas:78834-75-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Pale yellow clear liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:as per your request Application:Used as Pharmaceutical Intermediates,

Ethyl 7-chloro-2-oxoheptanoate.

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Siwei Development Group Ltd.

Product name: Ethyl 7-Chloro-2-Oxoheptanoate CAS No.:78834-75-0 Molecule Formula:C9H15ClO3 Molecule Weight:206.67 Purity: 99.0% Package: 140kg/drum Description:Light yellow liquid Manufacture Standards:Enterprise Standard

Best Quality Ethyl 7-Chloro-2-Oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Huarong Industrial Group Limited established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World.

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

Ethyl7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

Hefei TNJ chemical industry co.,ltd

TNJ is a chemical company since 2001. Our specialization, your Confidence ! We keep committing to meet the needs of both market and customers with our innovative technology, high stable quality products and excellent service. We always combine econ

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

Ethyl 7-chloro-2-oxoheptanoate Basic information Product Name: Ethyl 7-chloro-2-oxoheptanoate Synonyms: 7-Chloro-2-oxoheptanoic acid ethyl ester;Ethyl 7-chloro-2-oxohepanoate;ETHYL 7-CHLORO-2-OXOHEPTANOATE;Ethyl 7-Chloro-2-Otoheptanoate;ALPHA

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

Ethyl 7-chloro-2-oxoheptanoate

Cas:78834-75-0

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

1-bromo-5-chloropentane
54512-75-3

1-bromo-5-chloropentane

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Stage #1: 1-bromo-5-chloropentane; oxalic acid diethyl ester In tetrahydrofuran at -25 - -10℃; for 1h; Inert atmosphere;
Stage #2: With hydrogenchloride In tetrahydrofuran; water at 0℃; Reagent/catalyst; Inert atmosphere;
99.1%
Stage #1: 1-bromo-5-chloropentane With magnesium
Stage #2: oxalic acid diethyl ester In tetrahydrofuran at -15℃;
Stage #3: With hydrogenchloride In tetrahydrofuran Product distribution / selectivity;
90%
Grignard Reaction;
ethyl 7-chloro-α-hydroxyheptylate
1174680-07-9

ethyl 7-chloro-α-hydroxyheptylate

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at -2 - 8℃; for 3h;97%
With sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide In dichloromethane; water at -1 - 5℃; for 2.5h; Product distribution / selectivity;
C9H16ClO6S(1-)*Na(1+)

C9H16ClO6S(1-)*Na(1+)

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
With hydrogenchloride In water; toluene at 50 - 55℃; for 2h; Temperature; Solvent;86.5%
ethanol
64-17-5

ethanol

C7H10ClNO

C7H10ClNO

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
With sulfuric acid at 90℃; for 3.5h; Temperature;78%
5-chloro-n-pentylmagnesium bromide
278605-08-6

5-chloro-n-pentylmagnesium bromide

oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Stage #1: 5-chloro-n-pentylmagnesium bromide; oxalic acid diethyl ester In tetrahydrofuran at -30 - 5℃;
Stage #2: With hydrogenchloride In tetrahydrofuran Product distribution / selectivity;
74%
ethyl (E)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate
1022895-93-7

ethyl (E)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate

A

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

B

(S)-2,2-dimethylcyclopropanecarboxamide
75885-58-4

(S)-2,2-dimethylcyclopropanecarboxamide

Conditions
ConditionsYield
Stage #1: ethyl (E)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate With toluene-4-sulfonic acid In dichloromethane at 20℃;
Stage #2: With sodium hydroxide; water In dichloromethane pH=8 - 9; Product distribution / selectivity;
Stage #1: ethyl (E)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate With methanesulfonic acid In toluene at 30℃;
Stage #2: With sodium hydroxide; water In toluene pH=8 - 9; Product distribution / selectivity;
6-chloro-1-hexanol
2009-83-8

6-chloro-1-hexanol

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: sodium hydrogencarbonate; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / potassium bromide / dichloromethane; water / 0.83 h / -5 - 10 °C
2.1: sodium hydrogensulfite / water / 2.67 h / 5 °C
2.2: 12 h / 5 - 20 °C
3.1: hydrogenchloride; water / 140 h / 25 °C
4.1: sulfuric acid / Reflux
5.1: sodium hydrogencarbonate; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / potassium bromide / dichloromethane; water / 2.5 h / -1 - 5 °C
View Scheme
6-chlorohexanal
52387-36-7

6-chlorohexanal

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: sodium hydrogensulfite / water / 2.67 h / 5 °C
1.2: 12 h / 5 - 20 °C
2.1: hydrogenchloride; water / 140 h / 25 °C
3.1: sulfuric acid / Reflux
4.1: sodium hydrogencarbonate; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / potassium bromide / dichloromethane; water / 2.5 h / -1 - 5 °C
View Scheme
Multi-step reaction with 4 steps
1.1: water; sodium hydrogensulfite / 1 h / 35 °C
1.2: 0.5 h / 35 - 40 °C
2.1: water; potassium carbonate; dihydrogen peroxide / dimethyl sulfoxide / 5 h / 35 - 40 °C
3.1: sulfuric acid / 9 h / Reflux
4.1: sodium hydrogencarbonate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hypochlorite / water; dichloromethane / 3 h / -2 - 8 °C
View Scheme
7-chloro-2-hydroxyheptanoic acid
1174680-06-8

7-chloro-2-hydroxyheptanoic acid

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sulfuric acid / Reflux
2: sodium hydrogencarbonate; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / potassium bromide / dichloromethane; water / 2.5 h / -1 - 5 °C
View Scheme
7-chloro-α-hydroxyheptonitrile
1174680-05-7

7-chloro-α-hydroxyheptonitrile

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: hydrogenchloride; water / 140 h / 25 °C
2: sulfuric acid / Reflux
3: sodium hydrogencarbonate; sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical / potassium bromide / dichloromethane; water / 2.5 h / -1 - 5 °C
View Scheme
Multi-step reaction with 3 steps
1: water; potassium carbonate; dihydrogen peroxide / dimethyl sulfoxide / 5 h / 35 - 40 °C
2: sulfuric acid / 9 h / Reflux
3: sodium hydrogencarbonate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; potassium bromide; sodium hypochlorite / water; dichloromethane / 3 h / -2 - 8 °C
View Scheme
7-chloro(1-oxoethyl)heptanoic acid ethyl ester

7-chloro(1-oxoethyl)heptanoic acid ethyl ester

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Conditions
ConditionsYield
Stage #1: 7-chloro(1-oxoethyl)heptanoic acid ethyl ester With nitrosylsulfuric acid at 0 - 5℃; for 1h;
Stage #2: With formaldehyd In 1,2-dichloro-ethane at 0 - 25℃; for 2h;
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

(S)-2,2-dimethylcyclopropanecarboxamide
75885-58-4

(S)-2,2-dimethylcyclopropanecarboxamide

(Z)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid ethyl ester
877758-94-6

(Z)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid ethyl ester

Conditions
ConditionsYield
Stage #1: ethyl-7-Chloro-2-oxoheptanoate; (S)-2,2-dimethylcyclopropanecarboxamide With toluene-4-sulfonic acid In toluene for 10h; Reflux;
Stage #2: at 30℃; for 1h; Solvent; Temperature; Irradiation;
99.5%
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

triphenylborane
960-71-4

triphenylborane

C15H21ClO2

C15H21ClO2

Conditions
ConditionsYield
With phosphorous acid trimethyl ester In tetrahydrofuran at 50℃;60%
aqueous formalin

aqueous formalin

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

1-bromo-5-chloropentane
54512-75-3

1-bromo-5-chloropentane

sodium carbonate
497-19-8

sodium carbonate

7-chloro(1-oxoethyl)heptanoic acid ethyl ester

7-chloro(1-oxoethyl)heptanoic acid ethyl ester

Conditions
ConditionsYield
With nitrosylsulfuric acid; sulfuric acid In water; toluene
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

(S)-2,2-dimethylcyclopropanecarboxamide
75885-58-4

(S)-2,2-dimethylcyclopropanecarboxamide

A

(Z)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid ethyl ester
877758-94-6

(Z)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid ethyl ester

B

ethyl (E)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate
1022895-93-7

ethyl (E)-7-chloro-2-((S)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoate

ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

(S)-2,2-dimethylcyclopropanecarboxamide
75885-58-4

(S)-2,2-dimethylcyclopropanecarboxamide

ethyl 7-chloro-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoate
1022895-92-6

ethyl 7-chloro-2-{[(1S)-2,2-dimethylcyclopropyl]formamido}hept-2-enoate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 20h; Heating / reflux;
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

(S)-2,2-dimethylcyclopropanecarboxamide
75885-58-4

(S)-2,2-dimethylcyclopropanecarboxamide

A

(Z)-7-chloro-2 ((2s)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid
877674-77-6

(Z)-7-chloro-2 ((2s)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid

B

(E)-7-chloro-2[[(1S)-2,2-dimethyl cyclopropane]carboxamide]-2-heptenoic acid

(E)-7-chloro-2[[(1S)-2,2-dimethyl cyclopropane]carboxamide]-2-heptenoic acid

Conditions
ConditionsYield
Stage #1: ethyl-7-Chloro-2-oxoheptanoate; (S)-2,2-dimethylcyclopropanecarboxamide; toluene-4-sulfonic acid In toluene for 20h; Reflux;
Stage #2: With water; sodium hydroxide In toluene at 5 - 30℃; for 8h;
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

cilastatine
82009-34-5

cilastatine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid / toluene / 20 h / Reflux
1.2: 8 h / 5 - 30 °C
2.1: sodium hydroxide / methanol / 60 - 65 °C
2.2: pH 7
View Scheme
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / toluene / 20 h / Reflux
1.2: 8 h / 5 - 30 °C
2.1: hydrogenchloride / toluene; water / 4 h / 25 - 30 °C
3.1: sodium hydroxide / methanol / 60 - 65 °C
3.2: pH 7
View Scheme
Multi-step reaction with 3 steps
1: toluene-4-sulfonic acid / toluene / 10 h / 130 °C
2: sodium hydroxide / cyclohexane; 1,4-dioxane / 12 h / 20 °C
3: 8.5 h / 55 - 60 °C / Inert atmosphere
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

(Z)-7-chloro-2 ((2s)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid
877674-77-6

(Z)-7-chloro-2 ((2s)-2,2-dimethylcyclopropanecarboxamido)-2-heptenoic acid

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: toluene-4-sulfonic acid / toluene / 20 h / Reflux
1.2: 8 h / 5 - 30 °C
2.1: hydrogenchloride / toluene; water / 4 h / 25 - 30 °C
View Scheme
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / toluene / 10 h / 130 °C
2: sodium hydroxide / cyclohexane; 1,4-dioxane / 12 h / 20 °C
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

cilastatin sodium

cilastatin sodium

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / toluene / 20 h / Reflux
1.2: 8 h / 5 - 30 °C
2.1: sodium hydroxide / methanol / 60 - 65 °C
2.2: pH 7
3.1: triethylamine / butan-1-ol / 25 - 30 °C
3.2: 3 h / 25 - 30 °C
View Scheme
Multi-step reaction with 4 steps
1.1: toluene-4-sulfonic acid / toluene / 20 h / Reflux
1.2: 8 h / 5 - 30 °C
2.1: hydrogenchloride / toluene; water / 4 h / 25 - 30 °C
3.1: sodium hydroxide / methanol / 60 - 65 °C
3.2: pH 7
4.1: triethylamine / butan-1-ol / 25 - 30 °C
4.2: 3 h / 25 - 30 °C
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

α-Brom-δ-chlorvaleriansaeure-ethylester

α-Brom-δ-chlorvaleriansaeure-ethylester

Conditions
ConditionsYield
With bromine In tetrachloromethane at 20℃; for 1h;
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-chloropropyl)thiazole-4-carboxylate
1235034-74-8

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-chloropropyl)thiazole-4-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bromine / tetrachloromethane / 1 h / 20 °C
2: ethanol / 6 h / 50 °C / Inert atmosphere
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-iodopropyl)thiazole-4-carboxylate
1235034-75-9

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-iodopropyl)thiazole-4-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: bromine / tetrachloromethane / 1 h / 20 °C
2: ethanol / 6 h / 50 °C / Inert atmosphere
3: sodium iodide / acetonitrile / 5 h / 90 °C / Inert atmosphere
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

C32H30N4O4S2

C32H30N4O4S2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: bromine / tetrachloromethane / 1 h / 20 °C
2.1: ethanol / 6 h / 50 °C / Inert atmosphere
3.1: sodium iodide / acetonitrile / 5 h / 90 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 20 °C
4.2: 1 h
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-phenoxypropyl)thiazole-4-carboxylic acid
1235032-77-5

2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(3-phenoxypropyl)thiazole-4-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: bromine / tetrachloromethane / 1 h / 20 °C
2.1: ethanol / 6 h / 50 °C / Inert atmosphere
3.1: sodium iodide / acetonitrile / 5 h / 90 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide / 0.08 h / 20 °C
4.2: 1 h
5.1: hydrogenchloride / water
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

3-bromo-7-chloro-2-oxoheptanoate
1235035-22-9

3-bromo-7-chloro-2-oxoheptanoate

Conditions
ConditionsYield
With bromine In tetrachloromethane at 20℃; for 1h;
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(4-chlorobutyl)thiazole-4-carboxylate
1235035-23-0

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(4-chlorobutyl)thiazole-4-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: bromine / tetrachloromethane / 1 h / 20 °C
2: N,N-dimethyl-formamide; ethanol / 6 h / 20 °C / Inert atmosphere
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(4-iodobutyl)thiazole-4-carboxylate
1235035-24-1

ethyl 2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)-5-(4-iodobutyl)thiazole-4-carboxylate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: bromine / tetrachloromethane / 1 h / 20 °C
2: N,N-dimethyl-formamide; ethanol / 6 h / 20 °C / Inert atmosphere
3: sodium iodide / acetonitrile / 5 h / 90 °C / Inert atmosphere
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

C38H34N8O4S2

C38H34N8O4S2

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: bromine / tetrachloromethane / 1 h / 20 °C
2.1: N,N-dimethyl-formamide; ethanol / 6 h / 20 °C / Inert atmosphere
3.1: sodium iodide / acetonitrile / 5 h / 90 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C
4.2: 2 h / 20 °C
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

5-(4-(4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy)butyl)-2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylic acid
1235033-32-5

5-(4-(4-(1H-pyrazolo[3,4-d]pyrimidin-1-yl)phenoxy)butyl)-2-(8-(benzo[d]thiazol-2-ylcarbamoyl)-3,4-dihydroisoquinolin-2(1H)-yl)thiazole-4-carboxylic acid

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: bromine / tetrachloromethane / 1 h / 20 °C
2.1: N,N-dimethyl-formamide; ethanol / 6 h / 20 °C / Inert atmosphere
3.1: sodium iodide / acetonitrile / 5 h / 90 °C / Inert atmosphere
4.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.5 h / 20 °C
4.2: 2 h / 20 °C
5.1: sodium hydroxide / methanol; tetrahydrofuran; water / 5 h / 70 °C
View Scheme
ethyl-7-Chloro-2-oxoheptanoate
78834-75-0

ethyl-7-Chloro-2-oxoheptanoate

Reaxys ID: 30580581

Reaxys ID: 30580581

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