Hebei Sankai Chemical Technology Co., Ltd
1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd
Cas:863971-44-2
Min.Order:1 Kilogram
FOB Price: $5.0 / 10.0
Type:Trading Company
inquiryShanghai Upbio Tech Co.,Ltd
1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:863971-44-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryLIDE PHARMACEUTICALS LIMITED
Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the
Cas:863971-44-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryQingdao Beluga Import and Export Co., LTD
(5S,9S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,9-diisopropyl-12-Methoxy-4,10-diMethyl-3,6,8-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid CAS:863971-44-2 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological comp
Cas:863971-44-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryShandong Hanjiang Chemical Co., Ltd.
Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:863971-44-2
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co., Ltd.
Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryWuhan Han Sheng New Material Technology Co.，Ltd
Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:863971-44-2
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryZibo Hangyu Biotechnology Development Co., Ltd
Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:863971-44-2
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryXiamen Jenny Chemical Technology Co., Ltd.
GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,
Cas:863971-44-2
Min.Order:1 Milligram
Negotiable
Type:Trading Company
inquiryEAST CHEMSOURCES LIMITED
factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:863971-44-2
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiryShandong Mopai Biotechnology Co., LTD
Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:863971-44-2
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryKAISA GROUP INC
1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer
Cas:863971-44-2
Min.Order:1 Metric Ton
FOB Price: $1.5
Type:Trading Company
inquirySAGECHEM LIMITED
SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in custom synthe
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryWin-Win chemical Co.Ltd
Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryBluecrystal chem-union
We are a Union of chemistry in China, consists of chemists，engineers, laboratories,factories in China. We organize surplus capacity of R&D and production as well as custom synthesis for chemical products and chemical business project. We are supp
Cas:863971-44-2
Min.Order:1 Metric Ton
FOB Price: $1.0
Type:Trading Company
inquiryHangzhou Dingyan Chem Co., Ltd
R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Manufacturers
inquiryHangzhou J&H Chemical Co., Ltd.
J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHenan Tianfu Chemical Co., Ltd.
1.Our services：A.Supply sampleB.The packing also can be according the customers` requirmentC.Any inquiries will be replied within 24 hoursD.we provide Commerical Invoice, Packing List, Bill of loading, COA , Health certificate and Origin certificate.
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryXian Changyue Biological Technology Co., Ltd.
best seller Application:API
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Manufacturers
inquiryAntimex Chemical Limied
Our own factory produces direct sales with absolute price advantage Application:Pharmaceutical industry Transportation:By sea Port:Shanghai/tianjin
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHubei Langyou International Trading Co., Ltd
Fmoc-3vvd-OH CAS NO.863971-44-2 Application:Fmoc-3vvd-OH CAS NO.863971-44-2
DB BIOTECH CO., LTD
best seller Application:API
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Trading Company
inquiryWuhan ZeShanCheng Biomedical Technology Co., Ltd.
1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highl
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Trading Company
inquiryHenan Kanbei Chemical Co.,LTD
factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryHebei Quanhe Biotechnology Co. LTD
1. Timely and efficient service to ensure communication with customers2. Produce products of different specifications and sizes according to your requirements.3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures sta
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryShanghai Chinqesen Biotechnology Co., Ltd.
Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen
Hunan Longxianng Runhui Trading Co.,Ltd
Fmoc-3vvd-OH CAS NO.863971-44-2Appearance:powder crystal Storage:Keep in dry and cool place Package:Jinbo with Application:used in medical research Transportation:By express (Door to door) such as FEDEX, DHL, EMS for small amount. By air(airport to a
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryShanghai Yuanye Bio-Technology Co., Ltd.
good quality, competitive price, thoughtful after sale serviceAppearance:white powder Storage:Keep it in dry,shady and cool place Package:500mg Application:Pharma;Industry;Agricultural;chemical reaserch Transportation:by express or by sea Port:Any po
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Trading Company
inquirySaiwante (shanghai) New Material Technology Co., Ltd.
Stable supply of goods and provision of high-quality services Application:As raw materials in the field of medicine and biology
Hebei Muhuang Technology Co., Ltd
best seller Application:API
Cas:863971-44-2
Min.Order:0
Negotiable
Type:Trading Company
inquirySynthetic route
-
-
474645-25-5
tert-butyl (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oate
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With trifluoroacetic acid In dichloromethane at 20℃; for 2h; | 86% |
| With trifluoroacetic acid In dichloromethane | |
| With trifluoroacetic acid In dichloromethane |
-
-
177423-00-6
(3R,4S,5S)-4-[(2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme | |
| Multi-step reaction with 2 steps 1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 2: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme | |
| Multi-step reaction with 2 steps 1: N-ethyl-N,N-diisopropylamine; diethyl dicarbonate / ethyl acetate / 20 °C 2: trifluoroacetic acid / dichloromethane / 20 °C View Scheme |
-
-
474645-22-2
tert-Butyl (3R,4S,5S)-3-methoxy-4-(N-methylamino)-5-methylheptanoate
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 2-bromo-1-ethylpyridin-1-ium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / -10 - 20 °C 2: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C 3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme | |
| Multi-step reaction with 4 steps 1: N-ethyl-N,N-diisopropylamine; 2-bromo-1-ethylpyridinium tetrafluoroborate / dichloromethane / 20 h / -10 - 20 °C 2: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C 3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme |
-
-
1149-26-4
(S)-N-(benzyloxycarbonyl)valine
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 2-bromo-1-ethylpyridin-1-ium tetrafluoroborate; N-ethyl-N,N-diisopropylamine / dichloromethane / 20 h / -10 - 20 °C 2: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C 3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme | |
| Multi-step reaction with 4 steps 1: N-ethyl-N,N-diisopropylamine; 2-bromo-1-ethylpyridinium tetrafluoroborate / dichloromethane / 20 h / -10 - 20 °C 2: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C 3: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 4: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme |
-
-
120205-52-9
tert-butyl (3R,4S,5S)-4-[(2S)-2-[[(benzyloxy)carbonyl]amino]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C 2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme | |
| Multi-step reaction with 3 steps 1: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C 2: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 20 °C 3: trifluoroacetic acid / dichloromethane / 2 h / 20 °C View Scheme |
-
-
68858-20-8
Fmoc-Val-OH
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 2-chloro-4,6-dimethoxy-1 ,3,5-triazine / 20 °C 2: diethylamine / tetrahydrofuran / 20 °C 3: N-ethyl-N,N-diisopropylamine; diethyl dicarbonate / ethyl acetate / 20 °C 4: trifluoroacetic acid / dichloromethane / 20 °C View Scheme |
-
-
1375415-93-2
tert-butyl (3R,4S,5S)-4-[(2S)-2-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-N,3-dimethylbutanamido]-3-methoxy-5-methylheptanoate
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: diethylamine / tetrahydrofuran / 20 °C 2: N-ethyl-N,N-diisopropylamine; diethyl dicarbonate / ethyl acetate / 20 °C 3: trifluoroacetic acid / dichloromethane / 20 °C View Scheme |
-
-
120205-48-3
tert-Butyl (3R,4S,5S)-3-methoxy-4-(N-methylamino)-5-methylheptanoate hydrochloride
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1: 2-chloro-4,6-dimethoxy-1 ,3,5-triazine / 20 °C 2: diethylamine / tetrahydrofuran / 20 °C 3: N-ethyl-N,N-diisopropylamine; diethyl dicarbonate / ethyl acetate / 20 °C 4: trifluoroacetic acid / dichloromethane / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
1352201-70-7
(2R,3R)-3-methoxy-2-methyl-N-[(2S)-1-(1,2-oxazinan-2-yl)-1-oxo-3-phenylpropan-2-yl]-3-[(2S)-pyrrolidin-2-yl]propanamide, trifluoroacetic acid salt
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 3h; | 100% |
| With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 3h; | 100% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
1352201-95-6
(2R,3R)-3-methoxy-2-methyl-N-[(2S,3S)-1-(1,2-oxazinan-2-yl)-1-oxo-3-phenylbutan-2-yl]-3-[(2S)-pyrrolidin-2-yl]propanamide, trifluoroacetic acid salt
| Conditions | Yield |
|---|---|
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; | 100% |
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; | 100% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide at 20℃; for 1h; | 98% |
| With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 1h; | 98% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
24424-99-5
di-tert-butyl dicarbonate
| Conditions | Yield |
|---|---|
| Stage #1: (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid With piperidine In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: di-tert-butyl dicarbonate In 1,4-dioxane; water pH=11; | 97% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With diethyl cyanophosphonate; N-ethyl-N,N-diisopropylamine In dichloromethane for 1h; | 87% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With diethyl cyanophosphonate; N-ethyl-N,N-diisopropylamine In dichloromethane at 20℃; for 2h; | 81% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane; N,N-dimethyl-formamide at 20 - 30℃; for 1h; Inert atmosphere; | 81% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane; N,N-dimethyl-formamide at 20℃; for 1h; Temperature; Solvent; Inert atmosphere; | 75.8% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
1438851-45-6
(2R,3R)-3-methoxy-2-methyl-N-[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]-3-[(2S)-pyrrolidin-2-yl]propanethioamide, trifluoroacetic acid salt
| Conditions | Yield |
|---|---|
| With triethylamine; HATU In dichloromethane; N,N-dimethyl-formamide | 75% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
1369426-89-0
benzyl N-{(2R,3R)-3-methoxy-2-methyl-3-[(2S)-pyrrolidin-2-yl]propanoyl}-L-phenylalaninate trifluoroacetate
| Conditions | Yield |
|---|---|
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; | 68% |
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; | 68% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; HATU In dichloromethane; N,N-dimethyl-formamide for 2h; | 66% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In dichloromethane; N,N-dimethyl-formamide at 20 - 30℃; for 1h; Inert atmosphere; | 54.9% |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 3.5h; | 35% |
| Stage #1: (5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H-fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 1.5h; Stage #2: (2R,3R)-3-methoxy-2-methyl-3-[(2S)-pyrrolidin-2-yl]propanoic acid trifluoroacetate With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 2h; | 35% |
-
-
6066-82-6
1-hydroxy-pyrrolidine-2,5-dione
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
920017-35-2
Fmoc-MeVal-Val-Dil-OSu
| Conditions | Yield |
|---|---|
| With dicyclohexyl-carbodiimide In tetrahydrofuran at 20℃; for 48h; |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| With N-ethyl-N,N-diisopropylamine; HATU In N,N-dimethyl-formamide for 6h; not specified; |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
1438851-45-6
(2R,3R)-3-methoxy-2-methyl-N-[(1S)-2-phenyl-1-(1,3-thiazol-2-yl)ethyl]-3-[(2S)-pyrrolidin-2-yl]propanethioamide, trifluoroacetic acid salt
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1: HATU; triethylamine / dichloromethane; N,N-dimethyl-formamide 2: diethylamine / dichloromethane View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme | |
| Multi-step reaction with 5 steps 1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2: sodium hydroxide / 1,4-dioxane; water / pH 11 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C 5.1: dichloromethane / 0.5 h / 20 °C View Scheme | |
| Multi-step reaction with 6 steps 1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2: sodium hydroxide / 1,4-dioxane; water / pH 11 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h / 20 °C 6: dichloromethane / 0.5 h / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
474645-27-7
[3H]-Vedotin
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.08 h / 20 °C 5.1: trifluoroacetic acid / dichloromethane View Scheme | |
| Multi-step reaction with 6 steps 1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2: sodium hydroxide / 1,4-dioxane; water / pH 11 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 6: dichloromethane View Scheme | |
| Multi-step reaction with 2 steps 1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide; dichloromethane / 20 °C 2: diethylamine / dichloromethane / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.08 h / 20 °C View Scheme | |
| Multi-step reaction with 5 steps 1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2: sodium hydroxide / 1,4-dioxane; water / pH 11 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
-
-
1369427-27-9
(S)-2-((2R,3R)-3-((S)-1-((6S,9S,12S,13R)-12-((S)-sec-butyl)-6,9-diisopropyl-13-methoxy-2,2,5,11-tetramethyl-4,7,10-trioxo-3-oxa-5,8,11-triazapentadecan-15-oyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / methanol View Scheme | |
| Multi-step reaction with 4 steps 1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2: sodium hydroxide / 1,4-dioxane; water / pH 11 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.17 h / 20 °C 4: palladium 10% on activated carbon; hydrogen / methanol / 1 h / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 2 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.17 h / 20 °C View Scheme | |
| Multi-step reaction with 3 steps 1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2: sodium hydroxide / 1,4-dioxane; water / pH 11 3: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.17 h / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 4 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C View Scheme | |
| Multi-step reaction with 5 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2.1: sodium hydroxide / 1,4-dioxane; water / pH 11 3.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.5 h / 20 °C 5.2: 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 5 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C 2: piperidine / N,N-dimethyl-formamide / 0.5 h / 20 °C 3: sodium cyanoborohydride; hydrogenchloride / 1,4-dioxane; water / 6 h / 100 °C / pH 3 View Scheme | |
| Multi-step reaction with 3 steps 1.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C 2.1: piperidine / N,N-dimethyl-formamide / 0.5 h / 20 °C 3.1: 1,4-dioxane; water / 1 h / 100 °C 3.2: 20 - 100 °C / pH 3 View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 3 steps 1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 2 h / 20 °C 2: piperidine / N,N-dimethyl-formamide / 0.5 h / 20 °C 3: sodium cyanoborohydride; hydrogenchloride / 1,4-dioxane; water / 4 h / 100 °C / pH 3 View Scheme | |
| Multi-step reaction with 3 steps 1.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 2 h / 20 °C 2.1: piperidine / N,N-dimethyl-formamide / 0.5 h / 20 °C 3.1: 1,4-dioxane; water / 1 h / 100 °C 3.2: 20 - 100 °C / pH 3 View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 20 °C 5.1: dichloromethane / 0.5 h 6.1: sodium cyanoborohydride; hydrogenchloride / 1,4-dioxane; water / 5 h / 100 °C View Scheme | |
| Multi-step reaction with 7 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2.1: sodium hydroxide / 1,4-dioxane; water / pH 11 3.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h / 20 °C 6.1: dichloromethane / 0.5 h 7.1: 1,4-dioxane; water / 1 h / 100 °C 7.2: 4 h / 100 °C / pH 3 View Scheme |
-
-
863971-44-2
(5S,8S,11S,12R)-11-((S)-sec-butyl)-1-(9H fluoren-9-yl)-5,8-diisopropyl-12-methoxy-4,10-dimethyl-3,6,9-trioxo-2-oxa-4,7,10-triazatetradecan-14-oic acid
| Conditions | Yield |
|---|---|
| Multi-step reaction with 6 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 1.2: pH 11 2.1: HATU; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 5 h / 20 °C 3.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 4.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0.5 h / 20 °C 5.1: dichloromethane / 0.5 h / 20 °C 6.1: sodium cyanoborohydride; hydrogenchloride / 1,4-dioxane; water / 5 h / 100 °C View Scheme | |
| Multi-step reaction with 7 steps 1.1: piperidine / N,N-dimethyl-formamide / 0.17 h / 20 °C 2.1: sodium hydroxide / 1,4-dioxane; water / pH 11 3.1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / N,N-dimethyl-formamide / 0.08 h / 20 °C 4.1: palladium 10% on activated carbon; hydrogen / dichloromethane; methanol / 0.5 h / 20 °C 5.1: N-ethyl-N,N-diisopropylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol / N,N-dimethyl-formamide / 0.5 h / 20 °C 6.1: dichloromethane / 0.5 h / 20 °C 7.1: 1,4-dioxane; water / 1 h / 100 °C 7.2: 4 h / 100 °C / pH 3 View Scheme |
Related products
Hot Products
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View