As a leading and professional manufacturer of APIs and API intermediates in China,Anhui Dexinjia Biopharm Co., Ltd founded in 2006, Except for the R&D center, our company has built a close cooperation relation with Chinese Academy of Sciences,
Cas:87120-72-7
Min.Order:1 Kilogram
Negotiable
Type:Manufacturers
inquiryDayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai
Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:87120-72-7
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiry4-Amino-1-Boc-piperidine Basic information Product Name: 4-Amino-1-Boc-piperidine Synonyms: 1-T-BUTOXYCARBONYL-4-AMINOPIPERIDINE;1-tert-Butoxycarbonyl-4-amino-piperidine;1-PIPERIDINECARB
Cas:87120-72-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:87120-72-7
Min.Order:10 Kilogram
Negotiable
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod
Cas:87120-72-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $50.0 / 100.0
Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:87120-72-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry4-Amino-1-Boc-piperidine CAS: 87120-72-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic
Cas:87120-72-7
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:87120-72-7
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry1.high quality: quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed. 2.reasonable price: we provide high quality products with competi
Cas:87120-72-7
Min.Order:10 Gram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Product Name: 4-Amino-1-Boc-piperidine Synonyms: 1-T-BUTOXYCARBONYL-4-AMINOPIPERIDINE;1-tert-Butoxycarbonyl-4-amino-piperidine;1-PIPERIDINECARBOXYLIC ACID, 4-AMINO-,1,1-DIMETHYLETHYL ESTER;1-N-BOC-4-AMINOPIPERIDINE;1-BOC-4-PIPERIDINAMINE;1-BOC-4-
Cas:87120-72-7
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
Cas:87120-72-7
Min.Order:0 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:87120-72-7
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:87120-72-7
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHot sale 87120-72-7 in stock 4-Amino-1-Boc-piperidine good supplier Molecular Formula C10H20N2O2 Molar Mass 200.28 Density 1.041±0.06 g/cm3(Predicted) Melting Point 50°C Boling Poi
Cas:87120-72-7
Min.Order:1 Gram
Negotiable
Type:Other
inquiryChemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff
Cas:87120-72-7
Min.Order:100 Gram
Negotiable
Type:Other
inquiryCompany Profile SHENGZHIKAI TECHNOLOGY INDUSTRY CO., LTD is a high-tech enterprise dedicated to the fields of fine chemical products.The scope of products covers pharmaceutical intermediates, plant extracts, chemical reagent, animal p
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $5.0 / 50.0
Type:Trading Company
inquiryWe are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:87120-72-7
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:10g/bag,or as your request Application:Used for Pesticide intermediates Transport
1. A strong scientific research team . 2. Stable quality (with a complete scientific research center and testing center to ensure the quality stability of each batch of products). 3. Rich export experience (with practical experience in exporting to m
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $8.2 / 8.8
Type:Trading Company
inquiryProduct name: N-Boc-4-Piperidineamine CAS No.: 87120-72-7 Molecule Formula:C10H20N2O2 Molecule Weight:200.28 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard TESTING
Cas:87120-72-7
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developmen
Cas:87120-72-7
Min.Order:1 Kilogram
FOB Price: $2.0 / 6.0
Type:Trading Company
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:87120-72-7
Min.Order:1 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiry4-benzylamino-piperidine-1-carboxylic acid tert-butyl ester
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With hydrogen; palladium 10% on activated carbon In ethanol under 5320.36 Torr; | 98% |
With hydrogen; palladium 10% on activated carbon In ethanol | 98% |
With hydrogen; palladium on activated charcoal In methanol |
tert-butyl 4-(hydroxyimino)piperidine-1-carboxylate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With hydrogen; Raney nickel In ethanol under 2585.81 Torr; | 98% |
With Raney nickel In methanol at 20℃; for 4h; | 83% |
With hydrogen; 5% rhodium on activated aluminium oxide In methanol at 50℃; |
N-tert-butyloxycarbonylpiperidin-4-one
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With hydroxylamine hydrochloride; sodium carbonate In water at 23℃; for 14h; Stage #2: With hydrogen; Raney Ni In ethanol under 2585.81 Torr; for 3.5h; Solid phase; | 96% |
In ammonia-saturated methanol; aluminum nickel | 95.4% |
Stage #1: N-tert-butyloxycarbonylpiperidin-4-one With titanium(IV) isopropylate; ammonia In ethanol at 25℃; for 6h; Stage #2: With sodium tetrahydroborate In ethanol at 25℃; for 3h; Further stages.; | 88% |
A
1,1,1-trifluoroacetophenone
B
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; lithium chloride | A n/a B 90% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; lithium chloride In N,N-dimethyl-formamide at 60℃; for 12h; | 90% |
4-aminopiperidine
di-tert-butyl dicarbonate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: 4-aminopiperidine; di-tert-butyl dicarbonate In 4-methyl-2-pentanone at 0 - 20℃; for 0.5h; Inert atmosphere; Reflux; Stage #2: With water In isopropyl alcohol at 50℃; | 85% |
In dichloromethane at 0℃; for 5h; | 71.9% |
Stage #1: 4-aminopiperidine With benzaldehyde In toluene for 3h; Heating / reflux; Stage #2: di-tert-butyl dicarbonate In toluene at 20℃; | |
With triethylamine In 1,4-dioxane; water | |
With triethylamine In 1,4-dioxane; water |
tert-butyl 4-(2,2,2-trifluoroacetamido)piperidine-1-carboxylate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With ammonium hydroxide In methanol for 2h; Heating; | 81% |
With ammonium hydroxide In methanol for 6h; Heating; | 5.75 g |
With sodium bicarbonate; potassium carbonate In methanol |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With palladium on activated charcoal; hydrogen In methanol at 25℃; for 16h; | 81% |
1,1-dimethylethyl 4-[bis(phenylmethyl)amino]-1-piperidinecarboxylate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With hydrogen; palladium(II) hydroxide In tetrahydrofuran; ethanol at 23℃; under 760.051 Torr; for 6h; Inert atmosphere; | 77% |
tert-butyl 4-azidopiperidine-1-carboxylate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With ammonium hydroxide; triphenylphosphine In 1,4-dioxane; methanol at 27 - 28℃; for 0.5h; | 44% |
With hydrogen; palladium on activated charcoal In methanol under 2068.59 Torr; | |
palladium-carbon In methanol | |
palladium-carbon In methanol; hexane; ethyl acetate |
4-(benzylidene-amino)-piperidine-1-carboxylic acid tert-butyl ester
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With acetic acid for 48h; | 160 mg |
With potassium hydrogensulfate for 1.5h; | 4.76 g |
With sodium hydrogen sulfate; water for 2h; | |
With potassium hydrogensulfate; water In tert-butyl methyl ether at 20℃; for 4h; Inert atmosphere; | 6.0 g |
N-phenylmethylidenepiperidinyl-4-amine
A
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: toluene / 12 h / 25 °C 2: 4.76 g / aq. KHSO4 / 1.5 h View Scheme |
4-aminopiperidine
A
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: toluene / 4 h / Heating 2: toluene / 12 h / 25 °C 3: 4.76 g / aq. KHSO4 / 1.5 h View Scheme |
N-phenylmethylidenepiperidinyl-4-amine
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: Et3N / CH2Cl2 / 48 h / 20 °C 2: 160 mg / aq. AcOH / 48 h View Scheme | |
Multi-step reaction with 2 steps 1: toluene / 14.08 h / 0 - 20 °C / Inert atmosphere 2: potassium hydrogensulfate; water / tert-butyl methyl ether / 4 h / 20 °C / Inert atmosphere View Scheme |
4-aminopiperidine
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: Na2SO4 / CH2Cl2 / 24 h / 20 °C 2: Et3N / CH2Cl2 / 48 h / 20 °C 3: 160 mg / aq. AcOH / 48 h View Scheme | |
Multi-step reaction with 3 steps 1: toluene / 5.5 h / Inert atmosphere; Reflux 2: toluene / 14.08 h / 0 - 20 °C / Inert atmosphere 3: potassium hydrogensulfate; water / tert-butyl methyl ether / 4 h / 20 °C / Inert atmosphere View Scheme |
N-tert-butyloxycarbonylpiperidin-4-one
A
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NaHB(OAc)3 / 1,2-dichloro-ethane 2: H2 / Pd/C / methanol View Scheme |
4-amino-1-benzylpiperidine
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1: 94 percent / Et3N / CH2Cl2 / 12 h / 20 °C 2: H2 / Pd(OH)2/C / methanol / 12 h / 2585.81 Torr 3: CH2Cl2 / 6 h 4: 5.75 g / aq. NH3 / methanol / 6 h / Heating View Scheme | |
Multi-step reaction with 4 steps 1: 94 percent / Et3N / CH2Cl2 / 0.25 h / 0 °C 2: H2 / Pearlman's catalyst / methanol / 48 h / 3102.9 Torr 3: 82 percent / Et3N / CH2Cl2 / 2 h / Ambient temperature 4: 81 percent / 37percent aq. NH4OH / methanol / 2 h / Heating View Scheme |
4-trifluoromethylcarbonylamino piperidine
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: CH2Cl2 / 6 h 2: 5.75 g / aq. NH3 / methanol / 6 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: 82 percent / Et3N / CH2Cl2 / 2 h / Ambient temperature 2: 81 percent / 37percent aq. NH4OH / methanol / 2 h / Heating View Scheme |
N-(1-benzyl-4-piperidinyl)-2,2,2-trifluoroacetamide
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: H2 / Pd(OH)2/C / methanol / 12 h / 2585.81 Torr 2: CH2Cl2 / 6 h 3: 5.75 g / aq. NH3 / methanol / 6 h / Heating View Scheme | |
Multi-step reaction with 3 steps 1: H2 / Pearlman's catalyst / methanol / 48 h / 3102.9 Torr 2: 82 percent / Et3N / CH2Cl2 / 2 h / Ambient temperature 3: 81 percent / 37percent aq. NH4OH / methanol / 2 h / Heating View Scheme |
4-bromo-1H-piperidine
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: DIPEA / CH2Cl2 2: NaN3 / dimethylformamide / 20 °C 3: H2 / 10 percent Pd/C / methanol / 2068.59 Torr View Scheme |
di-tert-butyl dicarbonate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: DIPEA / CH2Cl2 2: NaN3 / dimethylformamide / 20 °C 3: H2 / 10 percent Pd/C / methanol / 2068.59 Torr View Scheme | |
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 16 h / 20 °C 2: palladium on activated charcoal; ammonia; hydrogen / methanol / 20 °C View Scheme |
tert-butyl 4-bromo-1-piperidinecarboxylate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: NaN3 / dimethylformamide / 20 °C 2: H2 / 10 percent Pd/C / methanol / 2068.59 Torr View Scheme |
water
N-tert-butyloxycarbonylpiperidin-4-one
sodium carbonate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
In tetrahydrofuran; EtOH (abs); ethanol | |
In tetrahydrofuran; EtOH (abs); ethanol |
water
N-tert-butyloxycarbonylpiperidin-4-one
sodium carbonate
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
In tetrahydrofuran; EtOH (abs); ethanol | |
In tetrahydrofuran | |
In tetrahydrofuran; EtOH (abs); ethanol |
N-tert-butyloxycarbonylpiperidin-4-one
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With sodium carbonate In tetrahydrofuran; water |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: C17H24N2O2 With potassium hydrogensulfate In water for 1.5h; Stage #2: With potassium hydroxide In water pH=10; |
4-aminopiperidine
di-tert-butyl dicarbonate
benzaldehyde
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: 4-aminopiperidine; benzaldehyde In toluene for 3h; Heating / reflux; Stage #2: di-tert-butyl dicarbonate In toluene at 20℃; |
piperidin-4-one
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: triethylamine / dichloromethane / 16 h / 20 °C 2: palladium on activated charcoal; ammonia; hydrogen / methanol / 20 °C View Scheme |
2-benzthiazole thioacetic acid
1-(tert-butoxycarbonyl)-4-aminopiperidine
N-(1-tert-butoxycarbonylpiperidin-4-yl)-(2-benzothiazolylthio)acetamide
Conditions | Yield |
---|---|
With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In chloroform at 20℃; for 20h; | 100% |
2-chloro-4,6-dimethoxy-1 ,3,5-triazine
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-(4,6-dimethoxy-[1,3,5]triazin-2-ylamino)-piperidine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
In acetonitrile at 160℃; for 0.333333h; microwave irradiation; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
(2-formylthiophen-3-yl)carbamic acid ethyl ester
Conditions | Yield |
---|---|
100% |
2,4-dinitrobenzenesulfonyl chloride
1-(tert-butoxycarbonyl)-4-aminopiperidine
tert-butyl 4-{[(2,4-dinitrophenyl)sulfonyl]amino}piperidine-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: 2,4-dinitrobenzenesulfonyl chloride; 1-(tert-butoxycarbonyl)-4-aminopiperidine With lutidine In dichloromethane at 0 - 20℃; for 18.5h; Stage #2: With potassium hydrogensulfate; water for 0.5h; pH=2.5 - 3; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
2,4-dimethyl-1H-imidazole-5-carbaldehyde
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 0 - 20℃; Cooling with ice; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
chloroacetyl chloride
tert-butyl 4-(2-chloroacetamido)piperidine-1-carboxylate
Conditions | Yield |
---|---|
With triethylamine In dichloromethane at 0 - 20℃; for 1h; | 100% |
With triethylamine In dichloromethane at 0 - 20℃; for 0.333333h; Inert atmosphere; | 90% |
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0 - 20℃; for 0.5h; | 89% |
2,4-dichlorothiazole-5-carboxaldehyde
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-{[(2,4-dichloro-thiazol-5-yl)methyl]-amino}-piperidine-1-carboxylic acid t-butyl ester
Conditions | Yield |
---|---|
Stage #1: 2,4-dichlorothiazole-5-carboxaldehyde; 1-(tert-butoxycarbonyl)-4-aminopiperidine With acetic acid In 1,2-dichloro-ethane at 21 - 26℃; for 1.5h; Stage #2: With sodium tris(acetoxy)borohydride In 1,2-dichloro-ethane at 20 - 27℃; for 4.46667h; | 100% |
With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃; for 18h; | 62% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
2,5(4)-dimethyl-1H-imidazole-4(5)-carboxaldehyde
tert-butyl 4-{[(2,4-dimethyl-1H-imidazol-5-yl)methyl]amino}piperidine-1-carboxylate
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In methanol at 20℃; for 2h; | 100% |
Stage #1: 1-(tert-butoxycarbonyl)-4-aminopiperidine; 2,5(4)-dimethyl-1H-imidazole-4(5)-carboxaldehyde With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃; for 15h; Stage #2: With water; potassium carbonate | 100% |
4-chloro-2-fluoro-nitrobenzene
1-(tert-butoxycarbonyl)-4-aminopiperidine
tert-butyl 4-((5-chloro-2-nitrophenyl)amino)piperidine-1-carboxylate
Conditions | Yield |
---|---|
With sodium carbonate In N,N-dimethyl-formamide at 80℃; for 1h; | 100% |
With sodium carbonate In N,N-dimethyl-formamide at 80℃; for 1h; | 100% |
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 80℃; for 18h; | 93.2% |
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20 - 80℃; for 1h; | |
With potassium carbonate In dimethyl sulfoxide at 20℃; Inert atmosphere; |
4-fluoro-2-methyl-5-nitro-benzonitrile
1-(tert-butoxycarbonyl)-4-aminopiperidine
1,1-dimethylethyl 4-[(4-cyano-5-methyl-2-nitrophenyl)amino]-1-piperidinecarboxylate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 80℃; | 100% |
4-fluoro-3-nitrobenzonitrile
1-(tert-butoxycarbonyl)-4-aminopiperidine
tert-butyl 4-((4-cyano-2-nitrophenyl)amino)piperidine-1-carboxylate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 72h; | 100% |
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 27℃; Cooling with ice; |
methyl 2,4-difluoro-5-nitrobenzoate
1-(tert-butoxycarbonyl)-4-aminopiperidine
tert-butyl 4-{[5-fluoro-4-(methoxycarbonyl)-2-nitrophenyl]amino}piperidine-1-carboxylate
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 72h; | 100% |
4-methyl-benzaldehyde
1-(tert-butoxycarbonyl)-4-aminopiperidine
tert-butyl 4-((4-methylphenyl)methyl)aminopiperidine carboxylate
Conditions | Yield |
---|---|
Stage #1: 4-methyl-benzaldehyde; 1-(tert-butoxycarbonyl)-4-aminopiperidine In ethanol for 4h; Reflux; Stage #2: With sodium tetrahydroborate; ethanol at 20℃; for 24h; | 100% |
Stage #1: 4-methyl-benzaldehyde; 1-(tert-butoxycarbonyl)-4-aminopiperidine In ethanol for 4h; Heating / reflux; Stage #2: With sodium tetrahydroborate In ethanol at 20℃; for 24h; Stage #3: With water In ethanol | 100% |
With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane at 20℃; |
1-(tert-butoxycarbonyl)-4-aminopiperidine
2-methylimidazole-4(5)-carbaldehyde
tert-butyl4-{[(2-methyl-1H-imidazol-5-yl)methyl]amino}piperidine-1-carboxylate
Conditions | Yield |
---|---|
With sodium tris(acetoxy)borohydride; acetic acid In methanol at 20℃; for 2h; | 100% |
3-(Trifluoromethyl)benzenesulfonyl chloride
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-(3-trifluoromethylbenzenesulfonylamino)piperidine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With triethylamine In dichloromethane for 2h; | 100% |
4,6-bis-benzyloxy-5'-isopropyl-2'-methoxybiphenyl-3-carboxylic acid
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-[(4,6-bis-benzyloxy-5'-isopropyl-2'-methoxybiphenyl-3-carbonyl)amino]piperidine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
3,5-ditrifluoromethylisocyanate
tert-butyl 4-(3-(3,5-bis(trifluoromethyl)phenyl)ureido)piperidine-1-carboxylate
Conditions | Yield |
---|---|
In dichloromethane at 20℃; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-Nitrobenzenesulfonyl chloride
4-(4-nitrobenzenesulfonylamino)piperidine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 1h; Inert atmosphere; | 100% |
With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at 20℃; for 1h; Inert atmosphere; |
N-(6-chloro-4-((cis-2,6-dimethylmorpholino)methyl)pyridin-2-yl)thiazolo[5,4-b]pyridin-2-amine
1-(tert-butoxycarbonyl)-4-aminopiperidine
1,1-dimethylethyl 4-{[4-{[cis-2,6-dimethyl-4-morpholinyl]methyl}-6-([1,3]thiazolo[5,4-b]pyridin-2-ylamino)-2-pyridinyl]amino}-1-piperidinecarboxylate
Conditions | Yield |
---|---|
With lithium hexamethyldisilazane; (NHC)Pd(allyl)Cl In tetrahydrofuran at 80℃; for 1h; Microwave irradiation; Inert atmosphere; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
2,4-dibromobutanoyl chloride
tert-butyl 4-(2,4-dibromobutanamido)piperidin-1-carboxylate
Conditions | Yield |
---|---|
Stage #1: 1-(tert-butoxycarbonyl)-4-aminopiperidine; 2,4-dibromobutanoyl chloride With triethylamine In dichloromethane at 0℃; Stage #2: With sodium hydrogencarbonate In dichloromethane Product distribution / selectivity; | 100% |
With triethylamine In tetrahydrofuran at 20℃; for 0.5h; | |
With triethylamine In tetrahydrofuran at 20℃; for 0.5h; |
1-(benzenesulfonyl)-4-chloro-5-nitro-1H-pyrrolo[2,3-b]pyridine
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-(1-benzenesulphonyl-5-nitro-1H-pyrrolo[2,3-b]pyridine-4ylamino)piperidine-1-carboxylic acid tert-butyl ester
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol for 2h; Reflux; | 100% |
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol Inert atmosphere; Heating; |
1-(tert-butoxycarbonyl)-4-aminopiperidine
4-bromobutanenitrile
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile for 48h; Reflux; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
In 1-methyl-pyrrolidin-2-one at 180℃; for 2h; Time; Microwave irradiation; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 15h; Inert atmosphere; | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
5,7-dichloropyrazolo[1,5-a]pyrimidine
Conditions | Yield |
---|---|
With triethylamine In acetonitrile at 100℃; for 12h; | 100% |
With triethylamine In acetonitrile at 100℃; for 12h; |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 15h; | 100% |
2-(4-chloro-3-fluorophenoxy)acetic acid
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: 2-(4-chloro-3-fluorophenoxy)acetic acid; 1-(tert-butoxycarbonyl)-4-aminopiperidine With HATU In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; | 100% |
With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 12h; |
6-chloro-2-quinolinecarboxylic acid
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
Stage #1: 6-chloro-2-quinolinecarboxylic acid; 1-(tert-butoxycarbonyl)-4-aminopiperidine With HATU In N,N-dimethyl-formamide at 20℃; for 0.166667h; Stage #2: With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide | 100% |
1-(tert-butoxycarbonyl)-4-aminopiperidine
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dimethyl sulfoxide at 70℃; for 2h; | 100% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View