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TaiChem Taizhou Limited

Established in May 2015, TaiChem Ltd. is initially invested by a British research and development company and started by PhDs back from aboard. The company is registered in China Medical City (CMC), Taizhou, Jiangsu Province, and the production site

2-(4-Aminopiperidin-1-yl)ethanol

Cas:89850-72-6

Min.Order:10 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

We Huarong Pharm can provide Customized Synthesis & Process R&D & APIs and intermediates Production & Quality Research & Registration Application, especially our GMP validation service which complies with SFDA, FDA, WHO and EU EMPA. O

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

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Type:Trading Company

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SAGECHEM LIMITED

SAGECHEM is a chemical R&D, manufacturing and distribution company in China since 2009, including pharmaceutical intermediates, agrochemical, dyestuff intermediates, organosilicone, API and etc. We also offer a full range of services in

SAGECHEM/ 2-(4-aminopiperidin-1-yl)ethanol /Manufacturer in China

Cas:89850-72-6

Min.Order:0 Metric Ton

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Type:Lab/Research institutions

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Henan Allgreen Chemical Co.,Ltd

high qualityAppearance:white crystalline powder Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

1,3-Phenylenediboronic acid

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Manufacturers

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Xian Changyue Biological Technology Co., Ltd.

best seller Application:API

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Manufacturers

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Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

2-(4-amino-1-piperidinyl)ethanol(SALTDATA: 2HCl)

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

best price high quality Storage:Room Temperature Application:For pharmacy chemicals Transportation:by sea,air

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

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Type:Lab/Research institutions

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DB BIOTECH CO., LTD

best seller Application:API

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

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Type:Trading Company

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Hangzhou Fandachem Co.,Ltd

4-AMINO-1-PIPERIDINEETHANOLCASAppearance:white crystalline powder Storage:Store in dry, dark and ventilated place Package:25KG drum Application:intermediate Transportation:by air, by sea, by express

4-AMINO-1-PIPERIDINEETHANOLCAS

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Other

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Henan Kanbei Chemical Co.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Chinqesen Biotechnology Co., Ltd.

Good Quality Package:1kg/bag Application:Medical or chemical Transportation:Air/Train/Sea Port:Shenzhen

89850-72-6

Cas:89850-72-6

Min.Order:0

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Type:Trading Company

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Hebei Muhuang Technology Co., Ltd

best seller Application:API

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

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Type:Trading Company

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ZHEJIANG JIUZHOU CHEM CO.,LTD

factory?direct?saleAppearance:White powder Storage:Sealed and preserved Package:200/Kilograms Application:healing drugs Transportation:By sea Port:Shanghai/tianjin

4-AMINO-1-PIPERIDINE-ETHANOL

Cas:89850-72-6

Min.Order:0

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Type:Trading Company

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Nanjing Norris Pharm Technology Co., Ltd.

R & D enterprises have their own stock in stockAppearance:To be subject to the object Package:Customized Application:pharmaceutical intermediates Transportation:Air Port:Shanghai;Guangzhou

2-(4-Amino-piperidin-1-yl)-ethanol

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Lab/Research institutions

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NovaChemistry

high purity Application:Drug intermediates Materials intermediates and active molecules

4-Amino-1-piperidineethanol 2HCl

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Trading Company

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BIOFINE

MORE INFORMATION ,PLS CONTAC WITH

1-Piperidineethanol,4-amino-

Cas:89850-72-6

Min.Order:0

Negotiable

Type:Trading Company

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Synthetic route

[1-(2-hydroxyethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester
558443-53-1

[1-(2-hydroxyethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

Conditions
ConditionsYield
With trifluoroacetic acid at 20℃; for 1h;95%
With hydrogenchloride In ethanol; water for 2h; Reflux;95%
With hydrogenchloride In ethanol for 2h; Reflux;95%
Stage #1: [1-(2-hydroxyethyl)-piperidin-4-yl]-carbamic acid tert-butyl ester With trifluoroacetic acid
Stage #2: With hydrogenchloride In methanol at 20℃; for 0.5h;
Stage #3: With sodium hydroxide In water at 20℃; for 0.25h; pH=> 10; Cooling with ice;
87%
Br(1-)*C7H11N2O(1+)
51527-83-4

Br(1-)*C7H11N2O(1+)

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

Conditions
ConditionsYield
Stage #1: Br(1-)*C7H11N2O(1+) With hydrogen; sodium; rhodium contaminated with carbon In methanol at 60℃; under 7240.26 Torr;
Stage #2: In methanol Reflux;
69%
(piperidin-4-yl)carbamic acid tert-butyl ester
73874-95-0

(piperidin-4-yl)carbamic acid tert-butyl ester

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 94 percent / K2CO3 / acetonitrile / 5 h / Heating
2: 95 percent / TFA / 1 h / 20 °C
View Scheme
Multi-step reaction with 2 steps
1.1: potassium carbonate / acetonitrile / 5 h / Reflux
2.1: trifluoroacetic acid
2.2: 0.5 h / 20 °C
2.3: 0.25 h / 20 °C / pH > 10 / Cooling with ice
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 5 h / Reflux
2: hydrogenchloride / ethanol; water / 2 h / Reflux
View Scheme
Multi-step reaction with 2 steps
1: potassium carbonate / acetonitrile / 5 h / Reflux
2: hydrogenchloride / ethanol / 2 h / Reflux
View Scheme
4-aminopyridine
504-24-5

4-aminopyridine

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: toluene / 3.5 h / Reflux
2.1: hydrogen; sodium / rhodium contaminated with carbon / methanol / 60 °C / 7240.26 Torr
2.2: Amberlyst 15 resin / Reflux
View Scheme
2,6-dichloro-N-(2-ethylhexyl)nicotinamide
1421000-02-3

2,6-dichloro-N-(2-ethylhexyl)nicotinamide

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

6-chloro-N-(2-ethylhexyl)-2-{[1-(2-hydroxyethyl)piperidin-4-yl]amino}nicotinamide
1420999-78-5

6-chloro-N-(2-ethylhexyl)-2-{[1-(2-hydroxyethyl)piperidin-4-yl]amino}nicotinamide

Conditions
ConditionsYield
With potassium carbonate In o-xylene for 24h; Reflux;77.9%
With potassium carbonate In o-xylene for 24h; Reflux;77.9%
4-iodobenzoic acid
619-58-9

4-iodobenzoic acid

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

C14H19IN2O2

C14H19IN2O2

Conditions
ConditionsYield
With 4-methyl-morpholine; 1-hydroxybenzotriazol-hydrate; triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 20h;50%
4-Bromobenzoic acid
586-76-5

4-Bromobenzoic acid

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

4-bromo-N-(1-(2-hydroxyethyl)piperidin-4-yl)benzamide

4-bromo-N-(1-(2-hydroxyethyl)piperidin-4-yl)benzamide

Conditions
ConditionsYield
With 4-methyl-morpholine; 1-hydroxybenzotriazol-hydrate; triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 20℃; for 20h;40%
(R)-1-(3-((3'-(3-bromopropoxy)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)oxy)propyl)pyrrolidin-3-ol

(R)-1-(3-((3'-(3-bromopropoxy)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)oxy)propyl)pyrrolidin-3-ol

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

(R)-1-(3-((3'-(3-((1-(2-hydroxyethyl)piperidin-4-yl)amino)propoxy)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)oxy)propyl)pyrrolidin-3-ol

(R)-1-(3-((3'-(3-((1-(2-hydroxyethyl)piperidin-4-yl)amino)propoxy)-2,2'-dimethyl-[1,1'-biphenyl]-3-yl)oxy)propyl)pyrrolidin-3-ol

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In methanol at 65℃; for 72h; Inert atmosphere;34%
7-bromo-2-chloroquinoxaline
89891-65-6

7-bromo-2-chloroquinoxaline

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

C15H19BrN4O
1345444-82-7

C15H19BrN4O

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 100℃; for 24h;32%
With N-ethyl-N,N-diisopropylamine In isopropyl alcohol at 100℃; for 24h;32%
4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

1H-1,2,3-benzotriazol-1-yl 4-amino-3-methoxybenzoate

1H-1,2,3-benzotriazol-1-yl 4-amino-3-methoxybenzoate

4-amino-N-[1-(2-hydroxy-ethyl)-piperidin-4-yl]-3-methoxy-benzamide
1201694-09-8

4-amino-N-[1-(2-hydroxy-ethyl)-piperidin-4-yl]-3-methoxy-benzamide

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide
7-bromo-2-chloroquinoxaline
89891-65-6

7-bromo-2-chloroquinoxaline

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

C30H29F2N7O3
1345437-78-6

C30H29F2N7O3

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 24 h / 100 °C
2: N-ethyl-N,N-diisopropylamine; copper(l) iodide / [Pd0(1,1’-bis(diphenylphosphino)ferrocene)] / dimethyl sulfoxide / 3 h / 90 °C
View Scheme
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / isopropyl alcohol / 24 h / 100 °C
2: N-ethyl-N,N-diisopropylamine / dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; copper(l) iodide / dimethyl sulfoxide / 3 h / 90 °C
View Scheme
2,6-dichloropyrazine
4774-14-5

2,6-dichloropyrazine

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

2-(4-((6-chloropyrazin-2-yl)amino)piperidin-1-yl)ethanol
1401732-37-3

2-(4-((6-chloropyrazin-2-yl)amino)piperidin-1-yl)ethanol

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 100℃; Inert atmosphere;
4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

2-(4-((6-(1-(4-methoxybenzyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrazin-2-yl)amino)piperidin-1-yl)ethanol
1401732-38-4

2-(4-((6-(1-(4-methoxybenzyl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrazin-2-yl)amino)piperidin-1-yl)ethanol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 100 °C / Inert atmosphere
2: potassium tert-butylate / 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 12 h / 80 °C / Inert atmosphere
View Scheme
4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

2-(4-((6-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrazin-2-yl)amino)piperidin-1-yl)ethanol
1401731-27-8

2-(4-((6-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyrazin-2-yl)amino)piperidin-1-yl)ethanol

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 100 °C / Inert atmosphere
2.1: potassium tert-butylate / 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; tris-(dibenzylideneacetone)dipalladium(0) / 1,4-dioxane / 12 h / 80 °C / Inert atmosphere
3.1: trifluoroacetic acid / chloroform / 50 °C
3.2: pH 8
View Scheme
3,3-dimethyl-5-oxo-5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-(2-oxoethyl)-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)pentanoic acid
1025068-57-8

3,3-dimethyl-5-oxo-5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-(2-oxoethyl)-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)pentanoic acid

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(2-((1-(2-hydroxyethyl)piperidin-4-yl)amino)ethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)-3,3-dimethyl-5-oxopentanoic acid

5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-(2-((1-(2-hydroxyethyl)piperidin-4-yl)amino)ethyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)-3,3-dimethyl-5-oxopentanoic acid

Conditions
ConditionsYield
With sodium tris(acetoxy)borohydride; acetic acid In dichloromethane at 20℃;
3,3-dimethyl-5-oxo-5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-(2-oxoethyl)-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)pentanoic acid
1025068-57-8

3,3-dimethyl-5-oxo-5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-(2-oxoethyl)-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)pentanoic acid

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

trifluoroacetic acid
76-05-1

trifluoroacetic acid

(3β)-17-[2-[[1-(2-hydroxyethyl)piperidin-4-yl]amino]ethyl]-28-norIup-20(29)-en-3-ol 3-(hydrogen 3,3-dimethyIpentanedioate) bis(trifluoroacetate)

(3β)-17-[2-[[1-(2-hydroxyethyl)piperidin-4-yl]amino]ethyl]-28-norIup-20(29)-en-3-ol 3-(hydrogen 3,3-dimethyIpentanedioate) bis(trifluoroacetate)

Conditions
ConditionsYield
Stage #1: 3,3-dimethyl-5-oxo-5-(((1R,3aR,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-(2-oxoethyl)-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-9-yl)oxy)pentanoic acid; 4-amino-1-(2-hydroxyethyl)piperidine With sodium tris(acetoxy)borohydride; acetic acid In 1,2-dichloro-ethane for 18h;
Stage #2: trifluoroacetic acid
phenyl ((1R,4R)-4-((4-((5-cyclopentyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)cyclohexyl)carbamate

phenyl ((1R,4R)-4-((4-((5-cyclopentyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)cyclohexyl)carbamate

4-amino-1-(2-hydroxyethyl)piperidine
89850-72-6

4-amino-1-(2-hydroxyethyl)piperidine

trifluoroacetic acid
76-05-1

trifluoroacetic acid

1-((1R,4R)-4-((4-((5-cyclopentyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)cyclohexyl)-3-(1-(2-hydroxyethyl)piperidin-4-yl)urea 2,2,2-trifluoroacetate

1-((1R,4R)-4-((4-((5-cyclopentyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)cyclohexyl)-3-(1-(2-hydroxyethyl)piperidin-4-yl)urea 2,2,2-trifluoroacetate

Conditions
ConditionsYield
Stage #1: phenyl ((1R,4R)-4-((4-((5-cyclopentyl-1H-pyrazol-3-yl)amino)pyrimidin-2-yl)amino)cyclohexyl)carbamate With triethylamine In N,N-dimethyl-formamide at 85℃; for 1h;
Stage #2: 4-amino-1-(2-hydroxyethyl)piperidine In N,N-dimethyl-formamide at 95℃; for 16h;
Stage #3: trifluoroacetic acid
25 mg

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