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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

4-Trifluoromethylbenzyl chloride

Cas:939-99-1

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 4-(Trifluoromethyl)Benzyl Chloride

Cas:939-99-1

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

huge stock TC Insecticide 4-Trifluoromethylbenzyl chloride 939-99-1 GLP Manufacturer

Cas:939-99-1

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

4-(Trifluoromethyl)benzyl chloride

Cas:939-99-1

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

4-(Trifluoromethyl)Benzyl Chloride

Cas:939-99-1

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

4-(Trifluoromethyl)-benzyl chloride

Cas:939-99-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be sent out in 24 hours after payment.Tracking number available 2) Secure and disc

4-Trifluoromethylbenzyl chloride CAS:939-99-1

Cas:939-99-1

Min.Order:1 Kilogram

FOB Price: $150.0 / 200.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 939-99-1 with best quality

Cas:939-99-1

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ

Benzene,1-(chloromethyl)-4-(trifluoromethyl)-

Cas:939-99-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Benzene,1-(chloromethyl)-4-(trifluoromethyl)-

Cas:939-99-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:939-99-1

Cas:939-99-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

4-(Trifluoromethyl)benzyl Chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzene,1-(chloromethyl)-4-(trifluoromethyl)-

Cas:939-99-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

High Quality Best price Fast Delivery Good Service Welcome to Henan Tianfu Chemical Co., Ltd. website. Our company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; developm

4-Trifluoromethylbenzyl chloride

Cas:939-99-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Siwei Development Group Ltd.

Product name: 4-(Trifluoromethyl)benzyl Chloride CAS No.: 939-99-1 Molecule Formula:C8H6ClF3 Molecule Weight:194.58 Purity: 99.0% Package: 25kg/drum Description:White crystalline powder Manufacture Standards:Enterprise Standard

Lower Price 4-(Trifluoromethyl)benzyl Chloride

Cas:939-99-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shanghai Minstar Chemical Co., Ltd

4-Trifluoromethylbenzyl chloride Basic information Product Name: 4-Trifluoromethylbenzyl chloride Synonyms: TIMTEC-BB SBB006696;P-(TRIFLUOROMETHYL)BENZYL CHLORIDE;1-(CHLOROMETHYL)-4-(TRIFLUOROMETHYL)BENZENE;ALPHA'-CHLORO-ALPHA,ALPHA,ALPHA-TRIFLU

4-(Trifluoromethyl)benzyl chloride

Cas:939-99-1

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

TAIZHOU ZHENYU BIOTECHNOLOGY CO., LTD

Zhenyu biotech exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, zhenyu biotech is your best choice. pls contact with us freely for getting detailed

4-Trifluoromethylbenzyl chloride

Cas:939-99-1

Min.Order:1 Kilogram

FOB Price: $2.0

Type:Lab/Research institutions

inquiry

Hangzhou Fandachem Co.,Ltd

Hangzhou Fanda Chemical Co.,Ltd (FandaChem) , a China-based chemical company, specialize in exporting 4-Trifluoromethylbenzyl chloride CAS:939-99-1 , Please contact us by email freely. We are leading exporter in China. If you really n

4-Trifluoromethylbenzyl chloride CAS:939-99-1 from Fandachem

Cas:939-99-1

Min.Order:0 Metric Ton

Negotiable

Type:Other

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KAISA GROUP INC

1.Applied in food field.it can improve the immune system and prolong life. 2.Appliedin cosmetic field.it can improve the skin care. 3.Applied in pharmaceutical field.it can treat various dieases. 4.Our product quality assurance will make our customer

939-99-1 CAS NO.939-99-1

Cas:939-99-1

Min.Order:1 Metric Ton

FOB Price: $7.0 / 8.0

Type:Trading Company

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Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

4-Trifluoromethylbenzyl chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Golden Pharma Co., Limited

GOLDEN PHARMA CO.,LIMITED.is a professional pharmaceutical company,our team have more than 20years expereince in pharmaceutical production and sales. we are a professional technical enterprise specializing in the R & D, production,QA regulation

4-(Trifluoromethyl)benzyl chloride

Cas:939-99-1

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Win-Win chemical Co.Ltd

Stock products, own laboratory Package:Grams, Kilograms Application:For R&D Transportation:According to customer request Port:Shanghai

4-(Trifluoromethyl)benzyl chloride cas no. 939-99-1 98%

Cas:939-99-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

4-(Trifluoromethyl)benzyl chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,Pharmaceutical intermediates Transportation:air,sea,courier

4-(Trifluoromethyl)benzyl chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

P-Trifluoromethyl Benzyl Chloride

Cas:939-99-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Hangzhou Dingyan Chem is a leading manufacturer and supplier of chemicals in China.We develop,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quality in your re

4-trifluoromethylbenzyl chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Acmec Biochemical Technology Co., Ltd.

Acmec is a leading manufacturer and supplier of biochemical reagents and life science products. We have over 40,000 items in stock (real-time inventory) and offer discounted prices to registered members of the online store ( www.acmec.com.cn ) Appea

Acmec 4-(Trifluoromethoxy)benzylchloride 100g

Cas:939-99-1

Min.Order:1 bottle

Negotiable

Type:Lab/Research institutions

inquiry

Henan Allgreen Chemical Co.,Ltd

high quality Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea

4-Trifluoromethylbenzyl chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

4-(Trifluoromethyl)Benzyl Chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Hubei Taiho Chemical Co.,LTD

TAIHO Unique Advantages:1.We're factory2.Free samples available3.Commodity inspection can be done4.ISO9001,Kosher certifications5.10 years experiences Storage:Store in cool &dry place Package:aluminium foil bag/fiber can/plastic drum Application:comp

4-(Trifluoromethyl)benzyl chloride

Cas:939-99-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Synthetic route

4-methylbenzotrifluoride
6140-17-6

4-methylbenzotrifluoride

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
With N-chloro-succinimide; N-hydroxyphthalimide; 2,3-dicyano-5,6-dichloro-p-benzoquinone In acetonitrile at 80℃; for 16h; Time; Sealed tube; Inert atmosphere;87%
With hypochlorous anhydride In tetrachloromethane at 25℃; relative rate constant;
4-(trifluoromethyl)benzylic alcohol
349-95-1

4-(trifluoromethyl)benzylic alcohol

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 70℃; for 1.08333h;86.7%
With 1-pyrrolidinecarboxaldehyde; benzoyl chloride In 1,4-dioxane at 20℃; for 24h; Sealed tube;85%
With tetra-(n-butyl)ammonium iodide; 1,2-dichloro-ethane; triphenylphosphine at 120℃; for 0.5h; Sealed tube; Inert atmosphere;82%
4-(trifluoromethyl)benzylic alcohol
349-95-1

4-(trifluoromethyl)benzylic alcohol

Benzotrichlorid
98-07-7

Benzotrichlorid

A

benzylidene dichloride
98-87-3

benzylidene dichloride

B

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
With TOP; phenylsilane In neat (no solvent) at 100℃; for 24h; Appel Halogenation; Inert atmosphere;A n/a
B 69%
4-trifluoromethylbenzoic acid
455-24-3

4-trifluoromethylbenzoic acid

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
With gallium(III) trichloride; Hexamethyldisiloxane; copper dichloride In 1,2-dichloro-ethane at 20℃; for 5h; Sealed tube; Inert atmosphere;33%
Multi-step reaction with 2 steps
1: LiAlH4 / diethyl ether
2: SOCl2
View Scheme
Multi-step reaction with 2 steps
1: LiAlH4
2: SOCl2
View Scheme
1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene
81577-13-1

1-(1-Chloro-2,2,2-trifluoro-ethyl)-4-fluoro-benzene

C8H6F3(1+)
109418-80-6

C8H6F3(1+)

A

C8H5F4(1+)
128408-32-2

C8H5F4(1+)

B

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
at 69.85℃; Thermodynamic data; chloride-transfer;
C9H6ClF3O

C9H6ClF3O

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
In 1,2-dichloro-ethane at 25℃; Kinetics;
4-(trifluoromethyl)benzylic alcohol
349-95-1

4-(trifluoromethyl)benzylic alcohol

A

bis(p-trifluoromethylbenzyl) sulfite
1396318-77-6

bis(p-trifluoromethylbenzyl) sulfite

B

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
With pyridine; thionyl chloride In dichloromethaneA 8.8 %Spectr.
B 5.8 %Spectr.
4-Trifluoromethylbenzaldehyde
455-19-6

4-Trifluoromethylbenzaldehyde

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: sodium tetrahydroborate; methanol / 0.5 h / 0 °C
2: thionyl chloride / 1.08 h / 0 - 70 °C
View Scheme
1,4-diaza-bicyclo[2.2.2]octane
280-57-9

1,4-diaza-bicyclo[2.2.2]octane

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-(4-(trifluoromethyl)benzyl)-4-aza-1-azonia-bicyclo[2.2.2]octane chloride

1-(4-(trifluoromethyl)benzyl)-4-aza-1-azonia-bicyclo[2.2.2]octane chloride

Conditions
ConditionsYield
In tetrahydrofuran for 2h; Heating;100%
In tetrahydrofuran at 20℃; for 12h;92%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

C61H57F9N2O6(2+)*2Cl(1-)

C61H57F9N2O6(2+)*2Cl(1-)

Conditions
ConditionsYield
With triethylhexadecylammonium chloride In water at 200℃; for 0.1h; Reagent/catalyst; Solvent; Temperature; Microwave irradiation;97.11%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

2-hydroxy-4-(methoxymethyloxy)benzaldehyde
95332-26-6

2-hydroxy-4-(methoxymethyloxy)benzaldehyde

4-methoxymethoxy-2-[4-(trifluoromethyl)benzyloxy]benzaldehyde
1257999-32-8

4-methoxymethoxy-2-[4-(trifluoromethyl)benzyloxy]benzaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 3h;96%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

phenol
108-95-2

phenol

1-(phenoxymethyl)-4-(trifluoromethyl)benzene
19962-24-4

1-(phenoxymethyl)-4-(trifluoromethyl)benzene

Conditions
ConditionsYield
With potassium carbonate In acetone94.2%
4-methoxyphenylboronic acid
5720-07-0

4-methoxyphenylboronic acid

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-(4-methoxybenzyl)-4-(trifluoromethyl)-benzene

1-(4-methoxybenzyl)-4-(trifluoromethyl)-benzene

Conditions
ConditionsYield
With dichloro bis(acetonitrile) palladium(II); 1,3-bis(diphenylphosphino)-1H-indole; sodium hydroxide In N,N-dimethyl acetamide at 120℃; for 6h; Reagent/catalyst; Suzuki-Miyaura Coupling; Inert atmosphere;94%
With C36H49Cl2N3Pd; sodium t-butanolate In ethanol at 50℃; for 1h; Suzuki-Miyaura Coupling; Sealed tube;70 %Chromat.
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

4-(2-(diphenylmethoxy)ethyl]piperidine
204064-81-3

4-(2-(diphenylmethoxy)ethyl]piperidine

4-[2-(diphenylmethoxy)ethyl]-1-[((4-trifluoromethyl)phenyl)methyl]piperidine
333363-98-7

4-[2-(diphenylmethoxy)ethyl]-1-[((4-trifluoromethyl)phenyl)methyl]piperidine

Conditions
ConditionsYield
With potassium carbonate; triethylamine In N,N-dimethyl-formamide at 65℃;92%
With potassium carbonate; triethylamine In DMF (N,N-dimethyl-formamide)92%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-(4-bromophenyl)-1H-tetrazole-5-thiol
22347-29-1

1-(4-bromophenyl)-1H-tetrazole-5-thiol

1-(4-bromo-phenyl)-5-(4-trifluoromethyl-benzylsulfanyl)-1H-tetrazole

1-(4-bromo-phenyl)-5-(4-trifluoromethyl-benzylsulfanyl)-1H-tetrazole

Conditions
ConditionsYield
With potassium hydroxide; tetrabutylammomium bromide In toluene Heating;92%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

4-benzoxy-salicylaldehyde
52085-14-0

4-benzoxy-salicylaldehyde

4-benzyloxy-2-[4-(trifluoromethyl)benzyloxy]benzaldehyde
1257999-13-5

4-benzyloxy-2-[4-(trifluoromethyl)benzyloxy]benzaldehyde

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 90℃; for 3h;92%
Pentafluorobenzene
363-72-4

Pentafluorobenzene

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1,2,3,4,5-pentafluoro-6-(4-(trifluoromethyl)benzyl)benzene
1234340-47-6

1,2,3,4,5-pentafluoro-6-(4-(trifluoromethyl)benzyl)benzene

Conditions
ConditionsYield
With palladium diacetate; caesium carbonate; triphenylphosphine; Trimethylacetic acid In toluene at 140℃; for 12h; Inert atmosphere;91%
N-methylacetohydroxamic acid
13115-24-7

N-methylacetohydroxamic acid

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

N-methyl-N-((4-(trifluoromethyl)benzyl)oxy)acetamide
1352918-97-8

N-methyl-N-((4-(trifluoromethyl)benzyl)oxy)acetamide

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide; mineral oil at 0 - 20℃; for 12h; Inert atmosphere;91%
1-(2-hydroxyphenyl)-imidazole
10041-04-0

1-(2-hydroxyphenyl)-imidazole

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

C17H14F3N2O(1+)*Cl(1-)

C17H14F3N2O(1+)*Cl(1-)

Conditions
ConditionsYield
In acetonitrile for 4h; Reflux;91%
carbon dioxide
124-38-9

carbon dioxide

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

A

4-methylbenzotrifluoride
6140-17-6

4-methylbenzotrifluoride

B

4-Trifluoromethylphenylacetic acid
32857-62-8

4-Trifluoromethylphenylacetic acid

Conditions
ConditionsYield
With salcomine; tetrabutylammonium perchlorate; water In acetonitrile at 25℃; electrochemical reaction;A 90.5%
B 3.3%
With salcomine; tetrabutylammonium perchlorate In acetonitrile at 25℃; electrochemical reaction;A 13.8%
B 84.3%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

2-mercapto-5-methylbenzimidazole
27231-36-3

2-mercapto-5-methylbenzimidazole

6-methyl-2-(4-trifluoromethyl-benzylsulfanyl)-1H-benzoimidazole

6-methyl-2-(4-trifluoromethyl-benzylsulfanyl)-1H-benzoimidazole

Conditions
ConditionsYield
Stage #1: 2-mercapto-5-methylbenzimidazole With sodium methylate In methanol; N,N-dimethyl-formamide at 20℃; for 0.166667h;
Stage #2: 4-trifluoromethylbenzyl chloride In methanol; N,N-dimethyl-formamide at 20℃;
90%
1-(4-methylphenyl)tetrazole-5-thiol
13980-77-3

1-(4-methylphenyl)tetrazole-5-thiol

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-p-tolyl-5-(4-trifluoromethyl-benzylsulfanyl)-1H-tetrazole

1-p-tolyl-5-(4-trifluoromethyl-benzylsulfanyl)-1H-tetrazole

Conditions
ConditionsYield
With potassium hydroxide; tetrabutylammomium bromide In toluene Heating;90%
3-[2-hydroxy-4-(2-methoxyethoxy)phenyl]propanoic acid ethyl ester
888740-22-5

3-[2-hydroxy-4-(2-methoxyethoxy)phenyl]propanoic acid ethyl ester

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

3-(4-(2-methoxyethoxy)-2-{[4-(trifluoromethyl)benzyl]oxy}phenyl)propanoic acid ethyl ester
888740-72-5

3-(4-(2-methoxyethoxy)-2-{[4-(trifluoromethyl)benzyl]oxy}phenyl)propanoic acid ethyl ester

Conditions
ConditionsYield
In N,N-dimethyl-formamide90%
Stage #1: 3-[2-hydroxy-4-(2-methoxyethoxy)phenyl]propanoic acid ethyl ester With sodium hydride In N,N-dimethyl-formamide for 0.5h;
Stage #2: 4-trifluoromethylbenzyl chloride In N,N-dimethyl-formamide for 2h;
90%
C11H15F2NO2

C11H15F2NO2

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

4-(2,2-difluoroethylamino)-3-[4-(trifluoromethyl)benzyl]-1-oxaspiro[4.5]dec-3-en-2-one

4-(2,2-difluoroethylamino)-3-[4-(trifluoromethyl)benzyl]-1-oxaspiro[4.5]dec-3-en-2-one

Conditions
ConditionsYield
Stage #1: C11H15F2NO2 With caesium carbonate In acetonitrile at 0 - 20℃; for 4h;
Stage #2: 4-trifluoromethylbenzyl chloride In acetonitrile for 12h; Reflux; regioselective reaction;
89%
anthranil
271-58-9

anthranil

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

molybdenum hexacarbonyl
13939-06-5, 199620-15-0

molybdenum hexacarbonyl

3-(4-(trifluoromethyl)phenyl)quinolin-2(1H)-one

3-(4-(trifluoromethyl)phenyl)quinolin-2(1H)-one

Conditions
ConditionsYield
With water; palladium diacetate; (S)-(1,1'-binaphthalene)-2,2'-diylbis(diphenylphosphine); triethylamine In 1,2-dimethoxyethane at 100℃; for 26h; Sealed tube; Inert atmosphere;89%
2-(4-fluorophenyl)-2-(N,N-dimethylamino)acetonitrile

2-(4-fluorophenyl)-2-(N,N-dimethylamino)acetonitrile

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-(4-fluorophenyl)-2-(4-trifluoromethylphenyl)-N,N-dimethylethenylamine

1-(4-fluorophenyl)-2-(4-trifluoromethylphenyl)-N,N-dimethylethenylamine

Conditions
ConditionsYield
With sodium hydride In DMF (N,N-dimethyl-formamide) at 5 - 30℃; for 2h;88.3%
allylmagnesium bromide
2622-05-1

allylmagnesium bromide

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-(but-3-en-1-yl)-4-(trifluoromethyl)benzene

1-(but-3-en-1-yl)-4-(trifluoromethyl)benzene

Conditions
ConditionsYield
In diethyl ether for 16h; Condensation; Heating;88%
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

N-(4-chloro-2-mercapto-5-methylbenzenesulfonyl)cyanamide dipotassium salt

N-(4-chloro-2-mercapto-5-methylbenzenesulfonyl)cyanamide dipotassium salt

N-{4-chloro-5-methyl-2-[(4-trifluoromethylbenzyl)thio]benzenesulfonyl}cyanamide potassium salt

N-{4-chloro-5-methyl-2-[(4-trifluoromethylbenzyl)thio]benzenesulfonyl}cyanamide potassium salt

Conditions
ConditionsYield
In ethanol at 20℃; for 4h;88%
at 20℃;
piperazine
110-85-0

piperazine

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-(4-trifluoromethylbenzyl)piperazine
107890-32-4

1-(4-trifluoromethylbenzyl)piperazine

Conditions
ConditionsYield
In tetrahydrofuran for 4h; Reflux; Inert atmosphere;88%
In dichloromethane at 0 - 20℃; for 6h;
In dichloromethane at 0℃;
4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

N,N-dimethyl (trimethylsilyl)methanamide
479486-96-9

N,N-dimethyl (trimethylsilyl)methanamide

N,N-dimethyl-2-(4-(trifluoromethyl)phenyl)acetamide
869337-11-1

N,N-dimethyl-2-(4-(trifluoromethyl)phenyl)acetamide

Conditions
ConditionsYield
tetrakis(triphenylphosphine) palladium(0) In toluene at 100℃; for 1h;87%
Thiomorpholine-4-carbodithioate sodium salt

Thiomorpholine-4-carbodithioate sodium salt

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

4-(trifluoromethyl)benzyl thiomorpholine-4-carbodithioate
1498922-64-7

4-(trifluoromethyl)benzyl thiomorpholine-4-carbodithioate

Conditions
ConditionsYield
In acetone at 20℃; for 3h;87%
2-phenylpropane-1, 3-diol
1570-95-2

2-phenylpropane-1, 3-diol

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

(S)-2-phenyl-3-(p-trifluoromethylbenzyloxy)propan-1-ol

(S)-2-phenyl-3-(p-trifluoromethylbenzyloxy)propan-1-ol

Conditions
ConditionsYield
With (R)-2,4-dimethyl-7-(2-(trityloxy)naphthalen-1-yl)-5H-benzo[c]naphtho[2,3-e][1,2]oxaborinin-5-ol; potassium carbonate; potassium iodide In acetonitrile at 20℃; for 24h; Sealed tube; enantioselective reaction;87%
2-Mercaptobenzothiazole
149-30-4

2-Mercaptobenzothiazole

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

2-((4-(trifluoromethyl)benzyl)thio)benzo[d]thiazole
758716-82-4

2-((4-(trifluoromethyl)benzyl)thio)benzo[d]thiazole

Conditions
ConditionsYield
With potassium hydroxide In water at 50℃; for 0.5h; Sealed tube; Green chemistry;86%
With potassium carbonate In water at 50℃; for 0.5h; Solvent; Sealed tube; Green chemistry;
1-benzyl-4-(4-fluorophenyl)piperidin-3-one oxime
1280635-01-9

1-benzyl-4-(4-fluorophenyl)piperidin-3-one oxime

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

(Z)-1-benzyl-4-(4-fluorophenyl)piperidin-3-one O-4-trifluoromethylbenzyl oxime
1280635-08-6

(Z)-1-benzyl-4-(4-fluorophenyl)piperidin-3-one O-4-trifluoromethylbenzyl oxime

Conditions
ConditionsYield
Stage #1: 1-benzyl-4-(4-fluorophenyl)piperidin-3-one oxime With sodium hydride In tetrahydrofuran at 20℃; for 1h;
Stage #2: 4-trifluoromethylbenzyl chloride In N,N-dimethyl-formamide at 50℃; for 120h;
85%
sodium N-morpholinocarbamodithioate
873-58-5

sodium N-morpholinocarbamodithioate

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

4-(trifluoromethyl)benzyl morpholine-4-carbodithioate
1498922-66-9

4-(trifluoromethyl)benzyl morpholine-4-carbodithioate

Conditions
ConditionsYield
In acetone at 20℃; for 3h;85%
2-(3-methoxyphenyl)-5, 5-dimethyl-1,3,2-dioxaborinane
1003858-50-1

2-(3-methoxyphenyl)-5, 5-dimethyl-1,3,2-dioxaborinane

4-trifluoromethylbenzyl chloride
939-99-1

4-trifluoromethylbenzyl chloride

1-methoxy-3-(4-(trifluoromethyl)benzyl)benzene

1-methoxy-3-(4-(trifluoromethyl)benzyl)benzene

Conditions
ConditionsYield
With 1-methyl-2-azepanone; copper(l) iodide; 2,2,6,6-tetramethylheptane-3,5-dione; lithium tert-butoxide at 60℃; for 12h; Suzuki-Miyaura Coupling; Schlenk technique; Inert atmosphere;85%

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