497937-79-8

Basic information

• Product Name: N-trifluoromethanesulfinyl-O-trimethylsilylephedrine
• Synonyms: N-trifluoromethanesulfinyl-O-trimethylsilylephedrine
• CAS NO: 497937-79-8
• Molecular Weight: 353.481
• Mol File: 497937-79-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-trifluoromethanesulfinyl-O-trimethylsilylephedrine(CAS DataBase Reference)
• NIST Chemistry Reference: N-trifluoromethanesulfinyl-O-trimethylsilylephedrine(497937-79-8)
• EPA Substance Registry System: N-trifluoromethanesulfinyl-O-trimethylsilylephedrine(497937-79-8)

Safety Data

• Hazardous Substances Data: 497937-79-8(Hazardous Substances Data)

Upstream product

• 299-42-3 ephedrine 
• 67069-59-4 N-methyl-[(1S,2R)-(2-phenyl-1-methyl-2-trimethylsilyloxy)]ethylamine 
• 41804-89-1 potassium triflinate 

Downstream Products

• 124898-12-0 trimethyl[(2,2,2-trifluoro-1-phenylethoxy)]silane 
• 228123-21-5 trimethyl[[(2E)-3-phenyl-1-(trifluoromethyl)-2-propenyl]oxy]silane 
• 208331-49-1 (E)-trimethyl((1,1,1-trifluoro-2,4-diphenylbut-3-en-2-yl)oxy)silane 
• 228123-22-6 trimethyl-(2,2,2-trifluoro-1-methyl-1-phenyl-ethoxy)-silane 
• 208331-51-5 (E,E)-3-trifluoromethyl-3-trimethylsilyloxy-1,5-diphenyl-1,4-pentadiene 
• 118143-24-1 2,2,2-trifluoro-1,1-diphenyl-1-(trimethylsilyloxy)ethane 

Relevant articles and documents

Towards enantioselective nucleophilic trifluoromethylation

Various trifluoroacetamides and trifluoromethanesulfinamides, derived from chiral silylated amino alcohols, have been synthesized with the goal of achieving enantioselective nucleophilic trifluoromethylation. The best results were obtained with (R)-phenylglycinol derivatives, but the ee values did not exceed 30%.