Carbenicillin sodium;4800-94-6;Carbenicillin disodium salt;Carbenicillin sodium usage;Carbenicillin sodium Toxicity

NANJING AILY BIOTECHNOLOGY CO.,LTD

Country:China (Mainland)

Year Established: Business type: Lab/Research institutions

Integral:

Carbenicillin sodium, with its CAS registry number 4800-94-6, could also be called as Carbenicillin disodium salt or carbenicillin disodium. With its Molecular formula of C₁₇H₁₆N₂Na₂O₆S and molecular weight of 422.36, Carbenicillin sodium is one kind of white solid, and it is stable under normal temperature and pressure. As to Carbenicillin sodium solubility, it is soluble in water. Besides, its Classification Code are Antibacterial and Drug / Therapeutic Agent.

When comes to Carbenicillin sodium usage, it could be applied as broad-spectrum semisynthetic penicillin derivative used parenterally. It is susceptible to gastric juice and penicillinase and may damage platelet function. If you want to store it, you should keep sealed in dry, cool and well-ventilated place, away from light and heat.

Carbenicillin sodium Toxicity detailed information are as below.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	intravenous	> 4gm/kg (4000mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
dog	LD50	subcutaneous	> 4gm/kg (4000mg/kg)	GASTROINTESTINAL: NAUSEA OR VOMITING	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
monkey	LD50	intravenous	9800mg/kg (9800mg/kg)	LUNGS, THORAX, OR RESPIRATION: DYSPNEA BEHAVIORAL: MUSCLE CONTRACTION OR SPASTICITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE	Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 34, Pg. 405, 1975.
mouse	LD50	intracrebral	95500ug/kg (95.5mg/kg)		Chemotherapy Vol. 17, Pg. 1111, 1969.
mouse	LD50	intraperitoneal	7600mg/kg (7600mg/kg)		Drugs in Japan Vol. 6, Pg. 187, 1982.
mouse	LD50	intravenous	4500mg/kg (4500mg/kg)		Chemotherapy Vol. 23, Pg. 572, 1975.
mouse	LD50	oral	> 12gm/kg (12000mg/kg)		Chemotherapy Vol. 23, Pg. 572, 1975.
mouse	LD50	subcutaneous	9gm/kg (9000mg/kg)		Drugs in Japan Vol. 6, Pg. 187, 1982.
rabbit	LD50	intravenous	> 4gm/kg (4000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
rabbit	LD50	subcutaneous	> 4gm/kg (4000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: OTHER: EYE	Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 11, Pg. 1589, 1969.
rat	LD50	intraperitoneal	10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 187, 1982.
rat	LD50	intravenous	6800mg/kg (6800mg/kg)		Drugs in Japan Vol. 6, Pg. 187, 1982.
rat	LD50	oral	> 10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 187, 1982.
rat	LD50	subcutaneous	> 10gm/kg (10000mg/kg)		Drugs in Japan Vol. 6, Pg. 187, 1982.

And if you need more detailed and technical information, you could refer to some leading suppliers in China. eg. Nanjing Aily Biotechnology Co.,Ltd. This company is one leading producer of Ferrocene carboxylic acid which is experienced in chemical manufacturing and custom synthesis.

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