Indacaterol, indacaterol copd, indacaterol maleate, indacaterol onbrez, onbrez indacaterol, qab 149, CAS No. 312753-06-3, fda indacaterol

HANGZHOU HOLYPHARM BIOTECH CO.,LTD

Country:China (Mainland)

Year Established: 2009Business type: Other

Integral:

1. What Is Indacaterol Maleate ?

Indacaterol (CAS No. 312753-06-3 ) is a novel, ultra-long-acting,β(2)-adrenoceptor agonist developed for Novartis for the once-daily treatment of asthma and chronic obstructive pulmonary disease(COPD),a lung disease that includes both emphysema and chronic bronchitis. With its Molecular Formula C₂₄H₂₈N₂O₃ and Molecular Weight 392.49, it is also called qab149;5-[(1R)-2-[(5,6-Diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-hydroxyquinolin-2(1H)-one.

2. The Properties of Indacaterol

The following are the predicted properties of Indacaterol by HANGZHOU HOLYPHARM BIOTECH CO.,LTD, a professional supplier of active pharmaceutical ingredients and intermediates.

water solubility: 7.98e-03 g/l
logP: 3.31
logP :3.26
logS: -4.7
pKa :14.06
hydrogen acceptor count:4
hydrogen donor count: 4
polar surface area :81.59
rotatable bond count: 6
refractivity :118.1
polarizability :44.96

3. What Is Indacaterol Maleate Used For ?

Indacaterol (Onbrez) was approved by the European Medicines Agency (EMA) under the trade name Onbrez on November 30, 2009, and by the United States Food and Drug Administration (FDA), under the trade name Arcapta Neohaler, on July 1, 2011.

People who have chronic obstructive pulmonary disease (COPD) may benefit from indacaterol maleate. As a type of beta agonist, this medicine works to prevent airway spasms by relaxing and opening up the airways in the lungs. Some off-label uses for indacaterol maleate include treating asthma or other breathing problems. This medicine is only approved for use in adults.

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