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Global Horizon Biotechnology Co., Ltd

Country:China (Mainland)

Year Established: 2005Business type: Trading Company

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 1. Pharmacology of 6-apb

 


6-APB is a triple monoamine reuptake inhibitor with Ki values of 117, 150 and 2698 for NET, DAT and SERT respectively as well as being a potent agonist for the 5-HT2B receptor (Ki 3.7nM).The subjective effects and structure–activity relationship suggest that it is also a releasing agent.

 The agonism for 5-HT2B makes it likely that 6-APB would be cardiotoxic with long term use, as seen in other 5-HT2B agonists such as fenfluramine and MDMA. 6-APB has also been claimed to act as an agonist of the 5-HT2C receptor and therefore be useful as an appetite suppressant.However while 6-APB is an agonist at all three 5-HT2 receptor subtypes, its potency at 5-HT2B is significantly higher, and it is actually both more potent and more selective over other serotonin receptors than the reference agonist BW723C86 which is commonly used for research into 5-HT2B receptors.

 

2. 6-apb dose

 

By having an idea of the proper dosage of 6-apb, you will be able to get better results. Taking extra dosage will lead to side effects and complications.

6-apb mainly falls under the classes of amphetamine and phenethylamine. However, the product does show certain differences. Even if someone is using the product in low proportions, it is important that he or she has an idea of the basic amount of dosage that has been recommended. Being a very strong drug, it can lead to various side effects. Lots of people use 6-apb for getting extra energy. Well, if taken well, it may improve the condition, but over the limit can be really dangerous to health.

 

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