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NANJING AILY BIOTECHNOLOGY CO.,LTD

Country:China (Mainland)

Year Established: Business type: Lab/Research institutions

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1. Rebamipide (mucosta)

With the CAS registry number 90098-04-7, rebamipide (mucosta) is one kind of white powder and it has the chemical Formula of C19H15ClN2O4 and molecular mass of 370.786 g/mol. When comes to its usage, mucosta (rebamipide) is one amino acid derivative of 2(1H)-quinolinone, and it also shows antiulcer activity in rats. This chemical could be applied in the treatment of Behçet's disease and pouchitis.

2. Two differenct configurations of Rebamipide (mucosta)

1). (-)-Configuration: Colorless acicular crystal; Obtained from dimethylformamide; Melting point: 305~306℃(decompose); [α]D20-116.7°(C=1.0,dimethylformamide).
2). (+)-Configuration: Colorless acicular crystal; Obtained from dimethylformamide; Melting point: 305~306℃(decompose); [α]D20+116.9°(C=1.0,dimethylformamide).

rebamipide chemical structrure

3. Rebamipide (mucosta) usage

Rebamipide could be used in the medicine market with the form of Mucosta tablet, such as Mucosta 100 mg, which is used in the treatment of gastric mucosal lesions (erosion, bleeding, redness & edema) in acute gastritis & acute exacerbation of chronic gastritis. And this mucosta dosage is as follows: 1 tab, 3 times a day; morning, evening & before bedtime. Just like other common drugs, mucosta 100 mg may also cause some adverse side effects. Rebamipide (mucosta) side effects are including mild reactions like nausea, diarrhea, vomiting, and there are also some serious side effects, such as menstrual disorders, increased BUN levels, edema, feeling of foreign body in the larynx.

Above usage and side effects information are not comprehensive, and you could refer to some leading manufacturers for some more detailed information, such as Nanjing Aily Biotechnology Co.,Ltd. This is one experienced producer of Rebamipide product, and it is engaged in the research of various kinds of chemicals.

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