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Hangzhou Chemfar Ltd.

Country:China (Mainland)

Year Established: 2002Business type: Other

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1.What is Diphenylamine?

DFA is the alias of Diphenylamine in chemistry, and Diphenylamine (CAS No. 122-39-4) is a plant growth regulator used post-harvest on apples to control storage scald. The application of dfa is often in fuel and explosive stabilizer. With the common name Diphenylamine (DPA) and the Chemical Name N-phenylbenzeneamine, it also has Trade and Other Names, such as DPA, Shield DPA, Big Dipper, Decoscald 282, and No Scald DPA 283. Diphenylamine has the molecular formula of C12H11N and a molecular weight of 169.22. The following are the other properties of diphenylamine:

Density: 1.16
Melting point : 52-54 ºC
Boiling point : 302 ºC
Flash point : 152 ºC
Water solubility : Slightly soluble. 0.03 g/100 mL

The Molecular Structure of Diphenylamine  :                                 The Molecular Structure of Diphenylamine



2. Structure of Diphenylamine


The application of dfa is great. Therefore, the researchers and the company of Hangzhou Chemfar Ltd., which has more than 20 years' experience focused on providing integrated development and manufacturing service to the pharmaceutical and fine chemical industry, are in the study of the role of diphenylamine structure in liver injuries induced by these NSAIDs. It was pointed that many nonsteroidal anti-inflammatory drugs (NSAIDs) with diphenylamine structure induce severe hepatotoxicities. Now the researchers, but after many experiments, the hepatotoxicities caused by diclofenac and tolfenamic acid may be attributed to the mitochondrial dysfunction induced by these drugs instead of the diphenylamine structure.

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