Country:China (Mainland)
Year Established: 2009Business type: Other
Integral:
1. The brief introduction of Onglyza
Onglyza(Saxagliptin) is a prescription medicine licensed for the treatment of type 2 diabetes. It is the trade name of saxagliptin. Onglyza is the second approved medication belonging to dipeptidyl peptidase-4 (DPP-4) inhibitors. And the FDA approved Saxagliptin with brand name Onglyza on July 31, 2009.
Onglyza tablets contain the active ingredient saxagliptin which is a type of medicine. It also contains lactose, so it should not be taken by people with rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption.
2. The usage of Onglyza
Onglyza is made by Bristol-Myers Squibb (BMS) and is marketed by BMS and AstraZeneca Pharmaceuticals LP. Because it contains saxagliptin, it works by increasing the amount of two incretin hormones found in the body, called glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). GLP-1 and GIP have two main actions that help to control blood glucose. Then it help control blood sugar (glucose) levels.
3. The side effect of Onglyza
Every medicine has its side effects, hence serious side effects can happen to people taking ONGLYZA, some Onglyza side effects are as follows:
Upper respiratory tract infection, urinary tract infection, gastroenteritis, sinusitis, headache, nausea and vomiting, dizziness, fatigue, rash are the common symptom.
When used with a sulphonylurea such as glibenclamide, you may be in low blood sugar levels.
When used with metformin, you may feel muscle pain.
When used with metformin, you may indigest, even turn into inflammation of the stomach (gastritis).
When used with a glitazone, swelling of the legs and ankles due to excess fluid retention will appear.
1,1,3,3-Tetramethoxypropane(CAS:102-52-3), is used as medicine and dye intermediates. There are many 1,1,3,3-Tetramethoxypropane manufactures in China.
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