1,2-Dichloroethane supplier

Name
1,2-Dichloroethane
EINECS 203-458-1
CAS No. 107-06-2
Article Data318
CAS DataBase
Density 1.173 g/cm³
Solubility 8.7 g/L (20℃)
Melting Point -35 °C
Formula C₂H₄Cl₂
Boiling Point 83.5 °C at 760 mmHg
Molecular Weight 98.9598
Flash Point 15.6 °C
Transport Information UN 1184 3/PG 2
Appearance clear liquid
Safety 53-45-24-16-7
Risk Codes 45-11-22-36/37/38-23/25
Molecular Structure
Hazard Symbols F,T
Synonyms 1,2-Bichloroethane;1,2-Dichlorethane;1,2-Ethylene dichloride;Brocide;DCE;Dichlor-Mulsion;Dutch liquid;EDC;EDC (halocarbon);Ethylene chloride;Ethylene dichloride;Glycol dichloride;HCC 150;sym-Dichloroethane;a,b-Dichloroethane;1,2-Dichloroethane;
PSA 0.00000
LogP 1.46400

Synthetic route

: 75-21-8
oxirane

: 5003-97-4
trichlorodistyrylphosphorane

A: 139888-58-7
Bis-((E)-styryl)-phosphinic acid 2-chloro-ethyl ester

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With titanium tetrachloride In benzene at 40℃;	A 91% B n/a

...Expand

: 75-21-8
oxirane

: 4895-49-2, 40851-17-0
Styryl-phosphortetrachlorid

A: 39229-97-5
bis(2-chloroethyl) styrylphosphonate

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With titanium tetrachloride In benzene at 40℃;	A 90% B n/a

...Expand

: 75-01-4
chloroethylene

A: 75-34-3
1,1-dichloroethane

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With chlorotrifluoromethane; hydrogen iodide Product distribution; Mechanism; Irradiation; var. pressure; labeling (38)Cl;	A 0.76% B 78%

: 74-85-1
ethene

: 7182-86-7
tetrabutylammonium p-toluenesulfonate

A: 80-41-1
2-chloroethyl tosylate

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With chlorine In dichloromethane at 20℃; for 0.25h; Product distribution; Mechanism;	A 43% B 57 % Spectr.
With chlorine In dichloromethane at 20℃; for 0.25h;	A 43% B 57 % Spectr.
With chlorine In dichloromethane Ambient temperature;

...Expand

: 74-85-1
ethene

A: 80-41-1
2-chloroethyl tosylate

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With tetrabutylammonium p-toluenesulfonate; chlorine In dichloromethane at 20℃; for 0.25h;	A 43% B 57 % Spectr.

: 75-09-2
dichloromethane

: 62-53-3
aniline

A: 100-62-9
N-methylenebenzenamine

B: 74-87-3
methylene chloride

C: 107-06-2
1,2-dichloro-ethane

D: 1227476-15-4
Azobenzene

E: 101-54-2
N-phenylphenylene-1,4-diamine

F: 534-85-0
N-phenyl-1,2-benzenediamine

G chloromethane: chloromethane

Conditions

Conditions	Yield
at 15℃; for 24h; Product distribution; Mechanism; Irradiation;	A n/a B n/a C n/a D 18.6% E 15.6% F 25.8% G n/a

...Expand

: 18407-40-4
chloromethyl-methyl-diphenyl-silane

A: 75-79-6
Methyltrichlorosilane

B: 92-52-4
biphenyl

C: 144-79-6
chloromethyldiphenylsilane

D: 98-13-5
Phenyltrichlorosilane

E: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
iron(III) chloride at 70℃; for 0.5h; Product distribution; other conditions: other catalyst, other temperature;	A 8% B 10% C 17% D 14% E 22%

...Expand

: 177-10-6
1,3-dioxolane-2-spirocyclohexane

A: 22354-42-3
6-(1-cyclohexenyl)caproic acid β-chloroethyl ester

B: 107-21-1
ethylene glycol

C: 107-06-2
1,2-dichloro-ethane

D: 107-07-3
2-chloro-ethanol

Conditions

Conditions	Yield
With hydrogenchloride at 150℃; for 2h;	A 15% B n/a C n/a D n/a

...Expand

: 176-32-9
1,4-dioxaspiro[4.4]nonane

A: 23182-13-0
5-(1-cyclopentenyl)valeric acid β-chloroethyl ester

B: 107-21-1
ethylene glycol

C: 107-06-2
1,2-dichloro-ethane

D: 107-07-3
2-chloro-ethanol

Conditions

Conditions	Yield
With hydrogenchloride at 150℃; for 2h;	A 14% B n/a C n/a D n/a

...Expand

: 75-21-8
oxirane

: 5813-48-9
Methanesulfenyl chloride

A: 624-92-0
Dimethyldisulphide

B: 118725-60-3
methanesulfinic acid-(2-chloro-ethyl ester)

C: 107-06-2
1,2-dichloro-ethane

...Expand

: 75-21-8
oxirane

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With disulfur dichloride

: 74-87-3
methylene chloride

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
Einw. dunkler elektrischer Entladungen;

: 74-87-3
methylene chloride

A: 96-18-4
1,2,3-trichloropropane

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
bei der Einwirkung dunkler elektrischer Entladungen;

: 13891-58-2
chloroethyl chlorosulfate

: 62516-55-6
sulfurous acid bis-(2-chloro-ethyl ester)

A: 5411-48-3
sulfuric acid bis-(2-chloroethyl) ester

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
at 130 - 175℃;
at 130 - 175℃;
With zinc(II) chloride at 130 - 175℃;

...Expand

: 62516-55-6
sulfurous acid bis-(2-chloro-ethyl ester)

A: 41239-98-9
2-chloroethyl chlorosulphite

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With tetrachloromethane; phosphorus pentachloride

: 5411-48-3
sulfuric acid bis-(2-chloroethyl) ester

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With hydrogenchloride; alkali chloride

: 115-96-8
Tris(2-chloroethyl) phosphate

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
erfolgt Zersetzung;

: 64-17-5
ethanol

: 98020-30-5
dichloro-(2-chloro-ethoxy)-acetyl chloride

A: 75-00-3
chloroethane

B: 107-06-2
1,2-dichloro-ethane

C: 95-92-1
oxalic acid diethyl ester

Conditions

Conditions	Yield
zuletzt in der Siedehitze; reagiert analog mit Methanol und Isopropylalkohol;

...Expand

: 64-17-5
ethanol

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With hydrogenchloride; aluminum oxide; air; water; sodium chloride; copper dichloride at 225℃; unter Druck;
With hydrogenchloride; aluminum oxide; air; water; sodium chloride; copper dichloride at 280 - 290℃;

: 74-85-1
ethene

: 3135-74-8
chlorourea

A: 107-06-2
1,2-dichloro-ethane

B: 107-07-3
2-chloro-ethanol

Conditions

Conditions	Yield
With sulfuric acid; copper dichloride at 0℃;

...Expand

: 74-85-1
ethene

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With chlorine
With chlorine at -78℃;
With chlorine; ethylene dibromide at 40 - 100℃; ueber poroeses Material;

: 74-85-1
ethene

A: 41239-98-9
2-chloroethyl chlorosulphite

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With sulfuryl dichloride at 20℃;
With disulfur dichloride; sulfuryl dichloride; sulfur dichloride at 20℃;

: 74-85-1
ethene

A: 624-73-7
1,2-Diiodoethane

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With water; Iodine monochloride

: 74-85-1
ethene

A: 107-06-2
1,2-dichloro-ethane

B: 111-44-4
3-oxa-1,5-dichloropentane

Conditions

Conditions	Yield
With chlorine; 2-chloro-ethanol
With oxirane; chlorine
With oxirane; chlorine; 2-chloro-ethanol

: 75-00-3
chloroethane

: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
With chlorine
With chlorine im Licht;
With antimonypentachloride at 100℃;
With water Chlorierung;

: 75-00-3
chloroethane

A: 75-34-3
1,1-dichloroethane

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
at 0℃; Einfluss des Loesungsmittels auf die Photochlorierung;
With chlorine In chlorobenzene Mechanism; Kinetics; other solvent; object of study: solvents effects vs. the reaction selectivity;
With chlorine In gas at 8 - 94℃; Kinetics; Thermodynamic data; Mechanism; ΔE(excit);

: 505-60-2
bis (2-chloroethyl) sulphide

A: 505-29-3
1,4-Dithiane

B: 107-06-2
1,2-dichloro-ethane

Conditions

Conditions	Yield
at 180℃;
at 180℃; Gleichgewicht;

: 7300-22-3
4,4′-methylenedibenzenethiol

: 107-06-2
1,2-dichloro-ethane

: 152419-81-3
C17H18Cl2S2

Conditions

Conditions	Yield
With potassium hydroxide; tetrabutylammomium bromide for 0.333333h; Ambient temperature;	100%

: 612501-52-7
4-((3-chloro-2-fluorophenyl)amino)-7-methoxyquinazolin-6-ol

: 107-06-2
1,2-dichloro-ethane

: 848440-10-8
C17H14Cl2FN3O2

Conditions

Conditions	Yield
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 60℃; for 48h;	100%

: 296764-06-2
trans-4-(2,4-Bis{[tert-butyl(dimethyl)silyl]oxy}phenyl)cyclohexylamine

: 124-63-0
methanesulfonyl chloride

: 107-06-2
1,2-dichloro-ethane

: 296764-23-3
trans-N-[4-(2,4-Bis{[tert-butyl(dimethyl)silyl]oxy}phenyl)cyclohexyl] Methane Sulfonamide

Conditions

Conditions	Yield
With triethylamine In dichloromethane; water	100%

...Expand

: 100-02-7
4-nitro-phenol

: 79-37-8
oxalyl dichloride

: 107-06-2
1,2-dichloro-ethane

: 128015-91-8
4-nitrophenyl 4-acetylbenzoate

Conditions

Conditions	Yield
With sodium hydrogencarbonate In dichloromethane; chloroform; 4-acetyl-benzoic acid	100%

...Expand

: 5,5,20,20,35,35-hexachloro-4,4,6,6,19,19,21,21,34,34,36,36-dodecaphenyl-4,6,19,21,34,36-hexaphospha-5,20,35-triplatina[9(3)](1,3,5)cyclophane

: 107-06-2
1,2-dichloro-ethane

: 5,5,20,20,35,35-hexachloro-4,4,6,6,19,19,21,21,34,34,36,36-dodecaphenyl-4,6,19,21,34,36-hexaphospha-5,20,35-triplatina[9(3)](1,3,5)cyclophane*7(1,2-dichloroethane)

Conditions

Conditions	Yield
In 1,2-dichloro-ethane Ar atmosphere; removement of excess solvent (vacuum); elem. anal.;	100%

: 616-47-7
1-methyl-1H-imidazole

: 107-06-2
1,2-dichloro-ethane

: 1,1'-dimethyl-3,3'-(1,2-dimethylene)bisimidazolium dichloride

Conditions

Conditions	Yield
at 110℃; for 17h; Darkness;	100%
In chloroform at 60℃; under 14251400 Torr; for 24h; Pressure; Menshutkin Reaction; High pressure;	95%
at 110℃; for 6h; neat (no solvent);	91%

: 107-06-2
1,2-dichloro-ethane

: 86-93-1
1-Phenyl-1H-tetrazole-5-thiol

: 1153358-38-3
5-((2-chloroethyl)thio)-1-phenyl-1H-tetrazole

Conditions

Conditions	Yield
With caesium carbonate In acetonitrile at 60℃; for 72h;	100%
With potassium carbonate for 48h; Reflux;

: 1449661-53-3
(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-amino-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)octadecahydro-1H-cyclopenta[a]chrysen-9(5bH)-one hydrochloride

: 107-06-2
1,2-dichloro-ethane

: 1449662-09-2
(1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-3a-(aziridin-1-yl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)octadecahydro-1H-cyclopenta[a]chrysen-9(5bH)-one

Conditions

Conditions	Yield
With potassium phosphate In acetonitrile at 130℃; for 36h; Concentration; Time; Inert atmosphere; Sealed tube;	100%

: 1450665-97-0
4'-(4-pyridin-4-ylethynyl-phenyl)[2,2';6',2'']terpyridine

: 1450665-95-8
2,9-bis(2,6-dimethoxyphenyl)-3-((2,3,5,6-tetramethyl-4-(pyridin-4-ylethynyl)phenyl)ethynyl)-1,10-phenanthroline

: 54010-75-2
zinc trifluoromethanesulfonate

: 107-06-2
1,2-dichloro-ethane

: C75H57N7O4Zn(2+)*2CF3O3S(1-)*2.25C2H4Cl2

Conditions

Conditions	Yield
In acetonitrile for 2h; Reflux;	100%

...Expand

: 7677-24-9
trimethylsilyl cyanide

: 5-methyl-3,3-diphenyl-3,4-dihydro-2H-pyrrole

: 107-06-2
1,2-dichloro-ethane

: 5-methyl-3,3-diphenyl-3,4-dihydro-2H-pyrrole

: 1-(2-chloroethyl)-2-methyl-4,4-diphenylpyrrolidine-2-carbonitrile

Conditions

Conditions	Yield
With copper(I) bromide at 90℃; for 0.5h; Microwave irradiation;	100%

...Expand

: 15953-73-8
4-Chloro-3,5-dimethylpyrazole

: 107-06-2
1,2-dichloro-ethane

: 4-chloro-1-(2-chloroethyl)-3,5-dimethyl-1H-pyrazole

Conditions

Conditions	Yield
With tetrabutyl-ammonium chloride; sodium hydroxide In water	100%

: 3398-16-1
4-Bromo-3,5-dimethylpyrazole

: 107-06-2
1,2-dichloro-ethane

: C7H10BrClN2

Conditions

Conditions	Yield
With tetrabutyl-ammonium chloride; sodium hydroxide In water	100%

: 107-06-2
1,2-dichloro-ethane

A: 7647-01-0
hydrogenchloride

B: 75-01-4
chloroethylene

Conditions

Conditions	Yield
at 450 - 550℃; under 10501.1 - 26252.6 Torr; for 0.00416667 - 0.00833333h;	A n/a B 99.52%
at 362 - 485℃; eine nahezu homogene Reaktion erster Ordnung, die wahrscheinlich von Chloratomen und 1.2-Dichlor-aethyl-Radikalen unterhalten wird.Thermolysis;
at 600℃; Conversion of starting material;
at 615℃; Rate constant;
at 650℃; Rate constant;

: 107-06-2
1,2-dichloro-ethane

: 75-01-4
chloroethylene

Conditions

Conditions	Yield
With triethylbenzylammonium ethanolate at -20 - 20℃;	99%
	75%
With polyacrylonitrile-based active carbon fiber at 350℃; under 760 Torr; for 2h; other catalyst, var. reaction time;	57%

: 58-55-9
theophylline

: 107-06-2
1,2-dichloro-ethane

: 5878-61-5
7-(2-chloroethyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione

Conditions

Conditions	Yield
With sodium hydroxide; Aliquat 336 for 4h; Heating;	99%
With sodium hydroxide In water; isopropyl alcohol at 78 - 80℃; for 76.5h; Heating;	90%
In water; dimethyl sulfoxide

: 6954-27-4
(1,1'-biphenyl)-4,4'-dithiol

: 107-06-2
1,2-dichloro-ethane

: 152419-83-5
4,4'-Bis-(2-chloro-ethylsulfanyl)-biphenyl

Conditions

Conditions	Yield
With potassium hydroxide; tetrabutylammomium bromide for 0.333333h; Ambient temperature;	99%

phosgene trimer: phosgene trimer

: 1877-72-1
3-Cyanobenzoic acid

: 107-06-2
1,2-dichloro-ethane

: 1711-11-1
3-cyanobenzoyl chloride

Conditions

Conditions	Yield
With pyridine	99%

...Expand

: 496-16-2
2,3-Dihydrobenzofuran

: 107-06-2
1,2-dichloro-ethane

: 115010-11-2
2,3-dihydrobenzofuran-5-sulfonyl chloride

Conditions

Conditions	Yield
With thionyl chloride In water	99%

: 274-09-9
Methylenedioxybenzene

: 107-06-2
1,2-dichloro-ethane

: 63758-12-3
6-chlorosulfonyl-1,4-benzodioxane

Conditions

Conditions	Yield
With thionyl chloride In water	99%

trans-1,2-cyclohexanbicarboxylic anhydride: trans-1,2-cyclohexanbicarboxylic anhydride

: 3183-20-8
ethyl N-ethyl-glycinate

: 107-06-2
1,2-dichloro-ethane

: Trans-2[[N-[2-(hydroxyamino)-2-oxoethyl]-N-ethylamino]carbonyl]--cyclohexanecarboxylic acid

Conditions

Conditions	Yield
With hydrogenchloride; sodium hydroxide; sodium chloride; hydroxylamine hydrochloride In methanol; dichloromethane; chloroform; water	99%
With hydrogenchloride; sodium hydroxide; sodium chloride; hydroxylamine hydrochloride In methanol; dichloromethane; chloroform; water	99%

...Expand

: 107-06-2
1,2-dichloro-ethane

: 20667-12-3
silver(l) oxide

: 330455-95-3
3-(N,N-diethylcarbamoylmethyl)-1-mesitylimidazolium bromide

: [1-(N,N-diethylcarbamoylmethyl)-3-mesitylimidazol-2-ylidene]silver chloride bromide

Conditions

Conditions	Yield
In 1,2-dichloro-ethane heating of excess of Ag2O and C18H26BrN3O in 1,2-dichloroethane at 90°C for 4 h in the presence of molecular sieves; filtration, removal of solvent in vacuo, washing with ether with hygroscopic solid; elem. anal.;	99%

...Expand

: 148352-98-1
Yb(2,6-di-tert-butylphenolate)2(THF)3

: 107-06-2
1,2-dichloro-ethane

: 359860-06-3
chlorobis(2,6-di-tert-butylphenolato)bis(tetrahydrofuran)ytterbium(III)

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: C2H4, THF; under Ar or N2, 0.5 equiv. of halogen-compd. was added to Yb-compd. soln. in THF, stirring for 24 h at room temp.; volatiles were removed in vac., solid was dried in vac. at room temp., elem. anal.;	99%

: 166943-01-7, 148352-99-2
tris(tetrahydrofuran)bis(2,4,6-tri-t-butylphenolato)ytterbium(II)

: 107-06-2
1,2-dichloro-ethane

: 359860-13-2
chlorobis(2,4,6-tri-tert-butylphenolato)bis(tetrahydrofuran)ytterbium(III)

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: C2H4, THF; under Ar or N2, 0.5 equiv. of halogen-compd. was added to Yb-compd. soln. in THF, stirring for 24 h at room temp.; volatiles were removed in vac., solid was dried in vac. at room temp., elem. anal.;	99%

: 166943-03-9, 158706-11-7, 124206-20-8
Yb(2,6-di-tert-butyl-4-methylphenolate)2(THF)3

: 107-06-2
1,2-dichloro-ethane

: 359860-09-6
chlorobis(2,6-di-tert-butyl-4-methylphenolato)bis(tetrahydrofuran)ytterbium(III)

Conditions

Conditions	Yield
In tetrahydrofuran byproducts: C2H4, THF; under Ar or N2, 0.5 equiv. of halogen-compd. was added to Yb-compd. soln. in THF, stirring for 24 h at room temp.; volatiles were removed in vac., solid was dried in vac. at room temp., elem. anal.;	99%

: 727737-96-4
chloro(trimethylamine-isocyanoborane)gold(I)

: 107-06-2
1,2-dichloro-ethane

: 7681-11-0
potassium iodide

: bis(trimethylamine-isocyanoborane)gold(I) diiodogold(I) 1,2-dichloromethane adduct (3/4)

Conditions

Conditions	Yield
In dichloromethane; water (Ar); a soln. of Au complex in CH2Cl2 poured into an aq. soln. of KI, stirred for 18 h; phases sepd., the aq. phase extd. (CH2Cl2), the org. exts. combined, recrystd. (1,2-dichloroethane and pentane); elem. anal.;	99%

...Expand

: [(Me5C5)4Ir4(μ-trans-1,2-bis(4-pyridyl)ethylene)2(μ-η2-η2-C2O4)2][OTF]4*4H2O

: 107-06-2
1,2-dichloro-ethane

: [((CH3)5C5)4Ir4(C2O4)2(C5H4NCHCHC5H4N)2](4+)*4CF3SO3(1-)*C2H4Cl2=[((CH3)5C5)4Ir4(C2O4)2((C5H4NCH)2)2][CF3SO3]4*C2H4Cl2

Conditions

Conditions	Yield
In neat (no solvent, solid phase) Irradiation (UV/VIS); treated for 25 h; crystd. (CH2Cl2/Et2O), elem. anal.;	99%

: 2Li(1+)*B12Cl12(2-) = Li2B12Cl12

: 76-83-5
trityl chloride

: 107-06-2
1,2-dichloro-ethane

: [CPh3]2[B12Cl12]*2(1,2-dichloroethane)

Conditions

Conditions	Yield
In sulfur dioxide under Ar atm. SO2 was condensed onto mixt. Ph3CCl and Li2(B12Cl12), warmed and stirred at room temp. for 1 h; volatiles were removed in vacuo, residue was extd. with 1,2-C2H4Cl2;	99%

...Expand

: 1177404-20-4
N,N'-dimethyl-N,N'-hexamethylenebis(5-tert-butyl-2-hydroxy-3-hydroxyiminomethyl)benzylamine

: 6046-93-1
copper(II) acetate monohydrate

: 107-06-2
1,2-dichloro-ethane

: bis(N,N'-dimethyl-N,N'-hexamethylenedi(3-hydroxyiminomethyl-2-hydroxy-5-tert-butylbenzylamino))dicopper(II) - 1,2-dichloroethane (1/2)

Conditions

Conditions	Yield
In ethanol; 1,2-dichloro-ethane soln. of Cu salt and ligand (1:1) in 1,2-dichloroethane and EtOH (1:4 v/v) stirred at 40°C for 24 h; evapd.(vac.), took with C2H4Cl2, filtered, crystd. for a few d, elem. anal.;	99%

...Expand

: 107-06-2
1,2-dichloro-ethane

: 65-85-0
benzoic acid

: 939-55-9
2-chloroethyl benzoate

Conditions

Conditions	Yield
With potassium carbonate In dimethyl sulfoxide at 35℃; for 4h;	99%

: 7677-24-9
trimethylsilyl cyanide

: 1236352-67-2
2,2-diphenyl-4-pentyn-1-amine

: 107-06-2
1,2-dichloro-ethane

: 1-(2-chloroethyl)-2-methyl-4,4-diphenylpyrrolidine-2-carbonitrile

Conditions

Conditions	Yield
With water; copper(I) bromide In acetonitrile at 90℃; for 0.666667h; Inert atmosphere; Microwave irradiation;	99%

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1,2-Dichloroethane History

In 1794, a group of four Dutch friends under the name of Gezelschap der Hollandsche Scheikundigen consisted of physician Jan Rudolph Deiman, merchant Adriaan Paets van Troostwijk, chemist Anthoni Lauwerenburg and botanist Nicolaas Bondt. They were the first to produce 1,2-dichloroethane(107-06-2) from olefiant gas and chlorine gas. Although the Gezelschap in practice didn't do much in-depth scientific research, they and their publications were highly regarded. Part of that acknowledgement is that 1,2-dichloroethane(107-06-2) has been called Dutch oil in old chemistry.

1,2-Dichloroethane Specification

The 1,2-Dichloroethane is an organic compound with the formula C₂H₄Cl₂. The IUPAC name of this chemical is 1,2-dichloroethane. With the CAS registry number 107-06-2, it is also named as 1,2-Ethylidene dichloride. The product's categories are Refrigerants; Organics; alpha,omega-Bifunctional Alkanes; alpha,omega-Dichloroalkanes; Analytical Chemistry; Monofunctional & alpha,omega-Bifunctional Alkanes; Solvents for HPLC & Spectrophotometry; Solvents for Spectrophotometry; Alpha Sort; D; DAlphabetic; DIA - DIC; Volatiles/Semivolatiles. Besides, it is clear liquid, which should be stored in a cool and well-ventilated place.

Physical properties about 1,2-Dichloroethane are:
(1)ACD/LogP: 1.41; (2)ACD/LogD (pH 5.5): 1.41; (3)ACD/LogD (pH 7.4): 1.41; (4)ACD/BCF (pH 5.5): 6.99; (5)ACD/BCF (pH 7.4): 6.99; (6)ACD/KOC (pH 5.5): 139.95; (7)ACD/KOC (pH 7.4): 139.95; (8)#Freely Rotating Bonds: 1; (9)Index of Refraction: 1.412; (10)Molar Refractivity: 21.01 cm³; (11)Molar Volume: 84.3 cm³; (12)Polarizability: 8.33×10^-24cm³; (13)Surface Tension: 25 dyne/cm; (14)Density: 1.173 g/cm³; (15)Flash Point: 15.6 °C; (16)Enthalpy of Vaporization: 31.98 kJ/mol; (17)Boiling Point: 83.5 °C at 760 mmHg; (18)Vapour Pressure: 83.9 mmHg at 25°C.

Preparation of 1,2-Dichloroethane:
Production is primarily achieved through the iron(III) chloride-catalysed reaction of ethene (ethylene) and chlorine.
H₂C=CH₂ + Cl₂ → ClCH₂-CH₂Cl
1,2-dichloroethane is also generated by the copper(II) chloride-catalysed "oxychlorination" of ethylene:
H₂C=CH₂ + 2 HCl + ½ O₂ → ClCH₂-CH₂Cl + H₂O
In principle, it can be prepared by the chlorination of ethane and, less directly, from ethanol.

Uses of 1,2-Dichloroethane:
with approximately 80% of the world's consumption of 1,2-dichloroethane, the major use of 1,2-dichloroethane is in the production of vinyl chloride monomer (VCM, chloroethene) with hydrogen chloride as a byproduct. VCM is the precursor to polyvinyl chloride.
Cl-CH₂-CH₂-Cl → H₂C=CH-Cl + HCl
The hydrogen chloride can be re-used in the production of more 1,2-dichloroethane via the oxychlorination route described above.

When you are using 1,2-Dichloroethane, please be cautious about it as the following:
It is highly flammable and harmful if swallowed. It is toxic by inhalation and if swallowed. Please keep container tightly closed and keep away from sources of ignition - No smoking. Besides, this chemical is irritating to eyes, respiratory system and skin and may cause cancer. When you are using it, do not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer). In case of accident or if you feel unwell seek medical advice immediately (show the label where possible).

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C(CCl)Cl
(2)InChI: InChI=1S/C2H4Cl2/c3-1-2-4/h1-2H2
(3)InChIKey: WSLDOOZREJYCGB-UHFFFAOYSA-N

The toxicity data of 1,2-Dichloroethane is as follows:

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
cat	LC	inhalation	> 3000ppm/7H (3000ppm)		Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.
dog	LD50	oral	5700mg/kg (5700mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: ATAXIA	FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970.
dog	LDLo	intravenous	175mg/kg (175mg/kg)		Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
guinea pig	LCLo	inhalation	1500ppm/7H (1500ppm)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE KIDNEY, URETER, AND BLADDER: "CHANGES IN TUBULES (INCLUDING ACUTE RENAL FAILURE, ACUTE TUBULAR NECROSIS)" BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)	Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.
guinea pig	LDLo	intraperitoneal	600mg/kg (600mg/kg)		American Industrial Hygiene Association Journal. Vol. 35, Pg. 21, 1974.
human	LDLo	oral	286mg/kg (286mg/kg)	GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: FATTY LIVER DEGERATION	Casopis Lekaru Ceskych. Journal of Czech Physicians. Vol. 86, Pg. 203, 1947.
human	TDLo	oral	428mg/kg (428mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: COUGH GASTROINTESTINAL: NAUSEA OR VOMITING	Sovetskaia Meditsina. Vol. 22(10), Pg. 132, 1958.
mammal (species unspecified)	LC	inhalation	> 3000ppm/7H (3000ppm)		Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.
man	LDLo	oral	714mg/kg (714mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) CARDIAC: CHANGE IN RATE LUNGS, THORAX, OR RESPIRATION: CYANOSIS	Klinische Wochenscrift. Vol. 48, Pg. 822, 1970.
man	TCLo	inhalation	4000ppm/1H (4000ppm)	PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: COMA GASTROINTESTINAL: NAUSEA OR VOMITING	Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 500, 1966.
man	TDLo	oral	892mg/kg (892mg/kg)	GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" GASTROINTESTINAL: NAUSEA OR VOMITING LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED"	Wiadomosci Lekarskie. Medical News. Vol. 28, Pg. 983, 1975.
monkey	LC50	inhalation	3000ppm/7H (3000ppm)		"Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986Vol. -, Pg. 93, 1986.
mouse	LCLo	inhalation	5gm/m³/2H (5000mg/m³)		Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 141, Pg. 19, 1929.
mouse	LD50	intraperitoneal	470mg/kg (470mg/kg)		Arzneimittel-Forschung. Drug Research. Vol. 11, Pg. 902, 1961.
mouse	LD50	oral	413mg/kg (413mg/kg)	LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES LIVER: OTHER CHANGES	EHP, Environmental Health Perspectives. Vol. 43, Pg. 41, 1982.
mouse	LDLo	subcutaneous	380mg/kg (380mg/kg)		Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.
pig	LCLo	inhalation	3000ppm/7H (3000ppm)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.
rabbit	LCLo	inhalation	3000ppm/7H (3000ppm)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES	Journal of Pharmacology and Experimental Therapeutics. Vol. 84, Pg. 53, 1945.
rabbit	LD50	oral	860mg/kg (860mg/kg)		Guide to the Chemicals Used in Crop Protection. Vol. 6, Pg. 264, 1973.
rabbit	LD50	skin	2800mg/kg (2800mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA BEHAVIORAL: GENERAL ANESTHETIC	FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970.
rabbit	LDLo	subcutaneous	1200mg/kg (1200mg/kg)		Quarterly Journal of Pharmacy & Pharmacology. Vol. 7, Pg. 205, 1934.
rat	LC50	inhalation	1000ppm/7H (1000ppm)	BEHAVIORAL: COMA LUNGS, THORAX, OR RESPIRATION: CYANOSIS	AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 482, 1951.
rat	LD50	intraperitoneal	807mg/kg (807mg/kg)		Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 26(4), Pg. 26, 1982.
rat	LD50	oral	670mg/kg (670mg/kg)		Farm Chemicals Handbook. Vol. -, Pg. C130, 1991.
rat	LD50	subcutaneous	1gm/kg (1000mg/kg)	SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: GENERAL ANESTHETIC BEHAVIORAL: ATAXIA	FAO Nutrition Meetings Report Series. Vol. 48A, Pg. 91, 1970.
rat	LDLo	intratracheal	120mg/kg (120mg/kg)		National Technical Information Service. Vol. OTS0520615,

Product Name

1,2-Dichloroethane

Synthetic route

1,2-Dichloroethane History

1,2-Dichloroethane Specification

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