Country:China (Mainland)
Year Established: 2009Business type: Other
Integral:
1. What is Ibutamoren?
Ibutamoren/MK677 (CAS NO.159634-47-6) is 2-Amino-N-[(1R)-2-[1,2-dihydro-1-(methylsulfonyl)spiro[3H-indole-3,4'-piperidin]-1'-yl]-2-oxo-1-[(phenylmethoxy)methyl]ethyl]-2-methylpropanamide methanesulfonate. MK677 CAS159634-47-6 formula is C27H36N4O5S.CH4O3S. Ibutamoren molecular weight is 624.77. It has several synonyms such as L 163191, MK-0677 or MK-677. When you want to buy ibutamoren, please come to HANGZHOU HOLYPHARM BIOTECH CO.,LTD.
2. Other properties of Ibutamoren
Ibutamoren Structure:
Others:
(1)ACD/LogP: 2.842 ; (2)# of Rule of 5 Violations: 1 ; (3)ACD/LogD (pH 5.5): 0.76 ; (4)ACD/LogD (pH 7.4): 2.42 ; (5)ACD/BCF (pH 5.5): 1.00 ; (6)ACD/BCF (pH 7.4): 31.90 ; (7)ACD/KOC (pH 5.5): 6.92 ; (8)ACD/KOC (pH 7.4): 313.99 ; (9)#H bond acceptors: 9 ; (10)#H bond donors: 3 ; (11)#Freely Rotating Bonds: 9 ; (12)Polar Surface Area: 130.42 Å2 ; (13)Index of Refraction: 1.631 ; (14)Molar Refractivity: 142.66 cm3 ; (15)Molar Volume: 400.077 cm3 ; (16)Polarizability: 56.555 10-24cm3 ; (17)Surface Tension: 63.484001159668 dyne/cm ; (18)Density: 1.321 g/cm3.
3. Information about this agent
Ibutamoren (MK-677, L-163,191) is a drug which acts as a potent, orally active growth hormone secretagogue, mimicking the GH stimulating action of the endogenous hormone ghrelin. Some studies show it is currently under development as a potential treatment for reduced levels of these hormones, such as in growth hormone deficient children or elderly adults and human studies have shown it to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly.
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