Bortezomib, marketed as Velcade by Millennium Pharmaceuticals, is the first therapeutic proteasome inhibitor to be tested in humans. It is approved in the U.S. for treating relapsed multiple myeloma and mantle cell lymphoma. In multiple myeloma, complete clinical responses have been obtained in patients with otherwise refractory or rapidly advancing disease.
1. The basic information of Bortezomib (velcade
)
CAS NO : 179324-69-7
Bortezomib Molecular Weight: 384.24
Molecular Formula: C19H25BN4O4
Boiling Point: 130.5°C (266.9°F)
Melting Point: -23°C (-9.4°F)
Bortezomib structure:
2. The process of Bortezomib synthesis
Nanjing Aily Biotechnology Co.,Ltd., as a specialized company in chemical manufacture and custom synthesis, has 3 OEM factories, 2 R&D labs at present. The following is the process of Bortezomib synthesis given by them.
.jpg)
3. How velcade (bortezomib) Works
Velcade is an important option for treating patients with multiple myeloma and patients with relapsed mantle cell lymphoma (MCL) because it gives you another way to fight your disease. Velcade is a type of medicine called a proteasome (pro-tee-uh-zohm) inhibitor. It is the only proteasome inhibitor the FDA has approved.
Velcade is a proteasome inhibitor that temporarily blocks, or inhibits, proteasomes from breaking down proteins. This causes a buildup of proteins in the cell. When there are too many proteins in the cells, the cells stop growing and die.
<span style="width: 640px; color: #000000; font-size: 12px; word-break: break-all"> </span></p>
<div><font size="3" face="Arial">We are a specialized company in chemical manufacture and custom synthesis. Our factory was established in 1997, and set up <span class="scayt-misspell" data-scaytid="5" data-scayt_word="Nanjing">Nanjing</span> <span class="scayt-misspell" data-scaytid="7" data-scayt_word="Aily">Aily</span> Biotechnology Co.,Ltd in 2008. Now we have 3 OEM factories, 2 R&D labs. <span class="scayt-misspell" data-scaytid="9" data-scayt_word="Aily">Aily</span> is striving to improve <span class="scayt-misspell" data-scaytid="13" data-scayt_word="reseach">reseach</span> and development, meet social and customers needs with a unifying strategic <span class="scayt-misspell" data-scaytid="3" data-scayt_word="idea.Pls">idea.Pls</span> find our factory details as <span class="scayt-misspell" data-scaytid="15" data-scayt_word="fallowings">fallowings</span>.</font></div>
<div align="left"><font face="Arial"><font size="3">Our factory possess an area of more than 50000 meters square, which contains the office building, production facilities, labs and R&D center. We have more than 100 staff , two-thirds of them are sophisticated technicians who have engaged into chemical synthesis for a long time, and they compose the R&D team of <span class="scayt-misspell" data-scaytid="11" data-scayt_word="Aily">Aily</span> chemicals. This is a highly proficient team of chemists, engineers and technicians. Experience of many years in special chemicals enables us to offer you a variety of complex compounds. <b>From laboratory, pilot plant to large-scale production, we are prepared to execute your highly specialized requirements, including adapting existing units, building additional processing units.</b></font></font></div>
<div align="left"><font size="3" face="Arial">We own sophisticated <span class="scayt-misspell" data-scaytid="17" data-scayt_word="infrostructure">infrostructure</span>, advanced technical know-how and precise analytic instruments, the R&D center and labs are equipped with advanced R&D as well as testing appliances such as<b> GC,<span class="scayt-misspell" data-scaytid="19" data-scayt_word="HPLC">HPLC</span> UV-Vis </b>and so forth. Hence the quality of our products is reliable.</font></div>
<div align="left"><font size="3" face="Arial">We have set up long-term and stable cooperation with some world top companies. In order to improve the quality of the currents products, develop more new products and cultivate custom manufacture, we are making the best of the talents of its own technicians, meanwhile it has built stable cooperation with a large number of universities and institutes.</font></div>
<p>
Basic Information
- Company Name:NANJING AILY BIOTECHNOLOGY CO.,LTD
- Number of Employees:
- Contact person:chen
- Street Address:B-313,No.26,Fu Hou Gang,Gu Lou District, Nanjing 210009,China
- City:nanjing
- Province/State:jiangsu
- Country/Region:China (Mainland)
- Zip:210009
- Business type:Lab/Research institutions
- Tel:+86-25-83208295
- Fax:+86-25-83208202
- Website:
- Year Established: