• Name

  1,2-PROPANEDIOL DIBENZOATE

• EINECS 242-894-7
• CAS No. 19224-26-1
• Article Data19
• CAS DataBase
• Density 1.169 g/cm³
• Solubility 7.7mg/L at 20℃
• Melting Point -3 °C(lit.)
• Formula C₁₇H₁₆O₄
• Boiling Point 385.5 °C at 760 mmHg
• Molecular Weight 284.312
• Flash Point 206.7 °C
• Transport Information
• Appearance
• Safety
• Risk Codes
• Molecular Structure
• Hazard Symbols
• Synonyms 1,2-Propanediol,dibenzoate (6CI,8CI,9CI);1,2-Propylene glycol dibenzoate;Benzoflex 284;Propylene glycol dibenzoate;Bis(benzoic acid)propane-1,2-diyl ester;2-(Benzoyloxy)propyl benzoate;
• PSA 52.60000
• LogP 3.08890

Synthetic route

57-55-6

propylene glycol

65-85-0

benzoic acid

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With Sb2(OCH2CH2O)3 at 180℃; for 30h;	94%
sulfonic acid at 120 - 225℃;
at 120 - 225℃;

613-90-1

benzoyl cyanide

57-55-6

propylene glycol

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With dmap; 1-ethylene glycol monomethyl ether-3-methylimidazolium methanesulfonate at 25 - 35℃;	92%

57-55-6

propylene glycol

93-97-0

benzoic acid anhydride

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With N-ethyl-N,N-diisopropylamine In acetonitrile at 40℃; for 8h;	85%

57-55-6

propylene glycol

3277-27-8

diethyl benzoylphosphonate

A

51591-52-7

1-hydroxyprop-2-yl benzoate

B

37086-84-3

2-hydroxypropyl benzoate

C

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane for 0.333333h; Product distribution; Ambient temperature;	A 17 % Spectr. B 83 % Spectr. C 8%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane for 0.333333h; Ambient temperature;	A 17 % Spectr. B 83 % Spectr. C 8%
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane for 0.333333h; Ambient temperature; Title compound not separated from byproducts;	A 17 % Spectr. B 83 % Spectr. C 8%

...Expand

78-75-1

1,2-Dibromopropane

532-31-0

silver benzoate

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield

532-31-0

silver benzoate

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With iodine; benzene anschliessend Behandeln mit Propen;

57-55-6

propylene glycol

54769-36-7

N-benzoyloxybenzotriazole

A

51591-52-7

1-hydroxyprop-2-yl benzoate

B

37086-84-3

2-hydroxypropyl benzoate

C

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With triethylamine In dichloromethane for 24h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

57-55-6

propylene glycol

98-88-4

benzoyl chloride

A

51591-52-7

1-hydroxyprop-2-yl benzoate

B

37086-84-3

2-hydroxypropyl benzoate

C

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
multistep reaction: monoacylation of diols with reversed chemoselectivity; other diols; quenching with chlorosilanes;
Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;

...Expand

57-55-6

propylene glycol

65-85-0

benzoic acid

A

51591-52-7

1-hydroxyprop-2-yl benzoate

B

37086-84-3

2-hydroxypropyl benzoate

C

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With triphenylphosphine; diethylazodicarboxylate In tetrahydrofuran for 1h; Product distribution; Mechanism; other asymmetric 1,2-diol;

...Expand

57-55-6

propylene glycol

94-36-0

dibenzoyl peroxide

A

51591-52-7

1-hydroxyprop-2-yl benzoate

B

37086-84-3

2-hydroxypropyl benzoate

C

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With triphenylphosphine In dichloromethane for 1h; Product distribution; Mechanism; Ambient temperature; other diols, other benzoylating agent;

...Expand

98-88-4

benzoyl chloride

(+-)-propylene glycol

(+-)-propylene glycol

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With pyridine

98-88-4

benzoyl chloride

lead sulfide

lead sulfide

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 85 percent / Et3N / CH2Cl2 / 0.33 h 2: Et3N / CH2Cl2 / 24 h / Ambient temperature View Scheme

455-32-3

benzoyl fluoride

C21H26O2Si

A

2-((1,3-diphenylprop-2-yn-1-yl)oxy)propyl benzoate

B

19224-26-1

1,2-bis-benzoyloxy-propane

Conditions

Conditions	Yield
With dmap In chloroform-d1 at 20℃; Inert atmosphere; Overall yield = 30.6 mg;

...Expand

19224-26-1

1,2-bis-benzoyloxy-propane

A

113566-74-8

[(1R)-2-hydroxy-1-methyl-ethyl]benzoate

B

113566-73-7

(S)-1-hydroxypropan-2-yl benzoate

Conditions

Conditions	Yield
With octanol; Pseudomonas sp. lipase PS*celite In di-isopropyl ether at 20℃; Product distribution; Further Variations:; Reagents;

1,2-Propanediol,1,2-dibenzoate Specification