-
Name
Doxefazepam
- EINECS
- CAS No. 40762-15-0
- Article Data3
- CAS DataBase
- Density 1.45g/cm3
- Solubility
- Melting Point
- Formula C17H14 Cl F N2 O3
- Boiling Point 618.4°Cat760mmHg
- Molecular Weight 348.761
- Flash Point 327.8°C
- Transport Information
- Appearance
- Safety Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by an unspecified route: somnolence. When heated to decomposition it emits very toxic fumes of Cl−, F−, and NOx.
- Risk Codes
-
Molecular Structure
- Hazard Symbols
- Synonyms 1-(2-Hydroxyethyl)-3-hydroxy-7-chloro-1,3-dihydro-5-(o-fluorophenyl)-2H-1,4-benzodiazepin-2-one;Doxans; Doxefazepam; N-1-Hydroxyethyl-3-hydroxyflurazepam; SAS 643
- PSA 73.13000
- LogP 1.47440
1,3-DIHYDRO-7-CHLORO-5-(o-FLUORO-PHENYL)-3-HYDROXY-1-(2-HYDROXY-ETHYL)-2H-1,4-BENZODIAZEPIN-2-ONE Toxicity Data With Reference
| 1. | unr-hmn TDLo:71 µg/kg:CNS | DRFUD4 Drugs of the Future. 3 (1978),145. | ||
| 2. | orl-rat LD50:2550 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1294. | ||
| 3. | ipr-rat LD50:586 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 25 (1975),1294. | ||
| 4. | ipr-mus LD50:760 mg/kg | JPPMAB Journal of Pharmacy and Pharmacology. 26 (1974),566. |
1,3-DIHYDRO-7-CHLORO-5-(o-FLUORO-PHENYL)-3-HYDROXY-1-(2-HYDROXY-ETHYL)-2H-1,4-BENZODIAZEPIN-2-ONE Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. Human systemic effects by an unspecified route: somnolence. When heated to decomposition it emits very toxic fumes of Cl−, F−, and NOx.
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