Product Name

  • Name

    1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL

  • EINECS
  • CAS No. 488-41-5
  • Article Data17
  • CAS DataBase
  • Density 2.117g/cm3
  • Solubility
  • Melting Point 176-178°
  • Formula C6H12 Br2 O4
  • Boiling Point 511.2°Cat760mmHg
  • Molecular Weight 307.967
  • Flash Point 263°C
  • Transport Information
  • Appearance
  • Safety Moderately toxic by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Br.
  • Risk Codes 45-22
  • Molecular Structure Molecular Structure of 488-41-5 (1,6-DIBROMO-1,6-DIDEOXY-D-MANNITOL)
  • Hazard Symbols
  • Synonyms Mannitol,1,6-dibromo-1,6-dideoxy-, D- (8CI); 1,6-Dibromo-1,6-dideoxy-D-mannitol;1,6-Dibromo-1,6-dideoxymannitol; 1,6-Dibromo-D-mannitol; 1,6-Dibromomannitol;1,6-Dideoxy-1,6-dibromo-D-mannitol; D-Dibromomannitol; DBM; Dibromannit;Dibromannitol; Dibromomannitol; Mielobromol; Mitobronitol; Myebrol;Myelobromol; NCI C04762; NSC 94100; NSC 94110; R 54
  • PSA 80.92000
  • LogP -0.78020

1,6-Dibromomannitol Chemical Properties

Product Name: 1,6-Dibromomannitol 
CAS Registry Number: 488-41-5 
Synonyms: 1,6-Dibrom-1,6-didesoxy-D-mannit ; 1,6-Dibrom-1,6-didesoxy-D-mannit [German] ; 1,6-Dibromo-1,6-D-didesoxymannitol ; 1,6-Dibromo-1,6-dideoxy-D-mannitol ; 1,6-Dibromo-1,6-dideoxymannitol ; 1,6-Dibromo-D-mannitol ; 1,6-Dibromomannitol ; 1,6-Dideoy-1,6-dibromo-D-mannitol ; 3-01-00-02373 (Beilstein Handbook Reference) ; AI3-52331 ; BRN 1721919 ; CCRIS 2750 ; DBM ; Dibromannit ; Dibromannitol ; Dibromomannitol ; EINECS 207-676-8 ; Mielobromol ; Mitobronitol ; Mitobronitolum ; Mitobronitolum [INN-Latin] ; Myebrol ; Myelobromol ; NCI-C04762 ; NSC-94100 ; R 54 ; UNII-5UP30YED7N 
Systematic Name: 1,6-Dibromo-1,6-dideoxy-D-mannitol ; D-Mannitol, 1,6-dibromo-1,6-dideoxy- ; Mannitol, 1,6-dibromo-1,6-dideoxy-, D- ; Mitobronitol 
IUPAC Name: (2R,3S,4S,5R)-1,6-dibromohexane-2,3,4,5-tetrol
Molecular Weight: 307.96508 [g/mol]
Molecular Formula: C6H12Br2O4
XLogP3: -0.3
H-Bond Donor: 4
H-Bond Acceptor: 4
EINECS: 207-676-8 
Surface Tension: 77.4 dyne/cm
Density: 2.117 g/cm3
Flash Point: 263 °C
Enthalpy of Vaporization: 90.04 kJ/mol
Boiling Point: 511.2 °C at 760 mmHg
Vapour Pressure: 1.37E-12 mmHg at 25°C 
Product Categories: Carbohydrates;Carbohydrates A to;Carbohydrates D-FBiochemicals and Reagents;Monosaccharide
Following is the molecular structure of 1,6-Dibromomannitol (CAS NO.488-41-5) is:

1,6-Dibromomannitol Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 900mg/kg (900mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 831, 1972.
mouse LD50 intravenous 2200mg/kg (2200mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 680, 1977.
mouse LD50 oral 1380mg/kg (1380mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 831, 1972.
mouse LD50 subcutaneous 2200mg/kg (2200mg/kg) BEHAVIORAL: TREMOR

BEHAVIORAL: ATAXIA

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 831, 1972.
rabbit LD50 oral 1080mg/kg (1080mg/kg)   Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 831, 1972.
rat LD50 intraperitoneal 900mg/kg (900mg/kg) BLOOD: NORMOCYTIC ANEMIA

BLOOD: THROMBOCYTOPENIA
European Journal of Cancer. Vol. 4, Pg. 617, 1968.
rat LD50 intravenous 1370mg/kg (1370mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 680, 1977.
rat LD50 oral 1500mg/kg (1500mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: OTHER CHANGES

BLOOD: NORMOCYTIC ANEMIA
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 831, 1972.
rat LD50 subcutaneous 1240mg/kg (1240mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"

GASTROINTESTINAL: OTHER CHANGES

BLOOD: NORMOCYTIC ANEMIA
Oyo Yakuri. Pharmacometrics. Vol. 6, Pg. 831, 1972.

1,6-Dibromomannitol Consensus Reports

NCI Carcinogenesis Bioassay Completed; Results Positive: mouse, rat ( RRCRBU    Recent Results in Cancer Research. 52 (1975),1. ).

1,6-Dibromomannitol Safety Profile

Safty information about 1,6-Dibromomannitol (CAS NO.488-41-5) is:
Moderately toxic by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Questionable carcinogen with experimental carcinogenic and neoplastigenic data. Experimental teratogenic and reproductive effects. Human mutation data reported. When heated to decomposition it emits toxic fumes of Br
Hazard Codes:
ToxicT
Risk Statements:
R45:May cause cancer. 
R22:Harmful if swallowed.
Safety Statements:
S53:Avoid exposure - obtain special instructions before use. 
S22:Do not breathe dust. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection. 
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
WGK Germany: 3
RTECS: OP2800000

1,6-Dibromomannitol Specification

General Description about 1,6-Dibromomannitol (CAS NO.488-41-5) ,it is a white powder. It insoluble in water. And it is a halogenated alcohol. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert them to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides.Also it is probably combustible.

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