1-Deoxynojirimycin supplier | CasNO.19130-96-2

Name
1-Deoxynojirimycin
EINECS 606-239-2
CAS No. 19130-96-2
Article Data102
CAS DataBase
Density 1.456 g/cm³
Solubility soluble in water
Melting Point 195-196 °C
Formula C₆H₁₃NO₄
Boiling Point 361.1 °C at 760 mmHg
Molecular Weight 163.174
Flash Point 197.3 °C
Transport Information
Appearance white crystalline solid
Safety 24/25
Risk Codes R36/37/38
Molecular Structure
Hazard Symbols Xi
Synonyms UNII-FZ56898FLE;1,5-Deoxy-1,5-imino-D-mannitol;
PSA 92.95000
LogP -2.63800

Synthetic route

: 69567-11-9, 76738-52-8, 126836-30-4
2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride; 20% palladium hydroxide-activated charcoal; hydrogen In methanol; water for 14h;	100%
With hydrogenchloride; palladium 10% on activated carbon; hydrogen In ethanol; water at 20℃; under 3000.3 Torr; for 20h; pH=Ca. 2;	93%
Stage #1: 2,3,4,6-tetra-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol With hydrogenchloride In ethanol for 0.25h; pH=Ca. 2; Inert atmosphere; Stage #2: With palladium 10% on activated carbon; hydrogen In ethanol under 3000.3 Torr; for 20h; Inert atmosphere;	93%

: 157363-86-5
N-benzyl-3,4-di-O-benzyl-1,5-dideoxy-1,5-imino-D-glucitol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; palladium In acetic acid for 15h;	100%
With hydrogen; acetic acid; palladium for 18h;	100%
With palladium 10% on activated carbon; hydrogen In acetic acid at 20℃; for 19h;	98%

: 1190302-84-1
(2R,4aR,7S,8R,8aR)-tert-butyl 8-hydroxy-7-(methoxymethyl)-2-phenyltetrahydro-4H-[1,3]dioxino[5,4-b]pyridine-5(4aH)-carboxylate

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride In ethanol for 18h; Reflux; Inert atmosphere;	100%

: 132198-14-2
N-Benzhydryl-1-deoxynojirimycin

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; palladium dihydroxide In methanol under 3102.9 Torr; for 24h;	99%
With hydrogen; palladium dihydroxide	90%
With hydrogen; palladium on activated charcoal In methanol	50%

: 4-benzyloxy-2-hydroxymethylpiperidine-3,5-diol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In tetrahydrofuran; water at 20℃; under 760.051 Torr; for 48h;	98%
With hydrogen; palladium dihydroxide In methanol for 24h;

: 15218-38-9
nojirimycin

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; platinum(IV) oxide In ethanol; water under 750.06 Torr; for 18h; Ambient temperature;	97%

: (2R,3R,4R,5S)-3-benzoyloxy-1-benzyloxycarbonyl-4,5-diacetoxy-2-(hydroxymethyl)piperidine

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride In methanol for 12h; Heating;	94%

: 1017587-22-2
(2R,3R,4R,5S)-(3,4-dibenzyloxy-N-tert-butoxycarbonyl-5-hydroxy-2-piperidinyl)methanol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride; hydrogen; palladium on activated charcoal In ethanol at 20℃; for 48h;	92%

: 1,3,6-Tri-O-benzyl-5-(benzyloxycarbonylamino)-5-deoxy-α,β-D-gluco-furanose

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; palladium dihydroxide In acetic acid; tert-butyl alcohol under 3750.3 Torr; for 48h; Ambient temperature;	91%

: 149302-60-3
N-bentyl-2,3,4,6-tetra-O-benzyl-1-deoxynojirimycin

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With 10 wt% Pd(OH)2 on carbon; hydrogen In ethanol; chloroform at 20℃; for 20h;	91%

: 108818-06-0
(2R,3R,4S,5S)-4,5-(isopropylenedioxy)-3-(methoxymethoxy)-2-<(methoxymethoxy)methyl>piperidine

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride In methanol for 1h; Heating;	90%

: 107025-38-7
(3aS,6R,7R,7aS)-6-(tert-Butyl-dimethyl-silanyloxymethyl)-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridin-7-ol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With trifluoroacetic acid Ambient temperature;	90%

: 72458-46-9
N-benzyl-1-deoxynojirimycin

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In ethanol	89%

: C8H12F3NO6

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With 10 wt% Pd(OH)2 on carbon; hydrogen; potassium carbonate In water under 2585.81 Torr;	80%

: 123149-59-7, 132152-32-0
Nojirimycin bisulfite

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With barium dihydroxide; hydrogen; nickel In water	75%

: 75016-28-3
((2S,3R,4S)-2,3,4,6-Tetrahydroxy-5-oxo-hexyl)-carbamic acid benzyl ester

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; potassium carbonate; palladium on activated charcoal In methanol; water at 60℃; under 60004.8 Torr; for 2h;	75%
With palladium 10% on activated carbon; hydrogen In methanol; water at 20℃; under 2585.81 Torr; for 24h;	717 mg

: 1427467-92-2
(2R,3R,4R,5S)-3-benzyloxy-2-benzyloxymethyl-4,5-isopropylidenedioxypiperidine

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride; palladium 10% on activated carbon; water; hydrogen In methanol; ethyl acetate at 20℃; for 48h;	75%

: 74244-24-9
6-Amino-6-desoxy-L-sorbofuranose-hydrochlorid

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With platinum(IV) oxide; hydrogen at 20℃; under 3750.38 Torr; for 16h; Inert atmosphere;	70%

: methyl 5-C-benzyloxy-β-D-xylo-hexopyranoside

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With 20 % Pd(OH)2/C; ammonium acetate; hydrogen In methanol; water at 20℃; for 24h;	68%

: 223421-29-2
(+)-(3aR,5RS,6R,6aS)-3a,5,6,6a-tetrahydro-5,6-dihydroxyfuro<2,3-d>isoxazole-3-methanol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol at 25℃; under 750.06 Torr; for 15h;	65%

: 146897-25-8
5-azido-5-deoxy-D-glucofuranose

A: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

B: 73285-50-4, 73465-43-7, 75172-81-5, 118464-54-3, 126663-84-1, 126923-63-5, 136658-34-9
1-deoxynojirimycin hydrochloride

Conditions

Conditions	Yield
Stage #1: 5-azido-5-deoxy-D-glucofuranose With palladium 10% on activated carbon; hydrogen In water at 20℃; under 2068.65 - 2585.81 Torr; Stage #2: With hydrogenchloride In water pH=2;	A 16% B 56%

: (2R,3R,4S)-2-Benzyloxymethyl-3,4,5,6-tetrahydroxy-piperidine-1-carboxylic acid benzyl ester

A: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

B: 14199-63-4, 16647-80-6, 19130-96-2, 84444-90-6, 84518-54-7, 108147-54-2, 117821-07-5, 126663-71-6, 135246-66-1, 135395-59-4, 143406-74-0, 146747-37-7
1-deoxymannojirimycin

Conditions

Conditions	Yield
With hydrogenchloride; hydrogen; palladium dihydroxide	A 55% B 21%

: 5-Azido-2,3-di-O-benzyl-5-desoxy-D-glucofuranose

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogenchloride; hydrogen; palladium on activated charcoal In 1,4-dioxane; water for 24h; Ambient temperature;	54%

: 81703-56-2
5-amino-5-deoxy-D-glucose-1-sulfonic acid

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With barium hydroxide octahydrate; hydrogen; Raney-Ni (W-4) In water under 760 Torr; for 8h; Ambient temperature;	53%

: 1051942-01-8
(2R,3R,4S,5S)-5-(Benzyloxy)-2-(hydroxymethyl)piperidine-3,4-diol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With palladium 10% on activated carbon; hydrogen In methanol at 20℃;	53%

: 768387-39-9
(1R,3aR,7aR,8R)-6,6-dimethylhexahydro-1,5,7-trioxa-3-azacyclopropa[a]naphthalene-3-carboxylic acid tert-butyl ester

A: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

B: 1,5-dideoxy-1,5-imino-(2R,3S,4R,5R)-D-altritol

Conditions

Conditions	Yield
Stage #1: (1R,3aR,7aR,8R)-6,6-dimethylhexahydro-1,5,7-trioxa-3-azacyclopropa[a]naphthalene-3-carboxylic acid tert-butyl ester With potassium hydroxide In 1,4-dioxane; water Heating; Stage #2: With hydrogenchloride In methanol; water at 60℃; for 1h; Stage #3: With DOWEX-1X2 (OH(1-) form) In water Further stages.;	A 33% B 51%

: (3S,4R,5R,6R)-6-Azido-2-hydroxymethyl-2-methoxy-tetrahydro-pyran-3,4,5-triol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

Conditions

Conditions	Yield
With hydrogen; palladium dihydroxide In ethanol under 25857.4 Torr; for 24h;	19%

: 127708-83-2
3,6-di-O-benzyl-5-azido-5-deoxy-α/β-D-glucofuranose

A: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

B: 14199-63-4, 16647-80-6, 19130-96-2, 84444-90-6, 84518-54-7, 108147-54-2, 117821-07-5, 126663-71-6, 135246-66-1, 135395-59-4, 143406-74-0, 146747-37-7
1-deoxymannojirimycin

Conditions

Conditions	Yield
With hydrogen; palladium hydroxide - carbon In methanol; water; acetic acid under 3800 Torr; for 48h; Ambient temperature; Yield given;	A n/a B 5%
With hydrogen; palladium hydroxide - carbon In methanol; water; acetic acid under 3800 Torr; for 48h; Ambient temperature; Yields of byproduct given;	A n/a B 5%

: 57-04-5
dihydroxyacetone phosphate

: 114395-07-2
(RS)-3-azido-2-hydroxypropanal

A: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

B: 14199-63-4, 16647-80-6, 19130-96-2, 84444-90-6, 84518-54-7, 108147-54-2, 117821-07-5, 126663-71-6, 135246-66-1, 135395-59-4, 143406-74-0, 146747-37-7
1-deoxymannojirimycin

Conditions

Conditions	Yield
Multistep reaction;

...Expand

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 958880-39-2
C12H15N5O3

: (2R,3R,4R,5S)-1-(6-((4-azido-2-nitrophenyl)amino)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
With sodium cyanoborohydride; acetic acid In methanol at 20℃; for 14h;	100%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 73285-50-4, 73465-43-7, 75172-81-5, 118464-54-3, 126663-84-1, 126923-63-5, 136658-34-9
1-deoxynojirimycin hydrochloride

Conditions

Conditions	Yield
With hydrogenchloride In water	100%
With hydrogenchloride In water at 10℃; pH=2; Molecular sieve;

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 76911-01-8
5-hexynyl p-toluenesulfonate

: C12H21NO4

Conditions

Conditions	Yield
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 24h; Inert atmosphere;	99%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-44-7
C13H18O2

: 1383152-03-1
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(m-tolyloxy)hexyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H18O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	98%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383152-78-0
C12H16O2

: 1383152-95-1
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(3-(2-propoxyphenyl)propyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C12H16O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen for 24h;	97%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383152-81-5
C12H16O2

: 1383152-98-4
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(3-(3-propoxyphenyl)propyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C12H16O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	97%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1057671-19-8
C12H16O2

: 1383153-01-2
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(3-(4-propoxyphenyl)propyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C12H16O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	97%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 91476-10-7
3-bromoprop-1-ene-2-phosphonic acid diethyl ester

: 165805-33-4
[1-((2R,3R,4R,5S)-3,4,5-Trihydroxy-2-hydroxymethyl-piperidin-1-ylmethyl)-vinyl]-phosphonic acid diethyl ester

Conditions

Conditions	Yield
With sodium hydrogencarbonate In acetone at 25℃; for 3h;	96%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-58-3
C12H15FO2

: 1383152-21-3
(2R,3R,4R,5S)-1-(6-(2-fluorophenoxy)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C12H15FO2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon In ethanol for 24h;	96%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1369796-75-7
6-(3-fluorophenoxy)hexanal

: 1383152-24-6
(2R,3R,4R,5S)-1-(6-(3-fluorophenoxy)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: 6-(3-fluorophenoxy)hexanal With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	96%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 289032-98-0
C12H15FO2

: 1383152-27-9
(2R,3R,4R,5S)-1-(6-(4-fluorophenoxy)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C12H15FO2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	96%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-81-2
C13H15F3O2

: 1383152-45-1
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(4-(trifluoromethyl)phenoxy)hexyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H15F3O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	96%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383152-89-3
C15H20O2

: 1383153-07-8
(2R,3R,4R,5S)-1-(3-(3-(cyclohexyloxy)phenyl)propyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C15H20O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 20h;	96%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-49-2
C16H24O2

: 1383152-12-2
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(2-isopropyl-5-methylphenoxy)hexyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C16H24O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	95%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383152-92-8
C15H20O2

: 1383153-10-3
(2R,3R,4R,5S)-1-(3-(4-(cyclohexyloxy)phenyl)propyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C15H20O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	95%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-78-7
C13H15F3O2

: 1383152-42-8
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(3-(trifluoromethyl)phenoxy)hexyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H15F3O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	94%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-84-5
C13H15F3O3

: 1383152-48-4
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(4-(trifluoromethoxy)phenoxy)hexyl) piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H15F3O3 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	94%

: 50-00-0
formaldehyd

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 69567-10-8
N-methyldeoxynojirimycin

Conditions

Conditions	Yield
With hydrogen; palladium on activated charcoal In methanol; water under 2585.7 Torr; for 36h;	93%
With formic acid In water for 20h; Heating; Yield given;
With formic acid at 80℃; for 3h;

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-75-4
C13H15F3O2

: 1383152-39-3
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(2-(trifluoromethyl)phenoxy)hexyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H15F3O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	93%
With sodium cyanoborohydride In methanol

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383151-90-3
C13H18O3

: 1383152-54-2
(2R,3R,4R,5S)-2-(hydroxymethyl)-1-(6-(4-methoxyphenoxy)hexyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H18O3 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	93%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383149-90-3
C13H26O2

: 1383150-05-7
(2R,3R,4R,5S)-1-(6-(heptan-4-yloxy)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H26O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon In ethanol for 24h;	93%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383153-50-1
C14H26O2

: 1383150-14-8
(2R,3R,4R,5S)-1-(6-((2-ethylcyclohexyl)oxy)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C14H26O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	93%

: 19130-96-2
1,5-dideoxy-1,5-imino-D-glucitol

: 1383153-78-3
C13H24O2

: 1383150-37-5
(2R,3R,4R,5S)-1-(6-(cycloheptyloxy)hexyl)-2-(hydroxymethyl)piperidine-3,4,5-triol

Conditions

Conditions	Yield
Stage #1: 1,5-dideoxy-1,5-imino-D-glucitol With acetic acid at 20℃; Stage #2: C13H24O2 With acetic acid In ethanol at 20℃; for 1h; Inert atmosphere; Stage #3: With palladium 10% on activated carbon; hydrogen In ethanol for 24h;	93%

1-Deoxynojirimycin Chemical Properties

Molecular structure of 1-Deoxynojirimycin (CAS NO.19130-96-2) is:

Product Name: 1-Deoxynojirimycin
CAS Registry Number: 19130-96-2
IUPAC Name: (2R,3R,4R,5S)-2-(hydroxymethyl)piperidine-3,4,5-triol
Molecular Weight: 163.17172 [g/mol]
Molecular Formula: C₆H₁₃NO₄
XLogP3-AA: -2.3
H-Bond Donor: 5
H-Bond Acceptor: 5
Flash Point: 163.7 °C
Enthalpy of Vaporization: 64.97 kJ/mol
Boiling Point: 347 °C at 760 mmHg
Vapour Pressure: 9.72E-06 mmHg at 25°C
Melting Point: 195-196 °C
Product Categories: Miscellaneous Natural Products; All Inhibitors; Glycosidase Inhibitors; Inhibitors; Miscellaneous Enzyme

1-Deoxynojirimycin Uses

1-Deoxynojirimycin (CAS NO.19130-96-2) is an alpha-glucosidase inhibitor with antiviral action.

1-Deoxynojirimycin Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
rat	LD50	oral	> 5gm/kg (5000mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED SKIN AND APPENDAGES (SKIN): HAIR: OTHER	International Journal of Toxicology. Vol. 16(Suppl,

1-Deoxynojirimycin Specification

1-Deoxynojirimycin , its cas register number is 19130-96-2. It also can be called 1,5-Deoxy-1,5-imino-D-mannitol ; 1-Deoxymannojirimycin ; UNII-FZ56898FLE ; 3,4,5-Piperidinetriol, 2-(hydroxymethyl)-, (2R-(2alpha,3beta,4alpha,5beta))- .It is a white crystalline solid.

Product Name

1-Deoxynojirimycin

Synthetic route

1-Deoxynojirimycin Chemical Properties

1-Deoxynojirimycin Uses

1-Deoxynojirimycin Toxicity Data With Reference

1-Deoxynojirimycin Specification

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