1-AMINO-4-(2-HYDROXYETHYL)PIPERAZINE

The 1-Piperazineethanol,4-amino-, with the CAS registry number 3973-70-4, is also known as 4-Amino-1-piperazineethanol. Its EINECS number is 223-603-2. It belongs to the product category of API Intermediates. This chemical's molecular formula is C₆H₁₅N₃O and molecular weight is 145.20. What's more, its IUPAC name is 2-(4-Aminopiperazin-1-yl)ethanol. It is stable at room temperature and pressure, and it should be sealed and stored in a cool and dry place and be protected from oxidizes.

Physical properties of 1-Piperazineethanol,4-amino- are: (1)ACD/LogP: -1.66; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.37; (4)ACD/LogD (pH 7.4): -1.85; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1.9; (9)#H bond acceptors: 4; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 4; (12)Polar Surface Area: 18.95 Å²; (13)Index of Refraction: 1.521; (14)Molar Refractivity: 39.99 cm³; (15)Molar Volume: 131.2 cm³; (16)Polarizability: 15.85×10^-24 cm³; (17)Surface Tension: 45.1 dyne/cm; (18)Density: 1.106 g/cm³; (19)Flash Point: 119 °C; (20)Enthalpy of Vaporization: 59.38 kJ/mol; (21)Boiling Point: 273.1 °C at 760 mmHg; (22)Vapour Pressure: 0.000751 mmHg at 25 °C.

Uses of 1-Piperazineethanol,4-amino-: it can be used to produce 1-bis(trimethylsilyl)amino-4-[2-(trimethylsiloxy)ethyl]piperazine at the ambient temperature. It will need reagent KH and solvents tetrahydrofuran and hexamethylphosphoric acid triamide with the reaction time of 72 hours. The yield is about 70%.

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable gloves and eye/face protection.

You can still convert the following datas into molecular structure:
(1)Canonical SMILES: C1CN(CCN1CCO)N
(2)InChI: InChI=1S/C6H15N3O/c7-9-3-1-8(2-4-9)5-6-10/h10H,1-7H2
(3)InChIKey: XAOHWSFGKCJOGT-UHFFFAOYSA-N