Product Name

  • Name

    1-Propanethiol

  • EINECS 203-455-5
  • CAS No. 107-03-9
  • Article Data79
  • CAS DataBase
  • Density 0.826 g/cm3
  • Solubility immiscible with water
  • Melting Point -113 °C
  • Formula C3H8S
  • Boiling Point 67.8 °C at 760 mmHg
  • Molecular Weight 76.1625
  • Flash Point -20 °C
  • Transport Information UN 2402 3/PG 2
  • Appearance clear colourless liquid
  • Safety 16-26-39-57-36/37/39-29
  • Risk Codes 11-41-50-36/37/38-21/22
  • Molecular Structure Molecular Structure of 107-03-9 (1-Propanethiol)
  • Hazard Symbols FlammableF, HarmfulXn, DangerousN
  • Synonyms 1-Mercaptopropane;1-Propyl mercaptan;1-Propylthiol;Propyl mercaptan;Propylthiol;n-Propanethiol;n-Propyl mercaptan;n-Propylthiol;
  • PSA 38.80000
  • LogP 1.32620

Synthetic route

tripropyl phosphorotrithioite
869-56-7

tripropyl phosphorotrithioite

benzene-1,2-diol
120-80-9

benzene-1,2-diol

A

2,2-'spirobi(1,3,2-benzodioxaphosphole)
181-85-1

2,2-'spirobi(1,3,2-benzodioxaphosphole)

B

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
at 90 - 95℃; under 0.02 Torr; for 0.5h;A 72%
B 96%
ethylene glycol
107-21-1

ethylene glycol

N,N-tetraethyldiamidothiophosphite S-propyl

N,N-tetraethyldiamidothiophosphite S-propyl

A

1-thiopropane
107-03-9

1-thiopropane

B

1,4,6,9-tetraoxa-5λ5-phosphaspiro[4,4]nonane
3646-10-4, 54515-09-2, 673460-28-1

1,4,6,9-tetraoxa-5λ5-phosphaspiro[4,4]nonane

C

diethylamine
109-89-7

diethylamine

Conditions
ConditionsYield
at 120 - 130℃; for 1h;A n/a
B 90%
C n/a
at 120 - 130℃; for 1h; Product distribution;A n/a
B 90%
C n/a
dipropyl phenylphosphoramidodithioite
84839-06-5

dipropyl phenylphosphoramidodithioite

A

1-thiopropane
107-03-9

1-thiopropane

B

tripropyl phosphorotrithioite
869-56-7

tripropyl phosphorotrithioite

C

aniline
62-53-3

aniline

Conditions
ConditionsYield
at 175 - 180℃; for 10h;A 0.7 g
B 89%
C 71%
at 175 - 180℃; for 10h; Product distribution; other reagent: water; presence of solvent: dioxane; other temperature and reaction time.;A 0.7 g
B 89%
C 71%
propyl bromide
106-94-5

propyl bromide

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
Stage #1: propyl bromide With thiourea In ethanol for 3h; Heating;
Stage #2: With sodium hydroxide In ethanol for 2h; Heating;
86%
With potassium hydroxide; hydrogen sulfide
With hydrogen sulfide; sodium ethanolate zuletzt bei Siedetemperatur;
With ethanol; potassium hydrosulfide
With thiourea In ethanol Reflux;
phenyl isothiocyanate
103-72-0

phenyl isothiocyanate

dipropyl phenylphosphoramidodithioite
84839-06-5

dipropyl phenylphosphoramidodithioite

A

1-thiopropane
107-03-9

1-thiopropane

B

tripropyl phosphorotrithioite
869-56-7

tripropyl phosphorotrithioite

C

N,N-diphenylthiourea
102-08-9

N,N-diphenylthiourea

Conditions
ConditionsYield
In hexane for 3h; Heating;A n/a
B 83%
C 59%
1-propyl carbamate
627-12-3

1-propyl carbamate

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
With tetraphosphorus decasulfide In toluene for 2h; Reflux;78%
dipropyl diethylphosphoramidodithioite
53431-44-0

dipropyl diethylphosphoramidodithioite

benzene-1,2-diol
120-80-9

benzene-1,2-diol

A

1-thiopropane
107-03-9

1-thiopropane

B

diethylammonium tris(o-phenylenedioxy)phosphate

diethylammonium tris(o-phenylenedioxy)phosphate

Conditions
ConditionsYield
at 65℃; in the vacuum of an oil pump;A 75%
B 77%
dipropyl phenylphosphoramidodithioite
84839-06-5

dipropyl phenylphosphoramidodithioite

A

1-thiopropane
107-03-9

1-thiopropane

B

tripropyl phosphorotrithioite
869-56-7

tripropyl phosphorotrithioite

C

anilinium dihydrogen phosphite
33921-12-9

anilinium dihydrogen phosphite

D

aniline
62-53-3

aniline

Conditions
ConditionsYield
With water In 1,4-dioxane for 72h; Further byproducts given;A n/a
B 61%
C 67%
D 26%
4-Hydroxy-4-methyl-2-pentanone
123-42-2

4-Hydroxy-4-methyl-2-pentanone

Ethylthiophosphinsaeure-propylester-chlorid
16543-44-5

Ethylthiophosphinsaeure-propylester-chlorid

A

1-thiopropane
107-03-9

1-thiopropane

B

2-ethyl-3,3,5-trimethyl-1,2-oxaphosphol-4-ene 2-oxide
19016-65-0

2-ethyl-3,3,5-trimethyl-1,2-oxaphosphol-4-ene 2-oxide

C

(1,1-Dimethyl-3-oxo-butyl)-ethyl-phosphinothioic acid S-propyl ester
51805-02-8

(1,1-Dimethyl-3-oxo-butyl)-ethyl-phosphinothioic acid S-propyl ester

Conditions
ConditionsYield
A 10%
B 11%
C 56%
1,4-di(n-propyl)tetrasulfane
52687-98-6

1,4-di(n-propyl)tetrasulfane

A

1,2-dithiole-3-thione
534-25-8

1,2-dithiole-3-thione

B

1-thiopropane
107-03-9

1-thiopropane

C

propyl sulfide
111-47-7

propyl sulfide

D

Dipropyl disulfide
629-19-6

Dipropyl disulfide

Conditions
ConditionsYield
at 350℃;A 52%
B 14%
C 4%
D 15%
4-Hydroxy-4-methyl-2-pentanone
123-42-2

4-Hydroxy-4-methyl-2-pentanone

S-propylphenylchlorothiophosphonite
23675-87-8

S-propylphenylchlorothiophosphonite

A

1-thiopropane
107-03-9

1-thiopropane

B

3,3,5-trimethyl-2-phenyl-1,2-oxaphospholene 2-oxide
4529-76-4

3,3,5-trimethyl-2-phenyl-1,2-oxaphospholene 2-oxide

C

(1,1-Dimethyl-3-oxo-butyl)-phenyl-phosphinothioic acid S-propyl ester
76622-01-0

(1,1-Dimethyl-3-oxo-butyl)-phenyl-phosphinothioic acid S-propyl ester

Conditions
ConditionsYield
A 43%
B 46%
C 25%
dipropyl trisulfide*dipropyl tetrasulfide

dipropyl trisulfide*dipropyl tetrasulfide

A

1,2-dithiole-3-thione
534-25-8

1,2-dithiole-3-thione

B

1-thiopropane
107-03-9

1-thiopropane

C

propyl sulfide
111-47-7

propyl sulfide

D

Dipropyl disulfide
629-19-6

Dipropyl disulfide

Conditions
ConditionsYield
at 350℃;A 44%
B 13%
C 3%
D 7%
propan-1-ol
71-23-8

propan-1-ol

aluminum sulfide

aluminum sulfide

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
at 310°C;32.5%
dipropyl trisulfide
6028-61-1

dipropyl trisulfide

A

1,2-dithiole-3-thione
534-25-8

1,2-dithiole-3-thione

B

1-thiopropane
107-03-9

1-thiopropane

C

propyl sulfide
111-47-7

propyl sulfide

D

Dipropyl disulfide
629-19-6

Dipropyl disulfide

Conditions
ConditionsYield
at 350℃;A 29%
B 11%
C 2%
D 6%
at 350℃; Product distribution; other polysulfides; var. temp.;
propan-1-ol
71-23-8

propan-1-ol

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
With hydrogen sulfide; thorium dioxide
With aluminum sulfide at 310℃;
With hydrogen sulfide; thorium dioxide at 300 - 360℃;
With sodium sulfide; phosphorus; sodium sulfate bei allmaehlichem Zufliessenlassen von Brom unter maessiger Kuehlung;
propan-1-ol
71-23-8

propan-1-ol

A

1-thiopropane
107-03-9

1-thiopropane

B

O.O-Dipropyl-dithyophosphat
2253-43-2

O.O-Dipropyl-dithyophosphat

Conditions
ConditionsYield
With phosphorous (V) sulfide at 180℃;
propene
187737-37-7

propene

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
With hydrogen sulfide at 0℃; Irradiation.mit UV-Licht;
With hydrogen sulfide; tetraethyllead(IV) Irradiation.mit UV-Licht;
With hydrogen sulfide; acetone Irradiation.mit UV-Licht;
propene
187737-37-7

propene

A

1-thiopropane
107-03-9

1-thiopropane

B

2-propanethiol
75-33-2

2-propanethiol

Conditions
ConditionsYield
With kieselguhr; nickel(II) sulfide; hydrogen sulfide at 250 - 300℃;
With kieselguhr; nickel(II) sulfide; hydrogen sulfide at 250 - 300℃;
S-n-propylisothiourea
2986-21-2

S-n-propylisothiourea

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
With potassium hydroxide
propyl sulfide
111-47-7

propyl sulfide

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
With ammonia; sodium
With hydrogen In acetone at -78℃; under 4 Torr; Mechanism; other alkyl sulfides and alkyl substituted-benzyl sulfides, competition with various alkyl sulfides, rate of disappearance relative to various alkyl sulfides, microwave generation of H from H2, other reagent: atomic deuterium;
benzyl-dithiocarbamic acid propyl ester
16022-38-1

benzyl-dithiocarbamic acid propyl ester

A

1-thiopropane
107-03-9

1-thiopropane

B

Benzyl isothiocyanate
622-78-6

Benzyl isothiocyanate

Conditions
ConditionsYield
Zerfaellt beim Erhitzen im Vakuum oder unter gewoehnlichem Druck;
decylthiol
143-10-2

decylthiol

Dipropyl disulfide
629-19-6

Dipropyl disulfide

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
at 138 - 139℃;
at 180℃;
Dipropyl disulfide
629-19-6

Dipropyl disulfide

1-thiopropane
107-03-9

1-thiopropane

Conditions
ConditionsYield
With 1-methyl-1-propanethiol Equilibrium constant;
With ammonia; sodium
With naphtha at 496℃;
Dipropyl disulfide
629-19-6

Dipropyl disulfide

A

1-thiopropane
107-03-9

1-thiopropane

B

1-(methylthio)-propane
3877-15-4

1-(methylthio)-propane

Conditions
ConditionsYield
bei der Einw. von Penicillium brevicaule Saccardo;
With water bei der Einw. von Penicillium brevicaule Saccardo;
propene
187737-37-7

propene

A

1-thiopropane
107-03-9

1-thiopropane

B

propyl sulfide
111-47-7

propyl sulfide

C

n-propyl isopropyl sulfide
5008-73-1

n-propyl isopropyl sulfide

D

2-propanethiol
75-33-2

2-propanethiol

Conditions
ConditionsYield
With benzophenone; hydrogen sulfide; phosphorous acid trimethyl ester In diethylene glycol dimethyl ether at 10℃; for 4h; Product distribution; Irradiation; variation of reagents and solvents (t. butanol, benzene);
S-propyl 3-oxobutanethioate
15780-61-7

S-propyl 3-oxobutanethioate

A

1-thiopropane
107-03-9

1-thiopropane

B

2-acetoacetic acid
541-50-4

2-acetoacetic acid

Conditions
ConditionsYield
With sodium hydroxide at 25℃; Rate constant; ionic strength 0.1M, 0.8percent (v/v) acetonitrile;
O-ethyl S-n-propyl phenylphosphonothioate
57557-81-0

O-ethyl S-n-propyl phenylphosphonothioate

A

1-thiopropane
107-03-9

1-thiopropane

B

diethyl phenylphosphonate
1754-49-0

diethyl phenylphosphonate

C

ethyl Phenylphosphinate
172487-18-2

ethyl Phenylphosphinate

D

ethyl hydrogen phenylphosphonate
4546-19-4

ethyl hydrogen phenylphosphonate

E

O-ethyl phenylphosphonothioic acid
6230-93-9

O-ethyl phenylphosphonothioic acid

F

Dipropyl disulfide
629-19-6

Dipropyl disulfide

Conditions
ConditionsYield
In ethanol for 0.166667h; Mechanism; Product distribution; Irradiation; variation of time;
S-propyl O-ethyl dithiocarbonate
99115-89-6

S-propyl O-ethyl dithiocarbonate

A

thiophene
188290-36-0

thiophene

B

carbon disulfide
75-15-0

carbon disulfide

C

1-thiopropane
107-03-9

1-thiopropane

D

Dithiocarbonic acid S-ethyl ester S-propyl ester
10596-57-3

Dithiocarbonic acid S-ethyl ester S-propyl ester

Conditions
ConditionsYield
at 500℃; Yield given. Yields of byproduct given;
1-thiopropane
107-03-9

1-thiopropane

acrylonitrile
107-13-1

acrylonitrile

3-(1-propylmercapto)propionitrile
54974-64-0

3-(1-propylmercapto)propionitrile

Conditions
ConditionsYield
With sodium methylate at 0 - 20℃; Michael reaction;100%
With KF/basic alumina In dichloromethane Michael condensation; Sonication;88%
With sodium hydroxide
1-thiopropane
107-03-9

1-thiopropane

N-methyl-N-tert-butyldimethylsilyl-1,1,1-trifluoroacetamide
77377-52-7

N-methyl-N-tert-butyldimethylsilyl-1,1,1-trifluoroacetamide

tert-Butyl-dimethyl-propylsulfanyl-silane
82112-24-1

tert-Butyl-dimethyl-propylsulfanyl-silane

Conditions
ConditionsYield
With tert-butyldimethylsilyl chloride In acetonitrile for 0.0833333h; Product distribution; Ambient temperature; other tert-butyldimethylsilyl- donors; other thiols;100%
With tert-butyldimethylsilyl chloride In acetonitrile for 0.0833333h; Ambient temperature; other silylating agent;100%
1-thiopropane
107-03-9

1-thiopropane

2-cyano-1-phenylacetylene
935-02-4

2-cyano-1-phenylacetylene

3-propylthio-3-phenylacrylonitrile

3-propylthio-3-phenylacrylonitrile

Conditions
ConditionsYield
In ammonia for 1h;100%
1-thiopropane
107-03-9

1-thiopropane

1-ethylsulfinyl-2-nitrocyclopentene
139118-82-4

1-ethylsulfinyl-2-nitrocyclopentene

1-nitro-2-propylthiocyclopentene
191719-96-7

1-nitro-2-propylthiocyclopentene

Conditions
ConditionsYield
With triethylamine In dichloromethane at -78℃; for 0.916667h;100%
1-thiopropane
107-03-9

1-thiopropane

4'-but-3-enyl-4-methyl-2,2'-bipyridinyl
344303-41-9

4'-but-3-enyl-4-methyl-2,2'-bipyridinyl

4-methyl-4'-(4-propylsulfanylbutyl)-2,2'-bipyridinyl

4-methyl-4'-(4-propylsulfanylbutyl)-2,2'-bipyridinyl

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile) In chloroform for 12h; Heating;100%
bis(methanethiolato)bis(dinitrosyliron)

bis(methanethiolato)bis(dinitrosyliron)

1-thiopropane
107-03-9

1-thiopropane

{Fe2(n-C3H7S)2(NO)4}

{Fe2(n-C3H7S)2(NO)4}

Conditions
ConditionsYield
In tetrahydrofuran to soln. of Fe2(CH3S)2(NO)4 in THF is added n-C3H7SH, mixt. is stirred under N2 for 72 h; solvent and volatile products are removed under vac., residue is dissolved in CDCl3 and examined by (1)H NMR;100%
1-thiopropane
107-03-9

1-thiopropane

Gallium trichloride
13450-90-3

Gallium trichloride

(gallium trichloride)propanethiol
98773-06-9

(gallium trichloride)propanethiol

Conditions
ConditionsYield
In benzene under N2, dropwise addn. of thiol soln. to a suspension of GaCl3 in benzene, dissoln. of GaCl3, stirred for 15 min at room temp.; evapn. of solvent, dried in vac. at room temp. for 3h, elem. anal.;100%
1-thiopropane
107-03-9

1-thiopropane

gallium(III) bromide
13450-88-9

gallium(III) bromide

gallium tribromide*1-propanethiol
98773-09-2

gallium tribromide*1-propanethiol

Conditions
ConditionsYield
In benzene under N2, dropwise addn. of thiol soln. to a suspension of GaBr3 in benzene, dissoln. of GaBr3, stirred for 15 min at room temp.; evapn. of solvent, dried in vac. at room temp. for 3h, elem. anal.;100%
1-thiopropane
107-03-9

1-thiopropane

gallium(III) iodide
13450-91-4

gallium(III) iodide

gallium triiodide*1-propanethiol
98773-13-8

gallium triiodide*1-propanethiol

Conditions
ConditionsYield
In benzene under N2, dropwise addn. of thiol soln. to a suspension of GaI3 in benzene, dissoln. of GaI3, stirred for 15 min at room temp.; evapn. of solvent, dried in vac. at room temp. for 3h, elem. anal.;100%
1-thiopropane
107-03-9

1-thiopropane

aluminium(III) iodide
7784-23-8

aluminium(III) iodide

aluminium triodide*1-propanethiol
98773-02-5

aluminium triodide*1-propanethiol

Conditions
ConditionsYield
In benzene under N2, dropwise addn. of thiol soln. to a suspension of AlI3 in benzene, dissoln. of AlI3, stirred for 15 min at room temp.; evapn. of solvent, dried in vac. at room temp. for 3h, elem. anal.;100%
1-thiopropane
107-03-9

1-thiopropane

monomethylgallium di-iodide
95050-66-1

monomethylgallium di-iodide

diiodomethyl(n-propanethiol)gallane

diiodomethyl(n-propanethiol)gallane

Conditions
ConditionsYield
In benzene byproducts: CH4; (under N2); the thiol is introduced into a soln. of MeGaI2 in benzene; the solvent is evapd., the residue is washed, dried; elem. anal.;100%
1-thiopropane
107-03-9

1-thiopropane

N-adamantan-1-yl-2,6-dichloronicotinamide
1024037-69-1

N-adamantan-1-yl-2,6-dichloronicotinamide

N-adamantan-1-yl-6-chloro-2-(propylthio)nicotinamide
1024037-71-5

N-adamantan-1-yl-6-chloro-2-(propylthio)nicotinamide

Conditions
ConditionsYield
With potassium carbonate In propyl cyanide at 20 - 150℃; for 4h;100%
1-thiopropane
107-03-9

1-thiopropane

Dimethylphenylsilane
766-77-8

Dimethylphenylsilane

C11H18SSi
1048375-05-8

C11H18SSi

Conditions
ConditionsYield
With tris(pentafluorophenyl)borate In Petroleum ether at 20℃; for 0.5h;100%
[Ru(2,2':6'2''-terpyridine)(2,2'-bipyridine)(OH2)] hexafluorophosphate

[Ru(2,2':6'2''-terpyridine)(2,2'-bipyridine)(OH2)] hexafluorophosphate

1-thiopropane
107-03-9

1-thiopropane

[Ru(2,2′:6′,2″-terpyridine)(2,2′-bipyridine)(2-methylthioethan-1-ol)](BF4)2

[Ru(2,2′:6′,2″-terpyridine)(2,2′-bipyridine)(2-methylthioethan-1-ol)](BF4)2

Conditions
ConditionsYield
In water at 80℃; for 16h; Inert atmosphere; Darkness;100%
1-thiopropane
107-03-9

1-thiopropane

2-benzylsulfanyl-3-phenylpropenal

2-benzylsulfanyl-3-phenylpropenal

2-(benzylsulfanyl)-3-phenyl-3-(propylsulfanyl)propanal

2-(benzylsulfanyl)-3-phenyl-3-(propylsulfanyl)propanal

Conditions
ConditionsYield
With triethylamine In diethyl ether at 20℃; for 24h;100%
1-thiopropane
107-03-9

1-thiopropane

3-bromobut-3-en-2-one
61203-01-8

3-bromobut-3-en-2-one

3,4-bis(propylsulfanyl)butan-2-one

3,4-bis(propylsulfanyl)butan-2-one

Conditions
ConditionsYield
With triethylamine In diethyl ether at 20℃; for 24h;100%
1-thiopropane
107-03-9

1-thiopropane

dihexyl fumarate
19139-31-2

dihexyl fumarate

dihexyl 2-(propylsulfanyl)succinate

dihexyl 2-(propylsulfanyl)succinate

Conditions
ConditionsYield
With lithium carbonate In ethanol Reagent/catalyst; Solvent; Sealed tube;100%
1-thiopropane
107-03-9

1-thiopropane

C8H7(2)HN(1+)*CF3O3S(1-)

C8H7(2)HN(1+)*CF3O3S(1-)

C11H14(2)H2NS(1+)*CF3O3S(1-)

C11H14(2)H2NS(1+)*CF3O3S(1-)

Conditions
ConditionsYield
With water-d2 In aq. phosphate buffer at 24.84℃; for 0.0666667h; pH=7.6;100%
1-thiopropane
107-03-9

1-thiopropane

Dipropyl disulfide
629-19-6

Dipropyl disulfide

Conditions
ConditionsYield
With 1-n-butyl-3-methylimidazolium methylselenite at 60℃; for 3h;99%
With cerium(III) chloride; iodine; pyrographite In ethyl acetate at 20℃; for 1.5h;97%
With 1,2-bis(5-methylisoxazol-3-yl)hydrazine In acetonitrile at 80℃; for 2h;97%
1-thiopropane
107-03-9

1-thiopropane

4'-nitro-4-toluenesulphenanilide
105731-83-7

4'-nitro-4-toluenesulphenanilide

1-(propyldisulfanyl)-4-methylbenzene
61565-49-9

1-(propyldisulfanyl)-4-methylbenzene

Conditions
ConditionsYield
With potassium carbonate; boron trifluoride diethyl etherate In dichloromethane for 0.0333333h; Ambient temperature;99%
1-thiopropane
107-03-9

1-thiopropane

α-bromoacetophenone
70-11-1

α-bromoacetophenone

1-phenyl-2-(propylthio)ethan-1-one
14680-00-3

1-phenyl-2-(propylthio)ethan-1-one

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran at 20℃; Inert atmosphere;99%
1-thiopropane
107-03-9

1-thiopropane

propionaldehyde
123-38-6

propionaldehyde

1,1-bis-propylsulfanyl-propane
32907-41-8

1,1-bis-propylsulfanyl-propane

Conditions
ConditionsYield
With indium(III) bromide In dichloromethane at 20℃; for 0.25h;99%
1-thiopropane
107-03-9

1-thiopropane

pivalaldehyde
630-19-3

pivalaldehyde

2,2-dimethyl-1,1-bis-propylsulfanyl-propane

2,2-dimethyl-1,1-bis-propylsulfanyl-propane

Conditions
ConditionsYield
With indium(III) bromide In dichloromethane at 20℃; for 0.5h;99%
1-thiopropane
107-03-9

1-thiopropane

3-phenyl-propenal
104-55-2

3-phenyl-propenal

((E)-3,3-Bis-propylsulfanyl-propenyl)-benzene

((E)-3,3-Bis-propylsulfanyl-propenyl)-benzene

Conditions
ConditionsYield
With indium(III) bromide In dichloromethane at 20℃; for 1h;99%
1-ferrocenylmethanol
1273-86-5

1-ferrocenylmethanol

1-thiopropane
107-03-9

1-thiopropane

C10H9FeCH2S-(n-C3H7)

C10H9FeCH2S-(n-C3H7)

Conditions
ConditionsYield
With CF3COOH or CH3COOH presence of CF3COOH or CH3COOH;99%
1-thiopropane
107-03-9

1-thiopropane

sym-methoxy[N,N'-bis(salicylidene)-1,3-diaminopropanato]oxorhenium
212496-48-5

sym-methoxy[N,N'-bis(salicylidene)-1,3-diaminopropanato]oxorhenium

non-sym-propylthio[N,N'-bis(salicylidene)-1,3-diaminopropanato]oxorhenium

non-sym-propylthio[N,N'-bis(salicylidene)-1,3-diaminopropanato]oxorhenium

Conditions
ConditionsYield
In dichloromethane byproducts: MeOH; excess thiol, refluxing for 12 h (trapping MeOH with 4 A molecular sives); cooling to room temp., washing (1 M NaOH, brine), drying (MgSO4), solvent removal (vac.);99%
1-thiopropane
107-03-9

1-thiopropane

1,4-difluoro-2-nitrobenzene
364-74-9

1,4-difluoro-2-nitrobenzene

4-fluoro-2-nitro-1-propylsulfanylbenzene
1092496-25-7

4-fluoro-2-nitro-1-propylsulfanylbenzene

Conditions
ConditionsYield
With potassium carbonate In 1-methyl-pyrrolidin-2-one at 90℃; for 2h;99%
1-thiopropane
107-03-9

1-thiopropane

N-(2,2,2-trifluoroethylidene)-4-methoxyaniline
99333-34-3

N-(2,2,2-trifluoroethylidene)-4-methoxyaniline

(R)-4-methoxy-N-(2,2,2-trifluoro-1-(propylthio)ethyl)aniline
1454268-32-6

(R)-4-methoxy-N-(2,2,2-trifluoro-1-(propylthio)ethyl)aniline

Conditions
ConditionsYield
With C31H26F6N4O2 In dichloromethane at 20℃; enantioselective reaction;99%
1-thiopropane
107-03-9

1-thiopropane

octavinylsilsesquioxane
69655-76-1

octavinylsilsesquioxane

octa(2-(propylthio)ethyl)octasilsesquioxane

octa(2-(propylthio)ethyl)octasilsesquioxane

Conditions
ConditionsYield
With 2,2'-azobis(isobutyronitrile) In toluene at 60℃; for 17h; Inert atmosphere;99%
1-thiopropane
107-03-9

1-thiopropane

phenyl methacrylate
2177-70-0

phenyl methacrylate

phenyl (2R)-2-methyl-3-(propylsulfanyl)propanoate

phenyl (2R)-2-methyl-3-(propylsulfanyl)propanoate

Conditions
ConditionsYield
With C47H57N4O4PS In diethyl ether at 20℃; for 24h; Solvent; Temperature; Michael Addition; enantioselective reaction;99%

1-Propanethiol Chemical Properties

Molecular Structure of 1-Propanethiol (CAS NO.107-03-9):

IUPAC Name: Propane-1-thiol
Canonical SMILES: CCCS
InChI: InChI=1S/C3H8S/c1-2-3-4/h4H,2-3H2,1H3
InChIKey: SUVIGLJNEAMWEG-UHFFFAOYSA-N
Molecular Weight: 76.16062 [g/mol]
Molecular Formula: C3H8S
XLogP3: 1.8 
EINECS: 203-455-5
Product Categories: thiol Flavor
Index of Refraction: 1.431
Surface Tension: 23.7 dyne/cm
Density: 0.826 g/cm3
Flash Point: -5 °F
Melting point: -113 °C
Enthalpy of Vaporization: 29.54 kJ/mol
Boiling Point: 67.8 °C at 760 mmHg
Vapour Pressure: 156 mmHg at 25 °C
Storage temp: Flammables area
Water Solubility : immiscible.
Appearance: clear colourless liquid.
Classification Code: Skin / Eye Irritant 

1-Propanethiol Uses

 1-Propanethiol (CAS NO.107-03-9) can be used as raw materials of organic synthesis, is also a pesticide intermediate.

1-Propanethiol Production

 1-Propanethiol (CAS NO.107-03-9)derived by the reaction of thiourea with bromopropane .
Thiourea with bromine in methanol solution, refluxed 3h, recovery of methanol, add dilute sodium hydroxide solution and then refluxed 6h.Then, slowly drop dilute sulfuric acid, with the increase steamed out Propanethiol, when the sulfuric acid plus finished, continue distillation until no oil is up steamed. Collected the crude oil layer, drying with anhydrous calcium chloride, and then distillation, collecting (Boiling point : 66.5 ~ 76.5 °C ) distillation ,which is 1-Propanethiol (CAS NO.107-03-9).

1-Propanethiol Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LC50 inhalation 4010ppm/4H (4010ppm) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SENSE ORGANS AND SPECIAL SENSES: CHROMODACYRORREA: EYE
American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
rat LC50 inhalation 7300ppm/4H (7300ppm) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION

BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE
American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
rat LD50 intraperitoneal 515mg/kg (515mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: COMA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.
rat LD50 oral 1790mg/kg (1790mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION

BEHAVIORAL: COMA
American Industrial Hygiene Association Journal. Vol. 19, Pg. 171, 1958.

1-Propanethiol Safety Profile

A poison. Moderately toxic by intraperitoneal route. Mildly toxic by inhalation. A severe eye irritant. A flammable liquid and very dangerous fire hazard when exposed to heat or flame. Explodes on contact with calcium hypochlorite. When heated to decomposition it emits toxic fumes of SOx.
Hazard Codes: FlammableF,HarmfulXn,DangerousN
Risk Statements: 11-41-50-36/37/38-21/22 
R11:Highly flammable. 
R41:Risk of serious damage to the eyes. 
R50:Very toxic to aquatic organisms. 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R21/22:Harmful in contact with skin and if swallowed.
Safety Statements: 16-26-57-36/37/39-29 
S16:Keep away from sources of ignition. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S29:Do not empty into drains. 
S57:Use appropriate container to avoid environmental contamination. 
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 2402 3/PG 2
WGK Germany: 3
RTECS: TZ7300000
F: 13
HazardClass: 3
PackingGroup: II

1-Propanethiol Specification

 1-Propanethiol (CAS NO.107-03-9), its Synonyms are 1-Mercaptopropane ; 1-Propyl mercaptan ; Propyl mercaptan ; Propylthiol ; n-Propanethiol ; n-Propyl mercaptan ; n-Propylthiol .

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